Abstract:
:Codons play important roles in regulating gene expression levels and mRNA half-lives. However, codon usage and related studies in multicellular organisms still lag far behind those in unicellular organisms. In this study, we describe for the first time genome-wide patterns of codon bias in Morus notabilis (mulberry tree), and analyze genome-wide codon usage in 12 other species within the order Rosales. The codon usage of M. notabilis was affected by nucleotide composition, mutation pressure, nature selection, and gene expression level. Translational selection optimal codons were identified and highly expressed genes of M. notabilis tended to use the optimal codons. Genes with higher expression levels have shorter coding region and lower amino acid complexity. Housekeeping genes showed stronger translational selection, which, notably, was not caused by the large differences between the expression level of housekeeping genes and other genes.
journal_name
Genomejournal_title
Genomeauthors
Wen Y,Zou Z,Li H,Xiang Z,He Ndoi
10.1139/gen-2016-0129subject
Has Abstractpub_date
2017-06-01 00:00:00pages
473-484issue
6eissn
0831-2796issn
1480-3321journal_volume
60pub_type
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