SU-E-T-302: A Simulation Study with Geant4 Investigating the Secondary Prompt Gamma Emissions from Incident 40 MeV Protons Onto Various Materials.

Abstract:

PURPOSE:This study aims to investigate the prompt secondary gamma spectrum and thedepth-dose distributions of incident 40 MeV protons onto various phantom materials.The goal is to find a relationship between the secondary prompt gamma emissions andthe range of the incident particles. METHODS:An application was constructed using the Geant4 Monte CarloToolkit utilizing various physics packages. Several phantom materials were irradiatedwith a pencil beam of 40 MeV protons. These materials include PMMA (C5H8O2,density 1.18 g/cm3 ) and the built-in Geant4 materials bone, soft-tissue, and water. Foreach simulation, the energy deposited from the incident proton was recorded every 1 mmincrement of depth in the phantom. The resulting prompt secondary gamma emissionswere recorded from 0 to 10 MeV in energy bins of 10 keV. RESULTS:The secondary prompt gamma spectrum has various peaks. The peaks locatedabout 4.4 and 6 MeV correspond to the carbon and oxygen de-excitation photons,respectively. Our simulations show greater production of the higher-energy gammaparticles closer to the Bragg-Peak. When we plot the oxygen peak against the normalizedBragg-Peak we found that in all materials the difference between Bragg-Peak and theoxygen de-excitation photon peak to be about 2 mm. The oxygen peak could be used inthe clinic for range verification of the incident proton beam. CONCLUSIONS:Our Geant4 Monte Carlo application was used to investigate the secondaryprompt gamma emissions from incident 40 MeV protons. A relationship was betweenthe 6 MeV peak and the incident proton Bragg Peak. We believe that prominent peaksaround 4 and 6 MeV can be used to locate the range of the incident beam provided adetector system is built that can count these high-energy gamma particles.

journal_name

Med Phys

journal_title

Medical physics

authors

Lau A,Chen Y,Ahmad S

doi

10.1118/1.4735388

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

3773

issue

6Part14

eissn

0094-2405

issn

2473-4209

journal_volume

39

pub_type

杂志文章
  • Use of a constrained hierarchical optimization dataset enhances knowledge-based planning as a quality assurance tool for prostate bed irradiation.

    abstract:PURPOSE:To investigate whether building a knowledge-based planning (KBP) model with prostate bed plans constructed from constrained hierarchical optimization (CHO) would result in more efficient model construction with more consistent output than a model built using plans from a traditional, trial-and-error-based optim...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13163

    authors: Lin YH,Hong LX,Hunt MA,Berry SL

    更新日期:2018-10-01 00:00:00

  • Contrast enhancement of portal images by selective histogram equalization.

    abstract::Because of the high energy of the treatment beam, contrast of portal verification films is very poor. A simple contrast enhancement technique is described which we have labeled selective histogram equalization (SHE), to improve visualization of double-exposure portal images and this facilitate the beam verification pr...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597085

    authors: Crooks I,Fallone BG

    更新日期:1993-01-01 00:00:00

  • Image resolution of a microchannel plate x-ray image intensifier.

    abstract::The resolution has been evaluated for an experimental x-ray image intensifier employing three microchannel plates (MCPs) as the photon absorber and electron multipliers. The line spread function (LSF) was measured and used for determination of the modulation transfer function (MTF). The MTF was found to be independent...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594463

    authors: Gould RG

    更新日期:1978-01-01 00:00:00

  • Examination of a deformable motion model for respiratory movements and 4D dose calculations using different driving surrogates.

    abstract:PURPOSE:The aim of this study was to evaluate a surrogate-driven motion model based on four-dimensional computed tomography that is able to predict CT volumes corresponding to arbitrary respiratory phases. Furthermore, the comparison of three different driving surrogates is examined and the feasibility of using the mod...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12243

    authors: Wölfelschneider J,Seregni M,Fassi A,Ziegler M,Baroni G,Fietkau R,Riboldi M,Bert C

    更新日期:2017-06-01 00:00:00

  • Off-axis beam quality change in linear accelerator x-ray beams.

    abstract::The effective energy of the x-ray beam from linear accelerators changes as a function of the position in the beam due to nonuniform filtration by the flattening filter. In this work, the transmittance through a water column was measured in good geometry and the beam quality characterized in units of HVL in water. Meas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594677

    authors: Hanson WF,Berkley LW,Peterson M

    更新日期:1980-03-01 00:00:00

  • Verification of radiotherapy treatments: computerized analysis of the size and shape of radiation fields.

    abstract::An automated technique has been developed for the verification of treatment field size and shape in external beam radiation therapy. Portal images from film or digital on-line imaging system are analyzed, and basic parameters are derived to describe the field size and shape from the contour points on the field boundar...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597017

    authors: Leszczynski KW,Shalev S,Gluhchev G

    更新日期:1993-05-01 00:00:00

  • Image noise and dose performance across a clinical population: Patient size adaptation as a metric of CT performance.

    abstract:PURPOSE:Modern CT systems adjust X-ray flux accommodating for patient size to achieve certain image noise values. The effectiveness of this adaptation is an important aspect of CT performance and should ideally be characterized in the context of real patient cases. The objective of this study was to characterize CT per...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12172

    authors: Ria F,Wilson JM,Zhang Y,Samei E

    更新日期:2017-06-01 00:00:00

  • Thermoacoustic molecular tomography with magnetic nanoparticle contrast agents for targeted tumor detection.

    abstract:PURPOSE:The primary feasibility steps of demonstrating the ability of microwave-induced thermoacoustic (TA) in phantoms have been previously reported. However, none were shown to target a diseased site in living subjects in thermoacoustic tomography (TAT) field so far. To determine the expressions of oncogenic surface ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3466696

    authors: Nie L,Ou Z,Yang S,Xing D

    更新日期:2010-08-01 00:00:00

  • Small-field electron dosimetry for the Philips SL25 linear accelerator.

    abstract::Electron-beam characteristics of a Philips SL25 linear accelerator have been studied. Central-axis percentage depth doses, cross-beam profiles and beam output factors of 6-, 10-, and 20-MeV beams, selected from the available energy range of 4 to 22 MeV, are reported in this paper. The main thrust of this work is to de...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596471

    authors: Rashid H,Islam MK,Gaballa H,Rosenow UF,Ting JY

    更新日期:1990-07-01 00:00:00

  • Sci-Fri AM: Imaging - 04: SPECT-based functional lung imaging in the prediction of radiation pneumonitis: A retrospective clinical and dosimetric correlation.

    abstract:PURPOSE:To investigate whether functionally-weighted dose-volume histogram (DVH) parameters are more predictive of radiation-induced pneumonitis (RP) than standard parameters such as V20 and mean lung dose (MLD). MATERIALS AND METHODS:A retrospective chart review identified 26 patients who received curative-intent rad...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4740190

    authors: Hoover D,Reid RH,Rodrigues G,Wong E,Stitt L,Yaremko BP

    更新日期:2012-07-01 00:00:00

  • Subvoxel precise skeletons of volumetric data based on fast marching methods.

    abstract::The accurate calculation of the skeleton of an object is a problem not satisfactorily solved by existing approaches. Most algorithms require a significant amount of user interaction and use a voxel grid to compute discrete and often coarse approximations of this representation of the data. We present a novel, automati...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2409238

    authors: Van Uitert R,Bitter I

    更新日期:2007-02-01 00:00:00

  • Novel detector design for reducing intercell x-ray cross-talk in the variable resolution x-ray CT scanner: a Monte Carlo study.

    abstract:PURPOSE:The variable resolution x-ray (VRX) CT scanner provides substantial improvement in the spatial resolution by matching the scanner's field of view (FOV) to the size of the object being imaged. Intercell x-ray cross-talk is one of the most important factors limiting the spatial resolution of the VRX detector. In ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3555035

    authors: Arabi H,Asl AR,Ay MR,Zaidi H

    更新日期:2011-03-01 00:00:00

  • Motion estimation for cardiac functional analysis using two x-ray computed tomography scans.

    abstract:PURPOSE:This work concerns computed tomography (CT)-based cardiac functional analysis (CFA) with a reduced radiation dose. As CT-CFA requires images over the entire heartbeat, the scans are often performed at 10-20% of the tube current settings that are typically used for coronary CT angiography. A large image noise th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12425

    authors: Fung GSK,Ciuffo L,Ashikaga H,Taguchi K

    更新日期:2017-09-01 00:00:00

  • Feasibility of estimating regional mechanical properties of cerebral aneurysms in vivo.

    abstract:PURPOSE:In this article, the authors studied the feasibility of estimating regional mechanical properties in cerebral aneurysms, integrating information extracted from imaging and physiological data with generic computational models of the arterial wall behavior. METHODS:A data assimilation framework was developed to ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3355933

    authors: Balocco S,Camara O,Vivas E,Sola T,Guimaraens L,Gratama van Andel HA,Majoie CB,Pozo JM,Bijnens BH,Frangi AF

    更新日期:2010-04-01 00:00:00

  • Correcting magnetic resonance k-space data for in-plane motion using an optical position tracking system.

    abstract:PURPOSE:Motion is a major confound of image quality in MRI. A method of retrospectively correcting the effects of rotations and translations on the acquired k-space data is presented. METHODS:In two phantom experiments of well-controlled translation and rotation, two MRI-compatible infrared cameras recorded motion dat...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3254189

    authors: Marxen M,Marmurek J,Baker N,Graham SJ

    更新日期:2009-12-01 00:00:00

  • On the speckle-free nature of photoacoustic tomography.

    abstract:PURPOSE:A long-standing conundrum is why photoacoustic tomography (PAT) possesses the unique ability to produce images devoid of speckle artifacts while all other coherent imaging technologies do not. METHODS:In this paper, we explain the inherent mechanism that suppresses speckle in PAT, and the analysis was validate...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3187231

    authors: Guo Z,Li L,Wang LV

    更新日期:2009-09-01 00:00:00

  • Tomotherapy dose distribution verification using MAGIC-f polymer gel dosimetry.

    abstract:PURPOSE:This paper presents the application of MAGIC-f gel in a three-dimensional dose distribution measurement and its ability to accurately measure the dose distribution from a tomotherapy unit. METHODS:A prostate intensity-modulated radiation therapy (IMRT) irradiation was simulated in the gel phantom and the treat...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4704496

    authors: Pavoni JF,Pike TL,Snow J,DeWerd L,Baffa O

    更新日期:2012-05-01 00:00:00

  • SU-E-T-145: MRI Gel Dosimetry Applied to Dose Profile Determination for 50kV X-Ray Tube.

    abstract:PURPOSE:The aim of this study was to use MRI gel dosimetry to determine the dose profile of 50kV MAGNUM® X-ray tube, MOXTEK Inc., in order to calibrate small solid dosimeters of alanine, tooth enamel and LiF-TLDs, commonly used in clinical quality assurance and datation dosimetry. METHODS:MAGIC-f polymer gel was kept ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735203

    authors: Schwarcke M,Marques T,Nicolucci P,Filho OB

    更新日期:2012-06-01 00:00:00

  • Completeness map evaluation demonstrated with candidate next-generation cardiac CT architectures.

    abstract:PURPOSE:In this report, the authors introduce the general concept of the completeness map, as a means to evaluate the completeness of data acquired by a given CT system design (architecture and scan mode). They illustrate the utility of completeness map by applying the completeness map concept to a number of candidate ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3700172

    authors: Liu B,Bennett J,Wang G,De Man B,Zeng K,Yin Z,Fitzgerald P,Yu H

    更新日期:2012-05-01 00:00:00

  • Beam modeling and verification of a photon beam multisource model.

    abstract::Dose calculations for treatment planning of photon beam radiotherapy require a model of the beam to drive the dose calculation models. The beam shaping process involves scattering and filtering that yield radiation components which vary with collimator settings. The necessity to model these components has motivated th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1898485

    authors: Ahnesjö A,Weber L,Murman A,Saxner M,Thorslund I,Traneus E

    更新日期:2005-06-01 00:00:00

  • Tree structured wavelet transform segmentation of microcalcifications in digital mammography.

    abstract::A novel multistage algorithm is proposed for the automatic segmentation of microcalcification clusters (MCCs) in digital mammography. First, a previously reported tree structured nonlinear filter is proposed for suppressing image noise, while preserving image details, to potentially reduce the false positive (FP) dete...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597562

    authors: Qian W,Kallergi M,Clarke LP,Li HD,Venugopal P,Song D,Clark RA

    更新日期:1995-08-01 00:00:00

  • A correction-based dose calculation algorithm for kilovoltage x rays.

    abstract::Frequent and repeated imaging procedures such as those performed in image-guided radiotherapy (IGRT) programs may add significant dose to radiosensitive organs of radiotherapy patients. It has been shown that kV-CBCT results in doses to bone that are up to a factor of 3-4 higher than those in surrounding soft tissue. ...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.3014197

    authors: Ding GX,Pawlowski JM,Coffey CW

    更新日期:2008-12-01 00:00:00

  • Classification of breast lesions using segmented quantitative ultrasound maps of homodyned K distribution parameters.

    abstract:PURPOSE:Statistical modeling of an ultrasound backscattered echo envelope is used for tissue characterization. However, in the presence of complex structures within the analyzed area, estimation of parameters is disturbed and unreliable, e.g., in the case of breast tumor classification. In order to improve the differen...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4962928

    authors: Byra M,Nowicki A,Wróblewska-Piotrzkowska H,Dobruch-Sobczak K

    更新日期:2016-10-01 00:00:00

  • Characterization of a mammographic system based on single photon counting pixel arrays coupled to GaAs x-ray detectors.

    abstract::The authors report on the imaging capabilities of a mammographic system demonstrator based on GaAs pixel detectors operating in single photon counting (SPC) mode. The system imaging performances have been assessed by means of the transfer functions: The modulation transfer function (MTF), the normalized noise power sp...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3097284

    authors: Amendolia SR,Bisogni MG,Delogu P,Fantacci ME,Paternoster G,Rosso V,Stefanini A

    更新日期:2009-04-01 00:00:00

  • Approaches to calculating AAPM TG-43 brachytherapy dosimetry parameters for 137Cs, 125I, 192Ir, 103Pd, and 169Yb sources.

    abstract::Underlying characteristics in brachytherapy dosimetry parameters for medical radionuclides 137Cs, 125I, 192Ir, 103Pd, and 169Yb were examined using Monte Carlo methods. Sources were modeled as unencapsulated point or line sources in liquid water to negate variations due to materials and construction. Importance of pha...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2199987

    authors: Melhus CS,Rivard MJ

    更新日期:2006-06-01 00:00:00

  • Transverse tomosynthesis on a digital simulator.

    abstract::The availability of digital radiographic imaging on simulators has led to the investigation of a number of new imaging possibilities, including digital linear tomography (tomosynthesis). It has been shown that a single set of projections in this case is sufficient to reconstruct images from multiple planes, including ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598006

    authors: Zwicker RD,Atari NA

    更新日期:1997-06-01 00:00:00

  • Radiofrequency transmit calibration: A multi-center evaluation of vendor-provided radiofrequency transmit mapping methods.

    abstract:PURPOSE:To determine the accuracy and test-retest repeatability of fast radiofrequency (RF) transmit measurement approaches used in Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI). Spatial variation in the transmitted RF field introduces bias and increased variance in quantitative DCE-MRI metrics includi...

    journal_title:Medical physics

    pub_type: 杂志文章,多中心研究

    doi:10.1002/mp.13518

    authors: Bliesener Y,Zhong X,Guo Y,Boss M,Bosca R,Laue H,Chung C,Sung K,Nayak KS

    更新日期:2019-06-01 00:00:00

  • Combined kV and MV imaging for real-time tracking of implanted fiducial markers.

    abstract::In the presence of intrafraction organ motion, target localization uncertainty can greatly hamper the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT). To minimize the adverse dosimetric effect caused by tumor motion, a real-time knowledge of the tumor position is requ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2842072

    authors: Wiersma RD,Mao W,Xing L

    更新日期:2008-04-01 00:00:00

  • A new open-source GPU-based microscopic Monte Carlo simulation tool for the calculations of DNA damages caused by ionizing radiation - Part II: sensitivity and uncertainty analysis.

    abstract:PURPOSE:Calculations of deoxyribonucleic acid (DNA) damages involve many parameters in the computation process. As these parameters are often subject to uncertainties, it is of central importance to comprehensively quantify their impacts on DNA single-strand break (SSB) and double-strand break (DSB) yields. This has be...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14036

    authors: Lai Y,Tsai MY,Tian Z,Qin N,Yan C,Hung SH,Chi Y,Jia X

    更新日期:2020-04-01 00:00:00

  • TU-D-213AB-01: How You Can Be the Speaker and Communicator Everyone Wants You to Be.

    abstract::Effectiveness of an oral presentation depends on the ability of the speaker to communicate with the audience. An important part of this communication is focusing on two to five key points and emphasizing those points during the presentation. Every aspect of the presentation should be purposeful and directed at facilit...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735944

    authors: Collins J,Aydogan B

    更新日期:2012-06-01 00:00:00