A study of homologous chromosomes using a morphometric approach.

Abstract:

:A previous study of 100 karyotyped metaphase cells has demonstrated the utility of a graphic arts tool in deriving chromosome measurements for relative length determination. In the present study we utilize this same approach to address the question: "What are the average differences in relative lengths between apparently normal homologous chromosomes?" Normal standards derived from this study will be useful for testing specific hypotheses involving heteromorphic differences between homologs. No such data on normal controls could readily be found in either An International System for Human Cytogenetic Nomenclature (1985) or elsewhere.

journal_name

Genome

journal_title

Genome

authors

Mark HF,Wyandt HE,Pan T,Mark R Jr,Paramenter M,Campbell W,Mark Y

doi

10.1139/g93-132

subject

Has Abstract

pub_date

1993-10-01 00:00:00

pages

1003-6

issue

5

eissn

0831-2796

issn

1480-3321

journal_volume

36

pub_type

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