The use of customized spreadsheets in radiation therapy.


:A number of radiation-therapy-related uses based on a commercially available spreadsheet program have been developed at our facility. The graphics and display capabilities inherent in these spreadsheet programs allow for concise visual results. The spreadsheets are used as an independent check for several types of radiation therapy dose calculations. External beam--a spreadsheet will verify the monitor units (MU) or time required to deliver a prescribed dose to a point on an isodose line as calculated by a commercial treatment planning system. Calibration--spreadsheet programs have been developed to perform the calculations necessary for the output calibration of cobalt and high-energy photon and electron beams according to the TG-21 protocol. The user must indicate which beam, electrometer, chamber, phantom material, temperature, pressure and depth of measurement that apply. Radiosurgery--the MU per arc is calculated based on the following: the average depth per arc as obtained from a commercial radiosurgery program, the collimator size, and the prescription dose. TBI--The patient's width is entered into the spreadsheet program, which then calculates the MU needed to deliver a prescribed dose to the midline.


Phys Med Biol


Balog JP,Sibata CH,Podgorsak MB,Shin KH




Has Abstract


1995-06-01 00:00:00












  • Factors affecting in vivo measurement precision and accuracy of 109Cd K x-ray fluorescence measurements.

    abstract::109Cd K x-ray fluorescence (XRF) measurement systems from two research centres were used to measure tibia lead content in a population (n = 530) of young adults. The group mean bone lead contents (+/-SEM) determined by McMaster University (n = 214) and the University of Maryland (n = 316) were 2.80 +/- 0.51 and 2.33 +...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: McNeill FE,Stokes L,Chettle DR,Kaye WE

    更新日期:1999-09-01 00:00:00

  • Dose distribution to spinal structures from intrathecally administered yttrium-90.

    abstract::Previous treatment of cerebrospinal fluid (CSF) malignancies by intrathecal administration of (131)I-radiolabelled monoclonal antibodies has led to the assumption that more healthy tissue will be spared when a pure beta-emitter such as (90)Y replaces (131)I. The purpose of this study is to compare and quantitatively e...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Mardirossian G,Hall M,Montebello J,Stevens P

    更新日期:2006-01-07 00:00:00

  • Automated sonographic evaluation of testicular perfusion.

    abstract::Contrast-enhanced ultrasound (US) imaging is potentially applicable to the investigation of vascular disorders of the testis. We investigated the ability of two automated computer algorithms to analyse contrast-enhanced pulse inversion US data in a rabbit model of unilateral testicular ischaemia and to correctly deter...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Thierman JS,Clement GT,Kalish LA,O'Kane PL,Frauscher F,Paltiel HJ

    更新日期:2006-07-21 00:00:00

  • Coupled thermo-electro-mechanical models for thermal ablation of biological tissues and heat relaxation time effects.

    abstract::Thermal ablation is a widely applied electrosurgical process in medical treatment of soft biological tissues. Numerical modeling and simulations play an important role in prediction of temperature distribution and damage volume during the treatment planning stage of associated therapies. In this contribution we report...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Singh S,Melnik R

    更新日期:2019-12-13 00:00:00

  • Determining clinical photon beam spectra from measured depth dose with the Cimmino algorithm.

    abstract::A method to determine the spectrum of a clinical photon beam from measured depth-dose data is described. At shallow depths, where the range of Compton-generated electrons increases rapidly with photon energy, the depth dose provides the information to discriminate the spectral contributions. To minimize the influence ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Bloch P,Altschuler MD,Bjärngard BE,Kassaee A,McDonough J

    更新日期:2000-01-01 00:00:00

  • The validation of tomotherapy dose calculations in low-density lung media.

    abstract::The dose-calculation accuracy of the tomotherapy Hi-Art II(R) (Tomotherapy, Inc., Madison, WI) treatment planning system (TPS) in the presence of low-density lung media was investigated. In this evaluation, a custom-designed heterogeneous phantom mimicking the mediastinum geometry was used. Gammex LN300 and balsa wood...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Chaudhari SR,Pechenaya OL,Goddu SM,Mutic S,Rangaraj D,Bradley JD,Low D

    更新日期:2009-04-21 00:00:00

  • Determination of mean ionization potential using magnetic resonance imaging for the reduction of proton beam range uncertainties: theory and application.

    abstract::The accurate determination of mean ionization potential (I m) has the potential to reduce range uncertainty based margins and therefore allow for more focal treatments in proton radiotherapy. Many methods have been proposed to reduce uncertainty in I m and stopping power ratios (SPR), each with varying degrees of accu...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Sudhyadhom A

    更新日期:2017-10-27 00:00:00

  • Phase contrast image guidance for synchrotron microbeam radiotherapy.

    abstract::Recent image guidance developments for preclinical synchrotron microbeam radiotherapy represent a necessary step for future clinical translation of the technique. Image quality can be further improved using x-ray phase contrast, which is readily available at synchrotron facilities. We here describe a methodology for p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Pelliccia D,Crosbie JC,Larkin KG

    更新日期:2016-08-21 00:00:00

  • Leakage of the Siemens 160 MLC multileaf collimator on a dual energy linear accelerator.

    abstract::Multileaf collimators (MLCs) have been in clinical use for many years and meanwhile are commonly used to deliver intensity-modulated radiotherapy (IMRT) beams. For this purpose it is important to know their dosimetric properties precisely, one of them being inter- and intraleaf leakage. The Siemens 160 MLC features a ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Klüter S,Sroka-Perez G,Schubert K,Debus J

    更新日期:2011-01-21 00:00:00

  • Additional factors for the estimation of mean glandular breast dose using the UK mammography dosimetry protocol.

    abstract::The UK and European protocols for mammographic dosimetry use conversion factors that relate incident air kerma to the mean glandular dose (MGD) within the breast. The conversion factors currently used were obtained by computer simulation of a model breast with a composition of 50% adipose and 50% glandular tissues by ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Dance DR,Skinner CL,Young KC,Beckett JR,Kotre CJ

    更新日期:2000-11-01 00:00:00

  • A compact and high sensitivity positron detector using dual-layer thin GSO scintillators for a small animal PET blood sampling system.

    abstract::For quantitative measurements of small animals such as mice or rats, a compact and high sensitivity continuous blood sampling detector is required because their blood sampling volume is limited. For this purpose we have developed and tested a new positron detector. The positron detector uses a pair of dual-layer thin ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Yamamoto S,Imaizumi M,Shimosegawa E,Kanai Y,Sakamoto Y,Minato K,Shimizu K,Senda M,Hatazawa J

    更新日期:2010-07-07 00:00:00

  • The measurement of silicon in a lung phantom--a comparison of two nuclear reactions for in vivo activation analysis.

    abstract::The amount of silica in the human lung may be estimated by measurement of silicon using in vivo neutron activation analysis. A pulsed, fast neutron beam, produced with a 2 MV Van de Graaff generator using the 2H + 2H reaction, was used to irradiate a Si-doped chest phantom in order to determine minimum detection limit...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Kacperek A,Ryde SJ,Evans CJ,Dutton J,Morgan WD,Sivyer A

    更新日期:1993-06-01 00:00:00

  • Comparative behaviour of the dynamically penalized likelihood algorithm in inverse radiation therapy planning.

    abstract::This paper presents a description of tests carried out to compare the behaviour of five algorithms in inverse radiation therapy planning: (1) The Dynamically Penalized Likelihood (DPL), an algorithm based on statistical estimation theory; (2) an accelerated version of the same algorithm: (3) a new fast adaptive simula...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Llacer J,Solberg TD,Promberger C

    更新日期:2001-10-01 00:00:00

  • List-mode-based reconstruction for respiratory motion correction in PET using non-rigid body transformations.

    abstract::Respiratory motion in emission tomography leads to reduced image quality. Developed correction methodology has been concentrating on the use of respiratory synchronized acquisitions leading to gated frames. Such frames, however, are of low signal-to-noise ratio as a result of containing reduced statistics. In this wor...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Lamare F,Ledesma Carbayo MJ,Cresson T,Kontaxakis G,Santos A,Le Rest CC,Reader AJ,Visvikis D

    更新日期:2007-09-07 00:00:00

  • Separating components of variation in measurement series using maximum likelihood estimation. Application to patient position data in radiotherapy.

    abstract::Maximum likelihood estimation (MLE) is presented as a statistical tool to evaluate the contribution of measurement error to any measurement series where the same quantity is measured using different independent methods. The technique was tested against artificial data sets; generated for values of underlying variation...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Sage JP,Mayles WP,Mayles HM,Syndikus I

    更新日期:2014-10-21 00:00:00

  • The effect of motion correction on pharmacokinetic parameter estimation in dynamic-contrast-enhanced MRI.

    abstract::A dynamic-contrast-enhanced magnetic resonance imaging (DCE-MRI) dataset consists of many imaging frames, often acquired both before and after contrast injection. Due to the length of time spent acquiring images, patient motion is likely and image re-alignment or registration is required before further analysis such a...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Melbourne A,Hipwell J,Modat M,Mertzanidou T,Huisman H,Ourselin S,Hawkes DJ

    更新日期:2011-12-21 00:00:00

  • K x-ray fluorescence measurements of bone lead concentration: the analysis of low-level data.

    abstract::K line x-ray fluorescence (KXRF) measurements of bone lead have emerged as a promising new biological marker of internal lead dose in epidemiological studies. Some disagreements exist, however, over the analysis of data at low levels of bone lead concentration. In this study, we performed 30 serial measurements on eac...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Kim R,Aro A,Rotnitzky A,Amarasiriwardena C,Hu H

    更新日期:1995-09-01 00:00:00

  • Distance-driven projection and backprojection in three dimensions.

    abstract::Projection and backprojection are operations that arise frequently in tomographic imaging. Recently, we proposed a new method for projection and backprojection, which we call distance-driven, and that offers low arithmetic cost and a highly sequential memory access pattern. Furthermore, distance-driven projection and ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: De Man B,Basu S

    更新日期:2004-06-07 00:00:00

  • Influence of beam characteristics and detector size in negative-pion dose studies.

    abstract::Dose calculations were performed for a tissue phantom irradiated by uniform circular beams of negative pions with an assumed gaussian momentum distribution. The mean momentum of the pions was varied from 104.4 to 171.5 MeV/c (mean range 5-20 cm in unit-density tissue) and the momentum spread from 0 to 5% of the mean. ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Hamm RN,Wright HA,Turner JE

    更新日期:1979-05-01 00:00:00

  • Pre- and post-natal exposure of children to EMF generated by domestic induction cookers.

    abstract::Induction cookers are a type of cooking appliance that uses an intermediate-frequency magnetic field to heat the cooking vessel. The magnetic flux density produced by an induction cooker during operation was measured according to the EN 62233 standard, and the measured values were below the limits set in the standard....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Kos B,Valič B,Miklavčič D,Kotnik T,Gajšek P

    更新日期:2011-10-07 00:00:00

  • An automated, fast and accurate registration method to link stranded seeds in permanent prostate implants.

    abstract::The geometry of a permanent prostate implant varies over time. Seeds can migrate and edema of the prostate affects the position of seeds. Seed movements directly influence dosimetry which relates to treatment quality. We present a method that tracks all individual seeds over time allowing quantification of seed moveme...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Westendorp H,Nuver TT,Moerland MA,Minken AW

    更新日期:2015-10-21 00:00:00

  • Comparison of risk of radiogenic second cancer following photon and proton craniospinal irradiation for a pediatric medulloblastoma patient.

    abstract::Pediatric patients who received radiation therapy are at risk of developing side effects such as radiogenic second cancer. We compared proton and photon therapies in terms of the predicted risk of second cancers for a 4 year old medulloblastoma patient receiving craniospinal irradiation (CSI). Two CSI treatment plans ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Zhang R,Howell RM,Giebeler A,Taddei PJ,Mahajan A,Newhauser WD

    更新日期:2013-02-21 00:00:00

  • Three-dimensional performance of a small-diameter positron emission tomograph.

    abstract::Recently, the initial 2D physical characterization of a small-diameter positron emission tomograph, designed specifically for scanning of small laboratory animals, was reported. The physical characteristics of the tomograph operating in 3D mode have now been measured and compared to those obtained in 2D mode. In 3D, t...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Bloomfield PM,Myers R,Hume SP,Spinks TJ,Lammertsma AA,Jones T

    更新日期:1997-02-01 00:00:00

  • Radionuclides and carrier molecules for therapy.

    abstract::Although radionuclide therapy has been around for a long time, this modality of cancer treatment has been limited mainly to the use of [32P]-phosphate and [131I]-sodium iodide. The last few years, however, have seen an increased interest in this area due to new developments of radionuclides and carrier molecules that ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章,评审


    authors: Zweit J

    更新日期:1996-10-01 00:00:00

  • Characterization of single α-tracks by photoresist detection and AFM analysis-focus on biomedical science and technology.

    abstract::The interactions between energetic ions and biological and/or organic target materials have recently attracted theoretical and experimental attention, due to their implications for detector and device technologies, and for therapeutic applications. Most of the attention has focused on detection of the primary ionizati...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Falzone N,Myhra S,Chakalova R,Hill MA,Thomson J,Vallis KA

    更新日期:2013-11-07 00:00:00

  • Modelling infrared temperature measurements: implications for laser irradiation and cryogen cooling studies.

    abstract::The use of thermographic techniques has increased as infrared detector technology has evolved and improved. For laser-tissue interactions, thermal cameras have been used to monitor the thermal response of tissue to pulsed and continuous wave irradiation. It is important to note that the temperature indicated by the th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Choi B,Pearce JA,Welch AJ

    更新日期:2000-02-01 00:00:00

  • Study of the PTW microLion chamber temperature dependence.

    abstract::The use of liquid ionization chambers in radiotherapy has grown during the past few years. While for air ionization chambers the k(TP) correction for air mass density due to pressure and temperature variations is well known, less work has been done on the case of liquid ionization chambers, where there is still the ne...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Gómez F,González-Castaño D,Díaz-Botana P,Pardo-Montero J

    更新日期:2014-06-07 00:00:00

  • Direct 4D reconstruction of parametric images incorporating anato-functional joint entropy.

    abstract::We developed an anatomy-guided 4D closed-form algorithm to directly reconstruct parametric images from projection data for (nearly) irreversible tracers. Conventional methods consist of individually reconstructing 2D/3D PET data, followed by graphical analysis on the sequence of reconstructed image frames. The propose...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Tang J,Kuwabara H,Wong DF,Rahmim A

    更新日期:2010-08-07 00:00:00

  • A hybrid scatter correction for 3D PET based on an estimation of the distribution of unscattered coincidences: implementation on the ECAT EXACT HR+.

    abstract::We implemented a hybrid scatter-correction method for 3D PET that combines two scatter-correction methods in a complementary way. The implemented scheme uses a method based on the discrimination of the energy of events (the estimation of trues method (ETM)) and an auxiliary method (the single scatter simulation method...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Ferreira NC,Trébossen R,Lartizien C,Brulon V,Merceron P,Bendriem B

    更新日期:2002-05-07 00:00:00

  • Measurement of calcium in sections of a human skeleton using a reactor spectrum-in vivo activation analysis technique.

    abstract::Factors influencing the precision of measuring changes in the calcium content of sections of bone, including vertebrae, using reactor neutrons for partial body in vivo activation analysis have been examined and quantified. These factors include (a) the choice of incidient neutron spectrum, (b) the uniformity of activa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章


    authors: Boddy K,Glaros D,Robertson I

    更新日期:1975-01-01 00:00:00