Development and validation of RAYDOSE: a Geant4-based application for molecular radiotherapy.

abstract：PURPOSE:A system for long-length intraoperative imaging is reported based on longitudinal motion of an O-arm gantry featuring a multi-slot collimator. We assess the utility of long-length tomosynthesis and the geometric accuracy of 3D image registration for surgical guidance and evaluation of long spinal constructs. M...

journal_title：Physics in medicine and biology

authors： Zhang X,Uneri A,Wu P,Ketcha MD,Jones C,Huang Y,Lo SL,Helm PA,Siewerdsen JH

更新日期：2021-01-21 00:00:00

abstract：:Radiation dose calculation using models of the human anatomy has been a subject of great interest to radiation protection, medical imaging, and radiotherapy. However, early pioneers of this field did not foresee the exponential growth of research activity as observed today. This review article walks the reader through...

journal_title：Physics in medicine and biology

authors： Xu XG

更新日期：2014-09-21 00:00:00

abstract：:The purpose of this study was to determine the performance of a single lutetium oxy-orthosilicate (LSO) crystal layer High Resolution Research Tomograph (HRRT) positron emission tomography (PET) scanner. The HRRT is a high resolution PET scanner designed for human brain and small animal imaging. The scanner consists o...

journal_title：Physics in medicine and biology

authors： Boellaard R,Buijs F,de Jong HW,Lenox M,Gremillion T,Lammertsma AA

更新日期：2003-02-21 00:00:00

abstract：:A pencil beam model for the calculation of the lateral scattering in water of protons for any therapeutic energy and depth is presented. It is based on the full Molière theory, taking into account the energy loss and the effects of mixtures and compounds. Concerning the electromagnetic part, the model has no free para...

journal_title：Physics in medicine and biology

authors： Bellinzona EV,Ciocca M,Embriaco A,Ferrari A,Fontana A,Mairani A,Parodi K,Rotondi A,Sala P,Tessonnier T

更新日期：2016-02-21 00:00:00

abstract：:A method will be described for determining the centre of rotation of a mechanically scanned reflection ultrasound computed tomography system. It is based on the principle of obtaining opposing images of a test object containing many point targets. The method is automatic in the sense that the centre of rotation is cal...

journal_title：Physics in medicine and biology

authors： Jago JR

更新日期：1994-12-01 00:00:00

abstract：:We report on a set of cell survival experiments performed in complex field combinations of therapeutic 12C ion beams. CHO cells were exposed to the superposition of two or three fields of 12C ions arranged in a similar way to real patient treatments. Two-dimensional survival distributions were measured and compared wi...

journal_title：Physics in medicine and biology

authors： Krämer M,Wang JF,Weyrather W

更新日期：2003-07-21 00:00:00

abstract：:Intra-fractional motion is a concern during prostate radiation therapy, as it may cause deviations between planned and delivered radiation doses. Because accurate motion information during treatment delivery is critical to address dose deviation, we developed the projection marker matching method (PM3), a novel method...

journal_title：Physics in medicine and biology

authors： Chi Y,Rezaeian NH,Shen C,Zhou Y,Lu W,Yang M,Hannan R,Jia X

更新日期：2017-07-07 00:00:00

abstract：:Awake and/or freely moving small animal single photon emission imaging allows the continuous study of molecules exhibiting slow kinetics without the need to restrain or anaesthetise the animals. Estimating motion free projections in freely moving small animal planar imaging can be considered as a limited angle tomogra...

journal_title：Physics in medicine and biology

authors： Angelis GI,Ryder WJ,Gillam JE,Boisson F,Kyme AZ,Fulton RR,Meikle SR,Kench PL

更新日期：2017-05-21 00:00:00

abstract：:Plutonium-239 and americium-241 were administered to adult hamsters in various chemical forms and their absorption from the gut was measured. The results have been compared with published data on other species in order to derive values for the estimated absorption of these actinides in man. On the basis of current kno...

journal_title：Physics in medicine and biology

authors： Stather JW,Harrison JD,Rodwell P,David AJ

更新日期：1979-03-01 00:00:00

abstract：:Respiratory gating based on external surrogates is performed in many clinics. We have developed a new technique for treatment verification using an electronic portal imaging device (EPID) in cine mode for gated 3D conformal therapy. Implanted radiopaque fiducial markers inside or near the target are required for this ...

journal_title：Physics in medicine and biology

authors： Berbeco RI,Neicu T,Rietzel E,Chen GT,Jiang SB

更新日期：2005-08-21 00:00:00

abstract：:Radiochromic leuco crystal violet (LCV) micelle gel dosimeters are promising three-dimensional radiation dosimeters because of their spatial stability and suitability for optical readout. The effects of surfactant type and surfactant concentration on dose sensitivity of LCV micelle gels are tested, demonstrating that ...

journal_title：Physics in medicine and biology

authors： Nasr AT,Alexander K,Schreiner LJ,McAuley KB

更新日期：2015-06-21 00:00:00

abstract：:Our aim is to investigate the impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging using a population of patient respiratory traces. A total of 1295 respiratory traces acquired during whole body PET/CT imaging were classified into three types according to the qualitative shape ...

journal_title：Physics in medicine and biology

authors： Liu C,Pierce LA 2nd,Alessio AM,Kinahan PE

更新日期：2009-12-21 00:00:00

abstract：:The reference levels for testing compliance of human exposure with radio-frequency (RF) safety limits have been derived from very simplified models of the human. In order to validate these findings for anatomical models, we investigated the absorption characteristics for various anatomies ranging from 6 year old child...

journal_title：Physics in medicine and biology

authors： Kühn S,Jennings W,Christ A,Kuster N

更新日期：2009-02-21 00:00:00

abstract：:A cost-effective method employing polysulphone, nalidixic acid, 8-methoxypsoralen and phenothiazine as UV dosimeters is presented for evaluating the UV spectrum. The exposure measured by each dosimeter is a function of the source spectrum and the spectral response of the material. Each material has a different spectra...

journal_title：Physics in medicine and biology

authors： Parisi AV,Wong JC,Moore GI

更新日期：1997-01-01 00:00:00

abstract：:For PET online data acquisition, a centralized coincidence processor (CCP) with a single-thread data processing has been used to select coincidence events for many PET scanners. CCP has the advantage of highly integrated circuit, compact connection between detector front-end and system electronics, and centralized con...

journal_title：Physics in medicine and biology

authors： Cheng X,Hu K,Yang D,Shao Y

更新日期：2021-01-21 00:00:00

abstract：:A hybrid proportional-integral-in-time and cost-minimizing-in-space feedback control system for electromagnetic, deep regional hyperthermia is proposed. The unique features of this controller are that (1) it uses temperature, not specific absorption rate, as the criterion for selecting the relative phases and amplitud...

journal_title：Physics in medicine and biology

authors： Kowalski ME,Jin JM

更新日期：2003-03-07 00:00:00

abstract：:Proton, as well as other ion, beams applied by electro-magnetic deflection in pencil-beam scanning (PBS) are minimally perturbed and thus can be quantified a priori by their fundamental interactions in a medium. This a priori quantification permits an optimal reduction of characterizing measurements on a particular PB...

journal_title：Physics in medicine and biology

authors： Clasie B,Depauw N,Fransen M,Gomà C,Panahandeh HR,Seco J,Flanz JB,Kooy HM

更新日期：2012-03-07 00:00:00

abstract：:Radiotherapy treatment planning relies on the use of geometrically correct images. This paper presents a fully automatic tool for correcting MR images for the effects of B(0) inhomogeneities. The post-processing method is based on the gradient-reversal technique of Chang and Fitzpatrick (1992 IEEE Trans. Med. Imaging ...

journal_title：Physics in medicine and biology

authors： Reinsberg SA,Doran SJ,Charles-Edwards EM,Leach MO

更新日期：2005-06-07 00:00:00

abstract：:Planning of radiotherapy is often difficult due to restrictions on morphological images. New imaging techniques enable the integration of biological information into treatment planning and help to improve the detection of vital and aggressive tumour areas. This might improve clinical outcome. However, nowadays morphol...

journal_title：Physics in medicine and biology

authors： Neff T,Kiessling F,Brix G,Baudendistel K,Zechmann C,Giesel FL,Bendl R

更新日期：2005-09-07 00:00:00

abstract：:In this study, an induced electric field in a human body is evaluated for the magnetic field leaked from a wireless power transfer system for charging an electrical vehicle. The magnetic field from the wireless power transfer system is modelled computationally, and its effectiveness is confirmed by comparison with the...

journal_title：Physics in medicine and biology

authors： Laakso I,Hirata A

更新日期：2013-11-07 00:00:00

abstract：:The Akaike information criterion and the associated Akaike weights (AW) rank pharmacokinetic models on the basis of goodness-of-fit and number of parameters. The usefulness of this information for improving the haemodynamic parameter estimates from DCE-MRI was investigated through two examples. In each of these, the e...

journal_title：Physics in medicine and biology

authors： Luypaert R,Ingrisch M,Sourbron S,de Mey J

更新日期：2012-06-07 00:00:00

abstract：:The stochastic nature of cavitation implies visualization of the cavitation cloud in real-time and in a discriminative manner for the safe use of focused ultrasound therapy. This visualization is sometimes possible with standard echography, but it strongly depends on the quality of the scanner, and is hindered by diff...

journal_title：Physics in medicine and biology

authors： Arnal B,Baranger J,Demene C,Tanter M,Pernot M

更新日期：2017-02-07 00:00:00

abstract：:The goal of this study was to assess the impact of set-up uncertainty on compliance with the objectives and constraints of an intensity modulated radiation therapy protocol for early stage cancer of the oropharynx. As the convolution approach to the quantitative study of set-up uncertainties cannot accommodate either ...

journal_title：Physics in medicine and biology

authors： Ploquin N,Song W,Lau H,Dunscombe P

更新日期：2005-08-07 00:00:00

abstract：:Ultrasoft x-rays of 0.3-5 keV have provided a unique tool for the investigation of intracellular mechanisms of radiation action in biological organisms, including mammalian cells. However, their use presents unique practical problems in dosimetry and experimental design. Detailed interpretation of the biological resul...

journal_title：Physics in medicine and biology

authors： Hoshi M,Goodhead DT,Brenner DJ,Bance DA,Chmielewski JJ,Paciotti MA,Bradbury JN

更新日期：1985-10-01 00:00:00

abstract：:This paper presents a Fourier rebinning algorithm for three-dimensional image reconstruction in PET that incorporates the concept of spectral transfer function. It suggests the need for discarding low-frequency components in the rebinning. It also includes the correction for rebinning efficiency which was evaluated by...

journal_title：Physics in medicine and biology

authors： Tanaka E,Amo Y

更新日期：1998-04-01 00:00:00

abstract：:The bone suppression technique based on advanced image processing can suppress the conspicuity of bones on chest radiographs, creating soft tissue images obtained by the dual-energy subtraction technique. This study was performed to evaluate the usefulness of bone suppression image processing in image-guided radiation...

journal_title：Physics in medicine and biology

authors： Tanaka R,Sanada S,Sakuta K,Kawashima H

更新日期：2015-05-21 00:00:00

abstract：:Digital phantoms continue to play a significant role in modeling and characterizing medical imaging. The currently available XCAT phantom incorporates both the flexibility of mathematical phantoms and the realistic nature of voxelized phantoms. This phantom generates images based on a regular breathing pattern and can...

journal_title：Physics in medicine and biology

authors： Mishra P,St James S,Segars WP,Berbeco RI,Lewis JH

更新日期：2012-06-07 00:00:00

abstract：:In this study, we evaluate the feasibility of designing a beveled fiber-optic probe coupled with a ball lens for improving depth-resolved fluorescence measurements of epithelial tissue using Monte Carlo (MC) simulations. The results show that by using the probe configuration with a beveled tip collection fiber and a f...

journal_title：Physics in medicine and biology

authors： Jaillon F,Zheng W,Huang Z

更新日期：2008-02-21 00:00:00

abstract：:Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome...

journal_title：Physics in medicine and biology

authors： Holbrook M,Clark DP,Badea CT

更新日期：2018-01-09 00:00:00

abstract：:Measurement of total body nitrogen is assuming increasing importance in the nutritional evaluation of seriously ill patients. Nitrogen has been previously measured either by counting (i) the annihilation radiation from 13N immediately after neutron irradiation with 14 MeV neutrons or (ii) the 'prompt' gamma rays from ...

journal_title：Physics in medicine and biology

authors： Spinks TJ,Goode AW,Ranicar AS,Steere E

更新日期：1984-04-01 00:00:00