Abstract:
:The aim of this study was to examine the effects of voluntary contraction (VC) on the modulation of reciprocal inhibition induced by patterned electrical stimulation (PES) in healthy individuals. Twelve healthy volunteers participated in this study. PES was applied to the common peroneal nerve with a train of 10 pulses at 100 Hz every 2 s for 20 min. VC comprised repetitive ankle dorsiflexion at a frequency of 0.5 Hz for 20 min. All participants performed the following three tasks: (i) VC alone, (ii) PES alone, and (iii) PES combined with VC (PES+VC). Reciprocal inhibition was assessed using a soleus H-reflex conditioning-test paradigm at the time points of before, immediately after, 10 min after, 20 min after, and 30 min after the tasks. PES+VC increased the amount of reciprocal inhibition, with after-effects lasting up to 20 min. PES alone increased reciprocal inhibition and maintained the after-effects on reciprocal inhibition for 10 min, whereas VC alone increased only immediately after the task. VC could modulate the plastic changes in spinal reciprocal inhibition induced by PES in healthy individuals. PES combined with VC has a potential to modulate impaired reciprocal inhibition and it may facilitate functional recovery and improve locomotion after central nervous system lesions.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Takahashi Y,Fujiwara T,Yamaguchi T,Kawakami M,Mizuno K,Liu Mdoi
10.1097/WNR.0000000000000777subject
Has Abstractpub_date
2017-05-24 00:00:00pages
434-438issue
8eissn
0959-4965issn
1473-558Xjournal_volume
28pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::EphA5 and its ligand ephrin-A5 interaction can trigger synaptogenesis during early hippocampus development. We have previously reported that abnormal EphA5 expression can result in synaptogenesis disorder in congenital hypothyroidism (CH) rats. To better understand its precise molecular mechanism, we further analyzed ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001047
更新日期:2018-08-01 00:00:00
abstract::Matrix metalloproteinases (MMPs) may contribute to tissue damage after cerebral ischemia. In this study, wildtype and MMP-2 knockout mice were subjected to permanent and transient (2 h) occlusions of the middle cerebral artery. Gelatin zymography showed that MMP-9 levels were increased in all brains after ischemia. MM...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200109170-00050
更新日期:2001-09-17 00:00:00
abstract::GPR39, an orphan G protein-coupled receptor, has been recently identified as the receptor for the bioactive peptide obestatin. Obestatin is secreted from the stomach and acts as an anti-appetite hormone. This activity is induced whether obestatin is administered intraperitoneally or intracerebroventricularly. GPR39 is...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000215779.76602.93
更新日期:2006-05-29 00:00:00
abstract::Ciliary neurotrophic factor (CNTF), leukaemia inhibitory factor (LIF), oncostatin M (OSM), interleukin-6 (IL-6), and interleukin-11 (IL-11) are structurally and functionally related cytokines. We compared their survival-promoting activities on embryonic chick and newborn rat dorsal root ganglion (DRG) neurones. Human ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1995-12-29 00:00:00
abstract::Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson' disease motor imagery is impaired and that execution of overt movements is...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000132429.68206.48
更新日期:2004-06-28 00:00:00
abstract::The present study aimed to systematically observe the change of vanilloid receptor 1 (VR1) during inflammatory nociception induced by intraplantar injection of complete Freund's adjuvant (CFA) into the left hind paw in rats. Hot plate latency (HPL) was used to evaluate resulting thermal hyperalgesia and immunohistoche...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200403220-00016
更新日期:2004-03-22 00:00:00
abstract::Recent studies have discussed the role of the cerebellum in not only motor but also cognitive functions, and in particular, fronto-executive operations. Similar to a previous study on hemineglect patients, we recorded eye movements during a visual search task to investigate patients with isolated infarction of the cer...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000177015.75096.b6
更新日期:2005-09-08 00:00:00
abstract::Using in situ hybridization histochemistry and immunocytochemistry the induction of immediate early genes (IEGs) was studied in the rat superior cervical ganglion (SCG) after deafferentation, axotomy and sialectomy (removal of the submandibular gland). Control SCGs showed very low levels of IEGs, whereby Fos proteins ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199301000-00009
更新日期:1993-01-01 00:00:00
abstract::Neuromagnetic signals evoked by synthesized syllables (/bae/ and /gae/) were recorded over the left auditory cortex of healthy humans. The fundamental frequencies of the syllables varied as if the same speaker had pronounced them at 16 different pitches. Specific mismatch responses to infrequent syllables among freque...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199309150-00018
更新日期:1993-09-30 00:00:00
abstract::Although valproate (VPA) is used widely in the treatment of bipolar mood disorder and epilepsy, the precise mechanism of action in the brain remains elusive. In this study, we investigated the effects of subchronic VPA administrations on the expression of the cyclin-dependent kinase inhibitor (Cdkn) family in the hipp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000448
更新日期:2015-10-21 00:00:00
abstract::Activated NF-kappaB contributes to cerebral infarction by triggering a neuro-inflammatory response. Rats subjected to 90min middle cerebral artery occlusion developed a cortical infarct of 20+/-4% of hemispheric volume (n = 8). Treatment with the proteasome inhibitor CVT-634 resulted in a significantly smaller infarct...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200002070-00041
更新日期:2000-02-07 00:00:00
abstract::We report two functional magnetic resonance imaging experiments which reveal similarities and differences between perceptual and imaginal networks within the single visual submodality of colour. The first experiment contrasted viewing of a coloured and grey-scale Mondrian display, while the second contrasted a relativ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199804200-00012
更新日期:1998-04-20 00:00:00
abstract::Ascorbate and glutathione (GSH) are the primary water-soluble antioxidants in the CNS. Oxidative stress, sometimes indicated by loss of these antioxidants, has been linked to several clinical and experimental conditions, including cerebral ischemia. These conditions are also gender-linked, with greater incidence or se...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199507310-00005
更新日期:1995-07-31 00:00:00
abstract::We analysed the effects of morphine microinjections (0.2 microliter) into the subnucleus oralis (SNO), i.e. the rostral division of the spinal trigeminal nucleus, on the formalin test adapted for orofacial pain. Duration of rubbing following an injection (50 microliters) of formalin solution (1.5%) in the right upper ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199501000-00034
更新日期:1995-01-26 00:00:00
abstract::NMDA receptors (NR) are important in many neurological processes. Using a large series of human brain tissue, we show that the distribution of NR2A/B immunoreactivity varies according to position along a gyrus. For pyramidal neurons in laminae II and III, immunoreactivity is most marked at gyral crown and gyral lips, ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200008030-00050
更新日期:2000-08-03 00:00:00
abstract::DJ-1, originally identified as an oncogene product, is involved in multiple processes, including cellular transformation, the oxidative stress response, and transcriptional regulation. We had previously found that DJ-1 was closely associated with the proliferation and differentiation of cultured neuronal stem cells. I...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000956
更新日期:2018-03-07 00:00:00
abstract::We examined the electrophysiological correlates of the processing of social exclusion and inclusion by using a modified version of the Cyberball paradigm. Exclusion was found to be associated with a significant increase in the P3 complex. The frontal-central P3a was primarily related to the affective processing of rej...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283476b67
更新日期:2011-06-22 00:00:00
abstract::In several central nervous system neuronal populations, axotomy triggers the upregulation of regeneration-associated genes such as c-Jun, which determines neurons ability to regenerate axon in a growth-permissive environment. We analyzed the expression of c-Jun in rat ventral medullary neurons after cervical hemisecti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000179075.32035.0f
更新日期:2005-09-28 00:00:00
abstract::Homotopic and isochronic transplantation of the alar plate of the rhombomeres 7 and 8 was performed between chick and quail embryos at the stage of 10-14 somites. Analysis of the graft derivatives in 12-day-old chimeric embryos by means of the quail nucleolar marker showed that the ipsilateral inferior olive is formed...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199605170-00013
更新日期:1996-05-17 00:00:00
abstract::Hypoxic-ischemic represents a common cause of damage to the prenatal brain and can co-occur with prematurity. Prematurity is associated with emergent language impairments, and it has been suggested that rapid auditory processing deficits play a causal role in language difficulties. We previously demonstrated rapid aud...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175613.16183.6c
更新日期:2005-08-22 00:00:00
abstract::It has been suggested that high levels of prenatal testosterone exposure are implied in the aetiology of dyslexia and its frequently co-occurring sensory problems. This study examined 2D : 4D digit ratio (a marker of fetal testosterone exposure) in dyslexic and normal reading children. No group differences in 2D : 4D ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282e9a754
更新日期:2007-09-17 00:00:00
abstract::Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium. Repeated song presentations caused lower expression of th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833730b7
更新日期:2010-04-21 00:00:00
abstract::Sensory information from the genitourinary tract is transmitted to perineal muscle reflex circuits in the spinal cord and to the medullary reticular formation (MRF). This is the first report of a functional descending connection between neurons in the MRF and sensory inputs of the pudendal motoneuron reflex circuitry....
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199801260-00030
更新日期:1998-01-26 00:00:00
abstract::Transplantation of olfactory ensheathing cells (OECs) into photochemically damaged rat spinal cord diminished astrocyte reactivity and parenchyma cavitation. The photochemical lesion performed at T12--L1 resulted in severe damage to the spinal cord, so that during the first 15 days postoperation all rats dragged their...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200108080-00005
更新日期:2001-08-08 00:00:00
abstract::We screened proteins for interaction with presenilin (PS) 1, and cloned the full-length cDNA of human delta-catenin, which encoded 1225 amino acids. Yeast two-hybrid assay, GST binding assay and immunoprecipitation demonstrated that delta-catenin interacted with a hydrophilic loop region in the endoproteolytic C-termi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199902250-00022
更新日期:1999-02-25 00:00:00
abstract::Compartmental models of thalamic reticular (RE) neurons were investigated based on current-clamp and voltage-clamp data. Spontaneous oscillations in the model arise from the interaction between inhibitory synaptic currents and the rebound burst of RE cells. These oscillations critically depend on the level of the rest...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199411000-00003
更新日期:1994-11-21 00:00:00
abstract::We report an event-related potential study investigating the neural basis of interference and facilitation in the picture-word interference paradigm with immediate overt naming. We used the high temporal resolution of the electrophysiological response to dissociate general and specific interference processes, by compa...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/WNR.0b013e328309ecd1
更新日期:2008-08-06 00:00:00
abstract::Heptylene-linked bis-(9-amino-1,2,3,4-tetrahydroacridine) (bis(7)-tacrine) is a potential palliative therapeutic agent for Alzheimer's disease (AD), on the basis of its superior acetylcholinesterase (AChE) inhibition and memory-enhancing potency relative to tacrine. In this study we report that bis(7)-tacrine exhibits...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199903170-00024
更新日期:1999-03-17 00:00:00
abstract::Adeno-associated virus type2 (AAV-2) binds to heparan-sulfate proteoglycans on the cell surface. In vivo, attachment of viral particles to cells adjacent to the injection tract limits the distribution of AAV-2 when infused into the CNS parenchyma and heparin co-infusion might decrease the binding of AAV-2 particles to...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200107030-00037
更新日期:2001-07-03 00:00:00
abstract::Pharmacological activation of group III metabotropic glutamate receptors (mGluR) or inhibition of group I mGluR by subtype-selective ligands is neuroprotective in experimental models of Parkinson's disease. The aim of this study was to investigate whether targeting both receptor subtypes simultaneously produces enhanc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f602df
更新日期:2008-03-05 00:00:00