Local hydrogen clearance as a method for the measurement of capillary blood flow.

Abstract:

:A hydrogen clearance technique for the measurement of capillary blood flow in skeletal muscle (both resting and working) and the beating heart in experimental animals is described. Various methods for introducing the hydrogen into the region of measurement are compared, together with the appropriate methods for evaluating the resultant curves. All methods yielded results which were proportional to each other signifying that this is a reliable method for measuring changes in capillary blood flow. Reproducible results were obtained, and physiological changes in flow could be easily detected. An approach towards obtaining absolute flow values is proposed by simultaneous measurement of the arterial input function together with the independent use of other indicators.

journal_name

Phys Med Biol

authors

Harrison DK,Kessler M

doi

10.1088/0031-9155/34/10/005

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

1413-28

issue

10

eissn

0031-9155

issn

1361-6560

journal_volume

34

pub_type

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