Development of a GSO positron/single-photon imaging detector.

abstract：:We recently started orthogonal two-port carbon ion therapy for choroidal melanoma with the intent to reduce the incidence of radiation complications that occur with mono-port therapy. Treatment planning techniques involving therapeutic beam characteristics are described here. The vertical (140 MeV/u) and horizontal (1...

journal_title：Physics in medicine and biology

authors： Koyama-Ito H,Kanai T,Minohara S,Tsuji H,Tsujii H

更新日期：2007-09-07 00:00:00

abstract：:Dynamic radiation therapy techniques require that the treatment head setup varies in time and space during dose delivery. Examples are leaf motion in intensity modulated x-ray therapy, modulator wheel rotation in conventional proton therapy and variable magnet settings in proton beam scanning. Consequently, for Monte ...

journal_title：Physics in medicine and biology

authors： Paganetti H

更新日期：2004-03-21 00:00:00

abstract：:All available imaging devices in nuclear medicine have finite energy resolution. This leads to inclusion of scattered radiation, which in turn degrades the image quality. Different scatter correction schemes therefore try to eliminate the effect of scattered radiation. On the other hand, improvement of the camera's in...

journal_title：Physics in medicine and biology

authors： Wirth V

更新日期：1989-01-01 00:00:00

abstract：:At the UMC Utrecht a prototype MR-linac has been installed. The system consists of an 8 MV Elekta linear accelerator and a 1.5 T Philips MRI system. This paper investigates the performance of the IC PROFILER™, a multi-axis ionization chamber array, in a 1.5 T magnetic field. The influence of the magnetic field on the ...

journal_title：Physics in medicine and biology

authors： Smit K,Kok JG,Lagendijk JJ,Raaymakers BW

更新日期：2014-04-07 00:00:00

abstract：:Range verification is one of the most relevant tasks in ion beam therapy. In the case of carbon ion therapy, positron emission tomography (PET) is the most widely used method for this purpose, which images the [Formula: see text]-activation following nuclear interactions of the ions with the tissue nuclei. Since the p...

journal_title：Physics in medicine and biology

authors： Hofmann T,Fochi A,Parodi K,Pinto M

更新日期：2019-05-21 00:00:00

abstract：:Non-invasively reconstructing the cardiac transmembrane potentials (TMPs) from body surface potentials can act as a regression problem. The support vector regression (SVR) method is often used to solve the regression problem, however the computational complexity of the SVR training algorithm is usually intensive. In t...

journal_title：Physics in medicine and biology

authors： Jiang M,Zhang H,Zhu L,Cao L,Wang Y,Xia L,Gong Y

更新日期：2015-04-21 00:00:00

abstract：:The origin of photons emitted in optical fibres under proton irradiation has been attributed to either entirely Čerenkov radiation or light consisting of fluorescence with a substantial amount of Čerenkov radiation. The source of the light emission is assessed in order to understand why the signal from optical fibres ...

journal_title：Physics in medicine and biology

authors： Brage Christensen J,Almhagen E,Nyström H,Andersen CE

更新日期：2018-03-09 00:00:00

abstract：:Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of disease and in situ evaluation of living tissue. The purpose of this article is to review the biological and physical basis of Raman spectroscopy of tissue, to assess the current status of the field and to explore future directions....

journal_title：Physics in medicine and biology

authors： Hanlon EB,Manoharan R,Koo TW,Shafer KE,Motz JT,Fitzmaurice M,Kramer JR,Itzkan I,Dasari RR,Feld MS

更新日期：2000-02-01 00:00:00

abstract：:The derivative at constant direction is frequently used in inversion of cone-beam data. Several algorithms for computing the derivative have been proposed in the literature. The best algorithm to date has been proposed recently by Noo et al (2007 Phys. Med. Biol. 52 5393-414). In this note we propose a new, simple and...

journal_title：Physics in medicine and biology

authors： Katsevich A

更新日期：2011-02-21 00:00:00

abstract：:Cone-beam computed tomography (CBCT) has rapidly become a clinically useful imaging modality for image-guided radiation therapy. Unfortunately, CBCT images of the thorax are susceptible to artefacts due to scattered photons, beam hardening, lag in data acquisition, and respiratory motion during a slow scan. These limi...

journal_title：Physics in medicine and biology

authors： Disher B,Hajdok G,Wang A,Craig J,Gaede S,Battista JJ

更新日期：2013-06-21 00:00:00

abstract：:None of the existing protocols or codes of practice for high-energy electron dosimetry take any account of the accelerator-generated bremsstrahlung always present in electron beams. This results in a systematic error in the derivation of the absorbed dose. The purpose of this study is to draw attention to this omissio...

journal_title：Physics in medicine and biology

authors： Klevenhagen SC

更新日期：1994-07-01 00:00:00

abstract：:Noise equivalent count rate (NECR) and image noise are two different but related metrics that have been used to predict and assess image quality, respectively. The aim of this study is to investigate, using patient studies, the relationships between injected dose (ID), body mass index (BMI) and scanner type on NECR an...

journal_title：Physics in medicine and biology

authors： Chang T,Chang G,Kohlmyer S,Clark JW,Rohren E,Mawlawi OR

更新日期：2011-08-21 00:00:00

abstract：:Prenatal events such as intrauterine growth restriction and increased cardiovascular risk in later life have been shown to be associated with an increased intima-media thickness (aIMT) of the abdominal aorta in the fetus. In order to assess and manage atherosclerosis and cardiovascular disease risk in adults and child...

journal_title：Physics in medicine and biology

authors： Veronese E,Tarroni G,Visentin S,Cosmi E,Linguraru MG,Grisan E

更新日期：2014-11-07 00:00:00

abstract：:Our aim is to investigate the impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging using a population of patient respiratory traces. A total of 1295 respiratory traces acquired during whole body PET/CT imaging were classified into three types according to the qualitative shape ...

journal_title：Physics in medicine and biology

authors： Liu C,Pierce LA 2nd,Alessio AM,Kinahan PE

更新日期：2009-12-21 00:00:00

abstract：:Several studies have been appeared, up to now, that indicate the effect of accurate simulation on dose received by different substructures of the eye, irradiated by external beams of short-range radiation such as electron. Different representations of the eye have consequently been introduced. Their accuracies depend ...

journal_title：Physics in medicine and biology

authors： Vejdani-Noghreiyan A,Ebrahimi-Khankook A

更新日期：2019-07-02 00:00:00

abstract：:The goal of this study was to determine the quantitative accuracy of our OSEM-APDI reconstruction method based on SPECT/CT imaging for Tc-99m, In-111, I-123, and I-131 isotopes. Phantom studies were performed on a SPECT/low-dose multislice CT system (Infinia-Hawkeye-4 slice, GE Healthcare) using clinical acquisition p...

journal_title：Physics in medicine and biology

authors： Shcherbinin S,Celler A,Belhocine T,Vanderwerf R,Driedger A

更新日期：2008-09-07 00:00:00

abstract：:Several methods of flip angle mapping for magnetic resonance imaging have been proposed. We evaluated the accuracy of five methods of flip angle measurement in the presence of measurement noise. Our analysis was performed in a closed form by propagation of probability density functions (PDFs). The flip angle mapping m...

journal_title：Physics in medicine and biology

authors： Morrell GR,Schabel MC

更新日期：2010-10-21 00:00:00

abstract：:The Monte Carlo method is the most accurate method for radiotherapy dose calculations, if used correctly. However, any Monte Carlo dose calculation is burdened with statistical noise. In this paper, denoising of Monte Carlo dose distributions with a three-dimensional adaptive anisotropic diffusion method was investiga...

journal_title：Physics in medicine and biology

authors： Miao B,Jeraj R,Bao S,Mackie TR

更新日期：2003-09-07 00:00:00

abstract：:The Studsvik thermal-neutron facility was originally designed for neutron capture radiography (NCR) at high thermal-neutron fluence and low fast-neutron contamination. It has now been modified to permit irradiation of living cells and animals without the need for stopping and restarting the R2-0 reactor. Previous calc...

journal_title：Physics in medicine and biology

authors： Pettersson OA,Chiangmai SN,Grusell E,Larsson B

更新日期：1993-08-01 00:00:00

abstract：:The imaging performance of a high-resolution preclinical micro-positron emission tomography (micro-PET) system employing liquid xenon (LXe) as the gamma-ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection ionization chambers and two arrays of ...

journal_title：Physics in medicine and biology

authors： Miceli A,Glister J,Andreyev A,Bryman D,Kurchaninov L,Lu P,Muennich A,Retiere F,Sossi V

更新日期：2012-03-21 00:00:00

abstract：:For the first time, three-dimensional images of the newborn infant brain have been generated using measurements of transmitted light. A 32-channel time-resolved imaging system was employed, and data were acquired using custom-made helmets which couple source fibres and detector bundles to the infant head. Images have ...

journal_title：Physics in medicine and biology

authors： Hebden JC,Gibson A,Yusof RM,Everdell N,Hillman EM,Delpy DT,Arridge SR,Austin T,Meek JH,Wyatt JS

更新日期：2002-12-07 00:00:00

abstract：:Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be ...

journal_title：Physics in medicine and biology

authors： Flach B,Brehm M,Sawall S,Kachelrieß M

更新日期：2014-12-21 00:00:00

abstract：:Online adaptive radiation therapy (ART) based on real-time magnetic resonance imaging represents a paradigm-changing treatment scheme. However, conventional quality assurance (QA) methods based on phantom measurements are not feasible with the patient on the treatment couch. The purpose of this work is to develop a fa...

journal_title：Physics in medicine and biology

authors： Wang Y,Mazur TR,Park JC,Yang D,Mutic S,Li HH

更新日期：2017-06-21 00:00:00

abstract：:The inadequate visibility of microcalcifications-small calcium deposits that cue radiologists to early stages of cancer-is a major limitation in current designs of dedicated breast computed tomography (bCT). This limitation has previously been attributed to the constituent components, spatial resolution, and utilized ...

journal_title：Physics in medicine and biology

authors： Ghazi P

更新日期：2020-12-04 00:00:00

abstract：:Computer tomographic (CT) scans are used to correct for tissue inhomogeneities in radiotherapy treatment planning. In order to guarantee a precise treatment, it is important to obtain the relationship between CT Hounsfield units and electron densities (or proton stopping powers for proton radiotherapy), which is the b...

journal_title：Physics in medicine and biology

authors： Schneider U,Pedroni E,Lomax A

更新日期：1996-01-01 00:00:00

abstract：:A novel radiation targeted therapy is investigated for HER-2 positive breast cancers. The proposed concept combines two known approaches, but never used together for the treatment of advanced, relapsed or metastasized HER-2 positive breast cancers. The proposed radiation binary targeted concept is based on the anti HE...

journal_title：Physics in medicine and biology

authors： Mundy DW,Harb W,Jevremovic T

更新日期：2006-03-21 00:00:00

abstract：:Stroke lesion volume is a key radiologic measurement in assessing prognosis of acute ischemic stroke (AIS) patients. The aim of this paper is to develop an automated segmentation method for accurately segmenting follow-up ischemic and hemorrhagic lesion from multislice non-contrast CT (NCCT) volumes of AIS patients. T...

journal_title：Physics in medicine and biology

authors： Kuang H,Menon BK,Qiu W

更新日期：2020-11-05 00:00:00

abstract：:Skin toxicity has been reported for IMRT of head and neck cancer. The purpose of this study was to investigate the dose in the build-up region delivered by a 6 MV treatment plan for which important skin toxicity was observed. We also investigated if the different designs of the treatment head of an Elekta and a Varian...

journal_title：Physics in medicine and biology

authors： Paelinck L,De Wagter C,Van Esch A,Duthoy W,Depuydt T,De Neve W

更新日期：2005-02-07 00:00:00

abstract：:This paper evaluates the performance of two large-area position-sensitive solid-state photomultipliers (PS-SSPM) for use in small animal PET detector designs. Both PS-SSPM device designs are 1 cm² in area, the first being a 2 × 2 tiled array of 5 mm × 5 mm PS-SSPMs and the second being a 10 mm × 10 mm continuous PS-SS...

journal_title：Physics in medicine and biology

authors： Schmall JP,Du J,Yang Y,Dokhale PA,McClish M,Christian J,Shah KS,Cherry SR

更新日期：2012-12-21 00:00:00

abstract：:The current UK code of practice for high-energy photon therapy dosimetry (Lillicrap et al 1990 Phys. Med. Biol. 35 1355-60) gives instructions for measuring absorbed dose to water under reference conditions for megavoltage photons. The reference conditions and the index used to specify beam quality require that a mach...

journal_title：Physics in medicine and biology

authors： Thomas SJ,Aspradakis MM,Byrne JP,Chalmers G,Duane S,Rogers J,Thomas RA,Tudor GS,Twyman N,IPEM Working Party.

更新日期：2014-03-21 00:00:00