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Oxidation of an organosulfur xenobiotic by microsomes from soybean cotyledons.

Abstract：

:Methiocarb, an aromatic-alkyl sulfide insecticide was enzymatically oxidized into its sulfoxide by microsomes from soybean cotyledons. No further oxidation into sulfone was detected. Distribution of the sulfoxidase activity was studied in soybean seedlings and found maximal in cotyledons. Subcellular fractionation of cotyledons homogenates indicated that the activity was almost entirely associated with the microsomal fraction. Sulfoxidation of methiocarb did not require cofactors such as NAD(P)H. Nevertheless, the sulfoxidase did not act as a peroxidase.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Blee E,Durst F

doi

10.1016/0006-291x(86)91016-8

subject

Has Abstract

pub_date

1986-03-28 00:00:00

pages

922-7

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(86)91016-8

journal_volume

135

pub_type

杂志文章

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