EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus.

abstract：:Methiocarb, an aromatic-alkyl sulfide insecticide was enzymatically oxidized into its sulfoxide by microsomes from soybean cotyledons. No further oxidation into sulfone was detected. Distribution of the sulfoxidase activity was studied in soybean seedlings and found maximal in cotyledons. Subcellular fractionation of ...

journal_title：Biochemical and biophysical research communications

authors： Blee E,Durst F

更新日期：1986-03-28 00:00:00

abstract：:Voltage-dependent anion channel (VDAC) is a multi-functional channel protein in the mitochondrial outer membrane of all eukaryotes. It is involved in extensive physiological and pathophysiological processes. However there is only scant information about VDAC in mammalian reproduction, fertility and development in the ...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Zhang W,Wang Z

更新日期：2010-07-09 00:00:00

abstract：:Nowadays, connexin (Cx) 36 is considered the sole gap junction protein expressed in pancreatic beta cells. In the present research we investigated the expression of Cx30.2 mRNA and protein in mouse pancreatic islets. Cx30.2 mRNA and protein were identified in isolated islet preparations by qRT-PCR and Western blot, re...

journal_title：Biochemical and biophysical research communications

authors： Coronel-Cruz C,Hernández-Tellez B,López-Vancell R,López-Vidal Y,Berumen J,Castell A,Pérez-Armendariz EM

更新日期：2013-09-06 00:00:00

abstract：:Protein folding continues to be an important biophysical topic in molecular biology. We report the parameters for successfully refolding the guanylyl cyclase core of the ANP receptor, an allosteric homodimeric enzyme. Urea was a better chaotropic solvent than guanidine HCl, and physiological salt concentrations and pH...

journal_title：Biochemical and biophysical research communications

authors： Thorpe DS,Niu S,Morkin E

更新日期：1996-07-25 00:00:00

abstract：:Two blind source separation methods (Independent Component Analysis and Non-negative Matrix Factorization), developed initially for signal processing in engineering, found recently a number of applications in analysis of large-scale data in molecular biology. In this short review, we present the common idea behind the...

journal_title：Biochemical and biophysical research communications

authors： Zinovyev A,Kairov U,Karpenyuk T,Ramanculov E

更新日期：2013-01-18 00:00:00

abstract：:Chikungunya is a severe disease that results from infection with the chikungunya virus (CHIKV), an arbovirus. Thus, we (1) explored a new approach to combining previously researched drugs that have shown the potential to inhibit CHIKV infection; and (2) demonstrated the antiviral effects of (-)-Epigallocatechin-3-gall...

journal_title：Biochemical and biophysical research communications

authors： Lu JW,Hsieh PS,Lin CC,Hu MK,Huang SM,Wang YM,Liang CY,Gong Z,Ho YJ

更新日期：2017-09-23 00:00:00

abstract：:A series of C-terminal linear peptides of endothelin (ET)-1 and their N alpha-succinyl (Suc) analogs were synthesized and their binding affinities for the two subtypes of ET receptor, ETA and ETB, in porcine lung membranes were examined. Among the synthetic analogs, Suc-[Glu9,Ala11,15]-ET-1(8-21), IRL 1620, was the mo...

journal_title：Biochemical and biophysical research communications

authors： Takai M,Umemura I,Yamasaki K,Watakabe T,Fujitani Y,Oda K,Urade Y,Inui T,Yamamura T,Okada T

更新日期：1992-04-30 00:00:00

abstract：:Regenerating gene (Reg) I has been identified as a regenerative/proliferative factor for pancreatic islet cells. We examined Reg I expression in the regenerating liver of a rat model that had been administered 2-acetylaminofluorene and treated with 70% partial hepatectomy (2-AAF/PH model), where hepatocyte and cholang...

journal_title：Biochemical and biophysical research communications

authors： Wang J,Koyota S,Zhou X,Ueno Y,Ma L,Kawagoe M,Koizumi Y,Okamoto H,Sugiyama T

更新日期：2009-03-13 00:00:00

abstract：:Several studies support a role for the multiple tumor suppressor gene (MTS1) in the malignant progression of different tumor types. In this study we have examined the status of the MTS1 gene in a variety of non-astrocytic tumors of the central nervous system. It was not possible, using multiplex PCR with primers for M...

journal_title：Biochemical and biophysical research communications

authors： Walker DG,Duan W,Kaye AH,Lavin MF

更新日期：1995-06-15 00:00:00

abstract：:Using recombinant DNA technology, the NH2 and COOH terminal domains of the human Factor VIII molecule were co-expressed in baby hamster kidney 21 (BHK21) cells using the vaccinia virus system. Procoagulant activity was detectable in cell supernatants, thus suggesting that the central portion present in the FVIII prote...

journal_title：Biochemical and biophysical research communications

authors： Pavirani A,Meulien P,Harrer H,Dott K,Mischler F,Wiesel ML,Mazurier C,Cazenave JP,Lecocq JP

更新日期：1987-05-29 00:00:00

abstract：INTRODUCTION:Multiple myeloma (MM) remains incurable due to high rates of relapse after various treatment regimens. WEE1 is a cell cycle related gene that regulates the G2/M checkpoint and promotes cell cycle suspension for consequent DNA repair. To date, there are clinical studies for the evaluation of WEE1 inhibitors...

journal_title：Biochemical and biophysical research communications

authors： Barbosa RSS,Dantonio PM,Guimarães T,de Oliveira MB,Fook Alves VL,Sandes AF,Fernando RC,Colleoni GWB

更新日期：2019-11-12 00:00:00

abstract：:Exogenous angiogenin undergoes rapid nuclear translocation in cultured human umbilical artery endothelial cells at 37 degrees C but not at 4 degrees C. Treatment of cells with colchicine, nocodazole and taxol, which disrupt the microtubule system, does not affect the nuclear translocation process of angiogenin, sugges...

journal_title：Biochemical and biophysical research communications

authors： Li R,Riordan JF,Hu G

更新日期：1997-09-18 00:00:00

abstract：:The cDNA for subunit d of rat mitochondrial H(+)-ATP synthase was cloned from a brain cDNA library. The protein contains internally repeat structures that have sequences similar to those of other ATP-related proteins. The antibodies raised against the protein A-subunit d fusion protein expressed in E. coli specificall...

journal_title：Biochemical and biophysical research communications

authors： Motojima K,Imanaka T

更新日期：1992-02-14 00:00:00

abstract：:The effect of several agents known to interact with muscarinic acetylcholine receptors on the release of choline from slices of rat corpus striatum into the incubation medium has been investigated. The amount of released choline was increased if choline, acetylcholine, or oxotremorine had been added to the incubation ...

journal_title：Biochemical and biophysical research communications

authors： Dolezal V,Tucek S

更新日期：1984-05-16 00:00:00

abstract：:Previous structural and mutational studies of bovine pancreatic deoxyribonuclease I (bpDNase I) have demonstrated that the active site His134 and His252 played critical roles in catalysis. In our present study, mutations of these two His residues to Gln, Ala or Gly reduced the DNase activity by a factor of four to fiv...

journal_title：Biochemical and biophysical research communications

authors： Chen WJ,Lai PJ,Lai YS,Huang PT,Lin CC,Liao TH

更新日期：2007-01-19 00:00:00

abstract：:Spin-trapping of superoxide ion, O2-, which is produced from two different sources (OH(-)-DMSO and xanthine-xanthine oxidase systems), was investigated by use of a water-soluble, notroso-aromatic spin trap, sodium 3,5-dibromo-4-nitrosobenzene-sulfonate (DBNBS). It was found that O2- from all sources was easily trapped...

journal_title：Biochemical and biophysical research communications

authors： Ozawa T,Hanaki A

更新日期：1986-04-29 00:00:00

abstract：:Using PAGE--Autoradioblotting technique we have characterized an E--FABP in human epidermal cells that is distinct from liver-, heart-, intestine- and adipose tissue-FABPs. FABP radiobinding analysis was performed directly on protein extracts without prior partial purification. E-FABP has a Mr of approximately 15 kDa ...

journal_title：Biochemical and biophysical research communications

authors： Siegenthaler G,Hotz R,Chatellard-Gruaz D,Jaconi S,Saurat JH

更新日期：1993-01-29 00:00:00

abstract：:The association of endogenous synenkephalin and met-enkephalin containing peptides with the membrane of bovine chromaffin granules and physicochemical characteristics of this association were studied. The associated materials were only released at a non physiological pH range and this effect was enhanced with growing ...

journal_title：Biochemical and biophysical research communications

authors： Ase A,Vindrola O,Aloyz R,Inés M,Vida R,Finkielman S,Nahmod V

更新日期：1989-02-15 00:00:00

abstract：:Tetrahymena p85 is localized to the presumptive division plane before division furrow formation; its molecular weight in SDS-polyacrylamide gel electrophoresis differs in wild-type and temperature-sensitive cell-division-arrest mutant cdaA1 cells. At the restrictive temperature, p85 localization and division furrow fo...

journal_title：Biochemical and biophysical research communications

authors： Gonda K,Nishibori K,Ohba H,Watanabe A,Numata O

更新日期：1999-10-14 00:00:00

abstract：:Pancreatic adenocarcinoma is currently one of the leading causes of cancer-related death worldwide. The high rate of mortality in pancreatic cancer patients is due to the inability to detect early-stage disease and the disease being highly refractory to therapy. Gemcitabine has been the standard chemotherapy for advan...

journal_title：Biochemical and biophysical research communications

authors： Ahn HM,Kim DG,Kim YJ

更新日期：2020-06-25 00:00:00

abstract：:Purified m beta-acrosin catalysed amidolysis in vitro of several p-nitroanilides with C-terminal arginine residues. alpha 1-proteinase inhibitor inhibited amidolysis catalysed by the enzyme. This effect of alpha 1-Proteinase inhibitor was not prevented by pre-incubation of the enzyme with heparin or any other glycosam...

journal_title：Biochemical and biophysical research communications

authors： Long WF,Williamson FB

更新日期：1983-11-30 00:00:00

abstract：:A novel nucleic acid analogue (2Cl-C.OXT-A) significantly stimulated tube formation of human umbilical endothelial cells (HUVEC). Its maximum potency at 100muM was stronger than that of vascular endothelial growth factor (VEGF), a positive control. At this concentration, 2Cl-C.OXT-A moderately stimulated proliferation...

journal_title：Biochemical and biophysical research communications

authors： Tsukamoto I,Sakakibara N,Maruyama T,Igarashi J,Kosaka H,Kubota Y,Tokuda M,Ashino H,Hattori K,Tanaka S,Kawata M,Konishi R

更新日期：2010-09-03 00:00:00

abstract：:Axonal transport of mitochondria is a microtubule-associated movement. Microtubule-mitochondria interactions were studied in vitro using organelles isolated from rat brain. Thanks to the ligand blotting method we were able to show two mitochondrial membrane proteins with apparent molecular masses of 30 kDa and 60 kDa ...

journal_title：Biochemical and biophysical research communications

authors： Rendon A,Filliol D,Jancsik V

更新日期：1987-12-16 00:00:00

abstract：:Internal and environmental cues, including ambient temperature changes, regulate the timing of flowering in plants. Arabidopsis miR156 represses flowering and plays an important role in the regulation of temperature-responsive flowering. However, the molecular basis of miR156 processing at lower temperatures remains l...

journal_title：Biochemical and biophysical research communications

authors： Kim HE,Kim W,Lee AR,Jin S,Jun AR,Kim NK,Lee JH,Ahn JH

更新日期：2017-03-18 00:00:00

abstract：:The olfactomedin-domain has been first identified in olfactomedin, an extracellular matrix protein of the olfactory neuroepithelium. Members of this extracellular domain-family have since been shown to be present in several metazoan proteins, such as latrophilins, myocilins, and noelins, but their biological function ...

journal_title：Biochemical and biophysical research communications

authors： Nagy I,Trexler M,Patthy L

更新日期：2003-03-14 00:00:00

abstract：:maf is a family of oncogenes, originally identified from the avian oncogenic retrovirus AS42, which encodes a nuclear bZip transcription factor protein. It has been reported that maf family genes have critical roles in embryological development and cellular differentiation. In this study, the distribution of maf-1 gen...

journal_title：Biochemical and biophysical research communications

authors： Imaki J,Onodera H,Tsuchiya K,Imaki T,Mochizuki T,Mishima T,Yamashita K,Yoshida K,Sakai M

更新日期：2000-06-16 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) Tax-induced activation of nuclear factor-kappaB (NFkappaB) is thought to play a critical role in T-cell transformation and onset of adult T-cell leukemia. However, the molecular mechanism of the Tax-induced NFkappaB activation remains unknown. One of the mitogen-activated pr...

journal_title：Biochemical and biophysical research communications

authors： Gohda J,Irisawa M,Tanaka Y,Sato S,Ohtani K,Fujisawa J,Inoue J

更新日期：2007-05-25 00:00:00

abstract：:P19 embryonal carcinoma (EC) cells are pluripotent stem cells and have numerous morphological and biochemical properties in common with embryonic stem (ES) cells. However, P19 cells differentiate very ineffectively as embryoid bodies (EBs) without the specific chemical inducers whereas ES cells exhibit spontaneous dif...

journal_title：Biochemical and biophysical research communications

authors： Morikawa K,Ikeda N,Hisatome I,Shirayoshi Y

更新日期：2013-02-08 00:00:00

abstract：:Molecular dynamics simulation method is used to assess the contribution of a disease-associated salt bridge in the early stages of the conformational rearrangement of human prion protein upon Arg208-->His mutation, which causes Creutzfeldt-Jakob disease. Previous investigations have suggested that the breakage of this...

journal_title：Biochemical and biophysical research communications

authors： Bamdad K,Naderi-Manesh H

更新日期：2007-12-28 00:00:00

abstract：:To clarify the role of hepatocyte growth factor (HGF) in embryonic lung development, organoids from fetal rat lung were cultured in collagen gels with or without HGF antisense oligonucleotides. Cyst-like structures formed within 24 h in organoids isolated from fetuses after 14 days' gestation, but this was abolished b...

journal_title：Biochemical and biophysical research communications

authors： Itakura A,Kurauchi O,Morikawa S,Okamura M,Furugori K,Mizutani S

更新日期：1997-12-08 00:00:00