The APC regulator CDH1 is essential for the progression of embryonic cell cycles in Xenopus.

abstract：:Ceramide acts as a second messenger and modulates many cellular functions. This molecule can be produced by enzymatic digestion of sphingomyelin, a phospholipid which has been shown to be in high concentration in a chromatin phospholipidic fraction. In order to clarify whether chromatin sphingomyelin has a role in thi...

journal_title：Biochemical and biophysical research communications

authors： Albi E,Magni MP

更新日期：1997-07-09 00:00:00

abstract：OBJECT:The wall thickness of intracranial aneurysms (IAs) is heterogeneous. Although thinning of the IA wall is thought to contribute to IA rupture, the underlying mechanism remains poorly understood. Recently, imaging mass spectroscopy (IMS) has been used to reveal the distribution of phospholipids in vascular disease...

journal_title：Biochemical and biophysical research communications

authors： Ikedo T,Minami M,Kataoka H,Hayashi K,Nagata M,Fujikawa R,Yamazaki F,Setou M,Yokode M,Miyamoto S

更新日期：2018-01-01 00:00:00

abstract：:The green color of the hemolymph of last instar larvae of the corn earworm, Heliothis zea (Boddie), is caused by the appearance of a blue chromoprotein. This protein (Mr approximately 560,000) is composed of 4 subunits (Mr approximately 150,000). It contains 8.4% lipid and has an equilibrium density of 1.26 g/ml. This...

journal_title：Biochemical and biophysical research communications

authors： Haunerland NH,Bowers WS

更新日期：1986-01-29 00:00:00

abstract：:This article has been withdrawn at the request of the author(s). The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Biochemical and biophysical research communications

authors： Shi C,Wu J,Fu M,Zhang B,Wang J,Yang X,Chi Y

更新日期：2014-05-10 00:00:00

abstract：:Numerous phytochemicals are believed to have beneficial effects on human health. N-Coumaroyltyramine accumulates in plants in response to wounding and pathogen attack. Due to the scarcity of N-coumaroyltyramine, its biological activities have not been studied in human cells. In this study, N-coumaroyltyramine was chem...

journal_title：Biochemical and biophysical research communications

authors： Park JB,Schoene N

更新日期：2002-04-12 00:00:00

abstract：:After a peripheral nerve injury, the remaining Schwann cells undergo proliferation and adopt a migratory phenotype to prepare for the regeneration of nerves. Celsr2 has been reported to play an important role in the development and maintenance of the function of the nervous system. However, the role and mechanism of C...

journal_title：Biochemical and biophysical research communications

authors： Zhou X,Zhan Z,Tang C,Li J,Zheng X,Zhu S,Qi J

更新日期：2020-12-17 00:00:00

abstract：:Retinoids induce marked growth inhibition and neuritic differentiation in human neuroblastoma cells. Expression patterns of nuclear retinoic acid receptors (RAR) in embryonic and adult tissues suggests that RAR subtypes alpha, beta and gamma have tissue-specific functions. We have transfected a human neuroblastoma tum...

journal_title：Biochemical and biophysical research communications

authors： Cheung B,Hocker JE,Smith SA,Reichert U,Norris MD,Haber M,Stewart BW,Marshall GM

更新日期：1996-12-04 00:00:00

abstract：:The antiherpetic agent 9-beta-D-arabinofuranosyladenine (araA) needs to be phosphorylated to its 5'-triphosphate to be effective as an inhibitor of herpes simplex virus replication. Adenosine kinase and deoxycytidine kinase are assumed to convert araA to its 5'-monophosphate. We now found that araAMP is converted to i...

journal_title：Biochemical and biophysical research communications

authors： Balzarini J,De Clercq E

更新日期：1990-12-31 00:00:00

abstract：:The biological significance of isoprenoid compounds such as ubiquinones, prenols and sterols have been well established. The presence and biological function of the two quinones Q6 and Q8 in the cattle filarial parasite Setaria digitata have already been reported. Inhibition of the function of quinone was already show...

journal_title：Biochemical and biophysical research communications

authors： Kumari GA,Santhamma KR,Raj RK

更新日期：1994-11-30 00:00:00

abstract：:Fifteen pancreatic secretory proteins, including seven serine-endoproteinases (isoenzyme forms of trypsinogen, chymotrypsinogen and proelastase), four metallo-exoproteinases (isoenzymic forms of procarboxypeptidase A and procarboxypeptidase B), amylase, lipase, and two forms of carboxyl ester lipase were observed to a...

journal_title：Biochemical and biophysical research communications

authors： Freedman SD,Scheele GA

更新日期：1993-12-15 00:00:00

abstract：:Osteoclasts are hematopoietic cells essential for bone resorption. To understand the process of osteoclastogenesis, we have developed a culture system that employs a stromal cell line, in which differentiation of osteoclasts from single embryonic stem (ES) cells occurs. This culture, which did not require any cell pas...

journal_title：Biochemical and biophysical research communications

authors： Hemmi H,Okuyama H,Yamane T,Nishikawa S,Nakano T,Yamazaki H,Kunisada T,Hayashi S

更新日期：2001-01-19 00:00:00

abstract：:Cyclosporin accumulation was reduced by 50% or more in multidrug- resistant CHRC5 CHO cells with high levels of P-glycoprotein expression compared to drug sensitive AuxB1 CHO cells. This difference could be overcome by verapamil which is known to interact with P-glycoprotein and reverse multidrug resistance. The diffe...

journal_title：Biochemical and biophysical research communications

authors： Goldberg H,Ling V,Wong PY,Skorecki K

更新日期：1988-04-29 00:00:00

abstract：:The VLDL (very low-density lipoprotein) receptor is a peripheral lipoprotein receptor expressing in fatty acid active tissues abundantly. In the Balb/c fasting mice, VLDL receptor as well as LPL (lipoprotein lipase), FAT (fatty acid translocase)/CD36, H-FABP (heart-type fatty acid-binding protein), ACS (acyl-CoA synth...

journal_title：Biochemical and biophysical research communications

authors： Kamataki A,Takahashi S,Masamura K,Iwasaki T,Hattori H,Naiki H,Yamada K,Suzuki J,Miyamori I,Sakai J,Fujino T,Yamamoto TT

更新日期：2002-05-10 00:00:00

abstract：:We find that the low frequency Raman spectrum of Zn(II) metallothionein has a single prominent band at 138 cm-1 which is absent from the Raman spectrum of the metal-free protein. This feature is also found for Cd(II) binding to both of the independent metallothionein domains and the metallothionein from Neurospora cra...

journal_title：Biochemical and biophysical research communications

authors： Elgren TE,Wilcox DE

更新日期：1989-09-15 00:00:00

abstract：:An E. coli mutant deficient in organophosphonate biodegradation has been complemented with a cosmid library prepared from a BamHI partial digest of wild-type E. coli W3110. Mutant E. coli SL724, when transformed with cosmid pSL163 and plasmid pSL263, regained the ability to exploit ethylphosphonate as a sole source of...

journal_title：Biochemical and biophysical research communications

authors： Loo SH,Peters NK,Frost JW

更新日期：1987-10-14 00:00:00

abstract：:In Caenorhabditis elegans, the vulval induction is mediated by tyrosine kinase receptor/Ras signal transduction pathway composed of the lin-3, let-23, and let-60 products. In addition to these gene products, the lin-2, lin-7, and lin-10 products are also implicated in this pathway. Lin-2 encodes a MAGUK and lin-7 enco...

journal_title：Biochemical and biophysical research communications

authors： Ide N,Hirao K,Hata Y,Takeuchi M,Irie M,Yao I,Deguchi M,Toyoda A,Nishioka H,Mizoguchi A,Takai Y

更新日期：1998-02-13 00:00:00

abstract：:The family C G protein-coupled receptor (GPCR) T1R2 and T1R3 heterodimer functions as a broadly acting sweet taste receptor. Perception of sweet taste is a species-dependent physiological process. It has been widely reported that New World monkeys and rodents are not able to perceive some of the artificial sweeteners ...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Ha M,Meng XY,Khaleduzzaman M,Zhang Z,Li X,Cui M

更新日期：2012-10-19 00:00:00

abstract：:We have established that differing effects of alpha1-adrenergic receptor (AR) subtypes on cell proliferation are due to differential coupling to the Gs/cAMP pathway; thus, both alpha1A- and alpha1B-ARs couple to Gs, while alpha1D-AR does not. To identify the region responsible for this difference in subtype-specific G...

journal_title：Biochemical and biophysical research communications

authors： Shinoura H,Shibata K,Hirasawa A,Tanoue A,Hashimoto K,Tsujimoto G

更新日期：2002-11-22 00:00:00

abstract：:Adipose tissue is an active endocrine organ producing a variety of cytokines and chemokines, which may be involved in the deregulation of glucose and lipid homeostasis as well as in the inflammatory state observed in obesity. We have shown previously that differentiated human adipocytes secrete a variety of cytokines ...

journal_title：Biochemical and biophysical research communications

authors： Sell H,Dietze-Schroeder D,Eckardt K,Eckel J

更新日期：2006-05-12 00:00:00

abstract：:When treated with T3, P19 cells differentiate into ultrastructurally proven cardiac myocytes and express the cardiac ventricular specific marker ventricular myosin light chain 2V. This differentiation is irreversibly induced in culture during the first 48 hrs of exposure to T3. We studied the binding of P19-indigenous...

journal_title：Biochemical and biophysical research communications

authors： Rodriguez ER,Tan CD,Onwuta US,Parrillo JE

更新日期：1994-12-30 00:00:00

abstract：:Human natural killer enhancing factor genes (NKEF-A and B) share extensive homology with several genes from other organisms known to be induced by oxidative stress and to protect organisms and proteins from oxidative destruction. In this study, we have identified natural killer enhancing factor as an abundant protein ...

journal_title：Biochemical and biophysical research communications

authors： Shau H,Kim A

更新日期：1994-02-28 00:00:00

abstract：:The ability of phospholipase C inhibitors to inhibit Ca2+ channel stimulation and Ca2+ release from intracellular stores evoked by norepinephrine in single rat portal vein myocytes was investigated in the aim of identifying the type of phospholipase C involved in the transduction pathways activated by alpha 1A- and al...

journal_title：Biochemical and biophysical research communications

authors： Macrez-Leprêtre N,Morel JL,Mironneau J

更新日期：1996-01-05 00:00:00

abstract：:CD36 expressed on adipocytes is thought to function as a fatty acid transporter (FAT). Here we report that adipocytes can endocytose and lysosomally degrade OxLDL, mainly mediated by CD36. Mouse 3T3-L1 preadipocytes showed marked increase in uptake and degradation of (125)I-OxLDL during their differentiation to adipoc...

journal_title：Biochemical and biophysical research communications

authors： Kuniyasu A,Hayashi S,Nakayama H

更新日期：2002-07-12 00:00:00

abstract：:Permeability alteration of microvascular endothelia is a factor in the plasma leakage produced by dengue virus (DV) infection, and beta3 integrin plays central roles in maintaining capillary integrity and regulating vascular permeability. In this study, interaction between beta3 integrin and DV serotype 2 (DV2) was in...

journal_title：Biochemical and biophysical research communications

authors： Zhang JL,Wang JL,Gao N,Chen ZT,Tian YP,An J

更新日期：2007-05-11 00:00:00

abstract：:The neuropeptide Y (NPY) system is known as one of the major neural signaling pathways. NPY, produced by peripheral tissues including osteoblasts, is known to bind to the Y1 receptor. Recently, osteoblast-specific Y1 receptor knockout mice were developed and were found to have a high bone mass phenotype, indicating a ...

journal_title：Biochemical and biophysical research communications

authors： Kurebayashi N,Sato M,Fujisawa T,Fukushima K,Tamura M

更新日期：2013-10-04 00:00:00

abstract：:Studies were made on the mechanism of the effect of parathyroid hormone (PTH) on the activity of (Ca2++Mg2+)-ATPase, a membrane bound Ca2+-extrusion pump enzyme from the basolateral membranes (BLM) of canine kidney (Km for free Ca2+ = 1.3 X 10(-7) M, Vmax = 200 nmol Pi/mg/min). At 1 X 10(-7) M free Ca2+, both PTH (10(...

journal_title：Biochemical and biophysical research communications

authors： Itoh K,Morimoto S,Shiraishi T,Taniguchi K,Onishi T,Kumahara Y

更新日期：1988-01-15 00:00:00

abstract：:microRNAs (miRNAs) are short noncoding RNAs that function in RNA silencing and post-transcriptional regulation of gene expression. They play critical regulatory roles in many cardiovascular diseases, including ischemia-induced cardiac injury. Here, we report microRNA-22, highly expressed in the heart, can protect card...

journal_title：Biochemical and biophysical research communications

authors： Li G,Wang G,Ma L,Guo J,Song J,Ma L,Zhao X

更新日期：2016-09-23 00:00:00

abstract：:The retinoblastoma gene product (pRB) has been known to contain a sequence-nonspecific DNA binding activity. It is unknown whether pRB can recognize and bind to specific DNA sequences. We have recently identified a rat genomic DNA fragment, termed REC11, which can interact with rat Cdc37-related protein (RCdc37). In t...

journal_title：Biochemical and biophysical research communications

authors： Ozaki T,Sakiyama S

更新日期：1996-09-04 00:00:00

abstract：:Hydrogen sulfide (H2S), a gaseous signaling molecule produced by cystathionine γ-lyase (CSE) and cystathionine β-synthase (CBS), influences bone remodeling in many ways. Osteoclasts play an important role in bone remodeling during tooth movement induced by mechanical loading, which increases the rate of tooth movement...

journal_title：Biochemical and biophysical research communications

authors： Mo S,Hua Y

更新日期：2018-06-22 00:00:00

abstract：:Free fatty acids (FFAs) act as extracellular signaling molecules through binding to G-protein-coupled FFA receptors (FFARs). GPR120 and GPR40 are identified as FFARs for medium- and long-chain fatty acids. In the present study, we investigated roles of GPR120 and GPR40 in cellular functions of pancreatic cancer PANC-1...

journal_title：Biochemical and biophysical research communications

authors： Fukushima K,Yamasaki E,Ishii S,Tomimatsu A,Takahashi K,Hirane M,Fukushima N,Honoki K,Tsujiuchi T

更新日期：2015-09-25 00:00:00