Decoding pressure stimulation locations on the fingers from human neural activation patterns.

Abstract:

:In this functional MRI study, we investigated how the human brain activity represents tactile location information evoked by pressure stimulation on fingers. Using the searchlight multivoxel pattern analysis, we looked for local activity patterns that could be decoded into one of four stimulated finger locations. The supramarginal gyrus (SMG) and the thalamus were found to contain distinct multivoxel patterns corresponding to individual stimulated locations. In contrast, the univariate general linear model analysis contrasting stimulation against resting phases for each finger identified activations mainly in the primary somatosensory cortex (S1), but not in SMG or in thalamus. Our results indicate that S1 might be involved in the detection of the presence of pressure stimuli, whereas the SMG and the thalamus might play a role in identifying which finger is stimulated. This finding may provide additional evidence for hierarchical information processing in the human somatosensory areas.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Kim J,Chung YG,Chung SC,Bülthoff HH,Kim SP

doi

10.1097/WNR.0000000000000683

subject

Has Abstract

pub_date

2016-11-09 00:00:00

pages

1232-6

issue

16

eissn

0959-4965

issn

1473-558X

journal_volume

27

pub_type

杂志文章
  • Changes in spinal cholecystokinin release after peripheral axotomy.

    abstract::The gene expression of cholecystokinin (CCK), a neuropeptide with anti-opioid properties, has been reported to be upregulated in some primary sensory neurons after a peripheral nerve lesion. We have recently demonstrated that the upregulation of CCK mRNA is not accompanied by an increased potassium-evoked release CCK-...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200101220-00018

    authors: Afrah AW,Gustafsson H,Olgart L,Brodin E,Stiller CO

    更新日期:2001-01-22 00:00:00

  • Caffeine elicits c-Fos expression in horizontal diagonal band cholinergic neurons.

    abstract::Caffeine is a widely self-administered psychostimulant with purported neuroprotective and procognitive effects in rodent models of aging. The cholinergic basal forebrain is important for arousal and attention and is implicated in age-related cognitive decline. Accordingly, we determined the effects of caffeine on chol...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283329c3a

    authors: Reznikov LR,Pasumarthi RK,Fadel JR

    更新日期:2009-12-09 00:00:00

  • Abnormal expression of ephrin-A5 affects brain development of congenital hypothyroidism rats.

    abstract::EphA5 and its ligand ephrin-A5 interaction can trigger synaptogenesis during early hippocampus development. We have previously reported that abnormal EphA5 expression can result in synaptogenesis disorder in congenital hypothyroidism (CH) rats. To better understand its precise molecular mechanism, we further analyzed ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001047

    authors: Suo G,Shen F,Sun B,Song H,Xu M,Wu Y

    更新日期:2018-08-01 00:00:00

  • Increased [125I]sulpiride binding in the subthalamic nucleus of rats with nigrostriatal lesions.

    abstract::Subthalamic nucleus (STN) hyperactivity follows lesions of mesencephalic dopaminergic neurons in animal models of Parkinson's disease. The mechanism leading to sustained STN hyperactivity in parkinsonism is not well understood, but it seems not to depend on the integrity of striato-pallido-subthalamic connections (the...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199905140-00020

    authors: Murer MG,Ferrario J,Delfino M,Dziewczapolski G,Gershanik OS,Raisman-Vozari R

    更新日期:1999-05-14 00:00:00

  • OFQ reverses the kappa-opioid receptor-mediated depression of calcium current in rat dorsal root ganglion neurons.

    abstract::Since the characterization of orphanin FQ (OFQ), the endogenous ligand of ORL1 receptor, much work has focused on its physiological functions. OFQ was reported to antagonize the effect of opioid-induced antinociception, although its mechanism remains obscure. In the present study, whole-cell patch clamp recording tech...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199806220-00034

    authors: Zhang M,Sun QL,Wan Y,Yao L,Yu YX,Han JS

    更新日期:1998-06-22 00:00:00

  • Increased severity of experimental colitis in alpha 5 nicotinic acetylcholine receptor subunit-deficient mice.

    abstract::Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200507130-00018

    authors: Orr-Urtreger A,Kedmi M,Rosner S,Karmeli F,Rachmilewitz D

    更新日期:2005-07-13 00:00:00

  • Secondary inhibition of 2-ketoglutarate dehydrogenase complex by MPTP.

    abstract::The parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridine (MPP+) acts through inhibition of complex I of the electron transport chain. Recent evidence suggests that it may also act through inhibition of 2-ketoglutarate dehydrogenase complex (KDHC). We confirmed this observation in isolated rat liver mitochondria ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199808240-00018

    authors: Joffe GT,Parks JK,Parker WD Jr

    更新日期:1998-08-24 00:00:00

  • Enhancement of electrically evoked startle-like responses by tetanic stimulation of the superior colliculus.

    abstract::Single-pulse unilateral electrical stimulation of either the amygdala or the inferior colliculus elicited startle-like responses in chloral hydrate anesthetized rats. EMG responses to intracranial stimulation were recorded from the anterior biceps femoris muscles. The EMG responses were generally enhanced following un...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200210070-00015

    authors: Lin C,Wan X,Zhao W,Ma C,Ma C,Gao Y,Zhou Y,Yeomans JS,Li L

    更新日期:2002-10-07 00:00:00

  • Cortical processing of musical consonance: an evoked potential study.

    abstract::Cortical processes underlying perception of musical consonance were investigated by long-latency auditory evoked potentials (EPs). Subjects listened to a random sequence of dyadic pure tones paired at various pitch intervals (1, 4, 6, 7, or 9 semitones). Amplitudes of P2 and N2 components of auditory EPs were signific...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200312190-00003

    authors: Itoh K,Suwazono S,Nakada T

    更新日期:2003-12-19 00:00:00

  • Amygdala depotentiation ex vivo requires mitogen-activated protein kinases and protein synthesis.

    abstract::We have recently characterized a form of ex vivo depotentiation (depotentiationex vivo), which correlates tightly with fear extinction, at thalamic input synapses onto the lateral amygdala. Here, we examined the effects of learning-attenuating drugs, reported to impair fear extinction when microinjected into the basol...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e328329412d

    authors: Kim J,Park S,Lee S,Choi S

    更新日期:2009-03-25 00:00:00

  • Stimulus inversion and the responses of face and object-sensitive cortical areas.

    abstract::Behavioral and neuropsychological studies suggest that upright and inverted face stimuli are processed by computationally and anatomically distinct systems. Specifically, inverted faces seem to be addressed by general object perception systems, avoiding face-specific processes. We tested this model by examining the fM...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00001756-199901180-00036

    authors: Aguirre GK,Singh R,D'Esposito M

    更新日期:1999-01-18 00:00:00

  • Electrophysiological dynamic brain connectivity during symbolic magnitude comparison in children with different mathematics achievement levels.

    abstract::Children with mathematical difficulties usually have an impaired ability to process symbolic representations. Functional MRI methods have suggested that early frontoparietal connectivity can predict mathematic achievements; however, the study of brain connectivity during numerical processing remains unexplored. With t...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000722

    authors: Gómez-Velázquez FR,Vélez-Pérez H,Espinoza-Valdez A,Romo-Vazquez R,Salido-Ruiz RA,Ruiz-Stovel V,Gallardo-Moreno GB,González-Garrido AA,Berumen G

    更新日期:2017-02-08 00:00:00

  • A simulated actuator driven by motor cortical signals.

    abstract::One problem in motor control concerns the mechanism whereby the central nervous system translates the motor cortical command encoded in cell activity into a coordinated contraction of limb muscles to generate a desired motor output. This problem is closely related to the design of adaptive systems that transform neuro...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199611040-00038

    authors: Lukashin AV,Amirikian BR,Georgopoulos AP

    更新日期:1996-11-04 00:00:00

  • Labelling of rat vagal preganglionic neurones by carbocyanine dye DiI applied to the heart.

    abstract::We describe a method for applying the carbocyanine dye DiI to the rat heart that takes advantage of the dye's lipophilic properties and its ability to diffuse easily into tissues, and results in specific retrograde labelling of cardiac vagal preganglionic neurones in the medulla oblongata. Most of the labelled neurone...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199904260-00004

    authors: Corbett EK,Batten TF,Kaye JC,Deuchars J,McWilliam PN

    更新日期:1999-04-26 00:00:00

  • GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures.

    abstract::The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200012180-00032

    authors: Bonde C,Kristensen BW,Blaabjerg M,Johansen TE,Zimmer J,Meyer M

    更新日期:2000-12-18 00:00:00

  • Neural substrates of tactile imagery: a functional MRI study.

    abstract::fMRI investigation on the neural substrates involved in tactile imagery is reported. Healthy subjects performed mental imagery of tactile stimulation on the dorsal aspect of the right hand. The results were compared with the regions of activation during the actual tactile stimulation. During imagery, contralateral pri...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200303240-00011

    authors: Yoo SS,Freeman DK,McCarthy JJ 3rd,Jolesz FA

    更新日期:2003-03-24 00:00:00

  • TGF beta 1 expression is initiated in adult auditory neurons by sectioning of the auditory nerve.

    abstract::Neuronotrophic factors (e.g. basic fibroblast growth factor, bFGF and nerve growth factor, NGF) have been demonstrated to respectively promote survival and neuritogenesis in cultures of dissociated adult rat spiral ganglia. Transforming growth factor beta (TGF beta 1) has been shown to modulate the response of culture...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199204000-00001

    authors: Lefebvre PP,Martin D,Staecker H,Weber T,Moonen G,Van de Water TR

    更新日期:1992-04-01 00:00:00

  • The intracellular fate of apolipoprotein E is tau dependent and apoe allele-specific.

    abstract::The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199604100-00010

    authors: Lovestone S,Anderton BH,Hartley C,Jensen TG,Jorgensen AL

    更新日期:1996-04-10 00:00:00

  • The function and expression of sproutin, a novel neurite outgrowth factor.

    abstract::TA20 cDNA was previously cloned as a neurite outgrowth factor from a hybridoma of mouse and rat cells, NG108-15. To clarify the detailed function and tissue distribution of this gene, homologous sequences of rat and mouse were identified. The cloned sequences had no homology with known genes, and was designated as spr...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199907130-00018

    authors: Tohda C,Jacobowitz DM

    更新日期:1999-07-13 00:00:00

  • Reduced programmed cell death in brains of serotonin transporter knockout mice.

    abstract::Serotonin (5-HT) is known to reduce apoptosis and in rodent models of brain ischemia. Modulation of programmed cell death during neural development was assessed in early postnatal brains of serotonin transporter (5-HTT) knockout mice, characterized by elevated extracellular 5-HT levels. The number of apoptotic cells v...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200303030-00009

    authors: Persico AM,Baldi A,Dell'Acqua ML,Moessner R,Murphy DL,Lesch KP,Keller F

    更新日期:2003-03-03 00:00:00

  • Resiliency of cortical neural networks against cascaded failures.

    abstract::Network tools have been extensively applied to study the properties of brain functional and anatomical networks. In this paper, resiliency of Caenorhabditis elegans cortical networks against cascaded failures is studied. To this end, directed network formed by chemical connections and undirected network formed by elec...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000421

    authors: Jalili M

    更新日期:2015-08-19 00:00:00

  • Successful outcomes of cochlear implantation in long-term unilateral deafness: brain plasticity?

    abstract::To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283642a93

    authors: Távora-Vieira D,Boisvert I,McMahon CM,Maric V,Rajan GP

    更新日期:2013-09-11 00:00:00

  • On the origin of Alzheimer's disease: a hypothesis.

    abstract::There is no unifying hypothesis to account for the anatomical distribution of neuropathology, the involvement of beta-amyloid precursor protein (beta APP) and the role of increasing age in triggering the Alzheimer disease process. We report here that layer II pre-alpha neurones in transentorhinal and entorhinal cortex...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199301000-00001

    authors: Roberts GW,Nash M,Ince PG,Royston MC,Gentleman SM

    更新日期:1993-01-01 00:00:00

  • Time of transforming growth factor beta 1 inoculation alters the incubation of BSE in mice.

    abstract::Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200410050-00018

    authors: Kempster S,Collins ME,Edington N

    更新日期:2004-10-05 00:00:00

  • The effects of patterned electrical stimulation combined with voluntary contraction on spinal reciprocal inhibition in healthy individuals.

    abstract::The aim of this study was to examine the effects of voluntary contraction (VC) on the modulation of reciprocal inhibition induced by patterned electrical stimulation (PES) in healthy individuals. Twelve healthy volunteers participated in this study. PES was applied to the common peroneal nerve with a train of 10 pulse...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000777

    authors: Takahashi Y,Fujiwara T,Yamaguchi T,Kawakami M,Mizuno K,Liu M

    更新日期:2017-05-24 00:00:00

  • NMDA-stimulated expression of BDNF mRNA in cultured cerebellar granule neurones.

    abstract::The brain-derived neurotrophic factor (BDNF) affects the developing cerebellar granule cells. Exposure of 9-11-day-old primary cultures of rat cerebellar granule neurones for 3 h to a more depolarizing medium (additional 15-30 mM KCl) stimulated the release of glutamate and increased the BDNF mRNAs levels. This BDNF a...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:

    authors: Favaron M,Manev RM,Rimland JM,Candeo P,Beccaro M,Manev H

    更新日期:1993-09-03 00:00:00

  • Hypoxia suppresses kainate-induced gamma-oscillations in rat hippocampal slices.

    abstract::Hypoxia or global ischemia causes rapid loss of consciousness and a sudden increase in spontaneous transmitter release suggesting that coordinated synaptic activity is impaired. Gamma oscillations (30-100 Hz) are thought to provide for binding of parallel processed information in the brain, contributing to cognition a...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3282f13e4f

    authors: Fano S,Behrens CJ,Heinemann U

    更新日期:2007-11-19 00:00:00

  • Phonetic invariance in the human auditory cortex.

    abstract::Neuromagnetic signals evoked by synthesized syllables (/bae/ and /gae/) were recorded over the left auditory cortex of healthy humans. The fundamental frequencies of the syllables varied as if the same speaker had pronounced them at 16 different pitches. Specific mismatch responses to infrequent syllables among freque...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199309150-00018

    authors: Aulanko R,Hari R,Lounasmaa OV,Näätänen R,Sams M

    更新日期:1993-09-30 00:00:00

  • Paraventricular nucleus injections of naloxone methiodide inhibit NPY's effects on energy substrate utilization.

    abstract::Microinjection of neuropeptide Y (NPY) into the paraventricular nucleus (PVN) of the hypothalamus stimulates eating and increases respiratory quotient. In contrast, administration of opioid receptor antagonists reduces food intake and suppresses NPY-induced feeding. The present study examined whether naloxone methiodi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200003200-00016

    authors: Currie PJ,Coscina DV,Moretti J,Avellino MD

    更新日期:2000-03-20 00:00:00

  • Thiamine deficiency alters APP but not presenilin-1 immunoreactivity in vulnerable brain regions.

    abstract::Presenilin-1 (PS-1) and amyloid precursor protein (APP) have been linked to the pathogenesis of Alzheimer's disease. While APP accumulation is well documented in several models of brain injury, the role of PS-1 levels in neurodegeneration, if any, remains to be elucidated. The current studies examined PS-1 and APP exp...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199707280-00041

    authors: Calingasan NY,Gandy SE,Gibson GE

    更新日期:1997-07-28 00:00:00