Recent experimental results on W-values for heavy particles.

abstract：:Breast-conserving surgery is a standard option for the treatment of patients with early-stage breast cancer. This form of surgery may result in incomplete excision of the tumor. Iodine-125 labeled titanium seeds are currently used in clinical practice to reduce the number of incomplete excisions. It seems likely that ...

journal_title：Physics in medicine and biology

authors： Arsenali B,de Jong HW,Viergever MA,Dickerscheid DB,Beijst C,Gilhuijs KG

更新日期：2015-10-07 00:00:00

abstract：:Using Monte Carlo simulation of 99Tcm single-photon-emission computed tomography (SPECT), we investigate the effects of tissue-background activity, tumour location, patient size, uncertainty of energy windows, and definition of tumour region on the accuracy of quantification. The dual-energy-window method of correctio...

journal_title：Physics in medicine and biology

authors： Luo JQ,Koral KF,Ljungberg M,Floyd CE Jr,Jaszczak RJ

更新日期：1995-01-01 00:00:00

abstract：:Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. If the actual time range of activity of sources is significantly shorter than the time range being analysed, the detectability, localization and time-course de...

journal_title：Physics in medicine and biology

authors： Jun SC,George JS,Plis SM,Ranken DM,Schmidt DM,Wood CC

更新日期：2006-05-21 00:00:00

abstract：:K-edge subtraction (KES) imaging is a technique able to map a specific element such as e.g. a contrast agent within the tissues, by exploiting the sharp rise of its absorption coefficient at the K-edge energy. Whereas mainly explored at synchrotron radiation sources, the energy discrimination properties of modern x-ra...

journal_title：Physics in medicine and biology

authors： Brun F,Di Trapani V,Albers J,Sacco P,Dreossi D,Brombal L,Rigon L,Longo R,Mittone A,Dullin C,Bravin A,Delogu P

更新日期：2020-03-06 00:00:00

abstract：:Lung tumors treated in breath-hold are subject to inter- and intra-breath-hold variations, which makes tumor position monitoring during each breath-hold important. A markerless technique is desirable, but limited tumor visibility on kV images makes this challenging. We evaluated if template matching  +  triangulation ...

journal_title：Physics in medicine and biology

authors： Hazelaar C,Dahele M,Mostafavi H,van der Weide L,Slotman B,Verbakel W

更新日期：2018-05-29 00:00:00

abstract：:Deep learning models are highly parameterized, resulting in difficulty in inference and transfer learning for image recognition tasks. In this work, we propose a layered pathway evolution method to compress a deep convolutional neural network (DCNN) for classification of masses in digital breast tomosynthesis (DBT). T...

journal_title：Physics in medicine and biology

authors： Samala RK,Chan HP,Hadjiiski LM,Helvie MA,Richter C,Cha K

更新日期：2018-05-01 00:00:00

abstract：:The variety of treatment options for cancer patients has increased significantly in recent years. Not only do we combine radiation with surgery and chemotherapy, new therapeutic approaches such as immunotherapy and targeted therapies are starting to play a bigger role. Physics has made significant contributions to rad...

journal_title：Physics in medicine and biology

authors： Grassberger C,Paganetti H

更新日期：2016-11-07 00:00:00

abstract：:Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography applications such as computed tomography (CT), the water-equival...

journal_title：Physics in medicine and biology

authors： Poludniowski G,Allinson NM,Anaxagoras T,Esposito M,Green S,Manolopoulos S,Nieto-Camero J,Parker DJ,Price T,Evans PM

更新日期：2014-06-07 00:00:00

abstract：:The diagnosis of hepatocellular carcinoma (HCC) usually occurs at late stages in the disease when there are few effective treatment options. The measurement of the concentration of tumour markers in the serum of patients is a complementary tool frequently used for the interpretation of diagnostic imaging results. It i...

journal_title：Physics in medicine and biology

authors： Elshemey WM,Desouky OS,Mohammed MS,Elsayed AA,el-Houseini ME

更新日期：2003-09-07 00:00:00

abstract：:DMSA imaging is carried out in nuclear medicine to assess the level of functional renal tissue in patients. This study investigated the use of an artificial neural network to perform diagnostic classification of these scans. Using the radiological report as the gold standard, the network was trained to classify DMSA s...

journal_title：Physics in medicine and biology

authors： Wright JW,Duguid R,McKiddie F,Staff RT

更新日期：2014-04-07 00:00:00

abstract：:Using MRI for radiotherapy treatment planning and image guidance is appealing as it provides superior soft tissue information over CT scans and avoids possible systematic errors introduced by aligning MR to CT images. This study presents a method that generates Synthetic CT (MRCT) volumes by performing probabilistic t...

journal_title：Physics in medicine and biology

authors： Liu L,Jolly S,Cao Y,Vineberg K,Fessler JA,Balter JM

更新日期：2017-04-21 00:00:00

abstract：:Characterization of both malignant and benign lesions in the female breast is presented as the result of a clinical study that involved more than 190 subjects in the framework of the OPTIMAMM European project. All the subjects underwent optical mammography, by means of a multi-wavelength time-resolved mammograph, in t...

journal_title：Physics in medicine and biology

authors： Spinelli L,Torricelli A,Pifferi A,Taroni P,Danesini G,Cubeddu R

更新日期：2005-06-07 00:00:00

abstract：:In brachytherapy, plans are routinely calculated using the AAPM TG43 formalism which considers the patient as a simple water object. An accurate modeling of the physical processes considering patient heterogeneity using Monte Carlo simulation (MCS) methods is currently too time-consuming and computationally demanding ...

journal_title：Physics in medicine and biology

authors： Lemaréchal Y,Bert J,Falconnet C,Després P,Valeri A,Schick U,Pradier O,Garcia MP,Boussion N,Visvikis D

更新日期：2015-07-07 00:00:00

abstract：:By means of the viscoelastodynamic model for a two-layer solid-fluid system and a detailed account of the locally induced acoustic radiation force, a rational analytical and computational framework is established for the viscoelastic characterization of thin tissues from high-frequency ultrasound (HFUS) measurements. ...

journal_title：Physics in medicine and biology

authors： Guzina BB,Tuleubekov K,Liu D,Ebbini ES

更新日期：2009-07-07 00:00:00

abstract：:In this paper we present a novel method of reducing the dosimetric effects of the finite leaf width of a multileaf collimator (MLC) in conformal and intensity modulated radiotherapy (IMRT). This is achieved by decomposing the required high-resolution fluence distribution into two orthogonal components, which are deliv...

journal_title：Physics in medicine and biology

authors： Evans PM,Partridge M

更新日期：2000-03-01 00:00:00

abstract：:Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

journal_title：Physics in medicine and biology

authors： Younis AR,Watt DE

更新日期：1989-07-01 00:00:00

abstract：:The sensitivity and detection limit for measurements of the concentration of cadmium in the kidney cortex of man in vivo have been investigated using the technique of X-ray fluorescence. An 11 GB1 241Am source was used to generate the characteristic K alpha X-rays of cadmium. The variation in the sensitivity for the d...

journal_title：Physics in medicine and biology

authors： Ahlgren L,Mattsson S

更新日期：1981-01-01 00:00:00

abstract：:This paper analyzes the radio frequencies (RF) exposure in the head tissues of children using a cellular handset or RF sources (a dipole and a generic handset) at 900, 1800, 2100 and 2400 MHz. Based on magnetic resonance imaging, child head models have been developed. The maximum specific absorption rate (SAR) over 10...

journal_title：Physics in medicine and biology

authors： Wiart J,Hadjem A,Wong MF,Bloch I

更新日期：2008-07-07 00:00:00

abstract：:Using Cherenkov radiation in positron emission tomography (PET) has the potential to improve the time of flight (TOF) resolution and reduce the cost of detectors. In previous studies promising TOF results were achieved when lead fluoride (PbF2) crystals were used instead of a scintillator. In this work, a whole-body P...

journal_title：Physics in medicine and biology

authors： Consuegra D,Korpar S,Križan P,Pestotnik R,Razdevšek G,Dolenec R

更新日期：2020-03-06 00:00:00

abstract：:The purpose of this research is to develop a 4DCBCT-based dose assessment method for calculating actual delivered dose for patients with significant respiratory motion or anatomical changes during the course of SBRT. To address the limitation of 4DCT-based dose assessment, we propose to calculate the delivered dose us...

journal_title：Physics in medicine and biology

authors： Cai W,Dhou S,Cifter F,Myronakis M,Hurwitz MH,Williams CL,Berbeco RI,Seco J,Lewis JH

更新日期：2016-01-21 00:00:00

abstract：:The results of optimization of inverse treatment plans depend on a choice of the objective function. Even when the optimal solution for a given cost function can be obtained, a better solution may exist for a given clinical scenario and it could be obtained with a revised objective function. In the approach presented ...

journal_title：Physics in medicine and biology

authors： Bednarz G,Michalski D,Anne PR,Valicenti RK

更新日期：2004-06-21 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is an effective procedure for patients with heart failure but 30% of patients do not respond. This may be due to sub-optimal placement of the left ventricular (LV) lead. It is hypothesized that the use of cardiac anatomy, myocardial scar distribution and dyssynchrony information...

journal_title：Physics in medicine and biology

authors： Ma YL,Shetty AK,Duckett S,Etyngier P,Gijsbers G,Bullens R,Schaeffter T,Razavi R,Rinaldi CA,Rhode KS

更新日期：2012-05-21 00:00:00

abstract：:Light propagation in a turbid medium is considered using the linear transport equation. The existence of a diffusion length is proved for the Henyey-Greenstein scattering kernel for all absorption ratios. Numerical methods are given that allow accurate computation of the diffusion coefficient quite easily. ...

journal_title：Physics in medicine and biology

authors： Sahni DC,Dahl EB,Sjöstrand NG

更新日期：2003-12-07 00:00:00

abstract：:Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

journal_title：Physics in medicine and biology

authors： Wong JT,Molloi S

更新日期：2008-07-21 00:00:00

abstract：:The purpose of this study is to develop a new global mammographic image feature analysis based computer-aided detection (CAD) scheme and evaluate its performance in detecting positive screening mammography examinations. A dataset that includes images acquired from 1896 full-field digital mammography (FFDM) screening e...

journal_title：Physics in medicine and biology

authors： Tan M,Qian W,Pu J,Liu H,Zheng B

更新日期：2015-06-07 00:00:00

abstract：:Evidence that some lung tumors change shape during respiration is derived from respiratory gated CT data by statistical shape modeling and image manipulation. Some tumors behave as rigid objects while others show systematic shape changes. Two views of lung motion are presented to allow analysis of the results. In the ...

journal_title：Physics in medicine and biology

authors： Kyriakou E,McKenzie DR

更新日期：2012-02-21 00:00:00

abstract：:Nuclear medicine and radiation therapy, although well established, are still rapidly evolving, by exploiting animal models, aiming to define precise dosimetry in molecular imaging protocols. The purpose of the present study was to create a dataset based on the MOBY phantom for the calculation of organ-to-organ S-value...

journal_title：Physics in medicine and biology

authors： Kostou T,Papadimitroulas P,Loudos G,Kagadis GC

更新日期：2016-03-21 00:00:00

abstract：:The goal of this study was to determine the quantitative accuracy of our OSEM-APDI reconstruction method based on SPECT/CT imaging for Tc-99m, In-111, I-123, and I-131 isotopes. Phantom studies were performed on a SPECT/low-dose multislice CT system (Infinia-Hawkeye-4 slice, GE Healthcare) using clinical acquisition p...

journal_title：Physics in medicine and biology

authors： Shcherbinin S,Celler A,Belhocine T,Vanderwerf R,Driedger A

更新日期：2008-09-07 00:00:00

abstract：:An iterative Bayesian reconstruction algorithm for limited view angle tomography, or ectomography, based on the three-dimensional total variation (TV) norm has been developed. The TV norm has been described in the literature as a method for reducing noise in two-dimensional images while preserving edges, without intro...

journal_title：Physics in medicine and biology

authors： Persson M,Bone D,Elmqvist H

更新日期：2001-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the impact of numerical errors caused by the floating point representation of real numbers in a GPU-based Monte Carlo code used for dose calculation in radiation oncology, and to identify situations where this type of error arises. The program used as a benchmark was bGPUMCD. ...

journal_title：Physics in medicine and biology

authors： Magnoux V,Ozell B,Bonenfant É,Després P

更新日期：2015-07-07 00:00:00