Abstract:
:Using recombinant DNA technology, the NH2 and COOH terminal domains of the human Factor VIII molecule were co-expressed in baby hamster kidney 21 (BHK21) cells using the vaccinia virus system. Procoagulant activity was detectable in cell supernatants, thus suggesting that the central portion present in the FVIII protein (domain B) is not required for FVIII function.
journal_name
Biochem Biophys Res Communjournal_title
Biochemical and biophysical research communicationsauthors
Pavirani A,Meulien P,Harrer H,Dott K,Mischler F,Wiesel ML,Mazurier C,Cazenave JP,Lecocq JPdoi
10.1016/0006-291x(87)91311-8subject
Has Abstractpub_date
1987-05-29 00:00:00pages
234-40issue
1eissn
0006-291Xissn
1090-2104pii
0006-291X(87)91311-8journal_volume
145pub_type
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