Activation of the phosphorothionate insecticide parathion by rat brain in situ.

abstract：:In vivo electroporation and hydrodynamics-based gene delivery were utilized to test the effect of leptin gene transfer on food intake, and body and fat weights of mice. Gene transfer of pVRmob by electroporation caused a significant reduction in body weight compared with the control counterpart (p<0.05), although a le...

journal_title：Biochemical and biophysical research communications

authors： Xiang L,Murai A,Sugahara K,Yasui A,Muramatsu T

更新日期：2003-08-01 00:00:00

abstract：:Pluripotent human embryonic stem cells (hESCs) have the distinguishing feature of innate capacity to allow indefinite self-renewal. This attribute continues until specific constraints or restrictions, such as DNA methylation, are imposed on the genome, usually accompanied by differentiation. With the aim of utilizing ...

journal_title：Biochemical and biophysical research communications

authors： Yeo S,Jeong S,Kim J,Han JS,Han YM,Kang YK

更新日期：2007-08-03 00:00:00

abstract：:2'-Deoxycoformycin (dCF), a specific and potent inhibitor of adenosine deaminase, has demonstrated significant antitumor effect on lymphoid malignancies. The drug induced functional and morphologic differentiation of myeloid leukemia cells in combination with 2'-deoxyadenosine (dAd), but not dCF alone. NB4, a cell lin...

journal_title：Biochemical and biophysical research communications

authors： Niitsu N,Umeda M,Honma Y

更新日期：1997-09-08 00:00:00

abstract：:The role of recombination genes in the processing of DNA damaged by methlymethane sulfonate (MMS) was examined in an xth nth nfo strain of Escherichia coli K-12. Introduction of a recQ mutation did not increase the cell's sensitivity to MMS treatment. The presence of recF, recJ or recN mutation slightly increased the ...

journal_title：Biochemical and biophysical research communications

authors： Wang TC,Chang HY

更新日期：1991-10-31 00:00:00

abstract：:The octaheme cytochrome c3 (Mr 26000) from Desulfovibrio desulfuricans Norway was studied using cyclic voltammetry at the pyrolytic graphite electrode. The kinetics of reduction of the octaheme cytochrome c3 (Mr 26000) from D. desulfuricans Norway by the Ni-Fe-Se hydrogenase purified from the same organism was investi...

journal_title：Biochemical and biophysical research communications

authors： Haladjian J,Bianco P,Guerlesquin F,Bruschi M

更新日期：1991-08-30 00:00:00

abstract：:Regulation of gene expression in trypanosomatids is not yet well understood. Genes are organized in long polycistronic transcriptional units separated by intergenic regions that may contain the signaling information for nucleic acid processing. Poly-dinucleotides are frequent in these regions and have been proposed to...

journal_title：Biochemical and biophysical research communications

authors： Duhagon MA,Dallagiovanna B,Ciganda M,Ruyechan W,Williams N,Garat B

更新日期：2003-09-12 00:00:00

abstract：:Based on pseudo amino acid (PseAA) composition and a novel hybrid feature selection frame, this paper presents a computational system to predict the PPIs (protein-protein interactions) using 8796 protein pairs. These pairs are coded by PseAA composition, resulting in 114 features. A hybrid feature selection system, mR...

journal_title：Biochemical and biophysical research communications

authors： Liu L,Cai Y,Lu W,Feng K,Peng C,Niu B

更新日期：2009-03-06 00:00:00

abstract：:Escherichia coli with plasmid amplified expression of fumarate reductase was grown anaerobically on a medium containing fumarate and glycerol and investigated by electron paramagnetic resonance spectroscopy. Anaerobically harvested cells exhibit an EPR signal characteristic of a reduced [2Fe-2S] cluster. Anaerobic add...

journal_title：Biochemical and biophysical research communications

authors： Johnson MK,Morningstar JE,Cecchini G,Ackrell BA

更新日期：1985-09-16 00:00:00

abstract：:The small heat shock protein hsp27 is associated with aggressive tumor behavior in certain subsets of breast cancer patients. Previously we demonstrated that hsp27 overexpression in breast cancer cells increased in vitro and in vivo invasiveness, suggesting that hsp27 influences the metastatic process. To investigate ...

journal_title：Biochemical and biophysical research communications

authors： Hansen RK,Parra I,Hilsenbeck SG,Himelstein B,Fuqua SA

更新日期：2001-03-23 00:00:00

abstract：:Lymph node metastasis (LNM) is a critical cause for disease progression and treatment failure in cervical cancer. However, the mechanism underlying cervical cancer LNM remains unclear. In this study, HN1 was found to be dramatically upregulated in cervical cancer and patients with higher HN1 expression are more likely...

journal_title：Biochemical and biophysical research communications

authors： Chen J,Qiu J,Li F,Jiang X,Sun X,Zheng L,Zhang W,Li H,Wu H,Ouyang Y,Chen X,Lin C,Song L,Zhang Y

更新日期：2020-09-10 00:00:00

abstract：:A direct radioimmunoassay of atrial natriuretic factor (ANF) has been developed. The method uses a synthetic 26 amino-acid fragment (8-33 ANF) of the native peptide. Antibodies have been prepared in rabbits immunized with the peptide coupled to thyroglobulin. The radiolabelled tracer prepared by iodination according t...

journal_title：Biochemical and biophysical research communications

authors： Gutkowska J,Thibault G,Januszewicz P,Cantin M,Genest J

更新日期：1984-07-31 00:00:00

abstract：:The effect of reactive oxygen on cytosolic free calcium concentration [( Ca++]i) in pig aortic endothelial cells (ECs) was studied. Linoleate hydroperoxide (LHO) and superoxide radicals generated from xanthine with xanthine oxidase (X-XO) were used as sources of reactive oxygen. [Ca++]i in ECs was measured with quin 2...

journal_title：Biochemical and biophysical research communications

authors： Hirosumi J,Ouchi Y,Watanabe M,Kusunoki J,Nakamura T,Orimo H

更新日期：1988-04-15 00:00:00

abstract：:DmTTF is a Drosophila melanogaster mitochondrial DNA-binding protein which binds specifically to two homologous non-coding sequences located at the 3' ends of blocks of genes encoded on opposite strands. In order to test whether this protein acts as transcription termination factor, we assayed the capacity of DmTTF to...

journal_title：Biochemical and biophysical research communications

authors： Roberti M,Fernandez-Silva P,Polosa PL,Fernandez-Vizarra E,Bruni F,Deceglie S,Montoya J,Gadaleta MN,Cantatore P

更新日期：2005-05-27 00:00:00

abstract：:Although caffeine alters sleep in many animals, whether or not it affects mammalian circadian clocks remains unknown. Here, we found that incubating cultured mammalian cell lines, human osteosarcoma U2OS cells and mouse fibroblast NIH3T3 cells, with caffeine lengthened the period of circadian rhythms. Adding caffeine ...

journal_title：Biochemical and biophysical research communications

authors： Oike H,Kobori M,Suzuki T,Ishida N

更新日期：2011-07-08 00:00:00

abstract：:To study cellular and subcellular localization of TIMP-1, we constructed a cDNA which would express a chimeric protein, TIMP-1-EGFP, having the enhanced green fluorescent protein of the jelly fish Aequorea victoria fused to the carboxyl-terminus of TIMP-1. Chinese Hamster Ovary (CHO) cells were stably transfected with...

journal_title：Biochemical and biophysical research communications

authors： Ritter LM,Garfield SH,Thorgeirsson UP

更新日期：1999-04-13 00:00:00

abstract：:We have developed a new and rapid immunofluorescent method for visualisation of replicated regions on fixed DNA fibers. Using this method we have found in 5-fluorodeoxyuridine (FrdU)-blocked human cells distinct replication units covering about 60 kb of DNA and corresponding in size to single replicons or chromatin lo...

journal_title：Biochemical and biophysical research communications

authors： Tomilin N,Rosanov Yu,Zenin V,Bozhkov V,Vig B

更新日期：1993-01-15 00:00:00

abstract：:Heparin binding neurite-promoting factor (HBNF) is a highly basic 136 amino acid protein containing 10 cysteine residues. We have determined the redox status and the disulfide arrangement of the cysteine residues in HBNF from bovine brain and refolded human recombinant protein produced in E. coli. Our data indicate th...

journal_title：Biochemical and biophysical research communications

authors： Hulmes JD,Seddon AP,Decker MM,Böhlen P

更新日期：1993-04-30 00:00:00

abstract：:The coding sequence of type II phospholipase A2 from human placenta was cloned in a bovine papilloma virus-derived eukaryotic expression vector under the control of the metallothionein promoter. Stably transfected C127 mouse fibroblast lines were obtained with this vector. These transfected cells overexpressed a funct...

journal_title：Biochemical and biophysical research communications

authors： Pernas P,Masliah J,Olivier JL,Salvat C,Rybkine T,Bereziat G

更新日期：1991-08-15 00:00:00

abstract：:We have isolated and purified to apparent homogeneity a serum protein which appears to be a biological marker for active rheumatoid arthritis. The protein has been found in the sera in all 44 active rheumatoid arthritis patients thus far studied and is absent from, or present in undetected amounts, in sera from normal...

journal_title：Biochemical and biophysical research communications

authors： Rosano CL,Parhami N,Hurwitz C

更新日期：1985-05-16 00:00:00

abstract：:In this study we investigated the role of active site residues in the peroxidase activity of Orp1 (GPx3) using three different peroxide substrates. Using a structural homology model of the reduced form of Orp1, we identified Asn126 and Phe127 as evolutionarily conserved residues that line the back of the Orp1 active s...

journal_title：Biochemical and biophysical research communications

authors： Takanishi CL,Ma LH,Wood MJ

更新日期：2010-12-03 00:00:00

abstract：:Deregulated activation of protein tyrosine kinases, such as the epidermal growth factor receptor (EGFR) and Abl, is associated with human cancers including non-small cell lung cancer (NSCLC) and chronic myeloid leukemia (CML). Although inhibitors of such activated kinases have proved to be of therapeutic benefit in in...

journal_title：Biochemical and biophysical research communications

authors： Ozaki K,Kosugi M,Baba N,Fujio K,Sakamoto T,Kimura S,Tanimura S,Kohno M

更新日期：2010-01-22 00:00:00

abstract：:The activity of neutral sphingomyelinase (EC 3.1.4.12) in a plasma membrane enriched fraction was found to be increased in dexamethasone treated cells. The elevation of sphingomyelinase activity was blocked by cycloheximide indicating that protein synthesis was required for the steroid action. Ceramidase (EC3.5.1.23) ...

journal_title：Biochemical and biophysical research communications

authors： Ramachandran CK,Murray DK,Nelson DH

更新日期：1990-03-16 00:00:00

abstract：:The hepatic microsomal monooxygenase system was studied in hypophysectomized male rats exposed for 24 or 48 h to PB and/or TPA, an activator of kinase C. TPA attenuated basal and PB-induced levels of P450, aniline hydroxylase (ANH), ethylmorphine demethylase (EDM) and cytochrome c reductase. Hence, PB may effect induc...

journal_title：Biochemical and biophysical research communications

authors： Steele DF,Virgo BB

更新日期：1988-06-16 00:00:00

abstract：:Previously, we showed that several minor macromolecular glycolipids accounting for less than 5% of the lipoteichoic acid (LTA) fraction from Enterococcus hirae ATCC 9790 possess cytokine-inducing activity, whereas the purified LTA does not. In other words, the immunobiological activity of the LTA fraction reported in ...

journal_title：Biochemical and biophysical research communications

authors： Hashimoto M,Imamura Y,Morichika T,Arimoto K,Takeuchi O,Takeda K,Akira S,Aoyama K,Tamura T,Kotani S,Suda Y,Kusumoto S

更新日期：2000-06-24 00:00:00

abstract：:Antibodies subjected to SDS-polyacrylamide gel electrophoresis and transferred to nitrocellulose paper, have been found to retain the ability to bind specific antigen. This has been demonstrated for two groups of antibodies, directed to a) a large molecular weight glycoprotein of the human milk fat globule and b) huma...

journal_title：Biochemical and biophysical research communications

authors： Mather S,Taylor-Papadimitriou J

更新日期：1985-12-31 00:00:00

abstract：:Tissue factor (TF) is an initiation factor for blood coagulation and its expression is induced on endothelial cells during inflammatory or immune responses. We designed an antisense oligodeoxynucleotide (AS-1/TF) for rat TF and studied its effect on hepatic ischemic reperfusion injury. AS-1/TF was delivered intravenou...

journal_title：Biochemical and biophysical research communications

authors： Nakamura K,Kadotani Y,Ushigome H,Akioka K,Okamoto M,Ohmori Y,Yaoi T,Fushiki S,Yoshimura R,Yoshimura N

更新日期：2002-09-27 00:00:00

abstract：:ADP-ribosylation by cholera toxin of the guanine nucleotide binding regulatory protein (Gs) of rat liver membrane adenylate cyclase was inhibited by 0.1-1 mM MDL 12330A or 0.1-1 mM chlorpromazine. Basal as well as cholera toxin activated adenylate cyclase activity in liver membranes was also inhibited by the two drugs...

journal_title：Biochemical and biophysical research communications

authors： Bitonti AJ

更新日期：1984-04-30 00:00:00

abstract：:The cDNA encoding Mn peroxidase isozyme H4 from Phanerochaete chrysosporium was recombined into a baculovirus and heterologously expressed in Sf9 cells. The recombinant Mn peroxidase has the same molecular weight as the native enzyme as determined by SDS-PAGE and cross-reacts with a Mn peroxidase-specific antibody. Th...

journal_title：Biochemical and biophysical research communications

authors： Pease EA,Aust SD,Tien M

更新日期：1991-09-16 00:00:00

abstract：:The disruption of the intracellular Ca(2+) homeostasis of Leishmania mexicana represents a major target for the action of drugs, such as amiodarone and miltefosine. However, little is known about the mechanism of Ca(2+) entry to these cells. Here we show the presence of a Ca(2+) channel in the plasma membrane of these...

journal_title：Biochemical and biophysical research communications

authors： Benaim G,García-Marchán Y,Reyes C,Uzcanga G,Figarella K

更新日期：2013-01-18 00:00:00

abstract：:Bacteria belonging to the Burkholderia cepacia complex (BCC) are important opportunistic pathogens in patients with cystic fibrosis (CF). Since approximately 80% of the CF isolates examined produce exopolysaccharide (EPS), it was hypothesized that this EPS may play a role in the colonization and persistence of these b...

journal_title：Biochemical and biophysical research communications

authors： Moreira LM,Videira PA,Sousa SA,Leitão JH,Cunha MV,Sá-Correia I

更新日期：2003-12-12 00:00:00