Radionuclides and carrier molecules for therapy.

Abstract:

:Although radionuclide therapy has been around for a long time, this modality of cancer treatment has been limited mainly to the use of [32P]-phosphate and [131I]-sodium iodide. The last few years, however, have seen an increased interest in this area due to new developments of radionuclides and carrier molecules that may provide selective targeting of tumour sites. The potential of this technique can be further realized if the radionuclide is carefully selected to match both the localization of the carrier molecule and tumour morphology. This paper briefly reviews radionuclides in current use and potential candidates for targeted therapy. Decay characteristics, production methods and relevant chemical properties are discussed.

journal_name

Phys Med Biol

authors

Zweit J

doi

10.1088/0031-9155/41/10/004

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

1905-14

issue

10

eissn

0031-9155

issn

1361-6560

journal_volume

41

pub_type

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