Improvement of the prompt-gamma neutron activation facility at Brookhaven National Laboratory.

abstract：:Images of the human retina are routinely used in clinical practice for the diagnosis and management of eye disease. Increased permeability of retinal blood vessels, which is a clinically significant feature, can be visualized with a process known as fluorescein angiography as leakage of fluorescence dye into the surro...

journal_title：Physics in medicine and biology

authors： Cree MJ,Olson JA,McHardy KC,Sharp PF,Forrester JV

更新日期：1999-01-01 00:00:00

abstract：:A system is described in which large superficial areas of tissue may be heated using a single plane ultrasonic transducer scanned in a raster fashion. The shape of the heated area is determined by the movement of a microswitch which is activated when it strikes the rigid edge of a hole of the required shape cut in a p...

journal_title：Physics in medicine and biology

authors： ter Haar G,Hopewell JW

更新日期：1985-12-01 00:00:00

abstract：:As a part of an ongoing effort to develop computerized planning tools for cryosurgery, an experimental study has been conducted to verify a recently developed numerical technique for bioheat transfer simulations. Experiments were performed on gelatin solution as a phantom material, using proprietary liquid-nitrogen cr...

journal_title：Physics in medicine and biology

authors： Rossi MR,Rabin Y

更新日期：2007-08-07 00:00:00

abstract：:This work aims to develop, implement and validate a Monte Carlo (MC)-based independent dose calculation (IDC) framework to perform patient-specific quality assurance (QA) for multi-leaf collimator (MLC)-based CyberKnife® (Accuray Inc., Sunnyvale, CA) treatment plans. The IDC framework uses an XML-format treatment plan...

journal_title：Physics in medicine and biology

authors： Mackeprang PH,Vuong D,Volken W,Henzen D,Schmidhalter D,Malthaner M,Mueller S,Frei D,Stampanoni MFM,Dal Pra A,Aebersold DM,Fix MK,Manser P

更新日期：2017-12-19 00:00:00

abstract：:Most solid-state detectors, including 3D dosimeters, show lower signal in the Bragg peak than expected, a process termed quenching. The purpose of this study was to investigate how variation in chemical composition of a recently developed radiochromic, silicone-based 3D dosimeter influences the observed quenching in p...

journal_title：Physics in medicine and biology

authors： Høye EM,Skyt PS,Balling P,Muren LP,Taasti VT,Swakoń J,Mierzwińska G,Rydygier M,Bassler N,Petersen JB

更新日期：2017-02-21 00:00:00

abstract：:This paper describes a neural network (NN) regression model for relative dose computation. The input signal of the NN model includes depths and field sizes and the output is the relative dose, for example, percentage depth dose (%DD) or tissue-air ratio (TAR) in this paper. After a functional link has been created, th...

journal_title：Physics in medicine and biology

authors： Wu X,Zhu Y

更新日期：2000-04-01 00:00:00

abstract：:In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultr...

journal_title：Physics in medicine and biology

authors： Ma R,Zhou X,Zhang S,Yin T,Liu Z

更新日期：2016-12-21 00:00:00

abstract：:As automation in radiation oncology becomes more common, it is important to determine which algorithms are equivalent for a given workflow. Often, algorithm comparisons are performed in isolation; however, clinical context can provide valuable insight into the importance of algorithm features and error magnification i...

journal_title：Physics in medicine and biology

authors： Weppler S,Schinkel C,Kirkby C,Smith W

更新日期：2020-09-28 00:00:00

abstract：:An accurate, low noise estimate of photon attenuation in the subject is required for quantitative microPET studies of molecular tracer distributions in vivo. In this work, several transmission-based measurement techniques were compared, including coincidence mode with and without rod windowing, singles mode with two d...

journal_title：Physics in medicine and biology

authors： Lehnert W,Meikle SR,Siegel S,Newport D,Banati RB,Rosenfeld AB

更新日期：2006-08-21 00:00:00

abstract：:The design, construction and use of a large-scale field-cycled proton-electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magn...

journal_title：Physics in medicine and biology

authors： Lurie DJ,Foster MA,Yeung D,Hutchison JM

更新日期：1998-07-01 00:00:00

abstract：:Dynamic contrast enhanced MRI (DCE-MRI) and pharmacokinetic models have been used to measure tumour permeability (K(trans)) and leakage volume (ve) in numerous studies. The construction of pharmacokinetic models describing such tissue properties relies on defining the blood plasma concentration of contrast agent with ...

journal_title：Physics in medicine and biology

authors： Ahearn TS,Staff RT,Redpath TW,Semple SI

更新日期：2004-05-21 00:00:00

abstract：:Segmentation is often required for the analysis of dynamic positron emission tomography (PET) images. However, noise and low spatial resolution make it a difficult task and several supervised and unsupervised methods have been proposed in the literature to perform the segmentation based on semi-automatic clustering of...

journal_title：Physics in medicine and biology

authors： Mouysset S,Zbib H,Stute S,Girault JM,Charara J,Noailles J,Chalon S,Buvat I,Tauber C

更新日期：2013-10-07 00:00:00

abstract：:Monte Carlo simulation techniques are applied to track the annihilation photons from positron decay, and store the photon histories. Reasonably realistic models of the isotope distribution in the brain and heart during typical PET studies, as well as the traditional phantoms used for measuring PET scanner performance ...

journal_title：Physics in medicine and biology

authors： Thompson CJ,Moreno-Cantu J,Picard Y

更新日期：1992-03-01 00:00:00

abstract：:At low and intermediate frequencies, the strength of the induced electric field is used as dosimetric quantity for human protection in the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines. To compute the induced electric field, numerical methods based on anatomically realistic voxel mo...

journal_title：Physics in medicine and biology

authors： Soldati M,Laakso I

更新日期：2020-01-10 00:00:00

abstract：:In vivo neutron activation analysis was used to measure total body sodium and chlorine in 18 male and 18 female normal adults. Corrections for body size were developed. Normalisation factors were derived which enable the prediction of the normal levels of sodium and chlorine in a subject. The coefficient of variation ...

journal_title：Physics in medicine and biology

authors： Kennedy NS,Eastell R,Smith MA,Tothill P

更新日期：1983-03-01 00:00:00

abstract：:The origin of the differences in the refractive index observed between normal and tumor tissues using terahertz spectroscopy has been described quantitatively. To estimate water content differences in tissues, we prepared fresh and paraffin-embedded samples from rats. An approximately 5% increase of water content in t...

journal_title：Physics in medicine and biology

authors： Yamaguchi S,Fukushi Y,Kubota O,Itsuji T,Ouchi T,Yamamoto S

更新日期：2016-09-21 00:00:00

abstract：:We introduce a novel x-ray imaging approach that yields information about the local texture of structures smaller than the image pixel resolution inside an object. The approach is based on a recently developed x-ray dark-field imaging technique, using scattering from sub-micron structures in the sample. We show that t...

journal_title：Physics in medicine and biology

authors： Jensen TH,Bech M,Bunk O,Donath T,David C,Feidenhans'l R,Pfeiffer F

更新日期：2010-06-21 00:00:00

abstract：:We have developed an iterative method to correct axial and tangential patient motion occurring during tomographic acquisition. The method uses axial images reconstructed from the uncorrected projection images, which are then forward projected to form a basis for registering the original planar images and, in the proce...

journal_title：Physics in medicine and biology

authors： Lee KJ,Barber DC

更新日期：1998-01-01 00:00:00

abstract：:It has been reported that acoustic waves are generated when a high-energy pulsed proton beam is deposited in a small volume within tissue. One possible application of proton-induced acoustics is to get real-time feedback for intra-treatment adjustments by monitoring such acoustic waves. A high spatial resolution in ul...

journal_title：Physics in medicine and biology

authors： Kipergil EA,Erkol H,Kaya S,Gulsen G,Unlu MB

更新日期：2017-06-21 00:00:00

abstract：:In order to measure in vivo resistivity of tissues in the thorax, the possibility of combining anatomical data extracted from high-resolution images with multiple-electrode impedance measurements, a priori knowledge of the range of tissue resistivities, and a priori data on the instrumentation noise is assessed in thi...

journal_title：Physics in medicine and biology

authors： Eyüboğlu BM,Pilkington TC,Wolf PD

更新日期：1994-01-01 00:00:00

abstract：:An overview of the theory of 4D image reconstruction for emission tomography is given along with a review of the current state of the art, covering both positron emission tomography and single photon emission computed tomography (SPECT). By viewing 4D image reconstruction as a matter of either linear or non-linear par...

journal_title：Physics in medicine and biology

authors： Reader AJ,Verhaeghe J

更新日期：2014-11-21 00:00:00

abstract：:It is important to assess the viability of extremity soft tissues, as this component is often the determinant of the final outcome of fracture treatment. Microwave tomography (MWT) and sensing might be able to provide a fast and mobile assessment of such properties. MWT imaging of extremities possesses a complicated, ...

journal_title：Physics in medicine and biology

authors： Semenov S,Kellam J,Althausen P,Williams T,Abubakar A,Bulyshev A,Sizov Y

更新日期：2007-09-21 00:00:00

abstract：:In some medical procedures, it is difficult or impossible to maintain a line of sight for a guidance system. For such applications, people have begun to use electromagnetic trackers. Before a localizer can be effectively used for an image-guided procedure, a characterization of the localizer is required. The purpose o...

journal_title：Physics in medicine and biology

authors： Atuegwu NC,Galloway RL

更新日期：2008-08-21 00:00:00

abstract：:The inadequate visibility of microcalcifications-small calcium deposits that cue radiologists to early stages of cancer-is a major limitation in current designs of dedicated breast computed tomography (bCT). This limitation has previously been attributed to the constituent components, spatial resolution, and utilized ...

journal_title：Physics in medicine and biology

authors： Ghazi P

更新日期：2020-12-04 00:00:00

abstract：:This paper presents a computer simulation of photon interaction with collimator septa, which allows the point spread function of scintillation camera collimators to be calculated. The method simulates photon attenuation along their propagation direction in a determinist way. Using this simulation, the spatial resoluti...

journal_title：Physics in medicine and biology

authors： Gantet P,Esquerré JP,Danet B,Guiraud R

更新日期：1990-05-01 00:00:00

abstract：:A method to measure the detector-to-object distance from the images obtained with stationary high-spatial-resolution gamma-ray cameras for in vivo studies has been developed. It exploits the shift of the imaged object in the image plane, obtained at a certain tilt of the parallel-hole collimator. A linear dependence o...

journal_title：Physics in medicine and biology

authors： Uzunov N,Bello M,Boccaccio P,Moschini G,Bollini D,de Notaristefani F

更新日期：2006-05-07 00:00:00

abstract：:A method is presented for extraction of intra and inter fraction motion of seeds/markers within the patient from cone beam CT (CBCT) projection images. The position of the marker is determined on each projection image and fitted to a function describing the projection of a fixed point onto the imaging panel at differe...

journal_title：Physics in medicine and biology

authors： Marchant TE,Amer AM,Moore CJ

更新日期：2008-02-21 00:00:00

abstract：:We model the heterogeneous response to radiation of multicellular tumour spheroids assuming position- and volume-dependent radiosensitivity. We propose a method to calculate the overall radiosensitivity parameters to obtain the surviving fraction of tumours. A mathematical model of a spherical tumour with a hypoxic co...

journal_title：Physics in medicine and biology

authors： Horas JA,Olguin OR,Rizzotto MG

更新日期：2005-04-21 00:00:00

abstract：:The possible use of fluorescence bronchoscopy for localization of bronchogenic tumours at the carcinoma in situ stage has been investigated. The target lesion is 80 micrometer thick with a mass of 250 microgram, containing 250 pg of haematoporphyrin derivative. The injected haematoporphyrin-derivative is preferentiall...

journal_title：Physics in medicine and biology

authors： Profio AE,Doiron DR

更新日期：1977-09-01 00:00:00

abstract：:Accurate real-time prediction of respiratory motion is desirable for effective motion management in radiotherapy for lung tumor targets. Recently, nonparametric methods have been developed and their efficacy in predicting one-dimensional respiratory-type motion has been demonstrated. To exploit the correlation among v...

journal_title：Physics in medicine and biology

authors： Ruan D,Keall P

更新日期：2010-06-07 00:00:00