解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Combinatorial spatial and temporal patterning of stem cells is a powerful mechanism for the generation of neural diversity in insect and vertebrate nervous systems. In the developing Drosophila medulla, the neural stem cells of the outer proliferation center (OPC) are spatially patterned by the mutually exclusive expr...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0034
更新日期:2021-02-01 00:00:00
abstract::Allopolyploids undergo 'genomic shock' leading to large genetic and epigenetic modifications. Previous studies mainly focused on nuclear changes, while little is known about the inheritance and changes of organelle genome in allopolyploidization. The synthetic allotetraploid Cucumis ×hytivus, which is generated via hy...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0134
更新日期:2021-01-18 00:00:00
abstract::Asarum sieboldii a well-known traditional Chinese medicinal herb, is used for curing inflammation and ache. It contains both bioactive ingredient asarinin and the toxic compound aristolochic acid. To address further breeding demand, genes involved in the biosynthetic pathways of asarinin and aristolochic acid should b...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0095
更新日期:2020-12-15 00:00:00
abstract::Canonical histones (H2A, H2B, H3, and H4) are present in all eukaryotes where they package genomic DNA and participate in numerous cellular processes, such as transcription regulation and DNA repair. In addition to the canonical histones, there are many histone variants, which have different amino acid sequences, poss...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0094
更新日期:2020-11-27 00:00:00
abstract::Genomics is both data and compute intensive discipline. The success of genomics depends on adequate informatics infrastructure that can address growing data demands and enable a diverse range of resource-intensive computational activities. Designing a suitable Infrastructure is a challenging task, and its success larg...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0096
更新日期:2020-11-20 00:00:00
abstract::Despite being a controversial crop, Cannabis sativa L. has a long history of cultivation throughout the world. Following recent legalisation in Canada, it is emerging as an important plant for both medicinal and recreational purposes. Recent progress in genome sequencing of both cannabis and hemp varieties allows for ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0087
更新日期:2020-11-13 00:00:00
abstract::Globally, biodiversity is declining as a result of anthropogenic pressures, and this could lead to extinction of some species before they are discovered. The loss of insect taxa is of prime concern, given recent reports of significant declines in the populations of many taxa across the globe. Efforts to document biodi...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0193
更新日期:2020-11-10 00:00:00
abstract::Sequence-based markers have added a new dimension in the efficiency of identifying alien introgressions in wheat. Expressed sequence tag-sequence tagged sites (EST-STS) markers have proved useful in tracing alien chromatin. In this study, we report the development of Thinopyrum bessarabicum- and Secale anatolicum-spec...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0057
更新日期:2020-11-01 00:00:00
abstract::Genotyping-by-sequencing (GBS) is a rapid, flexible, low-cost, and robust genotyping method that simultaneously discovers variants and calls genotypes within a broad range of samples. These characteristics make GBS an excellent tool for many applications and research questions from conservation biology to functional g...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0077
更新日期:2020-11-01 00:00:00
abstract::Natural selection and domestication have shaped modern horse populations, resulting in a vast range of phenotypically diverse breeds. Horse breeds are classified into three types (pony, light, and draft) generally based on their body type. Understanding the genetic basis of horse type variation and selective pressures...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2020-0001
更新日期:2020-08-01 00:00:00
abstract::Brucella spp., facultative intracellular pathogens that can persistently colonize animal host cells and cause zoonosis, affect public health and safety. A Brucella strain was isolated from yak in Qinghai Province. To detect whether this isolate could cause an outbreak of brucellosis and to reveal its genetic character...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0101
更新日期:2020-08-01 00:00:00
abstract::Nematodes are frequently cited as underrepresented in faunistic surveys using DNA barcoding with COI. This underrepresentation is generally attributed to a limited presence of nematodes in DNA databases which, in turn, is often ascribed to structural variability and high evolutionary rates in nematode mitochondrial ge...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0196
更新日期:2020-06-11 00:00:00
abstract::The Himalayan marmot (Marmota himalayana), a natural host and transmitter of plague, is also susceptible to the hepadnavirus infection. To reveal the genetic basis of the hepadnavirus susceptibility and the immune response to plague, we systematically characterized the features of immune genes in Himalayan marmot with...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0161
更新日期:2020-06-01 00:00:00
abstract::Unequal utilization of synonymous codons is a well-known phenomenon among living organisms. This phenomenon plays a major role in the enhancement of the accuracy and efficiency of translation. Gymnosperms are rarely paid attention in this aspect. Understanding the degree of and determining the forces influencing codon...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0165
更新日期:2020-04-01 00:00:00
abstract::Lasiodiplodia theobromae (Pat.) Griffon & Maubl., a member of the family Botryosphaeriaceae, is becoming a significant threat to crops and woody plants in many parts of the world, including the major cacao growing areas. While attempting to isolate Ceratobasidium theobromae, a causal agent of vascular streak dieback (...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0112
更新日期:2020-01-01 00:00:00
abstract::Owing to its high nutritive, economic, and medicinal values, Akebia trifoliata has received increased attention, making worthy of being used as a new fruit crop for further domestication and commercialization in China. However, molecular research of A. trifoliata has lagged as investigations of its genomic resources a...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0068
更新日期:2019-12-01 00:00:00
abstract::Unisexual Ambystoma are the oldest known unisexual vertebrates and comprise a lineage of eastern North American all female salamanders that reproduce by stealing sperm from as many as five normally bisexual congeneric species. The sperm may be used to only stimulate egg development by gynogenesis but can be incorporat...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2019-0034
更新日期:2019-08-01 00:00:00
abstract::European hazelnut (Corylus avellana L.) is a strictly cross-pollinated diploid tree species, which has its northernmost populations in Fennoscandia, and it was one of the first species to recolonize northern Europe after the last ice age. Hazelnut produces edible nuts in Finland but nowadays they are underutilized as ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0193
更新日期:2019-08-01 00:00:00
abstract::Being an essential mineral nutrient, potassium (K+) plays numerous important roles in plant growth and development and determines the yield and quality of crop products. The cellular level of K+ is controlled to a large extent by the K+ transporter, which belongs to the KT/HAK/KUP (HAK) family. However, little is know...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0187
更新日期:2019-04-01 00:00:00
abstract::Bacteria are essential components of natural environments. They contribute to ecosystem functioning through roles as mutualists and pathogens for larger species, and as key components of food webs and nutrient cycles. Bacterial communities respond to environmental disturbances, and the tracking of these communities ac...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0064
更新日期:2019-03-01 00:00:00
abstract::Expensive and unsustainable fishmeal is increasingly being replaced with cheaper lipids and carbohydrates as sources of energy in aquaculture. Although it is known that the excess of lipids and carbohydrates has negative effects on nutrient utilization, growth, metabolic homeostasis, and health of fish, our current un...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0159
更新日期:2019-02-01 00:00:00
abstract::Large sequence insertion (LSI) is one of the structural variations (SVs) that may cause phenotypic differences in plants. To identify the LSIs using medium-coverage sequencing data of four wild soybean (Glycine soja) genotypes, we designed a hybrid approach combining de novo assembly and read mapping. Total reads and ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0027
更新日期:2018-10-01 00:00:00
abstract::Paenibacillus terrae NK3-4 is a plant growth-promoting rhizobacterium that may be useful for controlling plant diseases. We conducted a genomic analysis and identified the genes mediating antimicrobial functions. Additionally, an extracellular antifungal protein component was isolated and identified. The draft genome ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0113
更新日期:2018-10-01 00:00:00
abstract::Brachypodium distachyon (n = 5) is a diploid and has been widely used as a genetic model. Brachypodium stacei (n = 10) and B. hybridum (n = 15) are species that are related to B. distachyon, leading to an hypothesis that they are part of a polyploid series based on x = 5. Several lines of evidence suggest that this hy...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0013
更新日期:2018-08-01 00:00:00
abstract::Compared to traditional morphological identification, DNA barcoding-molecular identification based on sequencing of a segment of mitochondrial cytochrome c oxidase subunit I (COI)-provides a shortcut to authenticating chelonian identifications. Here, we selected 63 government-seized chelonian specimens deposited at Ta...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0264
更新日期:2018-08-01 00:00:00
abstract::Post-glacial origins of woodland caribou (Rangifer tarandus subsp.) on the island of Newfoundland and their relationship to mainland populations have been uncertain. Sequence analysis of 2223 bp of the mitochondrial DNA control region and cytochrome b gene from 233 Newfoundland caribou identified 32 haplotypes in four...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0199
更新日期:2018-08-01 00:00:00
abstract::The combination of two divergent genomes during hybridization can result in "genome shock". Although genome shock has been reported in the hybrids of some herbaceous plants, the pattern and the principle it follows are far from understood, especially in woody plants. Here, the gene expression patterns were remodeled i...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0105
更新日期:2018-07-01 00:00:00
abstract::Karyotypes of three accessions of Hordeum chilense (H1, H16, and H7), Hordeum vulgare, and Triticum aestivum were characterized by physical mapping of several repetitive sequences. A total of 14 repetitive sequences were used as probes for fluorescence in situ hybridization (FISH) with the aim of identifying inter- an...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2018-0016
更新日期:2018-06-01 00:00:00
abstract::Lobster mushroom is a wild edible mushroom with potential commercial value. It is the product resulting of the infection, most commonly of Russula brevipes, by Hypomyces lactifluorum. This study undertook quantitative polymerase chain reaction analysis of tissues sampled at different infection stages to investigate R....
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0168
更新日期:2018-05-01 00:00:00
abstract::The genetic control of adult plant resistance to Stagonospora nodorum blotch (SNB) is complex, consisting of genes with minor effects interacting in an additive manner. Earlier studies detected quantitative trait loci (QTL) for flag leaf resistance in successive years on chromosomes 1B, 2A, 2D, and 5B using SSR- and D...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0203
更新日期:2018-02-01 00:00:00
abstract::Knowledge of the locations of repeat elements could be very important in the assembly of genome sequences and their assignment to physical chromosomes. Genomic and species relationships among 16 species were investigated using fluorescence in situ hybridization (FISH) with the Am1 and (ACT)6 probes. The Am1 oligonucle...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0132
更新日期:2018-01-01 00:00:00
abstract::RNA-Seq methodology has been used to generate a comprehensive transcriptome sequence resource for perennial ryegrass, an important temperate pasture grass species. A total of 931 547 255 reads were obtained from libraries corresponding to 19 distinct tissue samples, including both vegetative and reproductive stages of...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2017-0077
更新日期:2017-12-01 00:00:00
abstract::The emergence of next generation sequencing has increased by several orders of magnitude the amount of data available for phylogenetics. Reduced representation approaches, such as restriction-sited associated DNA sequencing (RADseq), have proven useful for phylogenetic studies of non-model species at a wide range of p...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2016-0202
更新日期:2017-09-01 00:00:00
abstract::Eucalyptus globulus subsp. globulus Labill. (Tasmanian Blue Gum), native to southeast Australia, is a benchmark species for the pulp and paper industry. We genotyped 397 trees from 16 populations of E. globulus representing the native diversity in Australia using 24 microsatellite loci. Eight genetically distinct grou...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2016-0218
更新日期:2017-09-01 00:00:00
abstract::Aegilops is a genus belonging to the family Poaceace, which have played an indispensible role in the evolution of bread wheat and continues to do so by transferring genes by wide hybridization. Being the secondary gene pool of wheat, gene transfer from Aegilops poses difficulties and segregation distortion is common. ...
journal_title:Genome
pub_type: 杂志文章,评审
doi:10.1139/gen-2017-0023
更新日期:2017-08-01 00:00:00
abstract::Orchidaceae, one of the largest families of angiosperms, is represented in India by 1600 species distributed in diverse habitats. Orchids are in high demand owing to their beautiful flowers and therapeutic properties. Overexploitation and habitat destruction have made many orchid species endangered. In the absence of ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2016-0215
更新日期:2017-08-01 00:00:00
abstract::Brachypodium distachyon has been proposed as a model plant for agriculturally important cereal crops such as wheat and barley. Seed coat colour change from brown-red to yellow was observed in a mutant line (142-3) of B. distachyon, which was induced by chronic gamma radiation. In addition, dwarf phenotypes were observ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2016-0145
更新日期:2017-07-01 00:00:00
abstract::Codons play important roles in regulating gene expression levels and mRNA half-lives. However, codon usage and related studies in multicellular organisms still lag far behind those in unicellular organisms. In this study, we describe for the first time genome-wide patterns of codon bias in Morus notabilis (mulberry tr...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2016-0129
更新日期:2017-06-01 00:00:00
abstract::Leymus mollis (Trin.) Pilg. (2n = 4x = 28, NsNsXmXm) possesses a number of valuable genes against biotic and abiotic stress, which could be transferred into common wheat background for wheat improvement. In the present study, we determined the karyotypic constitution of a wheat - L. mollis double disomic addition line...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2016-0151
更新日期:2017-05-01 00:00:00
abstract::Yams are species of the genus Dioscorea (family Dioscoreaceae), which consists of approximately 630 species. The majority of the world production of yams occurs in Africa with 58.8 million t annually, but they are also produced in the Americas and Asia. The saponins in yams have been reported to possess various proper...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/gen-2015-0105
更新日期:2017-03-01 00:00:00