Real-time motion-adaptive-optimization (MAO) in TomoTherapy.

abstract：:Methods based on magnetic resonance imaging for the measurement of three-dimensional distributions of radiation dose are highly developed. However, relatively little work has been done on optical computed tomography (OCT). This paper describes a new OCT scanner based on a broad beam light source and a two-dimensional ...

journal_title：Physics in medicine and biology

authors： Doran SJ,Koerkamp KK,Bero MA,Jenneson P,Morton EJ,Gilboy WB

更新日期：2001-12-01 00:00:00

abstract：:Dose calculations were performed for a tissue phantom irradiated by uniform circular beams of negative pions with an assumed gaussian momentum distribution. The mean momentum of the pions was varied from 104.4 to 171.5 MeV/c (mean range 5-20 cm in unit-density tissue) and the momentum spread from 0 to 5% of the mean. ...

journal_title：Physics in medicine and biology

authors： Hamm RN,Wright HA,Turner JE

更新日期：1979-05-01 00:00:00

abstract：:An inverse radiation treatment planning algorithm for Sensus Healthcare's SculpturaTM electronic brachytherapy system has been designed. The algorithm makes use of simulated annealing to optimize the conformation number of the treatment plan. The highly anisotropic dose distributions produced by the SculpturaTM x-ray ...

journal_title：Physics in medicine and biology

authors： Badali DS,Vainer Y,Ellenor CW,Mitchell CR,Fishman K,Soro N,Price R,Funk T

更新日期：2021-01-11 00:00:00

abstract：:It has been reported that the dose effects of metallic guidewires are significant in intravascular brachytherapy (IVBT) using a beta source. The purpose of this work is to investigate the dependence of these dose effects on guidewire position. The EGS4 Monte Carlo codes were used to perform the dose calculations for t...

journal_title：Physics in medicine and biology

authors： Shih R,Hsu WL,Li XA

更新日期：2002-05-21 00:00:00

abstract：:The dose-response of LiF:Mg,Ti (TLD-100) exposed to 15 and 35 kVp (8.0 +/- 0.1 and 8.1 +/- 0.1 keV effective energy respectively) x-rays and 60Co gamma-rays has been measured in the dose interval from (1.2-5.4) x 10(3) Gy for x-rays, and from 0.14 to 850 Gy for gamma-rays. In both cases the total TL signal and glow cu...

journal_title：Physics in medicine and biology

authors： Gamboa-deBuen I,Buenfil AE,Ruiz CG,Rodríguez-Villafuerte M,Flores A,Brandan ME

更新日期：1998-08-01 00:00:00

abstract：:Average penetration depths and detour factors of 1-50 MeV electrons in water and plastic materials have been computed by means of analytical calculation, within the continuous-slowing-down approximation and including multiple scattering, and using the Monte Carlo codes ITS and PENELOPE. Results are compared to detour ...

journal_title：Physics in medicine and biology

authors： Fernández-Varea JM,Andreo P,Tabata T

更新日期：1996-07-01 00:00:00

abstract：:Respiratory-correlated 4D-MRI can characterize respiratory-induced motion of tumors and organs-at-risk for radiotherapy treatment planning and is a necessity for image guidance of moving tumors treated on an MRI-linac. Essential for 4D-MRI generation is a robust respiratory surrogate signal. We investigated the feasib...

journal_title：Physics in medicine and biology

authors： Navest RJM,Mandija S,Bruijnen T,Stemkens B,Tijssen RHN,Andreychenko A,Lagendijk JJW,van den Berg CAT

更新日期：2020-01-13 00:00:00

abstract：:Complex intra-fractional motion and deformation of the liver significantly impacts the accuracy of delivered dose in radiotherapy. It limits margin reduction, dose escalation and normal tissue sparing. A critical component of motion management is to accurately reconstruct tumor motion. In this study, we developed a si...

journal_title：Physics in medicine and biology

authors： Chi Y,Shen C,Li B,Zhang Y,Yang M,Folkert M,Jia X

更新日期：2019-11-21 00:00:00

abstract：:Tserng and Kalhan have raised the question of the appropriate equation to use for the measurement of turnover rate in a stable-isotope study. In a comparison of glucose turnover measured with 2H-glucose and with 13C-glucose they used five apparently different equations and obtained conflicting answers. There is, howev...

journal_title：Physics in medicine and biology

authors： Wootton R,Ford GC,Cheng KN,Halliday D

更新日期：1985-10-01 00:00:00

abstract：:We examined the reasons for the reduction in response of a multidetector radiation counting system when operated at high count-rates and established a convenient method of correction which is accurate to within +/- 1% up to 0-6 X 10(5) counts per second. In its application the method uses the observed count-rates from...

journal_title：Physics in medicine and biology

authors： Oxby CB,Oldroyd B,Appleby DB

更新日期：1976-01-01 00:00:00

abstract：:The treatment delivery time of intensity-modulated radiation therapy (IMRT) with a multileaf collimator (MLC) is generally longer than that of conventional radiotherapy. In theory, removing the flattening filter from the treatment head may reduce the beam-on time by enhancing the output dose rate, and then reduce the ...

journal_title：Physics in medicine and biology

authors： Fu W,Dai J,Hu Y,Han D,Song Y

更新日期：2004-04-21 00:00:00

abstract：:With the development of laser technology, laser-driven proton acceleration provides a new method for proton tumor therapy. However, it has not been applied in practice because of the wide and decreasing energy spectrum of laser-accelerated proton beams. In this paper, we propose an analytical model to reconstruct the ...

journal_title：Physics in medicine and biology

authors： Tao L,Zhu K,Zhu J,Xu X,Lin C,Ma W,Lu H,Zhao Y,Lu Y,Chen JE,Yan X

更新日期：2017-07-07 00:00:00

abstract：:X-ray scatter is a significant problem in cone-beam computed tomography when thicker objects and larger cone angles are used, as scattered radiation can lead to reduced contrast and CT number inaccuracy. Advances have been made in x-ray computed tomography (CT) by incorporating a high quality prior image into the imag...

journal_title：Physics in medicine and biology

authors： Brunner S,Nett BE,Tolakanahalli R,Chen GH

更新日期：2011-02-21 00:00:00

abstract：:The aim of this study is to calculate realistic dose distributions that include the continuous deformation of organs and continuous motion of machine using 4D Monte Carlo methods for both volumetric modulated arc therapy and helical tomotherapy treatments. As part of a previous study, we presented a method to perform ...

journal_title：Physics in medicine and biology

authors： Belec J,Clark BG

更新日期：2013-05-07 00:00:00

abstract：:Absorption and emission optical projection tomography (OPT), alternatively referred to as optical computed tomography (optical-CT) and optical-emission computed tomography (optical-ECT), are recently developed three-dimensional imaging techniques with value for developmental biology and ex vivo gene expression studies...

journal_title：Physics in medicine and biology

authors： Fumene Feruglio P,Vinegoni C,Gros J,Sbarbati A,Weissleder R

更新日期：2010-09-21 00:00:00

abstract：:The enormous advances in the understanding of human anatomy, physiology and pathology in recent decades have led to ever-improving methods of disease prevention, diagnosis and treatment. Many of these achievements have been enabled, at least in part, by advances in ionizing radiation detectors. Radiology has been tran...

journal_title：Physics in medicine and biology

authors： Seco J,Clasie B,Partridge M

更新日期：2014-10-21 00:00:00

abstract：:Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of disease and in situ evaluation of living tissue. The purpose of this article is to review the biological and physical basis of Raman spectroscopy of tissue, to assess the current status of the field and to explore future directions....

journal_title：Physics in medicine and biology

authors： Hanlon EB,Manoharan R,Koo TW,Shafer KE,Motz JT,Fitzmaurice M,Kramer JR,Itzkan I,Dasari RR,Feld MS

更新日期：2000-02-01 00:00:00

abstract：:The aim of this study is to investigate the use of mathematical morphology for the determination of left ventricular contours in scintigraphic images using multigated radionuclide angiography. We have developed a completely automatic method that first restores the image with a Wiener filter, then finds the region wher...

journal_title：Physics in medicine and biology

authors： Pladellorens J,Serrat J,Castell A,Yzuel MJ

更新日期：1993-12-01 00:00:00

abstract：:A complete characterization of spongiosa (bone marrow plus trabecular bone) is required to calculate the absorbed dose to active bone marrow. Due to the complex microanatomy, it is necessary to apply non-conventional imaging methods in nuclear medicine. The aim of this study is validating a phantomless quantification ...

journal_title：Physics in medicine and biology

authors： Salas-Ramirez M,Tran-Gia J,Gbureck U,Kosmala A,Lassmann M

更新日期：2019-10-16 00:00:00

abstract：:Simultaneous rest perfusion/fatty-acid metabolism studies have the potential to replace sequential rest/stress perfusion studies for the assessment of cardiac function. Simultaneous acquisition has the benefits of increased signal and lack of need for patient stress, but is complicated by cross-talk between the two ra...

journal_title：Physics in medicine and biology

authors： Trott CM,Ouyang J,El Fakhri G

更新日期：2010-11-21 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00

abstract：:Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...

journal_title：Physics in medicine and biology

authors： Holbrook M,Clark DP,Badea CT

更新日期：2018-01-09 00:00:00

abstract：:A CT scanner has been constructed specifically to determine the three-dimensional distribution of bone mineral in the medullary cavities of the radius, ulna and femur. A source of x-rays (153Gd) and a multiwire proportional counter (MWPC) are mounted at opposite ends of a diameter of an annular mounting. The limb is p...

journal_title：Physics in medicine and biology

authors： Horsman A,Sutcliffe J,Burkinshaw L,Wild P,Skilling J,Webb S

更新日期：1987-10-01 00:00:00

abstract：:This study investigated the relationship between the specific absorption rate and temperature elevation in an anatomically-based model named NORMAN for exposure to radio-frequency far fields in the ICNIRP guidelines (1998 Health Phys. 74 494-522). The finite-difference time-domain method is used for analyzing the elec...

journal_title：Physics in medicine and biology

authors： Hirata A,Asano T,Fujiwara O

更新日期：2007-08-21 00:00:00

abstract：:Proton computed tomography (pCT) promises to reduce or even eliminate range uncertainties inherent in the conversion of Hounsfield units into relative stopping power (RSP) for proton therapy treatment planning. This is of particular interest for proton irradiation studies in animal models due to the high precision req...

journal_title：Physics in medicine and biology

authors： Meyer S,Bortfeldt J,Lämmer P,Englbrecht FS,Pinto M,Schnürle K,Würl M,Parodi K

更新日期：2020-08-13 00:00:00

abstract：:We explore how the radioactive background from naturally occurring 176Lu affects single photon transmission imaging for lutetium orthosilicate (LSO) scintillator-based PET cameras by estimating the transmission noise equivalent count rate (NECR) including this background. Assuming a typical PET camera geometry (80 cm ...

journal_title：Physics in medicine and biology

authors： Huber JS,Moses WW,Jones WF,Watson CC

更新日期：2002-10-07 00:00:00

abstract：:The 0.35 T 60Co MRIdian system (ViewRay Inc., Mountain View) has been in clinical use in our institution since May 2016. For quality assurance (QA) of dose delivery and end-to-end testing for this machine, a reliable dosimeter is required. However, it is possible that a magnetic field may cause perturbations to dosime...

journal_title：Physics in medicine and biology

authors： Barten DLJ,Hoffmans D,Palacios MA,Heukelom S,van Battum LJ

更新日期：2018-08-20 00:00:00

abstract：:In stereotactic radiosurgery, a seven-irradiation film was used to define any discrepancy between the beam and target centres. A mathematical model based on the linac alignment and target set-up was developed to diagnose the discrepancies of the seven-irradiation film between the beam and simulation target centres. Fr...

journal_title：Physics in medicine and biology

authors： Tsai JS

更新日期：1996-09-01 00:00:00

abstract：:This paper describes a neural network (NN) regression model for relative dose computation. The input signal of the NN model includes depths and field sizes and the output is the relative dose, for example, percentage depth dose (%DD) or tissue-air ratio (TAR) in this paper. After a functional link has been created, th...

journal_title：Physics in medicine and biology

authors： Wu X,Zhu Y

更新日期：2000-04-01 00:00:00

abstract：:We propose bilinear models for capturing and effectively decoupling the expected shape variations of an organ both across the patient population and within a specific patient. Bilinear models have been successfully introduced in other areas of computer vision, but they have rarely been used in medical imaging applicat...

journal_title：Physics in medicine and biology

authors： Jeong Y,Radke RJ,Lovelock DM

更新日期：2010-07-07 00:00:00