The modulation transfer function of an optical coherence tomography imaging system in turbid media.

abstract：:Finding fluence maps for intensity-modulated radiation therapy (IMRT) can be formulated as a multi-criteria optimization problem for which Pareto optimal treatment plans exist. To account for the dose-per-fraction effect of fractionated IMRT, it is desirable to exploit radiobiological treatment plan evaluation criteri...

journal_title：Physics in medicine and biology

authors： Hoffmann AL,den Hertog D,Siem AY,Kaanders JH,Huizenga H

更新日期：2008-11-21 00:00:00

abstract：:We present a method to include robustness in a multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one to simultaneously explore the trade-off between different objectives as well as the trade-off between robustness and nominal plan quality. In MCO, a database...

journal_title：Physics in medicine and biology

authors： Chen W,Unkelbach J,Trofimov A,Madden T,Kooy H,Bortfeld T,Craft D

更新日期：2012-02-07 00:00:00

abstract：:We comment on a recent article (Gomà et al 2014 Phys. Med. Biol. 59 4961-71) which compares different routes of reference dosimetry for the energy dependent beam monitor calibration in scanned proton beams. In this article, a 3% discrepancy is reported between a Faraday cup and a plane-parallel ionization chamber in t...

journal_title：Physics in medicine and biology

authors： Palmans H,Vatnitsky SM

更新日期：2016-09-07 00:00:00

abstract：:In recent years, there has been an increase in the popularity of light-emitting diode (LED)-based, battery-powered transilluminators (BPTs) for facilitating transdermal vascular access in adults and neonates. BPTs are believed to have lower potential for inducing skin burns than prior devices based on high-power broad...

journal_title：Physics in medicine and biology

authors： Pfefer TJ,Mehrabi A,James R,Landry R,Weininger S,Chang I,Kaufman D,Miller S

更新日期：2009-11-21 00:00:00

abstract：:Intensity modulated particle therapy (IMPT) with carbon ions can generate highly conformal treatment plans; however, IMPT is limited in robustness against range and positioning uncertainty. This is particularly true for moving targets, even though all motion states of a 4DCT are considered in 4D-IMPT. Here, we expand ...

journal_title：Physics in medicine and biology

authors： Wolf M,Anderle K,Durante M,Graeff C

更新日期：2020-11-06 00:00:00

abstract：:Using Cherenkov radiation in positron emission tomography (PET) has the potential to improve the time of flight (TOF) resolution and reduce the cost of detectors. In previous studies promising TOF results were achieved when lead fluoride (PbF2) crystals were used instead of a scintillator. In this work, a whole-body P...

journal_title：Physics in medicine and biology

authors： Consuegra D,Korpar S,Križan P,Pestotnik R,Razdevšek G,Dolenec R

更新日期：2020-03-06 00:00:00

abstract：:Scatter correction is an essential technique to improve the image quality of cone-beam CT (CBCT). Although different scatter correction methods have been proposed in the literature, a standard solution is still being studied due to the limitations including accuracy, computation efficiency and generalization. In this ...

journal_title：Physics in medicine and biology

authors： Jiang Y,Yang C,Yang P,Hu X,Luo C,Xue Y,Xu L,Hu X,Zhang L,Wang J,Sheng K,Niu T

更新日期：2019-07-11 00:00:00

abstract：:Results from dielectric studies on the freshwater fish Cyprinus carpio exposed to a sublethal concentration of sodium alkyl benzene sulphonate were compared with those from untreated control fish; recovery from the test solution was also checked. The influence of the anionic detergent on the intracellular matter of fi...

journal_title：Physics in medicine and biology

authors： Bielinska I,Terlecki J

更新日期：1984-05-01 00:00:00

abstract：:A three-dimensional spherical inclusion model that approximates a lesion bonded to a tissue matrix is proposed for biomedical elastography. Analytical formulae describing spatial strain and stress distributions generated in infinite media by uniform loading are given under a linear, homogeneous, isotropic elasticity a...

journal_title：Physics in medicine and biology

authors： Bilgen M,Insana MF

更新日期：1998-01-01 00:00:00

abstract：:Diffusion tensor tractography (DTT) allows one to explore axonal connectivity patterns in neuronal tissue by linking local predominant diffusion directions determined by diffusion tensor imaging (DTI). The majority of existing tractography approaches use continuous coordinates for calculating single trajectories throu...

journal_title：Physics in medicine and biology

authors： Bodammer NC,Kaufmann J,Kanowski M,Tempelmann C

更新日期：2009-02-21 00:00:00

abstract：:We present a new image reconstruction algorithm for helical cone-beam computed tomography (CT). This algorithm is designed for data collected at or near maximum pitch, and provides a theoretically exact and stable reconstruction while beneficially using all measured data. The main operations involved are a differentia...

journal_title：Physics in medicine and biology

authors： Schöndube H,Stierstorfer K,Noo F

更新日期：2009-08-07 00:00:00

abstract：:Iterative tomographic reconstruction has been established as a viable alternative for data analysis in phase-sensitive x-ray imaging based on the edge-illumination principle. However, previously published approaches did not account for drifts of optical elements during a scan, which can lead to artefacts. Up to now, t...

journal_title：Physics in medicine and biology

authors： Modregger P,Meganck J,Hagen CK,Massimi L,Olivo A,Endrizzi M

更新日期：2019-10-10 00:00:00

abstract：:Treatment planning based on probability distribution function (PDF) of patient geometries has been shown a potential off-line strategy to incorporate organ motion, but the application of such approach highly depends upon the reproducibility of the PDF. In this paper, we investigated the dependences of the PDF reproduc...

journal_title：Physics in medicine and biology

authors： Cai J,Read PW,Altes TA,Molloy JA,Brookeman JR,Sheng K

更新日期：2007-01-21 00:00:00

abstract：:This work is a follow-up study for a recently-proposed 3D radiochromic gel dosimeter that contains a tetrazolium salt and a physical gel matrix made of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127). Several tetrazolium salts were examined in this work, including tetrazoli...

journal_title：Physics in medicine and biology

authors： Kwiatos K,Maras P,Kadlubowski S,Stempień Z,Dudek M,Kozicki M

更新日期：2018-05-04 00:00:00

abstract：:A general theory is presented for minimizing noise in linear dimension reduction of sequences of medical images when the factors and the covariance matrix and mean of the noise are given. A dimension reduction is optimal when all diagonal elements in the covariance matrix of the noise in the signal (factor) space are ...

journal_title：Physics in medicine and biology

authors： Hermansen F,Lammertsma AA

更新日期：1995-11-01 00:00:00

abstract：:A silicon semiconductor photodiode was used to measure the TL-signal of TLD-300 (CaF2:Tm) detectors irradiated with 60Co gamma rays and 226Ra alpha particles. The applied dose values varied from 0.12 to 14.3 Gy for gamma rays and from about 50 to 300 Gy for alpha particles. Because of the infrared sensitivity of the p...

journal_title：Physics in medicine and biology

authors： Meissner P,Jacob M,Rassow J

更新日期：1988-12-01 00:00:00

abstract：:We experimentally investigated the SPECT recovery of I-131 activity in multiple spheres located simultaneously at different locations within a cylindrical phantom that had an elliptical cross section. The sphere volumes ranged from 209 cc down to 4.2 cc. A Prism 3000 camera and two types of parallel-hexagonal-hole col...

journal_title：Physics in medicine and biology

authors： Koral KF,Yendiki A,Dewaraja YK

更新日期：2007-02-07 00:00:00

abstract：:In this paper, we investigate an off-line strategy to incorporate inter-fraction organ motion in IMRT treatment planning. It was suggested that inverse planning could be based on a probability distribution of patient geometries instead of a single snap shot. However, this concept is connected to two intrinsic problems...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2004-09-07 00:00:00

abstract：:We compare two different implementations of a 3D SPECT system model for iterative reconstruction, both of which compensate for non-uniform photon attenuation and depth-dependent system response. One implementation performs fast rotation of images represented using a basis of rectangular voxels, whereas the other repre...

journal_title：Physics in medicine and biology

authors： Yendiki A,Fessler JA

更新日期：2004-06-07 00:00:00

abstract：:We have developed an x-ray imaging system for in vivo four-dimensional computed tomography (4DCT) of small animals for pre-clinical lung investigations. Our customized laboratory facility is capable of high resolution in vivo imaging at high frame rates. Characterization using phantoms demonstrate a spatial resolution...

journal_title：Physics in medicine and biology

authors： Preissner M,Murrie RP,Pinar I,Werdiger F,Carnibella RP,Zosky GR,Fouras A,Dubsky S

更新日期：2018-04-20 00:00:00

abstract：:Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in...

journal_title：Physics in medicine and biology

authors： Kim KS,Ye JC

更新日期：2011-08-07 00:00:00

abstract：:The stochastic nature of cavitation implies visualization of the cavitation cloud in real-time and in a discriminative manner for the safe use of focused ultrasound therapy. This visualization is sometimes possible with standard echography, but it strongly depends on the quality of the scanner, and is hindered by diff...

journal_title：Physics in medicine and biology

authors： Arnal B,Baranger J,Demene C,Tanter M,Pernot M

更新日期：2017-02-07 00:00:00

abstract：:[(18)F]Fluorothymidine (FLT) is a cell proliferation marker that undergoes predominantly hepatic metabolism and therefore shows a high level of accumulation in the liver, as well as in rapidly proliferating tumours. Furthermore, the tracer's uptake is substantial in other organs including the heart. We present a nonli...

journal_title：Physics in medicine and biology

authors： Gray KR,Contractor KB,Kenny LM,Al-Nahhas A,Shousha S,Stebbing J,Wasan HS,Coombes RC,Aboagye EO,Turkheimer FE,Rosso L

更新日期：2010-02-07 00:00:00

abstract：:This paper presents a computer simulation of photon interaction with collimator septa, which allows the point spread function of scintillation camera collimators to be calculated. The method simulates photon attenuation along their propagation direction in a determinist way. Using this simulation, the spatial resoluti...

journal_title：Physics in medicine and biology

authors： Gantet P,Esquerré JP,Danet B,Guiraud R

更新日期：1990-05-01 00:00:00

abstract：:Clinical diffusion MRI (dMRI) is sensitive to micrometer scale spin displacements, but the image resolution is  ∼mm, so the biophysical interpretation of the signal relies on establishing appropriate subvoxel tissue models. A class of two-compartment exchange models originally proposed by Kärger have been used success...

journal_title：Physics in medicine and biology

authors： Naughton NM,Georgiadis JG

更新日期：2019-08-01 00:00:00

abstract：:We give an overview of the role of Physics in Medicine and Biology in the development of tomographic reconstruction algorithms. We focus on imaging modalities involving ionizing radiation, CT, PET and SPECT, and cover a wide spectrum of reconstruction problems, starting with classical 2D tomography in the 1970s up to ...

journal_title：Physics in medicine and biology

authors： Defrise M,Gullberg GT

更新日期：2006-07-07 00:00:00

abstract：:The advent of real-time ultrasound in the 1970s, together with a growing interest in tissue characterization, led to a number of investigators using the nature of tissue motion to distinguish healthy from diseased tissue. Our group at the (then) Ultrasonics Institute demonstrated the use of phase methods for detecting...

journal_title：Physics in medicine and biology

authors： Wilson LS,Robinson DE,Dadd MJ

更新日期：2000-06-01 00:00:00

abstract：:Tumour histological grade has prognostic implications in breast cancer. Tumour features in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and T2-weighted (T2W) imaging can provide related and complementary information in the analysis of breast lesions to improve MRI-based histological status prediction...

journal_title：Physics in medicine and biology

authors： Fan M,Liu Z,Xie S,Xu M,Wang S,Gao X,Li L

更新日期：2019-10-23 00:00:00

abstract：:A new mathematical model of the head has been constructed from a set of serial MRI slices from one subject. Finite-difference time-domain (FDTD) calculations of the specific energy absorption rate (SAR) have been performed on this model with a 2 mm resolution for a generic mobile communication transceiver represented ...

journal_title：Physics in medicine and biology

authors： Dimbylow PJ,Mann SM

更新日期：1994-10-01 00:00:00

abstract：:Scanned ion pencil beams carry a low-dose envelope which can extend up to several centimeters from the individual beam central axis. Depending on the energy and species of the beam, this halo consists mainly of secondary particles produced by nuclear interactions in the target or of particles undergoing multiple Coulo...

journal_title：Physics in medicine and biology

authors： Schwaab J,Brons S,Fieres J,Parodi K

更新日期：2011-12-21 00:00:00