Natural Language Processing Based Instrument for Classification of Free Text Medical Records.

abstract：:Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...

journal_title：BioMed research international

authors： Cui Y,Cai M,Stanley HE

更新日期：2017-01-01 00:00:00

abstract：:The aim of the study was to assess the prevalence of temporomandibular disorders (TMD) and oral parafunctions, as well as their correlation with psychoemotional factors in Polish university students. The research was conducted in a group of 456 students (N = 456). The examination form comprised of two parts: survey an...

journal_title：BioMed research international

authors： Wieckiewicz M,Grychowska N,Wojciechowski K,Pelc A,Augustyniak M,Sleboda A,Zietek M

更新日期：2014-01-01 00:00:00

abstract：:The number of RNA-Seq studies has grown in recent years. The design of RNA-Seq studies varies from very simple (e.g., two-condition case-control) to very complicated (e.g., time series involving multiple samples at each time point with separate drug treatments). Most of these publically available RNA-Seq studies are d...

journal_title：BioMed research international

authors： Kumar P,Halama A,Hayat S,Billing AM,Gupta M,Yousri NA,Smith GM,Suhre K

更新日期：2015-01-01 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a multifactorial disease characterized by progressive retinal ganglion cell death and visual field loss. It is known that alterations in intraocular pressure (IOP), blood pressure (BP), and ocular perfusion pressure (OPP) can play a significant role in the pathogenesis of the dise...

journal_title：BioMed research international

authors： Choi J,Kook MS

更新日期：2015-01-01 00:00:00

abstract：:Purpose. To evaluate correlation between tomographic gradation of keratoconus (KC) and its corresponding air-puff induced biomechanical response. Methods. Corneal tomography and biomechanics were measured with Scheimpflug imaging in 44 normal and 92 KC corneas. Deformation waveform was also analyzed with Fourier serie...

journal_title：BioMed research international

authors： Shetty R,Nuijts RM,Srivatsa P,Jayadev C,Pahuja N,Akkali MC,Sinha Roy A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 cells to the BALF colle...

journal_title：BioMed research international

authors： Cotogni P,Trombetta A,Muzio G,Maggiora M,Canuto RA

更新日期：2015-01-01 00:00:00

abstract：Purpose of Review:Transversus abdominis plane (TAP) block is a regional technique for analgesia of the anterolateral abdominal wall. This review highlights the nomenclature system and recent advances in TAP block techniques and proposes directions for future research. Recent Findings:Ultrasound guidance is now conside...

journal_title：BioMed research international

authors： Tsai HC,Yoshida T,Chuang TY,Yang SF,Chang CC,Yao HY,Tai YT,Lin JA,Chen KY

更新日期：2017-01-01 00:00:00

abstract：Background:The aim of this article is to present a short review of noninvasive, nonpharmacological treatment methods used in somatic illnesses that fall under the umbrella of approach called behavioral medicine. Methods:The narrative review method was applied in the study. Science paper databases, including PubMed, ha...

journal_title：BioMed research international

authors： Białkowska J,Juranek J,Wojtkiewicz J

更新日期：2020-11-03 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a severe and progressive disease, a key feature of which is pulmonary vascular remodeling. Growth factors, cytokines, and lipid mediators are involved in this remodeling process. Recent reports suggest that the peroxisome proliferator-activated receptors (PPARs) play important ...

journal_title：BioMed research international

authors： Liu G,Li X,Li Y,Tang X,Xu J,Li R,Hao P,Sun Y

更新日期：2013-01-01 00:00:00

abstract：:Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...

journal_title：BioMed research international

authors： Wen J,Yin P,Li L,Kang G,Ning G,Cao Y,Gao F,Su Y,Wu Y,Zhang X

更新日期：2020-04-15 00:00:00

abstract：:Birt-Hogg-Dube syndrome (BHD, OMIM#135150) is a rare disease in clinic; it is characterized by skin fibrofolliculomas, pulmonary cysts with an increased risk of recurrent pneumothorax, renal cysts, and renal neoplasms. Previous studies have demonstrated that variants in folliculin (FLCN, NM_144997) are mainly responsi...

journal_title：BioMed research international

authors： Liu L,Yang K,Wang X,Shi Z,Yang Y,Yuan Y,Guo T,Xiao X,Luo H

更新日期：2017-01-01 00:00:00

abstract：:Poly(ADP-ribose) polymerase (PARP) inhibitors have proven to be successful agents in inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached clinical trial testing for treatment in different cancers, and, recently, Olaparib (AZD2281) has gained both United States Food and Drug Admini...

journal_title：BioMed research international

authors： Murata S,Zhang C,Finch N,Zhang K,Campo L,Breuer EK

更新日期：2016-01-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy, is characterized by muscular wasting caused by dystrophin deficiency that ultimately ends in force reduction and premature death. In addition to primary genetic defect, several mechanisms contribute to DMD pathogenesis. Recently, antioxidan...

journal_title：BioMed research international

authors： Sitzia C,Farini A,Colleoni F,Fortunato F,Razini P,Erratico S,Tavelli A,Fabrizi F,Belicchi M,Meregalli M,Comi G,Torrente Y

更新日期：2015-01-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on lipid and glucose homeostasis. Previous study demonstrated that FGF21 might be one of the Sp1 target genes. However, the transcriptional role of Sp1 on FGF21 in adipose tissue and liver has not been reported. In this study, ...

journal_title：BioMed research international

authors： Chen S,Li H,Zhang J,Jiang S,Zhang M,Xu Y,Dong K,Yang Y,Fang Q,Jia W

更新日期：2017-01-01 00:00:00

abstract：:Mycobacterium avium subsp. paratuberculosis (Map) is the causative agent of a chronic intestinal inflammation in ruminants named Johne's disease or paratuberculosis and a possible etiopathological agent of human Crohn's disease (CD). Analysis of macrophage transcriptomes in response to Map infection is expected to pro...

journal_title：BioMed research international

authors： Abendaño N,Juste RA,Alonso-Hearn M

更新日期：2013-01-01 00:00:00

abstract：:Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequ...

journal_title：BioMed research international

authors： Lakusic N,Mahovic D,Kruzliak P,Cerkez Habek J,Novak M,Cerovec D

更新日期：2015-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder caused by selective loss of dopaminergic neurons in the substantia nigra pars compacta which leads to dysfunction of cerebral pathways critical for the control of movements. The diagnosis of PD is based on motor symptoms, such as bradykinesia, akinesia, muscular...

journal_title：BioMed research international

authors： Ciurleo R,Di Lorenzo G,Bramanti P,Marino S

更新日期：2014-01-01 00:00:00

abstract：:The different techniques and methods employed as well as the different quantitative and qualitative variables measured in order to objectify postural control are often chosen without taking into account the population studied, the objective of the postural test, and the environmental conditions. For these reasons, the...

journal_title：BioMed research international

authors： Paillard T,Noé F

更新日期：2015-01-01 00:00:00

abstract：:Within-litter birth weight variation in multiparous animals has become a big issue due to high incidence of low birth weight neonates, which gives rise to high preweaning mortality and morbidity. Foetus with various birth weights is the outcome of diverse embryos competence which is affected by oocyte quality. Glucosa...

journal_title：BioMed research international

authors： Feng C,Yuan T,Wang S,Liu T,Tao S,Han D,Wang J

更新日期：2020-01-08 00:00:00

abstract：:C-type lectins are multifunctional sugar-binding molecules expressed on dendritic cells (DCs) and macrophages that internalize antigens for processing and presentation. Macrophage galactose-type lectin 1 (MGL1) recognizes glycoconjugates expressing Lewis X structures which contain galactose residues, and it is selecti...

journal_title：BioMed research international

authors： Montero-Barrera D,Valderrama-Carvajal H,Terrazas CA,Rojas-Hernández S,Ledesma-Soto Y,Vera-Arias L,Carrasco-Yépez M,Gómez-García L,Martínez-Saucedo D,Becerra-Díaz M,Terrazas LI

更新日期：2015-01-01 00:00:00

abstract：:Kawasaki disease (KD) is an acute systemic vasculitis of childhood with prolonged fever, and the diagnosis of KD is mainly based on clinical criteria, which is prone to misdiagnosis with other febrile infectious (FI) diseases. Currently, there remain no effective molecular markers for KD diagnosis. In this study, we a...

journal_title：BioMed research international

authors： Zhong J,Huang Q,Wang Y,Gao H,Jia H,Fan J,Liang H

更新日期：2020-04-26 00:00:00

abstract：:This study is to investigate multiple chemotherapeutic agent- and radiation-related genetic biomarkers in locally advanced rectal cancer (LARC) patients following fluoropyrimidine-based concurrent chemoradiotherapy (CCRT) for response prediction. We initially selected 6 fluoropyrimidine metabolism-related genes (DPYD,...

journal_title：BioMed research international

authors： Huang MY,Wu CH,Huang CM,Chung FY,Huang CW,Tsai HL,Chen CF,Lin SR,Wang JY

更新日期：2013-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2018/2109865.]. ...

journal_title：BioMed research international

authors： You J,Chen W,Chen J,Zheng Q,Dong J,Zhu Y

更新日期：2019-12-13 00:00:00

abstract：:Diabetes mellitus is a major health problem that affects a patient's life quality throughout the world due to its worst complications. It was recognized that chronic hyperglycemia with oxidative stress was the major cause of male infertility. Echinacea purpurea ethanol extract (EE) contains phenolic acid and isobutyla...

journal_title：BioMed research international

authors： Mao CF,Zhang XR,Johnson A,He JL,Kong ZL

更新日期：2018-08-30 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2643862.]. ...

journal_title：BioMed research international

authors： Cheng LG,He W,Zhang HX,Song Q,Ning B,Li HZ,He Y,Lin S

更新日期：2017-01-01 00:00:00

abstract：:Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant activity, the other b...

journal_title：BioMed research international

authors： Won G,Jung JH,Sohn EJ,Park JE,Kim H,Lee HJ,Shim BS,Kim SH

更新日期：2020-02-07 00:00:00

abstract：:The search for effective methods of myocardial cytoprotection against ischemia is the most significant issue in modern cardiology and cardiac surgery. Glucocorticoids are deemed very strong modulators of inflammatory response and thus can potentially protect heart muscle from postreperfusion injury and myocardial isch...

journal_title：BioMed research international

authors： Kuropka P,Dobrzyński M,Gamian A,Gostomska-Pampuch K,Kuryszko J,Całkosiński I

更新日期：2017-01-01 00:00:00

abstract：:Lipids have been widely used as main constituents in various drug delivery systems, such as liposomes, solid lipid nanoparticles, nanostructured lipid carriers, and lipid-based lyotropic liquid crystals. Among them, lipid-based lyotropic liquid crystals have highly ordered, thermodynamically stable internal nanostruct...

journal_title：BioMed research international

authors： Chen Y,Ma P,Gui S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the effects of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, and sedation and to find out its adverse effects in children having lower abdominal surgery. METH...

journal_title：BioMed research international

authors： Saylan S,Eroglu A,Dohman D

更新日期：2014-01-01 00:00:00

abstract：:The availability of an active substance through the skin depends basically on two consecutive steps: the release of this substance from the vehicle and its subsequent permeation through the skin. Hence, studies on the specific properties of vehicles, such as their rheological behavior, are of great interest in the fie...

journal_title：BioMed research international

authors： Isaac VL,Chiari-Andréo BG,Marto JM,Moraes JD,Leone BA,Corrêa MA,Ribeiro HM

更新日期：2015-01-01 00:00:00