Abstract:
:A medical research protocol on clinical intravenous coronary angiography has been completed at the European Synchrotron Radiation Facility (ESRF) biomedical beamline. The aim was to investigate the accuracy of intravenous coronary angiography based on the K-edge digital subtraction technique for the detection of in-stent restenosis. For each patient, diagnosis has been performed on the synchrotron radiation images and monitored with the conventional selective coronary angiography method taken as the golden standard. In this paper, the methods of image processing and the results of the quantitative analysis are described. Image processing includes beam harmonic contamination correction, spatial deconvolution and the extraction of a 'contrast' and a 'tissue' image from each couple of radiograms simultaneously acquired at energies bracketing the K-edge of iodine. Quantitative analysis includes the estimation of the vessel diameter, the calculation of the absolute iodine concentration profiles along the coronary arteries and the stenosis degree measurement.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Sarnelli A,Nemoz C,Elleaume H,Estève F,Bertrand B,Bravin Adoi
10.1088/0031-9155/50/4/011subject
Has Abstractpub_date
2005-02-21 00:00:00pages
725-40issue
4eissn
0031-9155issn
1361-6560journal_volume
50pub_type
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