Abstract：
:We studied mechanisms that mediate recognition of human erythrocytes (HRBC) and sheep erythrocytes (SRBC) by rat liver macrophages. We used an in vitro cell binding assay that allows spontaneous formation of cell contacts. Binding of HRBC to rat macrophages shows the following characteristics: inhibition studies with several monosaccharides and oligosaccharides yield complete inhibition of cell contacts with saccharides, which block the GalNAc/Gal-particle receptor on rat liver macrophages. We found the inhibition pattern: N-acetyl-D-galactosamine, lactose greater than D-galactose, D-fucose greater than L-fucose much greater than N-acetyl-D-glucosamine. Cell binding is dependent on the presence of calcium ions, but not influenced by heat-aggregated IgG or gangliosides. The inhibition pattern was the same after treatment of HRBC with neuraminidase. Therefore, binding of HRBC, as well as binding of neuraminidase-treated HRBC, is mediated by the GalNAc/Gal-particle receptor. Binding of SRBC is partly inhibited by galactose-related saccharides. Binding is also partly inhibited by heat-aggregated IgG, gangliosides, and L-fucose. Complete inhibition of cell contacts with SRBC is achieved by combination of all inhibitors. We therefore conclude that binding of SRBC is mediated by several different mechanisms, including the GalNAc/Gal-particle receptor. Binding of neuraminidase-treated SRBC, however, was found to be completely inhibited by saccharides, which block the GalNAc/Gal-particle receptor. We conclude that the GalNAc/Gal-particle receptor mediates or participates in recognition of non-self structures.
journal_name
Biol Celljournal_title
Biology of the cellauthors
Mohr M,Kolb H,Kolb-Bachofen V,Schlepper-Schäfer Jdoi
10.1111/j.1768-322x.1987.tb00558.xsubject
Has Abstractpub_date
1987-01-01 00:00:00pages
217-24issue
3eissn
0248-4900issn
1768-322Xjournal_volume
60pub_type
杂志文章abstract：:The distribution of viral RNA molecules in HeLa cells infected with adenovirus type 5 (Ad5) was determined by in situ hybridization at the ultrastructural level at an intermediate stage of nuclear transformation, when viral DNA synthetic activities were maximal but progeny viruses were still sparse. Transcription site...
journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1016/0248-4900(91)90060-z
更新日期：1991-01-01 00:00:00
abstract：:Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal degenerative diseases, characterized by the progressive death of rod and cone photoreceptors. A tremendous genetic heterogeneity is associated with the RP phenotype. Most mutations affect rods selectively and, through an unknown pathway, cause the...
journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：10.1016/j.biolcel.2004.01.006
更新日期：2004-05-01 00:00:00
abstract：:The diversity of microtubular networks was analyzed in quail oviduct and in Paramecium cells using conventional and confocal immunofluorescence as well as pre- and post-embedding EM immunocytochemistry with a variety of anti-tubulin antibodies. The 6-11B-1 monoclonal antibody, specific for the post-translational acety...
journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1016/0248-4900(91)90069-y
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND INFORMATION:CLEM (correlative live cell and electron microscopy) seeks to bridge the data acquired with different imaging strategies, typically between light microscopy and electron microscopy. It has been successfully applied in cell cultures, although its use in multicellular systems is hampered by difficu...
journal_title：Biology of the cell
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doi：10.1042/BC20090096
更新日期：2009-12-04 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1111/j.1768-322x.1985.tb00417.x
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND INFORMATION:Human gingival tissues are prone to hyperplasia under inflammatory stimuli. We have identified gingival tissue-specific mesenchymal stem cells (GMSCs) and found their functional change being correlated with drug-induced gingival hyperplasia. However, whether these cells exhibit characteristics of...
journal_title：Biology of the cell
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doi：10.1111/boc.201200064
更新日期：2013-06-01 00:00:00
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journal_title：Biology of the cell
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doi：
更新日期：1998-07-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1111/j.1768-322x.1987.tb00539.x
更新日期：1987-01-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1111/j.1768-322x.1986.tb00448.x
更新日期：1986-01-01 00:00:00
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doi：10.1016/s0248-4900(02)01185-1
更新日期：2002-05-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1111/j.1768-322x.1989.tb03013.x
更新日期：1989-01-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1042/BC20080060
更新日期：2009-04-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1111/boc.201400090
更新日期：2015-10-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：10.1042/BC20100144
更新日期：2011-06-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：10.1016/j.biolcel.2003.10.007
更新日期：2004-02-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：10.1016/s0248-4900(01)01126-1
更新日期：2001-09-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1042/BC20040125
更新日期：2005-09-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1016/0248-4900(91)90008-b
更新日期：1991-01-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1042/BC20070005
更新日期：2007-06-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1042/BC20090098
更新日期：2010-02-17 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:This review is concerned with the formation during ciliogenesis of centrioles and basal bodies, primarily in epithelial multi-ciliated cells from the developing vertebrate respiratory and reproductive tracts. During ciliated cell differentiation, in these as well as in other cell types, cilium formation is preceded by...
journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：10.1016/0248-4900(91)90075-x
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND INFORMATION:PCD (programmed cell death) is a common mechanism to remove unwanted and excessive cells from organisms. In several exocrine cell types, PCD mode of release of secretory products has been reported. The molecular mechanism of the release, however, is largely unknown. Our aim was to study the molec...
journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1042/BC20070168
更新日期：2009-02-01 00:00:00
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journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1016/s0248-4900(98)80018-x
更新日期：1998-06-01 00:00:00
abstract：:The dynamics of change in mitochondria-rich (MR) cells density in the skin epithelium of Bufo viridis was studied on skin biopsies taken in vivo, throughout experimental periods lasting up to 3 months. When the bathing solution contained Cl-, MR cells' density (Dmrc) greatly decreased. There was one exception, when th...
journal_title：Biology of the cell
pub_type： 杂志文章
doi：10.1016/0248-4900(96)85279-8
更新日期：1995-01-01 00:00:00
abstract：:A general feature of the cell adhesion molecules belonging to the immunoglobulin family (Ig-CAMs) is to display a modular structure that provides a framework for multiple binding sites for other recognition molecules. Among this family, F3/contactin is a glycan phosphatidyl-inositol (GPI)-anchored molecule expressed b...
journal_title：Biology of the cell
pub_type： 杂志文章,评审
doi：10.1016/s0248-4900(02)00006-0
更新日期：2002-10-01 00:00:00
