Methods for the inclusion of shallow marrow and adipose tissue in pathlength-based skeletal dosimetry.

Abstract:

:Distributions of linear pathlength measurements have been utilized in skeletal dosimetry of internally emitted short-range particles for over 30 years. This work reviews the methods for coupling these distributions to range-energy data. A revised methodology is presented for handling the insertion of the additional dosimetric target region (shallow marrow) and medium (adipose tissue) into the dosimetry algorithm. The methodology is shown to reduce the volume fraction of shallow marrow in the trabecular skeleton over existing methodologies. Finally, theoretical low and high-energy checkpoints are derived for use in checking the absorbed fraction and specific absorbed fraction results for a variety of source and target combinations.

journal_name

Phys Med Biol

authors

Jokisch DW,Rajon DA,Patton PW,Bolch WE

doi

10.1088/0031-9155/56/9/004

subject

Has Abstract

pub_date

2011-05-07 00:00:00

pages

2699-713

issue

9

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(11)72833-0

journal_volume

56

pub_type

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