Characterization of enzymatically induced degradation of articular cartilage using high frequency ultrasound.

abstract：:In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...

journal_title：Physics in medicine and biology

authors： Kaatee RS,Crezee J,Kanis AP,Lagendijk JJ,Levendag PC,Visser AG

更新日期：1997-06-01 00:00:00

abstract：:A near-field probe is described that enables high spatial resolution imaging with terahertz (THz) pulses. The spatial resolution capabilities of the system lie in the range of few microns and we demonstrate a resolution of 7 microm using broad-banded THz pulses with an intensity maximum near 0.5 THz. We present a stud...

journal_title：Physics in medicine and biology

authors： Federici JF,Mitrofanov O,Lee M,Hsu JW,Brener I,Harel R,Wynn JD,Pfeiffer LN,West KW

更新日期：2002-11-07 00:00:00

abstract：:Radionuclides which decay by electron capture accompanied by Auger electron cascades, or by beta emission are thought to be excessively damaging when incorporated into the molecular structure of mammalian cell nuclei and thereby pose a radiation hazard which is not assessable by conventional dosimetry. Survival data, ...

journal_title：Physics in medicine and biology

authors： Younis AR,Watt DE

更新日期：1989-07-01 00:00:00

abstract：:Electrical properties (EP), namely conductivity and permittivity, can provide endogenous contrast for tissue characterization. Using electrical property tomography (EPT), maps of EP can be generated from conventional MRI data. This report investigates the feasibility and accuracy of EPT at 21.1 T for multiple RF coils...

journal_title：Physics in medicine and biology

authors： Amouzandeh G,Mentink-Vigier F,Helsper S,Bagdasarian FA,Rosenberg JT,Grant SC

更新日期：2020-02-28 00:00:00

abstract：:New definitions of the absorbed dose conversion factors Clambda and CE are proposed. The absorbed dose in water is given by the product of absorbed dose conversion factor, exposure calibration factor, ionisation chamber reading, cap displacement correction factor and perturbation correction factor. At exposure calibra...

journal_title：Physics in medicine and biology

authors： Shiragai A

更新日期：1978-03-01 00:00:00

abstract：:Amorphous silicon electronic portal imaging devices (EPIDs) are used to perform routine quality control (QC) checks on the multileaf collimators (MLCs) at this centre. Presently, these checks are performed at gantry angle 0 degrees and are considered to be valid for all other angles. Since therapeutic procedures regul...

journal_title：Physics in medicine and biology

authors： Clarke MF,Budgell GJ

更新日期：2008-01-21 00:00:00

abstract：:Contrast-enhanced ultrasound (US) imaging is potentially applicable to the investigation of vascular disorders of the testis. We investigated the ability of two automated computer algorithms to analyse contrast-enhanced pulse inversion US data in a rabbit model of unilateral testicular ischaemia and to correctly deter...

journal_title：Physics in medicine and biology

authors： Thierman JS,Clement GT,Kalish LA,O'Kane PL,Frauscher F,Paltiel HJ

更新日期：2006-07-21 00:00:00

abstract：:Temporal regularization plays a critical role in cardiac gated dynamic SPECT reconstruction, of which the goal is to obtain an image sequence from a single acquisition which simultaneously shows both cardiac motion and tracer distribution change over the course of imaging (termed 5D). In our recent work, we explored t...

journal_title：Physics in medicine and biology

authors： Niu X,Yang Y,King MA

更新日期：2012-09-07 00:00:00

abstract：:Ion beam radiotherapy exploits the finite range of ion beams and the increased dose deposition of ions toward the end of their range in material. This results in high dose conformation to the target region, which can be further increased using scanning ion beams. The standard method for patient-plan verification in io...

journal_title：Physics in medicine and biology

authors： Martišíková M,Brons S,Hesse BM,Jäkel O

更新日期：2013-03-21 00:00:00

abstract：:The purpose of this study was to apply a novel method of multiscale echo texture analysis for distinguishing benign (hemangiomas) from malignant (hepatocellular carcinomas (HCCs) and metastases) focal liver lesions in B-mode ultrasound images. In this method, regions of interest (ROIs) extracted from within the lesion...

journal_title：Physics in medicine and biology

authors： Yoshida H,Casalino DD,Keserci B,Coskun A,Ozturk O,Savranlar A

更新日期：2003-11-21 00:00:00

abstract：:There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

journal_title：Physics in medicine and biology

authors： Renner F,Wulff J,Kapsch RP,Zink K

更新日期：2015-10-07 00:00:00

abstract：:We propose a method to compensate for six degree-of-freedom rigid motion in helical CT of the head. The method is demonstrated in simulations and in helical scans performed on a 16-slice CT scanner. Scans of a Hoffman brain phantom were acquired while an optical motion tracking system recorded the motion of the bed an...

journal_title：Physics in medicine and biology

authors： Kim JH,Nuyts J,Kyme A,Kuncic Z,Fulton R

更新日期：2015-03-07 00:00:00

abstract：:Exploiting the field response of magnetic tracers, magnetic particle imaging (MPI) allows direct, local quantification of the tracer concentration in bulk structures. Here, we investigated the use of characteristic field response functions to spatially resolve the absolute concentration of multiple nanoparticle specie...

journal_title：Physics in medicine and biology

authors： Han SH,Cho E,Lee DK,Cho G,Kim YR,Cho H

更新日期：2014-11-07 00:00:00

abstract：:Radiotherapy calculations often involve complex geometries such as interfaces between materials of vastly differing atomic number, such as lung, bone and/or air interfaces. Monte Carlo methods have been used to calculate accurately the perturbation effects of the interfaces. However, these methods can be computational...

journal_title：Physics in medicine and biology

authors： Gifford KA,Horton JL,Wareing TA,Failla G,Mourtada F

更新日期：2006-05-07 00:00:00

abstract：:Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provi...

journal_title：Physics in medicine and biology

authors： Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JG

更新日期：2000-10-01 00:00:00

abstract：:In nonlinear optimisation, using exact Hessian computations (full-Newton) hold superior convergence properties over quasi-Newton methods or gradient-based methods. However, for medium-scale problems, computing the Hessian can be computationally expensive and thus time-consuming. For solvers dedicated to a specific pro...

journal_title：Physics in medicine and biology

authors： van Haveren R,Breedveld S

更新日期：2019-08-14 00:00:00

abstract：:At present, only a correction factor for photon transmission, k(l), is systematically applied for the entrance diaphragm of free-air chamber standards for air kerma. In the present work, the Monte Carlo code PENELOPE is used to re-evaluate k(l) for the BIPM standards and new correction factors are calculated for photo...

journal_title：Physics in medicine and biology

authors： Burns DT,Kessler C

更新日期：2009-05-07 00:00:00

abstract：:Various lead attenuation techniques to determine the fast neutron sensitivity kU of a photon dosemeter are reviewed and a modified method is proposed to determine the kU value of a commercially available Geiger--Müller detector. The dependence on the 'effective' photon energy of the gamma-component of the mixed n--gam...

journal_title：Physics in medicine and biology

authors： Hough JH

更新日期：1979-07-01 00:00:00

abstract：:In this study, the quantitative accuracy of different attenuation correction strategies presently available for the High Resolution Research Tomograph (HRRT) was investigated. These attenuation correction methods differ in reconstruction and processing (segmentation) algorithms used for generating a micro-image from m...

journal_title：Physics in medicine and biology

authors： van Velden FH,Kloet RW,van Berckel BN,Molthoff CF,de Jong HW,Lammertsma AA,Boellaard R

更新日期：2008-01-07 00:00:00

abstract：:Radiation dose calculation using models of the human anatomy has been a subject of great interest to radiation protection, medical imaging, and radiotherapy. However, early pioneers of this field did not foresee the exponential growth of research activity as observed today. This review article walks the reader through...

journal_title：Physics in medicine and biology

authors： Xu XG

更新日期：2014-09-21 00:00:00

abstract：:Cylindrical homogenous phantoms for magnetic resonance (MR) elastography in biomedical research provide one way to validate an imaging systems performance, but the simplified geometry and boundary conditions can cloak complexity arising at tissue interfaces. In an effort to develop a more realistic gel tissue phantom ...

journal_title：Physics in medicine and biology

authors： Schwartz BL,Yin Z,Magin RL

更新日期：2016-09-21 00:00:00

abstract：:The performance of a light sharing and recirculation mechanism that allows the extraction of depth of interaction (DOI) are investigated in this paper, with a particular focus on timing. In parallel, a method to optimize the coincidence time resolution (CTR) of PET detectors by use of the DOI information is proposed a...

journal_title：Physics in medicine and biology

authors： Pizzichemi M,Polesel A,Stringhini G,Gundacker S,Lecoq P,Tavernier S,Paganoni M,Auffray E

更新日期：2019-08-07 00:00:00

abstract：:This paper introduces a novel compartmental model describing the excretion of 18F-fluoro-deoxyglucose (FDG) in the renal system and a numerical method based on the maximum likelihood for its reduction. This approach accounts for variations in FDG concentration due to water re-absorption in renal tubules and the increa...

journal_title：Physics in medicine and biology

authors： Garbarino S,Caviglia G,Sambuceti G,Benvenuto F,Piana M

更新日期：2014-05-21 00:00:00

abstract：:An x-ray fluorescence system with a synchrotron radiation source was used to quantify the levels of iron, copper and zinc in breast tissue specimens. Healthy tissue and breast carcinomas were investigated as an aid to understanding the mechanisms of breast cancer and as a possible complementary diagnostic tool. Eighty...

journal_title：Physics in medicine and biology

authors： Geraki K,Farquharson MJ,Bradley DA

更新日期：2002-07-07 00:00:00

abstract：:To monitor and strategically control energy deposition in magnetic resonance imaging (MRI), measured as a specific absorption rate (SAR), numerical methods using generic human models have been employed to estimate worst-case values. Radiofrequency (RF) sequences are therefore often designed conservatively with large s...

journal_title：Physics in medicine and biology

authors： Jin J,Liu F,Weber E,Crozier S

更新日期：2012-12-21 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00

abstract：:We combine two near-infrared diffuse optical techniques to study variations of blood flow, haemoglobin concentration, and blood oxygen saturation in the functioning rat brain. Diffuse correlation spectroscopy (or flowmetry) monitors changes in the cerebral blood flow, without the use of the principles of tracer cleara...

journal_title：Physics in medicine and biology

authors： Cheung C,Culver JP,Takahashi K,Greenberg JH,Yodh AG

更新日期：2001-08-01 00:00:00

abstract：:Earlier work on the dielectric properties of cryoprotectant agents is extended using a modified measuring cell and method of data reduction yielding results more efficiently over a temperature range from -75 to +25 degrees C at frequencies from 27 MHz to 3 GHz. Dimethyl sulphoxide and butanediol are investigated at lo...

journal_title：Physics in medicine and biology

authors： Evans S,bin Azeman A

更新日期：1998-10-01 00:00:00

abstract：:We propose a completely automated algorithm for the detection of the spinal centreline and the centres of vertebral bodies and intervertebral discs in images acquired by computed tomography (CT) and magnetic resonance (MR) imaging. The developed methods are based on the analysis of the geometry of spinal structures an...

journal_title：Physics in medicine and biology

authors： Stern D,Likar B,Pernus F,Vrtovec T

更新日期：2010-01-07 00:00:00

abstract：:Infrared measurements have been used to profile or image biological tissue, including human skin. Usually, analysis of such measurements has assumed that infrared absorption is due to water and collagen. Such an assumption may be reasonable for soft tissue, but introduction of exogenous agents into skin or the measure...

journal_title：Physics in medicine and biology

authors： Viator JA,Choi B,Peavy GM,Kimel S,Nelson JS

更新日期：2003-01-21 00:00:00