Characterization of 3D joint space morphology using an electrostatic model (with application to osteoarthritis).

abstract：:Many models exist for predicting toxicities based on dose-volume histograms (DVHs) or dose-surface histograms (DSHs). This approach has several drawbacks as firstly the reduction of the dose distribution to a histogram results in the loss of spatial information and secondly the bins of the histograms are highly correl...

journal_title：Physics in medicine and biology

authors： Buettner F,Gulliford SL,Webb S,Partridge M

更新日期：2011-04-07 00:00:00

abstract：:Scattered doses, e.g. neutron doses in proton therapy, are of concern in radiation therapy. Although measured data are the gold standard, Monte Carlo simulations allow a more realistic consideration of patient anatomy via whole-body phantoms. When calculating neutron doses with Monte Carlo techniques, the dose can be ...

journal_title：Physics in medicine and biology

authors： Jarlskog CZ,Paganetti H

更新日期：2008-09-07 00:00:00

abstract：:A circular scanning trajectory is and will likely remain a popular choice of trajectory in computed tomography (CT) imaging because it is easy to implement and control. Filtered-backprojection (FBP)-based algorithms have been developed previously for approximate and exact reconstruction of the entire image or a region...

journal_title：Physics in medicine and biology

authors： Pan X,Xia D,Zou Y,Yu L

更新日期：2004-09-21 00:00:00

abstract：:Four-dimensional (4D) methods strive to achieve highly conformal radiotherapy, particularly for lung and breast tumours, in the presence of respiratory-induced motion of tumours and normal tissues. Four-dimensional radiotherapy accounts for respiratory motion during imaging, planning and radiation delivery, and requir...

journal_title：Physics in medicine and biology

authors： Vedam SS,Keall PJ,Kini VR,Mostafavi H,Shukla HP,Mohan R

更新日期：2003-01-07 00:00:00

abstract：:Burst-tone focused ultrasound exposure in the presence of microbubbles has been demonstrated to be effective at inducing temporal and local opening of the blood-brain barrier (BBB), which promises significant clinical potential to deliver therapeutic molecules into the central nervous system (CNS). Traditional contras...

journal_title：Physics in medicine and biology

authors： Tsai CH,Zhang JW,Liao YY,Liu HL

更新日期：2016-04-07 00:00:00

abstract：:In BANG gel dosimetry, the spin-spin relaxation rate, R2 = I/T2, is related to the radiation dose that has been delivered to the gel phantom. R2 is calculated by fitting the pixel intensities of a set of differently T2-weighted base images. In gel dosimetry for radiotherapy, an accuracy of 5% in dose and 3 mm spatiall...

journal_title：Physics in medicine and biology

authors： De Deene Y,De Wagter C,De Neve W,Achten E

更新日期：2000-07-01 00:00:00

abstract：:In this work we present the first delivery of intensity modulated arc therapy on the Elekta Unity 1.5 T MR-linac. The machine's current IMRT based control system was modified suitably to enable dynamic delivery of radiation, for the purpose of exploring MRI-guided radiation therapy adaptation modes in a research setti...

journal_title：Physics in medicine and biology

authors： Kontaxis C,Woodhead PL,Bol GH,Lagendijk JJW,Raaymakers BW

更新日期：2020-12-23 00:00:00

abstract：:Although radionuclide therapy has been around for a long time, this modality of cancer treatment has been limited mainly to the use of [32P]-phosphate and [131I]-sodium iodide. The last few years, however, have seen an increased interest in this area due to new developments of radionuclides and carrier molecules that ...

journal_title：Physics in medicine and biology

authors： Zweit J

更新日期：1996-10-01 00:00:00

abstract：:The objective of this work is to test analytical models to calculate the luminescence efficiency of Al(2)O(3):C optically stimulated luminescence detectors (OSLDs) exposed to heavy charged particles with energies relevant to space dosimetry and particle therapy. We used the track structure model to obtain an analytica...

journal_title：Physics in medicine and biology

authors： Sawakuchi GO,Yukihara EG

更新日期：2012-01-21 00:00:00

abstract：:The prompt-gamma neutron activation facility at Brookhaven National Laboratory was upgraded to improve both the precision and accuracy of its in vivo determinations of total body nitrogen. The upgrade, guided by Monte Carlo simulations, involved elongating and modifying the source collimator and its shielding, reposit...

journal_title：Physics in medicine and biology

authors： Dilmanian FA,Lidofsky LJ,Stamatelatos I,Kamen Y,Yasumura S,Vartsky D,Pierson RN Jr,Weber DA,Moore RI,Ma R

更新日期：1998-02-01 00:00:00

abstract：:Usually, Monte Carlo models are validated against experimental data. However, models of multiple Coulomb scattering (MCS) in the Gaussian approximation are exceptional in that we have theories which are probably more accurate than the experiments which have, so far, been done to test them. In problems directly sensiti...

journal_title：Physics in medicine and biology

authors： Makarova A,Gottschalk B,Sauerwein W

更新日期：2017-07-06 00:00:00

abstract：:Recently, the Task Group 103 of the International Commission on Radiological Protection (ICRP) has developed new mesh-type reference computational phantoms (MRCPs) for adult male and female. When compared to the current voxel-type reference computational phantoms in ICRP Publication 110, the MRCPs have several advanta...

journal_title：Physics in medicine and biology

authors： Lee H,Yeom YS,Nguyen TT,Choi C,Han H,Shin B,Zhang X,Kim CH,Chung BS,Zankl M

更新日期：2019-02-05 00:00:00

abstract：:In vitro dielectric properties of ageing porcine tissues were measured in the frequency range of 50 MHz-20 GHz, and the total combined uncertainties of the measurements were assessed. The results show statistically significant reduction with age in both permittivity and conductivity of 10 out of 15 measured tissues. A...

journal_title：Physics in medicine and biology

authors： Peyman A,Gabriel C,Grant EH,Vermeeren G,Martens L

更新日期：2009-01-21 00:00:00

abstract：:A method of computing theoretical X-ray spectra in the range 30-150 kV is presented. The theoretical spectra are compared with constant potential, high resolution spectra from a tungsten target measured with a Ge(Li) detector, for a range of target angles, tube voltage and filtrations. Above 100 kV the spectra were al...

journal_title：Physics in medicine and biology

authors： Birch R,Marshall M

更新日期：1979-05-01 00:00:00

abstract：:Distributions of linear pathlength measurements have been utilized in skeletal dosimetry of internally emitted short-range particles for over 30 years. This work reviews the methods for coupling these distributions to range-energy data. A revised methodology is presented for handling the insertion of the additional do...

journal_title：Physics in medicine and biology

authors： Jokisch DW,Rajon DA,Patton PW,Bolch WE

更新日期：2011-05-07 00:00:00

abstract：:Dynamic modulation can be affected by inaccuracies when the required acceleration is larger than the highest allowed by the mechanical characteristics of the whole apparatus. In this study, inertia effects have been investigated with regard to the single absorber 1D modulation, analysing primarily how the acceleration...

journal_title：Physics in medicine and biology

authors： Corletto D,Broggi S,Fiorino C,Mangili P,Calandrino R,Lev A,Gennari D,Rudello F

更新日期：1999-11-01 00:00:00

abstract：:Recent acute shortage of medical radioisotopes prompted investigations into alternative methods of production and the use of a cyclotron and ¹⁰⁰Mo(p,2n)(99m)Tc reaction has been considered. In this context, the production yields of (99m)Tc and various other radioactive and stable isotopes which will be created in the ...

journal_title：Physics in medicine and biology

authors： Celler A,Hou X,Bénard F,Ruth T

更新日期：2011-09-07 00:00:00

abstract：:Ionization quenching in ion beam dosimetry is often related to the fluence- or dose-averaged linear energy transfer (LET). Both quantities are however averaged over a wide LET range and a mixed field of primary and secondary ions. We propose a novel method to correct the quenched luminescence in scintillators exposed ...

journal_title：Physics in medicine and biology

authors： Christensen JB,Almhagen E,Stolarczyk L,Vestergaard A,Bassler N,Andersen CE

更新日期：2019-04-29 00:00:00

abstract：:Today, new single photon emission computed tomography (SPECT) reconstruction techniques rely on accurate Monte Carlo (MC) simulations to optimize reconstructed images. However, existing MC scintillation camera models which usually include an accurate description of the collimator and crystal, lack correct implementati...

journal_title：Physics in medicine and biology

authors： Rault E,Staelens S,Van Holen R,De Beenhouwer J,Vandenberghe S

更新日期：2011-01-07 00:00:00

abstract：:This paper introduces a spatial-diversity method for speckle suppression in optical coherence microscopy. The method is based on combining interference signals from an array of detectors placed in the back focal plane of the objective lens, such that elements receive light backscattered from the sample volume at diffe...

journal_title：Physics in medicine and biology

authors： Schmitt JM

更新日期：1997-07-01 00:00:00

abstract：:In brachytherapy, plans are routinely calculated using the AAPM TG43 formalism which considers the patient as a simple water object. An accurate modeling of the physical processes considering patient heterogeneity using Monte Carlo simulation (MCS) methods is currently too time-consuming and computationally demanding ...

journal_title：Physics in medicine and biology

authors： Lemaréchal Y,Bert J,Falconnet C,Després P,Valeri A,Schick U,Pradier O,Garcia MP,Boussion N,Visvikis D

更新日期：2015-07-07 00:00:00

abstract：:Ultrasound may provide a quantitative technique for the characterization of cartilage changes typical of early osteoarthrosis. In this study, specific changes in bovine articular cartilage were induced using collagenase and chondroitinase ABC, enzymes that selectively degrade collagen fibril network and digest proteog...

journal_title：Physics in medicine and biology

authors： Töyräs J,Rieppo J,Nieminen MT,Helminen HJ,Jurvelin JS

更新日期：1999-11-01 00:00:00

abstract：:We describe an improved algorithm for localising equivalent sources of biomagnetic fields in the human brain. The algorithm is an improvement over the sphere model in that it considers two distinct surfaces: an ellipsoid, to model the region of the skull on which the sensors are placed, and a sphere as the medium in w...

journal_title：Physics in medicine and biology

authors： Pistella F,Barone P,Narici L,Ocello N,Pizzella V,Romani GL

更新日期：1987-01-01 00:00:00

abstract：:The absolute dose rate around beta sources for intravascular brachytherapy was measured with thin thermoluminescent (TL) dosimeters and radiochromic film. The calibration of these dosimeters was performed at the dose maximum in a 6 MeV electron beam of a linear accelerator. Compared to the values given by the manufact...

journal_title：Physics in medicine and biology

authors： Piessens M,Reynaert N

更新日期：2000-08-01 00:00:00

abstract：:Determination of the cardiorespiratory phase of the heart has numerous applications during cardiac imaging. In this article we propose a novel view-angle independent near-real time cardiorespiratory motion gating and coronary sinus (CS) catheter tracking technique for x-ray fluoroscopy images that are used to guide ca...

journal_title：Physics in medicine and biology

authors： Panayiotou M,Rhode KS,King AP,Ma Y,Cooklin M,O'Neill M,Gill J,Rinaldi CA,Housden RJ

更新日期：2015-10-21 00:00:00

abstract：:Online proton range/dose verification based on measurements of proton-induced positron emitters is a promising strategy for quality assurance in proton therapy. Because of the nonlinear correlation between the dose distribution and the activity distribution of positron emitters, we aim to establish their relationship ...

journal_title：Physics in medicine and biology

authors： Liu C,Li Z,Hu W,Xing L,Peng H

更新日期：2019-09-04 00:00:00

abstract：:The purpose of this paper was to study the source model for a Monte Carlo simulation of electron beams from a medical linear accelerator. In a prior study, a non-divergent Gaussian source with a full-width at half-maximum (FWHM) of 0.15 cm was successful in predicting relative dose distributions for electron beams wit...

journal_title：Physics in medicine and biology

authors： Weinberg R,Antolak JA,Starkschall G,Kudchadker RJ,White RA,Hogstrom KR

更新日期：2009-01-07 00:00:00

abstract：:The purpose of this study was to validate the accuracy and reliability of volume measurements obtained using three-dimensional (3D) thoracoscopic ultrasound (US) imaging. Artificial "tumours" were created by injecting a liquid agar mixture into spherical moulds of known volume. Once solidified, the "tumours" were impl...

journal_title：Physics in medicine and biology

authors： Hornblower VD,Yu E,Fenster A,Battista JJ,Malthaner RA

更新日期：2007-01-07 00:00:00

abstract：:We show that it is possible to translate an intensity modulated radiation therapy (IMRT) treatment plan and deliver it as a single arc. This technique is referred to in this paper as aperture modulation arc therapy (AMAT). During this arc, the MLC leaves do not conform to the projection of the target PTV and the machi...

journal_title：Physics in medicine and biology

authors： Crooks SM,Wu X,Takita C,Watzich M,Xing L

更新日期：2003-05-21 00:00:00

abstract：:The dearth of information on the physical processes involved in the propagation of ultrasound in tissue and the growing need for such information are discussed. The physical nature of the ultrasonic diagnostic process in considered in terms of a wave phenomenon and the limitations and advantages of frequency spectral ...

journal_title：Physics in medicine and biology

authors： Chivers RC,Hill CR

更新日期：1975-09-01 00:00:00