Abstract：
OBJECTIVE:Numerous studies have identified different predictors for secondary hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH), although predictors regarding timing of the shunt operation have never been reported. Predictors for an early shunt, which was defined as a shunt operation performed ≤30 days after SAH onset, and for a late shunt, performed at >40 days, were investigated. METHODS:A total of 735 consecutive SAH patients admitted to our hospital between 2003 and 2014 who underwent surgery for ruptured aneurysms within five days of onset were retrospectively assessed. RESULTS:Secondary hydrocephalus developed in 225 patients, including 70 with an early shunt and 96 with a late shunt. Multivariate analysis showed that predictors for secondary hydrocephalus were age ≥70 years, World Federation of Neurosurgical Society (WFNS) grade IV-V, Fisher grade 3-4, intraventricular hemorrhage, anterior cerebral artery aneurysms, and external drainage for acute hydrocephalus (p < 0.05). In the early and late shunt groups, multivariate analysis indicated that early shunt was significantly associated with coil embolization, and late shunt was correlated with middle cerebral artery aneurysms and cerebral infarction due to vasospasm (p < 0.05). DISCUSSION:The difference in the predictors between the early and late shunts implied that the mechanisms of secondary hydrocephalus differed between the early and late shunt groups. Knowledge of the associated risk factors might help to predict the timing of the shunt operation for early rehabilitation planning in the future.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Shigematsu H,Sorimachi T,Osada T,Aoki R,Srivatanakul K,Oda S,Matsumae Mdoi
10.1080/01616412.2016.1199184subject
Has Abstractpub_date
2016-07-01 00:00:00pages
600-5issue
7eissn
0161-6412issn
1743-1328journal_volume
38pub_type
杂志文章abstract：OBJECTIVE:Repetitive magnetic stimulation (rMS) is mainly used in transcranial applications. Only a few works have described its potential peripheral use. The aim of this investigation was to determine if conditioning peripheral (paravertebral) rMS of the cervical nerve roots in a group of healthy subjects induces chan...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/174313208X297959
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVES:To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS. METHODS:Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital ...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2020.1792700
更新日期：2020-11-01 00:00:00
abstract：:The objective was to examine the effect of the nitric oxide synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME) on leukocyte adhesion in the cerebral microcirculation during reperfusion following partial forebrain ischemia in the rat. Intravital fluorescence video-microscopy through a closed cranial win...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1999.11740947
更新日期：1999-06-01 00:00:00
abstract：:Rats were exposed in utero plus 60 days post-partum to either complex music (Mozart Sonata (k. 448)), minimalist music (a Philip Glass composition), white noise or silence, and were then tested for five days, three trials per day, in a multiple T-maze. By Day 3, the rats exposed to the Mozart work completed the maze m...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1998.11740543
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVES:Microglial cells in spinal dorsal horn can be activated by nociceptive stimuli and the activated microglial cells release various cytokines enhancing the nociceptive transmission. However, the mechanisms underlying the activation of spinal microglia during nociceptive stimuli have not been well understood. I...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2017.1281198
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...
journal_title：Neurological research
pub_type： 杂志文章,评审
doi：10.1179/016164110X12644252260592
更新日期：2010-04-01 00:00:00
abstract：:Analysis of the blood flow velocities in the middle cerebral artery by transcranial Doppler ultrasonography was performed in 158 healthy volunteers (aged 14-70 years; 82 men and 76 women). In a subgroup of 38 men and 21 women the end-tidal [CO2] was also measured. The influence of biological factors such as age, sex, ...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1990.11739941
更新日期：1990-09-01 00:00:00
abstract：:Induction of stress proteins is thought to be important in the protection of cells from a variety of environmental insults including heat, hypoxia and ischemia. The aim of this study was to compare the mechanism of induction of heat shock protein 72 (HSP72) in primary cultures of murine cortical astrocytes by heat and...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1996.11740380
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:This study intends to investigate the prognostic value of perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage. METHODS:Demographic, clinical and biochemical data between acute intracerebral hemorrhage (AICH) and healthy volunteer groups were assessed in this study, such as rCBV an...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2016.1177932
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:Current chemotherapy treatments available for treating high-grade brain tumors, Temozolomide (TMZ) or Bevacizumab (BEV), not only have specific anti-tumor mechanisms, but also have an effect on mitochondria. However, effects of both drugs on mitochondria isolated from human brain tumors have not been thorough...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2015.1114233
更新日期：2016-04-01 00:00:00
abstract：:An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1980.11739588
更新日期：1980-01-01 00:00:00
abstract：OBJECTIVE:To investigate the clinical application of adjuvant coiling techniques in treating anterior-circulation wide-necked aneurysms. METHODS:Over 4·5 years, 93 anterior-circulation wide-neck aneurysms in 81 patients were treated with different endovascular techniques: balloon-assisted, stent-assisted, and double-m...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/1743132813Y.0000000234
更新日期：2013-12-01 00:00:00
abstract：:The effect of labetalol, a combined alpha- and beta-adrenoceptor antagonist, on the cerebral circulation was investigated in 7 normotensive subjects. Cerebral blood flow (CBF) was measured with the intravenous 133Xe method and mean flow velocity (Vmean) in the middle cerebral artery was determined using transcranial D...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1991.11739958
更新日期：1991-03-01 00:00:00
abstract：:Ahead of Print article withdrawn by publisher. ...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/016164109X12445616596283
更新日期：2009-08-21 00:00:00
abstract：:The selection of drugs to prevent the development of pathology in cerebral infarction remains an important problem. For the selection of effective drugs from among a large number of possible candidates, widely-used test screening techniques are sufficient for obtaining a good understanding of candidate drug effects. T...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1988.11739810
更新日期：1988-03-01 00:00:00
abstract：:A computer software program (Seapit) was developed for precise determination of intracranial targets identified by stereotactic computed tomography (CT). This program was added to the software of a GE 8800 CT scanner to perform the following operations: millimetre precise calculation and display of the rectilinear coo...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1987.11739781
更新日期：1987-06-01 00:00:00
abstract：OBJECTIVE:Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated. ...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/174313209X385617
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVES:Parkinson's disease (PD) afflicts approximately 1-2% of the population over 50 years of age. No cures or effective modifying treatments exist and clinical diagnosis is currently confounded by a lack of definitive biomarkers. We sought to discover potential biomarkers in the cerebrospinal fluid (CSF) of neuro...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/1743132812Y.0000000063
更新日期：2012-09-01 00:00:00
abstract：:This study was performed to test whether GYKI 52466, a nonNMDA receptor antagonist, would improve microregional oxygen supply and consumption balance in the focal cerebral ischemic area. Rats were anesthetized with 1.4% isoflurane. For the GYKI Group (n = 8), 10 min before middle cerebral artery (MCA) occlusion, a bol...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1999.11740935
更新日期：1999-04-01 00:00:00
abstract：:Using the previously reported method of experimental localized brainstem infarct in dogs, we designed this study to elucidate sequential changes of regional cerebral blood flow (rCBF) in three separate regions of the central nervous system: the cerebral cortex, thalamus, and midbrain. The data obtained were referred t...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2000.11741061
更新日期：2000-03-01 00:00:00
abstract：:Corticotrophin releasing factor has been shown in several models of tissue injury to be an effective treatment for edema. In a previous study we demonstrated this ability in two models of traumatic brain injury (TBI). The aim of this study was to assess whether human corticotrophin releasing factor (hCRF) could additi...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2000.11740737
更新日期：2000-10-01 00:00:00
abstract：:Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1993.11740174
更新日期：1993-12-01 00:00:00
abstract：:Intravenous infusion of glycerol has been used in patients with a cerebral infarction, expecting improvement in brain edema and cerebral blood flow (CBF). However, the mechanism of the improvement of CBF has not been clearly demonstrated. The aim of this study in the rat pial microvasculature after transient middle ce...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.1999.11741015
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVES:In multiple sclerosis (MS) demyelination occurs in both white and gray matter. Here we introduce an electrophysiological approach for studying functional demyelination and myelin repair in rat hippocampus, a gray matter structure, which is frequently affected in patients suffering from MS. METHODS:Using a s...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/1743132813Y.0000000221
更新日期：2013-10-01 00:00:00
abstract：:Background Transtemporal Doppler (TTD) with middle cerebral artery (MCA) is widely used for right-to-left shunt (RLS) detection. However, an alternative method for patients without suitable temporal bone windows should be established. The present study prospectively evaluated the effectiveness of transorbital Doppler ...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2018.1428276
更新日期：2018-03-01 00:00:00
abstract：:Objectives: Brain arteriovenous malformations (AVMs) represent high-flow vascular lesions made up of a complex network of feeding arteries and draining veins interposed by a nidus and without a capillary bed. The management of the AVMs represents a challenge, and the optimal treatment should be considered based on the...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2020.1803604
更新日期：2020-12-01 00:00:00
abstract：:Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2019.1685064
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:Catalpol has been identified to have neuroprotective effect on gerbils subjected to transient global cerebral ischemia. However, the mechanism that catalpol prevents ischemia is still unclear. In the present study, PC12 cells, exposed to oxygen and glucose deprivation (OGD) followed by reperfusion, were used...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/016164107X229894
更新日期：2008-02-01 00:00:00
abstract：:The decrease in intracellular creatine concentration in Duchenne muscular dystrophy may contribute to the deterioration of intracellular energy homeostasis and may thus be one of the factors aggravating muscle weakness and degeneration. Oral creatine supplementation should have potential in alleviating the clinical sy...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1080/01616412.2000.11741051
更新日期：2000-03-01 00:00:00
abstract：:Mild vascular cognitive impairment (mVCI) is a broader term that is intended to detect cognitive loss before the development of dementia. The identification of preventable risk factors as well as therapeutic strategies of intervention is still unclear. It has been suggested that carotid endarterectomy (CEA) improves c...
journal_title：Neurological research
pub_type： 杂志文章
doi：10.1179/016164104225016245
更新日期：2004-07-01 00:00:00
