Abstract:
:The radiofrequency dielectric behaviour of packed human erythrocytes has been investigated in normal haemoglobins F and AA and also abnormal haemoglobins homozygous SS and heterozygous AS. Dielectric measurements were made in tightly packed blood cells at an average room temperature of 26.5 +/- 0.5 degrees C in the frequency range from 0.1 to 100 MHz. In agreement with previous findings in many biological molecules, all the packed erythrocytes of the different haemoglobins exhibited a decrease in dielectric constant and an increase in conductivity with frequency. However, each type has been found to show distinct dielectric dispersion with respect to the others and this has been associated with their molecular structure in addition to the polarization of cell membrane. The possible application of this technique in identifying different haemoglobins of the blood has been suggested.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Laogun AA,Ajayi NO,Okafor LO,Osamo NOdoi
10.1088/0031-9155/28/4/002subject
Has Abstractpub_date
1983-04-01 00:00:00pages
341-9issue
4eissn
0031-9155issn
1361-6560journal_volume
28pub_type
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