Abstract:
:The purpose of this study was to validate the accuracy and reliability of volume measurements obtained using three-dimensional (3D) thoracoscopic ultrasound (US) imaging. Artificial "tumours" were created by injecting a liquid agar mixture into spherical moulds of known volume. Once solidified, the "tumours" were implanted into the lung tissue in both a porcine lung sample ex vivo and a surgical porcine model in vivo. 3D US images were created by mechanically rotating the thoracoscopic ultrasound probe about its long axis while the transducer was maintained in close contact with the tissue. Volume measurements were made by one observer using the ultrasound images and a manual-radial segmentation technique and these were compared with the known volumes of the agar. In vitro measurements had average accuracy and precision of 4.76% and 1.77%, respectively; in vivo measurements had average accuracy and precision of 8.18% and 1.75%, respectively. The 3D thoracoscopic ultrasound can be used to accurately and reproducibly measure "tumour" volumes both in vivo and ex vivo.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Hornblower VD,Yu E,Fenster A,Battista JJ,Malthaner RAdoi
10.1088/0031-9155/52/1/007subject
Has Abstractpub_date
2007-01-07 00:00:00pages
91-106issue
1eissn
0031-9155issn
1361-6560pii
S0031-9155(07)31802-2journal_volume
52pub_type
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