Extraction of the respiratory signal from small-animal CT projections for a retrospective gating method.

Abstract:

:We propose a retrospective respiratory gating algorithm to generate dynamic CT studies. To this end, we compared three different methods of extracting the respiratory signal from the projections of small-animal cone-beam computed tomography (CBCT) scanners. Given a set of frames acquired from a certain axial angle, subtraction of their average image from each individual frame produces a set of difference images. Pixels in these images have positive or negative values (according to the respiratory phase) in those areas where there is lung movement. The respiratory signals were extracted by analysing the shape of the histogram of these difference images: we calculated the first four central and non-central moments. However, only odd-order moments produced the desired breathing signal, as the even-order moments lacked information about the phase. Each of these curves was compared to a reference signal recorded by means of a pneumatic pillow. Given the similar correlation coefficients yielded by all of them, we selected the mean to implement our retrospective protocol. Respiratory phase bins were separated, reconstructed independently and included in a dynamic sequence, suitable for cine playback. We validated our method in five adult rat studies by comparing profiles drawn across the diaphragm dome, with and without retrospective respiratory gating. Results showed a sharper transition in the gated reconstruction, with an average slope improvement of 60.7%.

journal_name

Phys Med Biol

authors

Chavarrías C,Vaquero JJ,Sisniega A,Rodríguez-Ruano A,Soto-Montenegro ML,García-Barreno P,Desco M

doi

10.1088/0031-9155/53/17/015

subject

Has Abstract

pub_date

2008-09-07 00:00:00

pages

4683-95

issue

17

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(08)76372-3

journal_volume

53

pub_type

杂志文章
  • On the dosimetric behaviour of photon dose calculation algorithms in the presence of simple geometric heterogeneities: comparison with Monte Carlo calculations.

    abstract::A comparative study was performed to reveal differences and relative figures of merit of seven different calculation algorithms for photon beams when applied to inhomogeneous media. The following algorithms were investigated: Varian Eclipse: the anisotropic analytical algorithm, and the pencil beam with modified Batho...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/5/011

    authors: Fogliata A,Vanetti E,Albers D,Brink C,Clivio A,Knöös T,Nicolini G,Cozzi L

    更新日期:2007-03-07 00:00:00

  • The production of positron emitters with millisecond half-life during helium beam radiotherapy.

    abstract::Therapy with helium ions is currently receiving significantly increasing interest because helium ions have a sharper penumbra than protons and undergo less fragmentation than carbon ions and thus require less complicated dose calculations. For any ion of interest in hadron therapy, the accuracy of dose delivery is lim...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab51c3

    authors: Ozoemelam I,van der Graaf E,Brandenburg S,Dendooven P

    更新日期:2019-12-05 00:00:00

  • SimDoseCT: dose reporting software based on Monte Carlo simulation for a 320 detector-row cone-beam CT scanner and ICRP computational adult phantoms.

    abstract::This study aims to develop and test software for assessing and reporting doses for standard patients undergoing computed tomography (CT) examinations in a 320 detector-row cone-beam scanner. The software, called SimDoseCT, is based on the Monte Carlo (MC) simulation code, which was developed to calculate organ doses a...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa77ea

    authors: Cros M,Joemai RMS,Geleijns J,Molina D,Salvadó M

    更新日期:2017-07-17 00:00:00

  • A low-count reconstruction algorithm for Compton-based prompt gamma imaging.

    abstract::The Compton camera is an imaging device which has been proposed to detect prompt gammas (PGs) produced by proton-nuclear interactions within tissue during proton beam irradiation. Compton-based PG imaging has been developed to verify proton ranges because PG rays, particularly characteristic ones, have strong correlat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aab737

    authors: Huang HM,Liu CC,Jan ML,Lee MW

    更新日期:2018-04-19 00:00:00

  • Comparison study of temporal regularization methods for fully 5D reconstruction of cardiac gated dynamic SPECT.

    abstract::Temporal regularization plays a critical role in cardiac gated dynamic SPECT reconstruction, of which the goal is to obtain an image sequence from a single acquisition which simultaneously shows both cardiac motion and tracer distribution change over the course of imaging (termed 5D). In our recent work, we explored t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/17/5523

    authors: Niu X,Yang Y,King MA

    更新日期:2012-09-07 00:00:00

  • Evaluation of radiochromic gel dosimetry and polymer gel dosimetry in a clinical dose verification.

    abstract::A quantitative comparison of two full three-dimensional (3D) gel dosimetry techniques was assessed in a clinical setting: radiochromic gel dosimetry with an in-house developed optical laser CT scanner and polymer gel dosimetry with magnetic resonance imaging (MRI). To benchmark both gel dosimeters, they were exposed t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/18/6241

    authors: Vandecasteele J,De Deene Y

    更新日期:2013-09-21 00:00:00

  • Measurement of flow velocity fields in small vessel-mimic phantoms and vessels of small animals using micro ultrasonic particle image velocimetry (micro-EPIV).

    abstract::Determining a multidimensional velocity field within microscale opaque fluid flows is needed in areas such as microfluidic devices, biofluid mechanics and hemodynamics research in animal studies. The ultrasonic particle image velocimetry (EchoPIV) technique is appropriate for measuring opaque flows by taking advantage...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/20/003

    authors: Qian M,Niu L,Wang Y,Jiang B,Jin Q,Jiang C,Zheng H

    更新日期:2010-10-21 00:00:00

  • Site-specific volumetric analysis of lung tumour motion.

    abstract::The treatment of lung cancer with radiation therapy is hindered by respiratory motion. Real-time adjustments to compensate for this motion are hampered by mechanical system latencies and imaging-rate restrictions. To better understand tumour motion behaviour for adaptive image-guided radiation therapy of lung cancer, ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/12/005

    authors: Pepin EW,Wu H,Sandison GA,Langer M,Shirato H

    更新日期:2010-06-21 00:00:00

  • Dark-field signal extraction in propagation-based phase-contrast imaging.

    abstract::A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real decrement to the imaginary part of the complex refractive index, the proposed metho...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abac9d

    authors: Gureyev TE,Paganin DM,Arhatari B,Taba ST,Lewis S,Brennan PC,Quiney HM

    更新日期:2020-11-17 00:00:00

  • Application of an M-line-based backprojected filtration algorithm to triple-cone-beam helical CT.

    abstract::To increase the scanning speed of cone-beam CT, a scanning configuration with three pairs of x-ray sources and panel detectors was proposed. In this paper, we apply the M-line-based backprojected filtration algorithm to this scanning configuration and propose a fast implementation for this algorithm. Compared with exi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/23/009

    authors: Zhao Y,Zhu Y,Zhang P

    更新日期:2010-12-07 00:00:00

  • Modelling of electron contamination in clinical photon beams for Monte Carlo dose calculation.

    abstract::The purpose of this work is to model electron contamination in clinical photon beams and to commission the source model using measured data for Monte Carlo treatment planning. In this work, a planar source is used to represent the contaminant electrons at a plane above the upper jaws. The source size depends on the di...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/12/013

    authors: Yang J,Li JS,Qin L,Xiong W,Ma CM

    更新日期:2004-06-21 00:00:00

  • The recombination correction for an ionisation chamber exposed to pulsed radiation in a 'swept beam' technique. I. Theory.

    abstract::The established theory for the collection efficiency of an ionisation chamber irradiated by a series of uniform short pulses is extended to the more complex case of irradiation in a pulsed and electromagnetically swept electron beam. The radial variation of exposure rate is assumed to be Gaussian with scale constant e...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/27/2/001

    authors: Boag JW

    更新日期:1982-02-01 00:00:00

  • Influence of anisotropic compartments on magnetic field and electric potential distributions generated by artificial current dipoles inside a torso phantom.

    abstract::The purpose of this study is the analysis of the influence of anisotropic conductivity on magnetic fields and electric potentials by means of phantom measurements. An artificial rotating current dipole was placed in the middle of an anisotropic skein arrangement in a torso phantom filled with saline solution. The sign...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/1/017

    authors: Liehr M,Haueisen J

    更新日期:2008-01-07 00:00:00

  • W value measurements for protons in tissue-equivalent gas and its constituent gases.

    abstract::Values of W (the mean energy required to create an ion pair when a charged particle is stopped in a gas) are needed in radiation dosimetry to convert ionisation chamber current readings to absorbed dose. For neutron dosimetry the most important W values are those for protons, and this paper describes absolute measurem...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/30/11/003

    authors: Thomas DJ,Burke M

    更新日期:1985-11-01 00:00:00

  • Comparison of in vivo scintillation probes and gamma cameras for detection of small, deep tumours.

    abstract::An in vivo probe was compared with a gamma camera for the task of detecting radiolabelled tumour models in a water phantom. The probe, which contained a 1 cm diameter NaI(T1) detector, was designed and used by us for surgical staging studies of gynaecological patients. Tumours were spherical sources of different sizes...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/34/6/008

    authors: Barber HB,Barrett HH,Woolfenden JM,Myers KJ,Hickernell TS

    更新日期:1989-06-01 00:00:00

  • Electron depth-dose dependence on energy spectral quality.

    abstract::Electron depth-dose curves and spectra have been measured from an experimental accelerator on which both energy and spectral shape could be varied independently. The measurements were made at nominal energies of 6 and 12 MeV, with the energy spread (FWHM) varied from 1.7% to over 10% of average energy. Changes in dept...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/28/12/005

    authors: Johnsen SW,LaRiviere PD,Tanabe E

    更新日期:1983-12-01 00:00:00

  • Evaluation of the induced electric field and compliance procedure for a wireless power transfer system in an electrical vehicle.

    abstract::In this study, an induced electric field in a human body is evaluated for the magnetic field leaked from a wireless power transfer system for charging an electrical vehicle. The magnetic field from the wireless power transfer system is modelled computationally, and its effectiveness is confirmed by comparison with the...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/21/7583

    authors: Laakso I,Hirata A

    更新日期:2013-11-07 00:00:00

  • Generalized method for computation of true thickness and x-ray intensity information in highly blurred sub-millimeter bone features in clinical CT images.

    abstract::In clinical computed tomography (CT) images, cortical bone features with sub-millimeter (sub-mm) thickness are substantially blurred, such that their thickness is overestimated and their intensity appears underestimated. Therefore, any inquiry of the geometry or the density of such bones based on these images is sever...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/23/8099

    authors: Pakdel A,Robert N,Fialkov J,Maloul A,Whyne C

    更新日期:2012-12-07 00:00:00

  • Automatic system for measuring dose-area product (DAP) in ROI fluoroscopy.

    abstract::A computerized system for monitoring dose-area product (DAP) has been developed for region of interest (ROI) fluoroscopy in which patient exposure is reduced using an x-ray attenuating filter with an aperture. The system includes an IBM compatible computer which is connected through an IEEE-488 interface to an electro...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/42/4/001

    authors: Kezerashvili M,Bednarek DR,Rudin S

    更新日期:1997-04-01 00:00:00

  • In-bore setup and software for 3T MRI-guided transperineal prostate biopsy.

    abstract::MRI-guided prostate biopsy in conventional closed-bore scanners requires transferring the patient outside the bore during needle insertion due to the constrained in-bore space, causing a safety hazard and limiting image feedback. To address this issue, we present our custom-made in-bore setup and software to support M...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/18/5823

    authors: Tokuda J,Tuncali K,Iordachita I,Song SE,Fedorov A,Oguro S,Lasso A,Fennessy FM,Tempany CM,Hata N

    更新日期:2012-09-21 00:00:00

  • The noise navigator: a surrogate for respiratory-correlated 4D-MRI for motion characterization in radiotherapy.

    abstract::Respiratory-correlated 4D-MRI can characterize respiratory-induced motion of tumors and organs-at-risk for radiotherapy treatment planning and is a necessity for image guidance of moving tumors treated on an MRI-linac. Essential for 4D-MRI generation is a robust respiratory surrogate signal. We investigated the feasib...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab5c62

    authors: Navest RJM,Mandija S,Bruijnen T,Stemkens B,Tijssen RHN,Andreychenko A,Lagendijk JJW,van den Berg CAT

    更新日期:2020-01-13 00:00:00

  • Fuzzy clustering-based segmented attenuation correction in whole-body PET imaging.

    abstract::Segmented attenuation correction is now a widely accepted technique to reduce noise propagation from transmission scanning in positron emission tomography (PET). In this paper, we present a new method for segmenting transmission images in whole-body scanning. This reduces the noise in the correction maps while still c...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/7/310

    authors: Zaidi H,Diaz-Gomez M,Boudraa A,Slosman DO

    更新日期:2002-04-07 00:00:00

  • Convex reformulation of biologically-based multi-criteria intensity-modulated radiation therapy optimization including fractionation effects.

    abstract::Finding fluence maps for intensity-modulated radiation therapy (IMRT) can be formulated as a multi-criteria optimization problem for which Pareto optimal treatment plans exist. To account for the dose-per-fraction effect of fractionated IMRT, it is desirable to exploit radiobiological treatment plan evaluation criteri...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/22/006

    authors: Hoffmann AL,den Hertog D,Siem AY,Kaanders JH,Huizenga H

    更新日期:2008-11-21 00:00:00

  • A theoretical comparison of energy sources--microwave, ultrasound and laser--for interstitial thermal therapy.

    abstract::A number of heating sources are available for minimally invasive thermal therapy of tumours. The purpose of this work was to compare, theoretically, the heating characteristics of interstitial microwave, laser and ultrasound sources in three tissue sites: breast, brain and liver. Using a numerical method, the heating ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/12/011

    authors: Skinner MG,Iizuka MN,Kolios MC,Sherar MD

    更新日期:1998-12-01 00:00:00

  • Computational dosimetry in embryos exposed to electromagnetic plane waves over the frequency range of 10 MHz-1.5 GHz.

    abstract::This paper presents calculated specific absorption rate (SAR) dosimetry in 4 and 8 week Japanese pregnant-woman models exposed to plane waves over the frequency range of 10 MHz-1.5 GHz. Two types of 2 mm spatial-resolution pregnant-woman models comprised a woman model, which is similar to the average-sized Japanese ad...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/1/N01

    authors: Kawai H,Nagaoka T,Watanabe S,Saito K,Takahashi M,Ito K

    更新日期:2010-01-07 00:00:00

  • Calibration of CT Hounsfield units for radiotherapy treatment planning of patients with metallic hip prostheses: the use of the extended CT-scale.

    abstract::Heterogeneity corrections for radiotherapy dose calculations are based on the electron density of the disturbing heterogeneity. However, when CT planning a radiotherapy treatment, where metallic hip implants are present, considerable artefacts are seen in the images. Often, an additional problem arises whereby no info...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/48/11/308

    authors: Coolens C,Childs PJ

    更新日期:2003-06-07 00:00:00

  • An investigation of automatic exposure control calibration for chest imaging with a computed radiography system.

    abstract::The purpose of this study was to examine the use of three physical image quality metrics in the calibration of an automatic exposure control (AEC) device for chest radiography with a computed radiography (CR) imaging system. The metrics assessed were signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and mean ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/9/2307

    authors: Moore CS,Wood TJ,Avery G,Balcam S,Needler L,Beavis AW,Saunderson JR

    更新日期:2014-05-07 00:00:00

  • Comment on 'egs_brachy: a versatile and fast Monte Carlo code for brachytherapy'.

    abstract::In a recent paper (Chamberland et al 2016 Phys. Med. Biol. 61 8214) develop a new Monte Carlo code called egs_brachy for brachytherapy treatments. It is based on EGSnrc, and written in the C++ programming language. In order to benchmark the egs_brachy code, the authors use it in various test case scenarios in which co...

    journal_title:Physics in medicine and biology

    pub_type: 评论,杂志文章,信件

    doi:10.1088/1361-6560/aa9ea1

    authors: Yegin G

    更新日期:2018-02-02 00:00:00

  • Modelling the temporal region in patients with temporal lobe epilepsy.

    abstract::EEG interictal epileptiform discharges in temporal lobe epilepsy are associated with magnetic fields. The maxima of magnetic spikes recorded over the spherical portions of the head appear fairly symmetric, whereas those over the lower temporal region often have irregular shapes. Furthermore, their magnitude is often u...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/32/1/009

    authors: Rose DF,Sato S,Smith PD,White J

    更新日期:1987-01-01 00:00:00

  • Improving source detection and separation in a spatiotemporal Bayesian inference dipole analysis.

    abstract::Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. If the actual time range of activity of sources is significantly shorter than the time range being analysed, the detectability, localization and time-course de...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/10/004

    authors: Jun SC,George JS,Plis SM,Ranken DM,Schmidt DM,Wood CC

    更新日期:2006-05-21 00:00:00