Directional x-ray dark-field imaging.

abstract：:As a new method, x-ray diffraction enhanced imaging (DEI) has extremely high sensitivity for weakly absorbing low-Z samples in medical and biological fields. Conventional performance parameters, such as spatial resolution and low-contrast resolution, are not enough to describe the characteristics of a DEI system. This...

journal_title：Physics in medicine and biology

authors： Huang ZF,Kang KJ,Li Z

更新日期：2006-06-21 00:00:00

abstract：:An optimized configuration of multi-pinhole aperture can improve the spatial resolution and the sensitivity of pinhole SPECT simultaneously. In this study, an optimization strategy of the multi-pinhole configuration with a small detector is proposed for mouse cardiac imaging. A 14 mm-diameter spherical field-of-view (...

journal_title：Physics in medicine and biology

authors： Lee MW,Lin WT,Chen YC

更新日期：2015-01-21 00:00:00

abstract：:A parametric model for the x-ray linear attenuation coefficient is used to describe the compositional dependence of Hounsfield numbers measured by medical CT scanners. Measurements with materials of known density and composition, that span and evenly sample the compositional range of tissues, are written as linear sim...

journal_title：Physics in medicine and biology

authors： Midgley SM

更新日期：2014-12-07 00:00:00

abstract：:Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for bot...

journal_title：Physics in medicine and biology

authors： Gustafsson CJ,Swärd J,Adalbjörnsson SI,Jakobsson A,Olsson LE

更新日期：2020-11-12 00:00:00

abstract：:The purpose of this study was to examine the use of three physical image quality metrics in the calibration of an automatic exposure control (AEC) device for chest radiography with a computed radiography (CR) imaging system. The metrics assessed were signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and mean ...

journal_title：Physics in medicine and biology

authors： Moore CS,Wood TJ,Avery G,Balcam S,Needler L,Beavis AW,Saunderson JR

更新日期：2014-05-07 00:00:00

abstract：:The classical Sievert integral method is a valuable tool for dose rate calculations around brachytherapy sources, combining simplicity with reasonable computational times. However, its accuracy in predicting dose rate anisotropy around 192Ir brachytherapy sources has been repeatedly put into question. In this work, we...

journal_title：Physics in medicine and biology

authors： Karaiskos P,Angelopoulos A,Baras P,Rozaki-Mavrouli H,Sandilos P,Vlachos L,Sakelliou L

更新日期：2000-02-01 00:00:00

abstract：:Statistically based iterative image reconstruction methods have been developed for emission tomography. One important component in iterative image reconstruction is the system matrix, which defines the mapping from the image space to the data space. Several groups have demonstrated that an accurate system matrix can i...

journal_title：Physics in medicine and biology

authors： Qi J,Huesman RH

更新日期：2005-07-21 00:00:00

abstract：:Recent theoretical research on spatiobiologically integrated radiotherapy has focused on optimization models that adapt fluence-maps to the evolution of tumor state, for example, cell densities, as observed in quantitative functional images acquired over the treatment course. We propose an optimization model that adap...

journal_title：Physics in medicine and biology

authors： Ajdari A,Ghate A,Kim M

更新日期：2018-03-27 00:00:00

abstract：:Monte Carlo simulations are used to investigate skin dose resulting from chest wall radiotherapy with bolus. A simple model of a female thorax is developed, which includes a 2 mm-thick skin layer. Two representative 6 MV source models are considered: a tangents source model consisting of a parallel opposed pair of med...

journal_title：Physics in medicine and biology

authors： Oliver PAK,Monajemi TT

更新日期：2020-08-11 00:00:00

abstract：:We propose a completely automated algorithm for the detection of the spinal centreline and the centres of vertebral bodies and intervertebral discs in images acquired by computed tomography (CT) and magnetic resonance (MR) imaging. The developed methods are based on the analysis of the geometry of spinal structures an...

journal_title：Physics in medicine and biology

authors： Stern D,Likar B,Pernus F,Vrtovec T

更新日期：2010-01-07 00:00:00

abstract：:Images of the human retina are routinely used in clinical practice for the diagnosis and management of eye disease. Increased permeability of retinal blood vessels, which is a clinically significant feature, can be visualized with a process known as fluorescein angiography as leakage of fluorescence dye into the surro...

journal_title：Physics in medicine and biology

authors： Cree MJ,Olson JA,McHardy KC,Sharp PF,Forrester JV

更新日期：1999-01-01 00:00:00

abstract：:The architecture of multi-layer imagers (MLIs) can be exploited to provide megavoltage spectral imaging (MVSPI) for specific imaging tasks. In the current work, we investigated bone suppression and gold fiducial contrast enhancement as two clinical tasks which could be improved with spectral imaging. A method based on...

journal_title：Physics in medicine and biology

authors： Myronakis M,Hu YH,Fueglistaller R,Wang A,Baturin P,Huber P,Morf D,Star-Lack J,Berbeco R

更新日期：2018-05-10 00:00:00

abstract：:Densitometric quantification of coronary artery stenoses in angiographic images can be problematic for two reasons: (i) the x-rays are inadequately oriented with respect to the vessel segments of interest at image acquisition; (ii) non-linear effects due for instance to beam hardening, scattered radiation and veiling ...

journal_title：Physics in medicine and biology

authors： Doriot PA,Dorsaz PA,Dorsaz L,Bodenmann JJ

更新日期：1997-12-01 00:00:00

abstract：:Biomedical fibre-optic sensors are attractive for the measurement of physical, chemical and biochemical parameters and for spectral measurements directly performed on the patient. An overview of fibre-optic sensors for in vivo monitoring is given, with particular attention paid to the advantages that these sensors are...

journal_title：Physics in medicine and biology

authors： Mignani AG,Baldini F

更新日期：1997-05-01 00:00:00

abstract：:A phantom study was performed in full-field digital mammography to investigate the opportunity and the magnitude of a possible dose reduction that would leave the image quality above the accepted thresholds associated with some classical phantoms. This preliminary work is intended to lay the groundwork for a future cl...

journal_title：Physics in medicine and biology

authors： Gennaro G,Katz L,Souchay H,Alberelli C,di Maggio C

更新日期：2005-04-21 00:00:00

abstract：:An in vivo probe was compared with a gamma camera for the task of detecting radiolabelled tumour models in a water phantom. The probe, which contained a 1 cm diameter NaI(T1) detector, was designed and used by us for surgical staging studies of gynaecological patients. Tumours were spherical sources of different sizes...

journal_title：Physics in medicine and biology

authors： Barber HB,Barrett HH,Woolfenden JM,Myers KJ,Hickernell TS

更新日期：1989-06-01 00:00:00

abstract：:Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of disease and in situ evaluation of living tissue. The purpose of this article is to review the biological and physical basis of Raman spectroscopy of tissue, to assess the current status of the field and to explore future directions....

journal_title：Physics in medicine and biology

authors： Hanlon EB,Manoharan R,Koo TW,Shafer KE,Motz JT,Fitzmaurice M,Kramer JR,Itzkan I,Dasari RR,Feld MS

更新日期：2000-02-01 00:00:00

abstract：:A new component module (CM), designated DYNVMLC, was developed to fully model the geometry of the Varian Millennium 120 leaf collimator using the BEAMnrc Monte Carlo code. The model includes details such as the leaf driving screw hole, support railing groove and leaf tips. Further modifications also allow sampling of ...

journal_title：Physics in medicine and biology

authors： Heath E,Seuntjens J

更新日期：2003-12-21 00:00:00

abstract：:4D cone beam computed tomography (4DCBCT) is an emerging image guidance strategy used in radiotherapy where projections acquired during a scan are sorted into respiratory bins based on the respiratory phase or displacement. 4DCBCT reduces the motion blur caused by respiratory motion but increases streaking artefacts d...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Kipritidis J,Shieh CC,Keall PJ

更新日期：2014-10-07 00:00:00

abstract：:The probability of a photon (x-ray, gamma-ray, bremsstrahlung, etc) of a given energy E undergoing absorption or scattering when traversing a layer of material Z can be expressed quantitatively in terms of a linear attenuation coefficient mu (cm(-1)). Since mu is dependent on the material's density, rho (g cm(-3)), wh...

journal_title：Physics in medicine and biology

authors： Hubbell JH

更新日期：1999-01-01 00:00:00

abstract：:The low energy model of the GEANT4 Monte Carlo toolkit was used to simulate the energy response of a T.P.A. Mk-II ionization chamber under a variety of different conditions. The sample position resulting in the maximum response along the axial direction of the chamber was obtained. The parameters of the simulation wer...

journal_title：Physics in medicine and biology

authors： Seneviratne MD,Reinhard MI,Baldock C

更新日期：2007-07-07 00:00:00

abstract：:We developed and validated a Monte-Carlo-based application (RAYDOSE) to generate patient-specific 3D dose maps on the basis of pre-treatment imaging studies. A CT DICOM image is used to model patient geometry, while repeated PET scans are employed to assess radionuclide kinetics and distribution at the voxel level. In...

journal_title：Physics in medicine and biology

authors： Marcatili S,Pettinato C,Daniels S,Lewis G,Edwards P,Fanti S,Spezi E

更新日期：2013-04-21 00:00:00

abstract：:Photon quality correction factors (kQy) for ionization chamber photon dosimetry in an epithermal neutron beam were determined according to a modified absorbed dose to water formalism which was extended to mixed radiation fields. We have studied two commercially available ionization chambers in the epithermal neutron b...

journal_title：Physics in medicine and biology

authors： Munck af Rosenschöld PM,Ceberg CP,Giusti V,Andreo P

更新日期：2002-07-21 00:00:00

abstract：:We present the results of utilizing aligned anatomical information from CT images to locally adjust image smoothness during the reconstruction of three-dimensional (3D) whole-body positron emission tomography (PET) data. The ability of whole-body PET imaging to detect malignant neoplasms is becoming widely recognized....

journal_title：Physics in medicine and biology

authors： Comtat C,Kinahan PE,Fessler JA,Beyer T,Townsend DW,Defrise M,Michel C

更新日期：2002-01-07 00:00:00

abstract：:Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality of any automatic registration procedure has been a challenging part because no gold standard is available to e...

journal_title：Physics in medicine and biology

authors： Ceylan C,van der Heide UA,Bol GH,Lagendijk JJ,Kotte AN

更新日期：2005-05-21 00:00:00

abstract：:A Monte Carlo model of a novel electronic portal imaging device (EPID) has been developed using Geant4 and its performance for imaging and dosimetry applications in radiotherapy has been characterised. The EPID geometry is based on a physical prototype under ongoing investigation and comprises an array of plastic scin...

journal_title：Physics in medicine and biology

authors： Blake SJ,McNamara AL,Vial P,Holloway L,Kuncic Z

更新日期：2014-11-21 00:00:00

abstract：:The use of calibrated tissue-equivalent (TE) ionisation chambers is commonly considered to be the most practical method for total absorbed dose determinations in mixed neutron-photon fields for biomedical applications. The total absorbed dose can be derived from the charge produced within the cavity of an ionisation c...

journal_title：Physics in medicine and biology

authors： Zoetelief J,Broerse JJ

更新日期：1983-05-01 00:00:00

abstract：:A medical research protocol on clinical intravenous coronary angiography has been completed at the European Synchrotron Radiation Facility (ESRF) biomedical beamline. The aim was to investigate the accuracy of intravenous coronary angiography based on the K-edge digital subtraction technique for the detection of in-st...

journal_title：Physics in medicine and biology

authors： Sarnelli A,Nemoz C,Elleaume H,Estève F,Bertrand B,Bravin A

更新日期：2005-02-21 00:00:00

abstract：:Gel dosimetry based on magnetic resonance imaging (MRI) has previously been shown to provide verification of calculated dose distributions in soft tissue equivalent homogeneous phantoms. This study demonstrates how measurements of dose distribution can also be achieved in a phantom containing porous, lung-equivalent, ...

journal_title：Physics in medicine and biology

authors： Olberg S,Skretting A,Bruland O,Olsen DR

更新日期：2000-10-01 00:00:00

abstract：:We used a real-skull phantom head to investigate the performances of representative methods for EEG source localization when considering various head models. We describe several experiments using a montage with current sources located at multiple positions and orientations inside a human skull filled with a conductive...

journal_title：Physics in medicine and biology

authors： Baillet S,Riera JJ,Marin G,Mangin JF,Aubert J,Garnero L

更新日期：2001-01-01 00:00:00