Dielectric characteristics of packed human erythrocytes with haemoglobins F, AA, AS and SS.

Abstract:

:The radiofrequency dielectric behaviour of packed human erythrocytes has been investigated in normal haemoglobins F and AA and also abnormal haemoglobins homozygous SS and heterozygous AS. Dielectric measurements were made in tightly packed blood cells at an average room temperature of 26.5 +/- 0.5 degrees C in the frequency range from 0.1 to 100 MHz. In agreement with previous findings in many biological molecules, all the packed erythrocytes of the different haemoglobins exhibited a decrease in dielectric constant and an increase in conductivity with frequency. However, each type has been found to show distinct dielectric dispersion with respect to the others and this has been associated with their molecular structure in addition to the polarization of cell membrane. The possible application of this technique in identifying different haemoglobins of the blood has been suggested.

journal_name

Phys Med Biol

authors

Laogun AA,Ajayi NO,Okafor LO,Osamo NO

doi

10.1088/0031-9155/28/4/002

subject

Has Abstract

pub_date

1983-04-01 00:00:00

pages

341-9

issue

4

eissn

0031-9155

issn

1361-6560

journal_volume

28

pub_type

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