Modification of soybean sucrose synthase by S-thiolation with ENOD40 peptide A.

abstract：:Signaling by stem cell factor and Kit, its receptor, play important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. Moreover, human and mouse embryonic stem cells express Kit transcripts. Stem cell factor exists as both a soluble and a membrane-bound glycoprotein while Kit...

journal_title：Biochemical and biophysical research communications

authors： Roskoski R Jr

更新日期：2005-12-23 00:00:00

abstract：:The nuclear receptors for heme, REV-ERBα and REV-ERBβ, play important roles in the regulation of metabolism and inflammation. Recently it was demonstrated that reduced REV-ERBα expression in hematopoetic cells in LDL receptor null mice led to increased atherosclerosis. We sought to determine if synthetic REV-ERB agoni...

journal_title：Biochemical and biophysical research communications

authors： Sitaula S,Billon C,Kamenecka TM,Solt LA,Burris TP

更新日期：2015-05-08 00:00:00

abstract：:Adult stem cells provide a promising alternative for the treatment of decompensated liver cirrhosis. Our previous study showed that peripheral blood monocytes (PBMCs) from decompensated liver cirrhosis could differentiate into hepatocyte-like cells in vitro. We here aimed to investigate the differential potential of t...

journal_title：Biochemical and biophysical research communications

authors： Yan L,Han Y,Wang J,Liu J,He Y,Wang H,Fan D

更新日期：2008-07-11 00:00:00

abstract：:Transforming growth factor (TGF)-beta1, a cytokine released into the cerebrospinal fluid (CSF) after intraventricular hemorrhage (IVH), stimulates the expression of the components of the extracellular matrix (ECM), which causes progressive ventricular dilatation by impaired CSF absorption. Matrix metalloproteinase-9 (...

journal_title：Biochemical and biophysical research communications

authors： Okamoto T,Takahashi S,Nakamura E,Nagaya K,Hayashi T,Fujieda K

更新日期：2009-06-12 00:00:00

abstract：:The properties of the Ca stores in the skinned fiber bundles of the guinea-pig taenia caeci were studied by a novel method to measure Ca released from the stores using a fluorescent Ca indicator, fura-2. It is found that the capacity of the Ca stores amounts some 170 mumoles/liter cell water. There are at least two Ca...

journal_title：Biochemical and biophysical research communications

authors： Iino M

更新日期：1987-01-15 00:00:00

abstract：:Lactoferrin (LF) is a multifunctional, iron-binding glycoprotein in mammalian secretions, such as breast milk, and has several beneficial effects for human health. However, how these effects are exerted at the cellular level is still largely unknown. In this study, we investigated the effects of LF on autophagy activi...

journal_title：Biochemical and biophysical research communications

authors： Aizawa S,Hoki M,Yamamuro Y

更新日期：2017-11-04 00:00:00

abstract：:We investigated the genomic organization of pancreatic zymogen granule membrane-associated protein GP2, a GPI-anchored protein exhibiting self-aggregation at acidic pH, in order to construct a gene-knockout mouse. Cloning and analysis of lambda clones encoding GP2 from 129 Svj mouse genomic DNA libraries showed that t...

journal_title：Biochemical and biophysical research communications

authors： Kobayashi K,Yanagihara K,Ishiguro K,Fukuoka S

更新日期：2004-09-17 00:00:00

abstract：:Vasodilator-stimulated phosphoprotein (VASP) is an actin regulatory protein that functions in adhesion and migration. In epithelial cells, VASP participates in cell-cell adhesion. At the molecular level, VASP drives actin bundling and polymerization. VASP activity is primarily regulated by phosphorylation. Three physi...

journal_title：Biochemical and biophysical research communications

authors： Thomson DM,Ascione MP,Grange J,Nelson C,Hansen MD

更新日期：2011-10-14 00:00:00

abstract：:Overexpression in Escherichia coli of the fdx4 gene from Aquifex aeolicus has allowed isolation and characterization of the first hyperthermophilic [2Fe-2S](Scys)(4) protein, a homodimer of M = 2 x 12.4 kDa with one [2Fe-2S] cluster per subunit. This protein is undamaged by heating to 100 degrees C for at least three ...

journal_title：Biochemical and biophysical research communications

authors： Chatelet C,Gaillard J,Pétillot Y,Louwagie M,Meyer J

更新日期：1999-08-11 00:00:00

abstract：:Recent evidence shows that Silver-Russell syndrome (SRS), the major functional deficit of which is limited growth, both intrauterine and postnatal, is due to a double dose of a gene within 7p11.2-p13 that is normally expressed exclusively from the maternal copy. Of the several growth-related genes in this chromosomal ...

journal_title：Biochemical and biophysical research communications

authors： McCann JA,Zheng H,Islam A,Goodyer CG,Polychronakos C

更新日期：2001-09-07 00:00:00

abstract：:The intrinsic GTPase activity of cellular protein p21ras is strongly increased by cytosolic GTPase activating protein (GAP). The activity of this enzyme has been shown to be inhibited by arachidonic acid. We report here that this inhibition is antagonized by the presence of 1-stearoyl, 2-arachidonoyl glycerol. This ef...

journal_title：Biochemical and biophysical research communications

authors： Homayoun P,Stacey DW

更新日期：1993-08-16 00:00:00

abstract：:Small ubiquitin-like modifiers (SUMOs) are proteins homologous to ubiquitin that possibly regulate intranuclear protein localization, nuclear transport, and ubiquitination. We examined patients of DRPLA, SCA1, MJD, and Huntington's disease and found that neurons in affected regions of the brain react strongly to SUMO-...

journal_title：Biochemical and biophysical research communications

authors： Ueda H,Goto J,Hashida H,Lin X,Oyanagi K,Kawano H,Zoghbi HY,Kanazawa I,Okazawa H

更新日期：2002-04-26 00:00:00

abstract：:Structural studies using 500 MHz 1H NMR spectroscopy on Bam H1 recognition site d(GGATCC)2 in solution at 19 degrees is reported. The resonances from the sugar ring and base protons have been assigned from the 2D-COSY and NOESY spectra. Analyses of the NOESY cross-peaks between the base protons H8/H6 and sugar protons...

journal_title：Biochemical and biophysical research communications

authors： Sarma MH,Dhingra MM,Gupta G,Sarma RH

更新日期：1985-08-30 00:00:00

abstract：:Sustained antibiotic release is important to prevent the infections after surgical treatments such as guided tissue regeneration (GTR). Electrospinning provides a simple way to fabricate nanofibers for drug delivery. In this study, a simple method to achieve sustained antibiotic release by introducing mesoporous silic...

journal_title：Biochemical and biophysical research communications

authors： Chen X,Xu C,He H

更新日期：2019-09-03 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Angiogenesis is reported to play a pivotal role in the occurrence, development and metastasis of HCC. The renin-angiotensin system (RAS) is involved in the regulation of angiogenesis. Here, based on the analysis of HCC datasets from Gene Expre...

journal_title：Biochemical and biophysical research communications

authors： Ye G,Qin Y,Lu X,Xu X,Xu S,Wu C,Wang X,Wang S,Pan D

更新日期：2015-03-27 00:00:00

abstract：:To understand the molecular mechanisms involved in preleukemia, the suppression subtractive hybridization method was used in a murine radiation-induced thymic lymphoma model. Seventeen mRNAs overexpressed in preleukemic thymuses were identified: mouse laminin binding protein (p40/37LBP), E25 protein, Rattus norvegicus...

journal_title：Biochemical and biophysical research communications

authors： Verlaet M,Deregowski V,Denis G,Humblet C,Stalmans MT,Bours V,Castronovo V,Boniver J,Defresne MP

更新日期：2001-04-27 00:00:00

abstract：:Ras proteins can be modified at their COOH-terminal cysteine in the motif Cys-Ali-Ali-Xaa by a farnesyl isoprenoid. This modification is essential for membrane association and biological activity of ras proteins. A similar COOH-terminal amino acid sequence, Cys-Xaa-Ali-Xaa, exists in the ras-related GTP-binding protei...

journal_title：Biochemical and biophysical research communications

authors： Didsbury JR,Uhing RJ,Snyderman R

更新日期：1990-09-14 00:00:00

abstract：:Chemotherapeutic efficacy is also regulated by the tumor microenvironment. IL-6 produced by TAMs and downstream IL-6/STAT3 signaling pathway is central regulator in chemotherapeutic response. The M2-like phenotype of TAMs is characterized by elevated iron uptake. Whether iron participates in chemo-resistance need to b...

journal_title：Biochemical and biophysical research communications

authors： Li J,He K,Liu P,Xu LX

更新日期：2016-06-24 00:00:00

abstract：:Galectins (gal), a family of soluble beta-galactoside-binding proteins present at the cell surface, are involved in cancer progression and metastasis. Here we investigated the expression of several galectins in normal (PrEC), benign (BPH-1), and malignant (LNCaP) prostate epithelial cells and found that all galectins,...

journal_title：Biochemical and biophysical research communications

authors： Ahmed H,Banerjee PP,Vasta GR

更新日期：2007-06-22 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma (PPAR-gamma) decreases the growth of certain cancer cells. In the present study, we found that six different human pancreatic cancer cell lines (AsPC-1, BxPC-3, Capan-2, HPAF-II, MIA PaCa-2, and PANC-1) expressed PPAR-gamma m-RNA and synthesized the protein. The endogen...

journal_title：Biochemical and biophysical research communications

authors： Eibl G,Wente MN,Reber HA,Hines OJ

更新日期：2001-09-21 00:00:00

abstract：:The molecular forms of endothelin (ET) related peptides were investigated in porcine brain by using high performance liquid chromatography coupled with three specific radioimmunoassays. ET-1 and its oxidized form were isolated and sequenced as in the case of porcine spinal cord. A very small amount of big ET-1 (1-39) ...

journal_title：Biochemical and biophysical research communications

authors： Shinmi O,Kimura S,Sawamura T,Sugita Y,Yoshizawa T,Uchiyama Y,Yanagisawa M,Goto K,Masaki T,Kanazawa I

更新日期：1989-10-16 00:00:00

abstract：:Polycystin-1 (PC1) is a membrane protein expressed in tubular epithelia of developing kidneys and in other ductal structures. Recent studies indicate this protein to be putatively important in regulating intracellular Ca(2+) levels in various cell types, but little evidence exists for kidney epithelial cells. Here we ...

journal_title：Biochemical and biophysical research communications

authors： Aguiari G,Campanella M,Manzati E,Pinton P,Banzi M,Moretti S,Piva R,Rizzuto R,del Senno L

更新日期：2003-02-14 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is an endothelial cell specific mitogen that induces angiogenesis in several pathological conditions. To block angiogenesis, soluble VEGF receptor can be used. In this study, we describe a method for high yield expression of soluble VEGF receptor 2 (sFlk-1) in a baculovirus ex...

journal_title：Biochemical and biophysical research communications

authors： Huang X,Gottstein C,Brekken RA,Thorpe PE

更新日期：1998-11-27 00:00:00

abstract：:Specific receptors for murine TNF have been identified in homogenates of rodent brain. These receptors are saturable and bind TNF with sufficient affinity to ensure occupancy by cytokine elaborated during infection. 125I-mTNF was detected in four specific complexes of Mr 130,000, 90,000, 66,000 and 60,000 after affini...

journal_title：Biochemical and biophysical research communications

authors： Kinouchi K,Brown G,Pasternak G,Donner DB

更新日期：1991-12-31 00:00:00

abstract：:Glycoprotein IIIb (GPIV, CD36) has been proposed as the platelet receptor for thrombospondin (TSP). We found two healthy blood donors, whose platelets were shown to be GPIIIb deficient. These platelets expressed endogeneous TSP as control platelets and their binding capacity for exogeneous TSP was the same. These resu...

journal_title：Biochemical and biophysical research communications

authors： Kehrel B,Kronenberg A,Schwippert B,Niesing-Bresch D,Niehues U,Tschöpe D,van de Loo J,Clemetson KJ

更新日期：1991-09-16 00:00:00

abstract：:The nuclear-mitochondrial stringent response was examined in isonuclear rho+, 21S rRNA-containing rho-, and rho o strains of S. cerevisiae. By 30 min after nutritional downshift, nuclear rDNA transcription falls to 15% of control levels congruently in all strains, as assayed via whole-cell RNA or by hybrid selection o...

journal_title：Biochemical and biophysical research communications

authors： McEntee CM,Cantwell R,Thomas LC,Hudson AP

更新日期：1989-10-16 00:00:00

abstract：:From the inner shoots of the chive Allium tuberosum, a single-chained protein with a molecular weight of 36 kDa and an N-terminal sequence manifesting resemblance to chitinases but lacking in cysteine residues characteristic of a cysteine-rich domain present in chitinases of other Allium species, was purified. The iso...

journal_title：Biochemical and biophysical research communications

authors： Lam YW,Wang HX,Ng TB

更新日期：2000-12-09 00:00:00

abstract：:We report here the interaction of melittin with ganglioside GM1 by steady-state fluorescence, one-dimensional (1)H NMR spectroscopy and molecular modeling. In the presence of GM1 the emission maximum of melittin is blue shifted and fluorescence quenching efficiencies of iodide and acrylamide are substantially reduced,...

journal_title：Biochemical and biophysical research communications

authors： Chatterjee C,Mukhopadhyay C

更新日期：2002-03-29 00:00:00

abstract：:An inhibitor against the egg beta-D-N-acetylglucosaminidase (GlcNAcase) was purified from the vitelline coat of eggs of the ascidian, Halocynthia roretzi. The purified inhibitor gave a single band with an apparent molecular mass of 70 kDa on SDS-PAGE under non-reducing conditions. The GlcNAcase inhibitor potently inhi...

journal_title：Biochemical and biophysical research communications

authors： Matsuura K,Sawada H,Yokosawa H

更新日期：1995-08-04 00:00:00

abstract：:Incubation of purified protein kinase C with H2O2 results in the generation of a persistently activated form of the enzyme which is no longer dependent on Ca2+ or lipid cofactors. This oxidative activation of purified protein kinase C requires added Fe2+ in the incubation medium. Treatment of the soluble fraction of h...

journal_title：Biochemical and biophysical research communications

authors： Palumbo EJ,Sweatt JD,Chen SJ,Klann E

更新日期：1992-09-30 00:00:00