An experimental evaluation of the Agility MLC for motion-compensated VMAT delivery.

abstract：:The purpose of this work is to develop and test a method to estimate the relative and absolute absorbed radiation dose from axial and spiral CT scans using a Monte Carlo approach. Initial testing was done in phantoms and preliminary results were obtained from a standard mathematical anthropomorphic model (MIRD V) and ...

journal_title：Physics in medicine and biology

authors： Jarry G,DeMarco JJ,Beifuss U,Cagnon CH,McNitt-Gray MF

更新日期：2003-08-21 00:00:00

abstract：:In this paper we describe a method for quantitative photoacoustic tomography (qPAT) based on the photon radiative transfer equation (RTE) coupled with the Helmholtz photoacoustic wave equation. Considerable simulations and tissue-like phantom experiments are conducted to evaluate transport-based qPAT in comparison wit...

journal_title：Physics in medicine and biology

authors： Yao L,Sun Y,Jiang H

更新日期：2010-04-07 00:00:00

abstract：:We experimentally investigated the SPECT recovery of I-131 activity in multiple spheres located simultaneously at different locations within a cylindrical phantom that had an elliptical cross section. The sphere volumes ranged from 209 cc down to 4.2 cc. A Prism 3000 camera and two types of parallel-hexagonal-hole col...

journal_title：Physics in medicine and biology

authors： Koral KF,Yendiki A,Dewaraja YK

更新日期：2007-02-07 00:00:00

abstract：:For the first time, three-dimensional images of the newborn infant brain have been generated using measurements of transmitted light. A 32-channel time-resolved imaging system was employed, and data were acquired using custom-made helmets which couple source fibres and detector bundles to the infant head. Images have ...

journal_title：Physics in medicine and biology

authors： Hebden JC,Gibson A,Yusof RM,Everdell N,Hillman EM,Delpy DT,Arridge SR,Austin T,Meek JH,Wyatt JS

更新日期：2002-12-07 00:00:00

abstract：:The purpose of this study was to derive a complete set of correction and perturbation factors for output factors (OF) and dose profiles. Modern small field detectors were investigated including a plastic scintillator (Exradin W1, SI), a liquid ionization chamber (microLion 31018, PTW), an unshielded diode (Exradin D1V...

journal_title：Physics in medicine and biology

authors： Papaconstadopoulos P,Tessier F,Seuntjens J

更新日期：2014-10-07 00:00:00

abstract：:A 3D anatomical computational model is developed to assess thermal effects due to exposure to the electromagnetic field required to power a new investigational active implantable microvalve for the treatment of glaucoma. Such a device, located in the temporal superior eye quadrant, produces a filtering bleb, which is ...

journal_title：Physics in medicine and biology

authors： Schaumburg F,Guarnieri FA

更新日期：2017-05-07 00:00:00

abstract：:Current dosimetry protocols recommend the use of plane-parallel ionization chambers for the dosimetry of clinical electron beams. The necessary perturbation corrections p(wall) and p(cav) are assumed to be unity, independent of the depth of measurement and the energy of the primary electrons. To verify these assumptio...

journal_title：Physics in medicine and biology

authors： Zink K,Wulff J

更新日期：2009-04-21 00:00:00

abstract：:In the IAEA TRS-381 protocol, k(cel) and p(cel) account for the central electrode perturbation during the air kerma chamber calibration and the in-phantom measurements. The values of these correction factors are based mainly on Monte Carlo simulations. In the present work experimental data on k(cel) and p(cel) for the...

journal_title：Physics in medicine and biology

authors： Palm A,Mattsson O

更新日期：1999-05-01 00:00:00

abstract：:Source anisotropy is a very important factor in the brachytherapy quality assurance of high-dose rate (HDR) 192Ir afterloading stepping sources. If anisotropy is not taken into account then doses received by a brachytherapy patient in certain directions can be in error by a clinically significant amount. Experimental ...

journal_title：Physics in medicine and biology

authors： Baltas D,Giannouli S,Garbi A,Diakonos F,Geramani K,Ioannidis GT,Tsalpatouros A,Uzunoglu N,Kolotas C,Zamboglou N

更新日期：1998-06-01 00:00:00

abstract：:Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality of any automatic registration procedure has been a challenging part because no gold standard is available to e...

journal_title：Physics in medicine and biology

authors： Ceylan C,van der Heide UA,Bol GH,Lagendijk JJ,Kotte AN

更新日期：2005-05-21 00:00:00

abstract：:We show that it is possible to translate an intensity modulated radiation therapy (IMRT) treatment plan and deliver it as a single arc. This technique is referred to in this paper as aperture modulation arc therapy (AMAT). During this arc, the MLC leaves do not conform to the projection of the target PTV and the machi...

journal_title：Physics in medicine and biology

authors： Crooks SM,Wu X,Takita C,Watzich M,Xing L

更新日期：2003-05-21 00:00:00

abstract：:Energy and spatial projection distributions were simulated for gamma camera imaging of multiple order Compton scattered photons. SPECT imaging of a line source of radioactivity located in a water filled cylindrical phantom was modelled using Monte Carlo techniques. Photon trajectories were followed from emission to de...

journal_title：Physics in medicine and biology

authors： Floyd CE,Jaszczak RJ,Harris CC,Coleman RE

更新日期：1984-10-01 00:00:00

abstract：:Tserng and Kalhan have raised the question of the appropriate equation to use for the measurement of turnover rate in a stable-isotope study. In a comparison of glucose turnover measured with 2H-glucose and with 13C-glucose they used five apparently different equations and obtained conflicting answers. There is, howev...

journal_title：Physics in medicine and biology

authors： Wootton R,Ford GC,Cheng KN,Halliday D

更新日期：1985-10-01 00:00:00

abstract：:We present a novel linear programming (LP) based approach for efficiently solving the intensity modulated radiation therapy (IMRT) fluence-map optimization (FMO) problem to global optimality. Our model overcomes the apparent limitations of a linear-programming approach by approximating any convex objective function by...

journal_title：Physics in medicine and biology

authors： Romeijn HE,Ahuja RK,Dempsey JF,Kumar A,Li JG

更新日期：2003-11-07 00:00:00

abstract：:The spatial resolution of 2D detector arrays equipped with ionization chambers or diodes, used for the dose verification of IMRT treatment plans, is limited by the size of the single detector and the centre-to-centre distance between the detectors. Optimization criteria with regard to these parameters have been develo...

journal_title：Physics in medicine and biology

authors： Poppe B,Djouguela A,Blechschmidt A,Willborn K,Rühmann A,Harder D

更新日期：2007-05-21 00:00:00

abstract：:Intensity-modulated radiation therapy (IMRT) can be delivered by the 'sliding-leaves' dynamic multileaf collimator (DMLC) technique. Intrafraction organ motion can be accommodated by arranging an identical tracking motion for 'breathing leaves'. However, this is only possible for very specific circumstances such as re...

journal_title：Physics in medicine and biology

authors： Webb S,Binnie DM

更新日期：2006-09-21 00:00:00

abstract：:Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

journal_title：Physics in medicine and biology

authors： Li Y,Matej S,Karp JS,Metzler SD

更新日期：2015-01-21 00:00:00

abstract：:Optical topography is a method for visualization of conical activity. Ways of improving the spatial resolution of the topographical image with three arrangements of optical fibres are discussed. A distribution of sensitivity is obtained from the phantom experiment, and used to reconstruct topographical images of an ac...

journal_title：Physics in medicine and biology

authors： Yamamoto T,Maki A,Kadoya T,Tanikawa Y,Yamad Y,Okada E,Koizumi H

更新日期：2002-09-21 00:00:00

abstract：:Scatter correction is an essential technique to improve the image quality of cone-beam CT (CBCT). Although different scatter correction methods have been proposed in the literature, a standard solution is still being studied due to the limitations including accuracy, computation efficiency and generalization. In this ...

journal_title：Physics in medicine and biology

authors： Jiang Y,Yang C,Yang P,Hu X,Luo C,Xue Y,Xu L,Hu X,Zhang L,Wang J,Sheng K,Niu T

更新日期：2019-07-11 00:00:00

abstract：:Prenatal events such as intrauterine growth restriction and increased cardiovascular risk in later life have been shown to be associated with an increased intima-media thickness (aIMT) of the abdominal aorta in the fetus. In order to assess and manage atherosclerosis and cardiovascular disease risk in adults and child...

journal_title：Physics in medicine and biology

authors： Veronese E,Tarroni G,Visentin S,Cosmi E,Linguraru MG,Grisan E

更新日期：2014-11-07 00:00:00

abstract：:In previous work we demonstrated the potential of positron emission tomography (PET) detectors with depth-of-interaction (DOI) encoding capability based on phosphor-coated crystals. A DOI resolution of 8 mm full-width at half-maximum was obtained for 20 mm long scintillator crystals using a delayed charge integration ...

journal_title：Physics in medicine and biology

authors： Roncali E,Phipps JE,Marcu L,Cherry SR

更新日期：2012-10-21 00:00:00

abstract：:Picking geometrically relevant atlases from the whole training set is crucial to multi-atlas based image segmentation, especially with extensive data of heterogeneous quality in the Big Data era. Unfortunately, there is very limited understanding of how currently used image similarity criteria reveal geometric relevan...

journal_title：Physics in medicine and biology

authors： Zhao T,Ruan D

更新日期：2016-06-07 00:00:00

abstract：:The diagnosis of hepatocellular carcinoma (HCC) usually occurs at late stages in the disease when there are few effective treatment options. The measurement of the concentration of tumour markers in the serum of patients is a complementary tool frequently used for the interpretation of diagnostic imaging results. It i...

journal_title：Physics in medicine and biology

authors： Elshemey WM,Desouky OS,Mohammed MS,Elsayed AA,el-Houseini ME

更新日期：2003-09-07 00:00:00

abstract：:The enormous advances in the understanding of human anatomy, physiology and pathology in recent decades have led to ever-improving methods of disease prevention, diagnosis and treatment. Many of these achievements have been enabled, at least in part, by advances in ionizing radiation detectors. Radiology has been tran...

journal_title：Physics in medicine and biology

authors： Seco J,Clasie B,Partridge M

更新日期：2014-10-21 00:00:00

abstract：:Detailed studies of the basic contrast mechanisms in computerized transverse axial tomography scanners have been carried out. Contrast is related to the effective atomic numbers and electron densities of materials and the resultant linear attenuation coefficients. We have therefore quantitatively evaluated various sam...

journal_title：Physics in medicine and biology

authors： Tsai CM,Cho ZH

更新日期：1976-07-01 00:00:00

abstract：:Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted from pre-treatment diffusion-weighted magnetic resonance images (DWIs) for predi...

journal_title：Physics in medicine and biology

authors： Fu J,Zhong X,Li N,Van Dams R,Lewis J,Sung K,Raldow AC,Jin J,Qi XS

更新日期：2020-04-02 00:00:00

abstract：:Prompt gamma (PG) imaging is widely investigated for spot-by-spot in vivo range verification for proton therapy. Previous studies pointed out that the accuracy of prompt gamma imaging is affected by the statistics (number of protons delivered per pencil beam) of the proton beams and the conformity between prompt gamma...

journal_title：Physics in medicine and biology

authors： Tian L,Landry G,Dedes G,Pinto M,Kamp F,Belka C,Parodi K

更新日期：2020-04-29 00:00:00

abstract：:Random coincidences can contribute substantially to the background in positron emission tomography (PET). Several estimation methods are being used for correcting them. The goal of this study was to investigate the validity of techniques for random coincidence estimation, with various low-energy thresholds (LETs). Sim...

journal_title：Physics in medicine and biology

authors： Torres-Espallardo I,Rafecas M,Spanoudaki V,McElroy DP,Ziegler SI

更新日期：2008-05-07 00:00:00

abstract：:The class of non-rigid registration methods proposed in the framework of PDE-constrained large deformation diffeomorphic metric mapping is a particularly interesting family of physically meaningful diffeomorphic registration methods. Inexact Gauss-Newton-Krylov optimization has shown an excellent numerical accuracy an...

journal_title：Physics in medicine and biology

authors： Hernandez M

更新日期：2019-01-07 00:00:00

abstract：:The aim of this work was to evaluate the accuracy of dose predicted in heterogeneous media by a pencil beam (PB), a collapsed cone (CC) and a Monte Carlo (MC) algorithm. For this purpose, a simple multi-layer phantom composed of Styrofoam and white polystyrene was irradiated with 10 x 10 cm2 as well as 20 x 20 cm2 ope...

journal_title：Physics in medicine and biology

authors： Krieger T,Sauer OA

更新日期：2005-03-07 00:00:00