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Carboxyethyl gamma-aminobutyric acid, a polyamine derivative, improves the recovery of EBV-transformed lymphocytes.

Abstract：

:A polyamine derivative, carboxyethyl - Aminobutyric Acid (CEGABA), induces the formation of a large number of Epstein-Barr Virus (EBV) transformed lymphocytes, when added to the culture medium immediately after EBV infection. However, CEGABA shows only a moderate effect on the stability of EBV-transformed cell lines over time, and does not affect the growth of stabilized cell lines. It is possible that CEGABA acts on cells other than EBV transformed lymphocytes (in fact, after EBV infection all types of mononuclear cells from the blood are present in the culture) and indirectly promotes the growth of EBV transformed lymphocytes.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Cerino A,Bestagno M,Colonna M,Fussi F,Astaldi Ricotti GC

doi

10.1016/0006-291x(88)90718-8

subject

Has Abstract

pub_date

1988-02-15 00:00:00

pages

931-6

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(88)90718-8

journal_volume

150

pub_type

杂志文章

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