Lactoferrin Decreases the Intestinal Inflammation Triggered by a Soybean Meal-Based Diet in Zebrafish.

abstract：:Chlorogenic acid (CA) is a phenolic compound commonly found in human plant-based diets. CA is the main component of many traditional Chinese medicine preparations, and in recent years, it has been found to have hypoglycemic, hypolipidemic, anti-inflammatory, antioxidant, and other pharmacological properties. Specifica...

journal_title：Journal of immunology research

authors： Yan Y,Zhou X,Guo K,Zhou F,Yang H

更新日期：2020-05-28 00:00:00

abstract：Background:Diagnostic criteria for Sjögren's syndrome (SS) are continually being updated in pursuit of more precise and earlier diagnosis to prevent its complications. Owing to the high rate of false negative traditional serological markers, the need for better serological testing remains. Objective:To investigate the...

journal_title：Journal of immunology research

authors： Karakus S,Baer AN,Akpek EK

更新日期：2019-01-13 00:00:00

abstract：:Chemokine (C-X-C motif) ligand (CXCL)10 and other CXCR3 chemokines are involved in the pathogenesis of acute and "chronic hepatitis C virus (HCV) infection" (CHC). Here, we review the scientific literature about HCV and CXCL10. The combination of circulating CXCL10 and single nucleotide polymorphisms (SNPs) in IL-28B ...

journal_title：Journal of immunology research

authors： Ferrari SM,Fallahi P,Ruffilli I,Elia G,Ragusa F,Paparo SR,Patrizio A,Mazzi V,Colaci M,Giuggioli D,Ferri C,Antonelli A

更新日期：2019-08-08 00:00:00

abstract：:A derivative formula, DGBX, which is composed of three herbs (Radix astragali, Radix Angelicae sinensis, and Coptis chinensis Franch), is derived from a famous Chinese herbal formula, Danggui Buxue Tang (DBT) (Radix astragali and Radix Angelicae sinensis). We aimed to investigate the effects of DGBX on the regulation ...

journal_title：Journal of immunology research

authors： Zhou J,Li X,Deng P,Wei Y,Liu J,Chen M,Xu Y,Zhang D,Zhu L,Lou L,Dong B,Jin Q,Chai L

更新日期：2017-01-01 00:00:00

abstract：:Aims. In the present study, we aimed to assess the concentrations of IL-13 and IL-17 in serum of patients with early rheumatoid arthritis (eRA), the investigation of correlation between the concentrations of these cytokines and disease activity score, and the concentration of some autoantibodies and the evaluation of ...

journal_title：Journal of immunology research

authors： Siloşi I,Boldeanu MV,Cojocaru M,Biciuşcă V,Pădureanu V,Bogdan M,Badea RG,Avramescu C,Petrescu IO,Petrescu F,Siloşi CA

更新日期：2016-01-01 00:00:00

abstract：:RANKL (receptor activator of nuclear factor kappa-β ligand) and OPG (osteoprotegerin) are two proteins involved in bone remodelling. During the active phase of periodontal disease, an imbalance between the ratios of the two elements can be noticed. While the expression of RANKL is elevated compared with that of OPG, t...

journal_title：Journal of immunology research

authors： Teodorescu AC,Martu I,Teslaru S,Kappenberg-Nitescu DC,Goriuc A,Luchian I,Martu MA,Solomon SM,Mârțu S

更新日期：2019-04-28 00:00:00

abstract：:Propionibacterium acnes (P. acnes) is a gram-positive anaerobic bacillus present in normal human skin microbiota, which exerts important immunomodulatory effects, when used as heat- or phenol-killed suspensions. We previously demonstrated that heat-killed P. acnes or its soluble polysaccharide (PS), extracted from the...

journal_title：Journal of immunology research

authors： Squaiella-Baptistão CC,Teixeira D,Mussalem JS,Ishimura ME,Longo-Maugéri IM

更新日期：2015-01-01 00:00:00

abstract：:Chagas disease, or American trypanosomiasis, which is caused by the protozoan parasite Trypanosoma cruzi, is primarily a vector disease endemic in 21 Latin American countries, including Mexico. Although many vector control programs have been implemented, T. cruzi has not been eradicated. The development of an anti-T. ...

journal_title：Journal of immunology research

authors： Rodríguez-Morales O,Monteón-Padilla V,Carrillo-Sánchez SC,Rios-Castro M,Martínez-Cruz M,Carabarin-Lima A,Arce-Fonseca M

更新日期：2015-01-01 00:00:00

abstract：:Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening disease. However, there are only few epidemiologic studies of SJS/TEN from China. To analyze the clinical characteristics, causality, and outcome of treatment for SJS/TEN in China, we reviewed case reports of patients with SJS/TEN f...

journal_title：Journal of immunology research

authors： Yang SC,Hu S,Zhang SZ,Huang JW,Zhang J,Ji C,Cheng B

更新日期：2018-02-11 00:00:00

abstract：:Antiphospholipid syndrome (APS) is characterized by development of venous and/or arterial thrombosis and pregnancy morbidity. Biological criteria are the persistent presence of lupus anticoagulant (LA) and/or anti-cardiolipin (aCL) and/or anti-B2GP1 autoantibodies' positivity. The assays' performances are of crucial i...

journal_title：Journal of immunology research

authors： Sénant M,Rostane H,Fernani-Oukil F,Hosking F,Bellery F,Courchinoux A,Tartour E,Darnige L,Dragon-Durey MA

更新日期：2015-01-01 00:00:00

abstract：Objective:To evaluate the efficacy and safety of rituximab in multiple sclerosis in a clinical practice setting. Methods:Clinical data for all adult patients with multiple sclerosis (MS) treated with off-label rituximab at a single MS center in Lebanon between March 2008 and April 2017 were retrospectively collected f...

journal_title：Journal of immunology research

authors： Yamout BI,El-Ayoubi NK,Nicolas J,El Kouzi Y,Khoury SJ,Zeineddine MM

更新日期：2018-11-12 00:00:00

abstract：:It has been shown that rapamycin is able to significantly increase the expression of FoxP3 and suppress activity in induced Treg (iTreg) cells in vivo and in vitro. CD39 is a newly determined Treg marker that relates to cell suppression. Runx1, a regulator of FoxP3, controls the expression of adenosine deaminase (ADA)...

journal_title：Journal of immunology research

authors： Lu Y,Wang J,Gu J,Lu H,Li X,Qian X,Liu X,Wang X,Zhang F,Lu L

更新日期：2014-01-01 00:00:00

abstract：Objective:Systemic lupus erythematosus (SLE) is an autoimmune systemic disease and its pathogenesis has not yet been completely clarified. Patients with SLE show a deranged lipid metabolism, which can contribute to the immunopathogenesis of the disease and to the accelerated atherosclerosis. Resolvin D1 (RvD1), a produ...

journal_title：Journal of immunology research

authors： Navarini L,Bisogno T,Margiotta DPE,Piccoli A,Angeletti S,Laudisio A,Ciccozzi M,Afeltra A,Maccarrone M

更新日期：2018-10-21 00:00:00

abstract：:Regulatory T-cells (Tregs) are a very important subtype of lymphocytes when it comes to self-control in the human immunological system. Tregs are decisive not only in the protection against destruction of own tissues by autoimmune immunocompetent cells but also in the immunological answer to developing cancers. On the...

journal_title：Journal of immunology research

authors： Niedźwiecki M,Budziło O,Adamkiewicz-Drożyńska E,Pawlik-Gwozdecka D,Zieliński M,Maciejka-Kembłowska L,Szczepański T,Trzonkowski P

更新日期：2019-03-03 00:00:00

abstract：:A novel, simple, and reproducible method for cultivating pathological tissues obtained from human eyes during surgery was developed using viscoelastic material as a tissue adherent to facilitate cell attachment and expansion and calcium imaging of cultured cells challenged by mechanical and acetylcholine (ACh) stimula...

journal_title：Journal of immunology research

authors： Andjelic S,Lumi X,Veréb Z,Josifovska N,Facskó A,Hawlina M,Petrovski G

更新日期：2014-01-01 00:00:00

abstract：:Macrophages, a kind of innate immune cells, derive from monocytes in circulation and play a crucial role in the innate and adaptive immunity. Under the stimulation of the signals from local microenvironment, macrophages generally tend to differentiate into two main functional phenotypes depending on their high plastic...

journal_title：Journal of immunology research

authors： Peng H,Xian D,Liu J,Pan S,Tang R,Zhong J

更新日期：2020-07-28 00:00:00

abstract：:Reports suggesting a pathogenic role of autoantibodies directed against glutamic acid decarboxylase 65 (GAD65Abs) in cerebellar ataxias (CAs) are reviewed, and debatable issues such as internalization of antibodies by neurons and roles of epitopes are discussed. GAD65 is one of two enzymes that catalyze the conversion...

journal_title：Journal of immunology research

authors： Mitoma H,Manto M,Hampe CS

更新日期：2017-01-01 00:00:00

abstract：:Genetic and/or epigenetic changes provide antigen-derived diversity in neoplastic cells. Beside, these cells do not initiate immune response of host organisms. A variety of factors are responsible for the resistant to treatment, including individual variations in patients and somatic cell genetic differences in tumors...

journal_title：Journal of immunology research

authors： Witkowska M,Smolewski P

更新日期：2018-04-11 00:00:00

abstract：:Multiepitope peptide vaccine has some advantages over traditional recombinant protein vaccine due to its easy and fast production and possible inclusion of multiple protective epitopes of pathogens. However, it is usually poorly immunogenic and needs to conjugate to a large carrier protein. Peptides conjugated to a ce...

journal_title：Journal of immunology research

authors： Gu Y,Sun X,Huang J,Zhan B,Zhu X

更新日期：2020-01-08 00:00:00

abstract：:Background. Millions of people are infected with hepatitis C virus (HCV) worldwide and 30% spontaneously clear the infection. Reasons for HCV clearance without antiviral treatment are not well understood. Methods. Blood was collected for DNA analysis from patients with chronic HCV infection or evidence of spontaneous ...

journal_title：Journal of immunology research

authors： Waldron PR,Belitskaya-Lévy I,Chary A,Won J,Winters M,Monto A,Ryan J,Lazzeroni LC,Holodniy M

更新日期：2016-01-01 00:00:00

abstract：:Mast cells are unique tissue-resident immune cells that secrete a diverse array of biologically active compounds that can stimulate, modulate, or suppress the immune response. Although mounting evidence supports that mast cells are consistently infiltrating tumors, their role as either a driving or an opposite force f...

journal_title：Journal of immunology research

authors： Aponte-López A,Fuentes-Pananá EM,Cortes-Muñoz D,Muñoz-Cruz S

更新日期：2018-02-05 00:00:00

abstract：Background and Objectives:Pneumocystis pneumonia (PCP) is a common opportunistic infection in acquired immune deficiency syndrome (AIDS) patients that continues to result in a high mortality rate. To develop a better treatment strategy and improve PCP prognosis, a cohort study was conducted to evaluate the therapeutic ...

journal_title：Journal of immunology research

authors： Wang M,Lang G,Chen Y,Hu C,Guo Y,Tao R,Dong X,Zhu B

更新日期：2019-12-01 00:00:00

abstract：PURPOSES:To investigate the possible changes in B cell subsets and in B cell expression patterns of lipid rafts (LRs) and F-actin in patients with SLE and whether leflunomide treatment may have effect on these changes. METHODS:The B cell subsets and LRs expression were determined by flow cytometry and confocal microsc...

journal_title：Journal of immunology research

authors： Dong GF,Zhang X,He DN,Li L,Zhang GF

更新日期：2015-01-01 00:00:00

abstract：:Tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) gene encodes the A20 protein, an important negative feedback regulator of the nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) pathway. A coding TNFAIP3 variant, namely rs2230926, has been previously linked to B cell non-Hodgkin's lymphoma (...

journal_title：Journal of immunology research

authors： Nezos A,Gkioka E,Koutsilieris M,Voulgarelis M,Tzioufas AG,Mavragani CP

更新日期：2018-12-19 00:00:00

abstract：Background:Monocytic myeloid-derived suppressor cells (M-MDSCs) characterized with the phenotype of CD14+HLA-DRlow/- have attracted a lot of attention in the field of human tumor immunology. However, little is known about the roles of M-MDSCs in acute myeloid leukemia (AML) as opposed to their multiple roles in solid t...

journal_title：Journal of immunology research

authors： Wang H,Tao Q,Wang Z,Zhang Q,Xiao H,Zhou M,Dong Y,Zhai Z

更新日期：2020-12-21 00:00:00

abstract：:Amiselimod (MT-1303) is a novel and selective sphingosine 1-phosphate receptor-1 (S1P1) modulator with a more favorable cardiac safety profile than other S1P1 receptor modulators. In this study, we evaluated the effects of MT-1303 on the progression of lupus nephritis in two well-known murine systemic lupus erythemato...

journal_title：Journal of immunology research

authors： Sugahara K,Maeda Y,Shimano K,Murase M,Mochiduki S,Takemoto K,Kakimoto T,Utsumi H,Oshita K,Kataoka H

更新日期：2019-12-23 00:00:00

abstract：:We evaluated the association between anti-cyclic citrullinated peptide antibodies (anti-CCP) and anti-mutated citrullinated vimentin antibodies (anti-MCV) with the presence of extra-articular (ExRA) manifestations in 225 patients with rheumatoid arthritis (RA). Ninety-five patients had ExRA and 130 had no ExRA. There ...

journal_title：Journal of immunology research

authors： Gonzalez-Lopez L,Rocha-Muñoz AD,Ponce-Guarneros M,Flores-Chavez A,Salazar-Paramo M,Nava A,Cardona-Muñoz EG,Fajardo-Robledo NS,Zavaleta-Muñiz SA,Garcia-Cobian T,Gamez-Nava JI

更新日期：2014-01-01 00:00:00

abstract：:Cationic protein is a cytotoxic protein secreted by eosinophils and takes part in the damage of airway epithelium in asthma. Poly-L-arginine (PLA), a synthetic cationic protein, is widely used to mimic the biological function of the natural cationic protein in vitro. Previous studies demonstrated the damage of the air...

journal_title：Journal of immunology research

authors： Wang YN,Zhang LL,Fan XY,Wu SS,Zhang SQ

更新日期：2018-06-14 00:00:00

abstract：:The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. The main source of propolis in the northern temperate zone is poplar buds. However, there is limited research on the antidiabetic activity of poplar buds. In order to evaluate t...

journal_title：Journal of immunology research

authors： Peng S,Wei P,Lu Q,Liu R,Ding Y,Zhang J

更新日期：2018-09-18 00:00:00

abstract：:Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil, have changed its status as an emerging disease, but no vaccine or specific drug target is available yet. Our approach was to identify the epitope-based...

journal_title：Journal of immunology research

authors： Adhikari UK,Tayebi M,Rahman MM

更新日期：2018-10-08 00:00:00