Anti-cyclic citrullinated peptide (anti-CCP) and anti-mutated citrullinated vimentin (anti-MCV) relation with extra-articular manifestations in rheumatoid arthritis.

abstract：Objective:Systemic lupus erythematosus (SLE) is an autoimmune systemic disease and its pathogenesis has not yet been completely clarified. Patients with SLE show a deranged lipid metabolism, which can contribute to the immunopathogenesis of the disease and to the accelerated atherosclerosis. Resolvin D1 (RvD1), a produ...

journal_title：Journal of immunology research

authors： Navarini L,Bisogno T,Margiotta DPE,Piccoli A,Angeletti S,Laudisio A,Ciccozzi M,Afeltra A,Maccarrone M

更新日期：2018-10-21 00:00:00

abstract：Background:Diagnostic criteria for Sjögren's syndrome (SS) are continually being updated in pursuit of more precise and earlier diagnosis to prevent its complications. Owing to the high rate of false negative traditional serological markers, the need for better serological testing remains. Objective:To investigate the...

journal_title：Journal of immunology research

authors： Karakus S,Baer AN,Akpek EK

更新日期：2019-01-13 00:00:00

abstract：:The purpose of this study was to investigate the expression levels of the immune checkpoint proteins, programmed cell death-ligand 1 (PD-L1), B7-H3, B7-H4, and V-domain Ig suppressor of T cell activation (VISTA), as well as the significance thereof, in clear cell carcinoma (CCC) of the cervix (a rare histological subt...

journal_title：Journal of immunology research

authors： Zong L,Zhang Q,Zhou Y,Kong Y,Yu S,Chen J,Zhang Y,Xiang Y

更新日期：2020-04-03 00:00:00

abstract：:Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease. The aim of the study was to establish whether in patients with pSS without central nervous system (CNS) involvement, the function of the central portion of the sensory pathway can be challenged. In 33 patients with pSS without clinical features of CNS d...

journal_title：Journal of immunology research

authors： Dziadkowiak E,Sebastian A,Wieczorek M,Kusińska E,Waliszewska-Prosół M,Wiland P,Ejma M

更新日期：2018-04-05 00:00:00

abstract：:Collectin-12 (collectin placenta 1, CL-P1, or CL-12) is a newly identified pattern recognition molecule of the innate immune system. Recent evidences show that CL-12 plays important roles not only in innate immune protection against certain clinically important pathogens but also in scavenging of host molecules, leuko...

journal_title：Journal of immunology research

authors： Zhang J,Li A,Yang CQ,Garred P,Ma YJ

更新日期：2019-07-29 00:00:00

abstract：:Cutaneous melanoma is a significant immunogenic tumoral model, the most frequently described immune phenomenon being tumor regression, as a result of the interaction of tumoral antigens and stromal microenvironment. We present a retrospective cohort study including 52 cases of melanoma with regression. There were eval...

journal_title：Journal of immunology research

authors： Cioplea M,Nichita L,Georgescu D,Sticlaru L,Cioroianu A,Nedelcu R,Turcu G,Rauta A,Mogodici C,Zurac S,Popp C

更新日期：2020-10-23 00:00:00

abstract：:Diabetic retinopathy (DR) is an important cause of vision loss around the world, being the leading cause in the population between 20 and 60 years old. Among patients with DR, diabetic macular edema (DME) is the most frequent cause of vision impairment and represents a significant public health issue. Macular photocoa...

journal_title：Journal of immunology research

authors： Stefanini FR,Badaró E,Falabella P,Koss M,Farah ME,Maia M

更新日期：2014-01-01 00:00:00

abstract：:We investigated cytokine production and expression of degranulation marker CD107a after different strategies of hepatitis B virus (HBV) vaccination in human immunodeficiency virus-infected individuals, which were three doses of 20 μg (standard dose group), four doses of 20 μg (four doses group), or four doses of 40 μg...

journal_title：Journal of immunology research

authors： Chawansuntati K,Chaiklang K,Chaiwarith R,Praparattanapan J,Supparatpinyo K,Wipasa J

更新日期：2018-02-27 00:00:00

abstract：PURPOSES:To investigate the possible changes in B cell subsets and in B cell expression patterns of lipid rafts (LRs) and F-actin in patients with SLE and whether leflunomide treatment may have effect on these changes. METHODS:The B cell subsets and LRs expression were determined by flow cytometry and confocal microsc...

journal_title：Journal of immunology research

authors： Dong GF,Zhang X,He DN,Li L,Zhang GF

更新日期：2015-01-01 00:00:00

abstract：:Latent tuberculosis infection (LTBI) is evidence of immunological control of tuberculosis. Dormancy survival regulator (DosR) regulon-encoded proteins may have a role in the maintenance of LTBI. T cell responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR regulon-encoded proteins were found to be most frequent among...

journal_title：Journal of immunology research

authors： Kimuda SG,Nalwoga A,Levin J,Franken KL,Ottenhoff TH,Elliott AM,Cose S,Andia-Biraro I

更新日期：2017-01-01 00:00:00

abstract：Objective:To evaluate the efficacy and safety of rituximab in multiple sclerosis in a clinical practice setting. Methods:Clinical data for all adult patients with multiple sclerosis (MS) treated with off-label rituximab at a single MS center in Lebanon between March 2008 and April 2017 were retrospectively collected f...

journal_title：Journal of immunology research

authors： Yamout BI,El-Ayoubi NK,Nicolas J,El Kouzi Y,Khoury SJ,Zeineddine MM

更新日期：2018-11-12 00:00:00

abstract：:A derivative formula, DGBX, which is composed of three herbs (Radix astragali, Radix Angelicae sinensis, and Coptis chinensis Franch), is derived from a famous Chinese herbal formula, Danggui Buxue Tang (DBT) (Radix astragali and Radix Angelicae sinensis). We aimed to investigate the effects of DGBX on the regulation ...

journal_title：Journal of immunology research

authors： Zhou J,Li X,Deng P,Wei Y,Liu J,Chen M,Xu Y,Zhang D,Zhu L,Lou L,Dong B,Jin Q,Chai L

更新日期：2017-01-01 00:00:00

abstract：:Malaria continues being a high-impact disease regarding public health worldwide; the WHO report for malaria in 2018 estimated that ~219 million cases occurred in 2017, mostly caused by the parasite Plasmodium falciparum. The disease cost the lives of more than 400,000 people, mainly in Africa. In spite of great effort...

journal_title：Journal of immunology research

authors： Lambraño J,Curtidor H,Avendaño C,Díaz-Arévalo D,Roa L,Vanegas M,Patarroyo ME,Patarroyo MA

更新日期：2019-12-30 00:00:00

abstract：:Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate into mitochondria, l...

journal_title：Journal of immunology research

authors： Tian GA,Xu CJ,Zhou KX,Zhang ZG,Gu JR,Zhang XL,Wang YH

更新日期：2020-08-19 00:00:00

abstract：:The aim of this paper is to determine the modulatory effects of Lactobacillus acidophilus on the IL-23/Th17 immune axis in experimental colitis. DSS-induced mouse models of UC were to be saline, hormones, and different concentrations of Lactobacillus acidophilus intervention. The expression of interleukin- (IL-) 17, t...

journal_title：Journal of immunology research

authors： Chen L,Zou Y,Peng J,Lu F,Yin Y,Li F,Yang J

更新日期：2015-01-01 00:00:00

abstract：:Ovarian cancer is the most important cause of gynecological cancer-related mortality, with the majority of women presenting with advanced disease. Although surgery and chemotherapy can improve survival rates, it is necessary to integrate alternative strategies to improve the outcomes. Advances in understanding the rol...

journal_title：Journal of immunology research

authors： De Felice F,Marchetti C,Palaia I,Musio D,Muzii L,Tombolini V,Panici PB

更新日期：2015-01-01 00:00:00

abstract：:Considerable shortages in the supply of available organs continue to plague the field of solid organ transplantation. Despite changes in allocation, as well as the utilization of extended criteria and living donors, the number of patients waiting for organs continues to grow at an alarming pace. Xenotransplantation, c...

journal_title：Journal of immunology research

authors： Shah JA,Lanaspa MA,Tanabe T,Watanabe H,Johnson RJ,Yamada K

更新日期：2018-03-04 00:00:00

abstract：:Chlorogenic acid (CA) is a phenolic compound commonly found in human plant-based diets. CA is the main component of many traditional Chinese medicine preparations, and in recent years, it has been found to have hypoglycemic, hypolipidemic, anti-inflammatory, antioxidant, and other pharmacological properties. Specifica...

journal_title：Journal of immunology research

authors： Yan Y,Zhou X,Guo K,Zhou F,Yang H

更新日期：2020-05-28 00:00:00

abstract：:We recently have proved that excessive fecal DCA caused by high-fat diet may serve as an endogenous danger-associated molecular pattern to activate NLRP3 inflammasome and thus contributes to the development of inflammatory bowel disease (IBD). Moreover, the effect of DCA on inflammasome activation is mainly mediated t...

journal_title：Journal of immunology research

authors： Zhao S,Gong Z,Du X,Tian C,Wang L,Zhou J,Xu C,Chen Y,Cai W,Wu J

更新日期：2018-05-09 00:00:00

abstract：:Although cancer immunotherapy has shown significant promise in mediating efficacious responses, it remains encumbered by tumor heterogeneity, loss of tumor-specific antigen targets, and the regulatory milieu both regionally and systemically. Cross talk between the innate and adaptive immune response may be requisite t...

journal_title：Journal of immunology research

authors： Sayour EJ,Mitchell DA

更新日期：2017-01-01 00:00:00

abstract：:Systemic lupus erythematosus is characterized by dysregulated activation of T and B cells and autoantibodies to nuclear antigens and, in some cases, lipid antigens. Liposomes with nonbilayer phospholipid arrangements induce a disease resembling human lupus in mice, including IgM and IgG antibodies against nonbilayer p...

journal_title：Journal of immunology research

authors： Wong-Baeza C,Tescucano A,Astudillo H,Reséndiz A,Landa C,España L,Serafín-López J,Estrada-García I,Estrada-Parra S,Flores-Romo L,Wong C,Baeza I

更新日期：2015-01-01 00:00:00

abstract：:It has been shown that rapamycin is able to significantly increase the expression of FoxP3 and suppress activity in induced Treg (iTreg) cells in vivo and in vitro. CD39 is a newly determined Treg marker that relates to cell suppression. Runx1, a regulator of FoxP3, controls the expression of adenosine deaminase (ADA)...

journal_title：Journal of immunology research

authors： Lu Y,Wang J,Gu J,Lu H,Li X,Qian X,Liu X,Wang X,Zhang F,Lu L

更新日期：2014-01-01 00:00:00

abstract：:Molecular dynamics was used to simulate large molecules of the immune system (major histocompatibility complex class I, presented epitope, T-cell receptor, and a CD8 coreceptor.) To characterize the relative orientation and movements of domains local coordinate systems (based on principal component analysis) were gene...

journal_title：Journal of immunology research

authors： Schreiner W,Karch R,Ribarics R,Cibena M,Ilieva N

更新日期：2015-01-01 00:00:00

abstract：:Purified protein vaccines often require adjuvants for efficient stimulation of immune responses. There is no licensed mucosal adjuvant on the market to adequately boost the immune response to purified antigens for intranasal applications in humans. Bacterial outer membrane vesicles (OMV) are attractive candidates pote...

journal_title：Journal of immunology research

authors： Pritsch M,Ben-Khaled N,Chaloupka M,Kobold S,Berens-Riha N,Peter A,Liegl G,Schubert S,Hoelscher M,Löscher T,Wieser A

更新日期：2016-01-01 00:00:00

abstract：Aims:This study is aimed at exploring the relation between IL-33 single-nucleotide polymorphisms (SNPs) and the risk of systemic lupus erythematosus (SLE). Methods:SNPStats (online software) was used to test the Hardy-Weinberg equilibrium in controls. Generalized multifactor dimensionality reduction (GMDR) was adopted...

journal_title：Journal of immunology research

authors： Zhu X,Xie L,Qin H,Liang J,Yang Y,Xu J,Zhang T

更新日期：2019-03-11 00:00:00

abstract：:Mucosal surfaces in the airways and the gastrointestinal tract are critical for the interactions of the host with its environment. Due to their abundance at mucosal tissue sites and their powerful immunomodulatory capacities, the role of innate lymphoid cells (ILCs) and natural killer T (NKT) cells in the maintenance ...

journal_title：Journal of immunology research

authors： Nau D,Altmayer N,Mattner J

更新日期：2014-01-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer death worldwide due to its late diagnosis and poor outcome. Immunotherapy is becoming more and more encouraging and promising in lung cancer therapy. Myeloid-derived suppressor cells (MDSCs) are the main tumor suppressor factors, and the treatment strategy of targeting MDSCs ...

journal_title：Journal of immunology research

authors： Ma J,Xu H,Wang S

更新日期：2018-03-25 00:00:00

abstract：:Body fluids often contain freely circulating nucleic acids, many of which can be exploited as noninvasive tools for the diagnosis of cancer as well as for clinical prognostication. Identifying microRNAs (miRNAs) in subjects' blood with various malignancies means that they can serve as novel biomarkers for prostate can...

journal_title：Journal of immunology research

authors： Jin W,Fei X,Wang X,Chen F,Song Y

更新日期：2020-05-08 00:00:00

abstract：:Human respiratory syncytial virus (RSV) is a common and highly contagious viral agent responsible for acute lower respiratory infection in infants. This pathology characterized by mucus hypersecretion and a disturbed T cell immune response is one of the major causes of infant hospitalization for severe bronchiolitis. ...

journal_title：Journal of immunology research

authors： Drajac C,Laubreton D,Riffault S,Descamps D

更新日期：2017-01-01 00:00:00

abstract：:Severe aplastic anemia (SAA) is a rare disease characterized by severe pancytopenia and bone marrow failure. Most patients with AA respond to immunosuppressive therapy (IST), usually as antithymocyte globulin (ATG) and cyclosporine (CsA), but some relapse on CsA withdrawal or require long-term administration of CsA to...

journal_title：Journal of immunology research

authors： Ding S,Liang X,Zhang T,Fu R

更新日期：2020-10-17 00:00:00