Distinct distributed patterns of neural activity are associated with two languages in the bilingual brain.

abstract：:Six percent of Americans, including 3 million high schoolers, use e-cigarettes, which contain potentially toxic substances, volatile organic compounds, and metals. We present the first human study on the effects of e-cigarette exposure in the oral cavity. By interrogating both immunoinflammatory responses and microbia...

journal_title：Science advances

authors： Ganesan SM,Dabdoub SM,Nagaraja HN,Scott ML,Pamulapati S,Berman ML,Shields PG,Wewers ME,Kumar PS

更新日期：2020-05-27 00:00:00

abstract：:Many insects use nectar as their principal diet and have mouthparts specialized in nectarivory, whereas most nectar-feeding vertebrates are opportunistic users of floral resources and only a few species show distinct morphological specializations. Specialized nectar-feeding bats extract nectar from flowers using elong...

journal_title：Science advances

authors： Tschapka M,Gonzalez-Terrazas TP,Knörnschild M

更新日期：2015-09-25 00:00:00

abstract：:The Rashba physics has been intensively studied in the field of spin orbitronics for the purpose of searching novel physical properties and the ferromagnetic (FM) magnetization switching for technological applications. We report our observation of the inverse Edelstein effect up to room temperature in the Rashba-split...

journal_title：Science advances

authors： Song Q,Zhang H,Su T,Yuan W,Chen Y,Xing W,Shi J,Sun J,Han W

更新日期：2017-03-17 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is life-threatening because of limited therapies and lack of effective therapeutic targets. Here, we found that moesin (MSN) was significantly overexpressed in TNBC compared with other subtypes of breast cancer and was positively correlated with poor overall survival. However, litt...

journal_title：Science advances

authors： Qin Y,Chen W,Jiang G,Zhou L,Yang X,Li H,He X,Wang HL,Zhou YB,Huang S,Liu S

更新日期：2020-02-19 00:00:00

abstract：:Changes in extreme weather, such as tropical cyclones, are one of the most serious ways society experiences the impact of climate change. Advance forecasted conditional attribution statements, using a numerical model, were made about the anthropogenic climate change influence on an individual tropical cyclone, Hurrica...

journal_title：Science advances

authors： Reed KA,Stansfield AM,Wehner MF,Zarzycki CM

更新日期：2020-01-01 00:00:00

abstract：:Skyrmions are topologically protected nanoscale magnetic spin entities in helical magnets. They behave like particles and tend to form hexagonal close-packed lattices, like atoms, as their stable structure. Domain boundaries in skyrmion lattices are considered to be important as they affect the dynamic properties of m...

journal_title：Science advances

authors： Matsumoto T,So YG,Kohno Y,Sawada H,Ikuhara Y,Shibata N

更新日期：2016-02-12 00:00:00

abstract：:Immune regulatory metabolites are key features of the tumor microenvironment (TME), yet with a few exceptions, their identities remain largely unknown. Here, we profiled tumor and T cells from tumor and ascites of patients with high-grade serous carcinoma (HGSC) to uncover the metabolomes of these distinct TME compart...

journal_title：Science advances

authors： Kilgour MK,MacPherson S,Zacharias LG,Ellis AE,Sheldon RD,Liu EY,Keyes S,Pauly B,Carleton G,Allard B,Smazynski J,Williams KS,Watson PH,Stagg J,Nelson BH,DeBerardinis RJ,Jones RG,Hamilton PT,Lum JJ

更新日期：2021-01-20 00:00:00

abstract：:Biodiversity loss is a social and ecological emergency, and calls have been made for the global expansion of protected areas (PAs) to tackle this crisis. It is unclear, however, where best to locate new PAs to protect biodiversity cost-effectively. To answer this question, we conducted a spatial meta-analysis by overl...

journal_title：Science advances

authors： Yang R,Cao Y,Hou S,Peng Q,Wang X,Wang F,Tseng TH,Yu L,Carver S,Convery I,Zhao Z,Shen X,Li S,Zheng Y,Liu H,Gong P,Ma K

更新日期：2020-09-09 00:00:00

abstract：:Despite the potential of photodynamic therapy (PDT), its comprehensive use in cancer treatment has not been achieved because of the nondegradable risks of photosensitizing drugs and limits of light penetration and instrumentation. Here, we present bioluminescence (BL)-induced proteinaceous PDT (BLiP-PDT), through the ...

journal_title：Science advances

authors： Kim EH,Park S,Kim YK,Moon M,Park J,Lee KJ,Lee S,Kim YP

更新日期：2020-09-11 00:00:00

abstract：:The impact of the FMR1 premutation on human health is the subject of considerable controversy. A fundamental unanswered question is whether carrying the premutation allele is directly correlated with clinical phenotypes. A challenging problem in past genotype-phenotype studies of the FMR1 premutation is ascertainment ...

journal_title：Science advances

authors： Movaghar A,Page D,Brilliant M,Baker MW,Greenberg J,Hong J,DaWalt LS,Saha K,Kuusisto F,Stewart R,Berry-Kravis E,Mailick MR

更新日期：2019-08-21 00:00:00

abstract：:Nanoparticles have been extensively used for inflammation imaging and photodynamic therapy of cancer. However, the major translational barriers to most nanoparticle-based imaging and therapy applications are the limited depth of tissue penetration, inevitable requirement of external irradiation, and poor biocompatibil...

journal_title：Science advances

authors： Xu X,An H,Zhang D,Tao H,Dou Y,Li X,Huang J,Zhang J

更新日期：2019-01-09 00:00:00

abstract：:A new set of time-of-day-dependent global maps of the lunar near-infrared water/hydroxyl (H2O/OH) absorption band strength near 2.8 to 3.0 μm constructed on the basis of Moon Mineralogy Mapper (M3) data is presented. The analyzed absorption band near 2.8 to 3.0 μm indicates the presence of surficial H2O/OH. To remove ...

journal_title：Science advances

authors： Wöhler C,Grumpe A,Berezhnoy AA,Shevchenko VV

更新日期：2017-09-08 00:00:00

abstract：:Ice-templating holds promise to become a powerful technique to construct high-performance bioinspired materials. Both ice nucleation and growth during the freezing process are crucial for the final architecture of the ice-templated material. However, effective ways to control these two very important factors are still...

journal_title：Science advances

authors： Zhao N,Li M,Gong H,Bai H

更新日期：2020-07-31 00:00:00

abstract：:The discovery of high-temperature superconductivity in cuprates ranks among the major scientific milestones of the past half century, yet pivotal questions regarding the complex phase diagram of these materials remain unanswered. Generally thought of as doped charge-transfer insulators, these complex oxides exhibit ps...

journal_title：Science advances

authors： Pelc D,Popčević P,Požek M,Greven M,Barišić N

更新日期：2019-01-25 00:00:00

abstract：:Analog machine learning hardware platforms promise to be faster and more energy efficient than their digital counterparts. Wave physics, as found in acoustics and optics, is a natural candidate for building analog processors for time-varying signals. Here, we identify a mapping between the dynamics of wave physics and...

journal_title：Science advances

authors： Hughes TW,Williamson IAD,Minkov M,Fan S

更新日期：2019-12-20 00:00:00

abstract：:A semiconductor nanowire with strong spin-orbit coupling in proximity to a superconductor is predicted to display Majorana edge states emerging under a properly oriented magnetic field. The experimental investigation of these exotic states requires assessing the one-dimensional (1D) character of the nanowire and under...

journal_title：Science advances

authors： Estrada Saldaña JC,Žitko R,Cleuziou JP,Lee EJH,Zannier V,Ercolani D,Sorba L,Aguado R,De Franceschi S

更新日期：2019-07-05 00:00:00

abstract：:Black phosphorus (BP) offers considerable promise for infrared and visible photonics. Efficient tuning of the bandgap and higher subbands in BP by modulation of the Fermi level or application of vertical electric fields has been previously demonstrated, allowing electrical control of its above-bandgap optical properti...

journal_title：Science advances

authors： Biswas S,Whitney WS,Grajower MY,Watanabe K,Taniguchi T,Bechtel HA,Rossman GR,Atwater HA

更新日期：2021-01-08 00:00:00

abstract：:Understanding the precise atomic structure of ice surfaces is critical for revealing the mechanisms of physical and chemical phenomena at the surfaces, such as ice growth, melting, and chemical reactions. Nevertheless, no conclusive structure has been established. In this study, noncontact atomic force microscopy was ...

journal_title：Science advances

authors： Kawakami N,Iwata K,Shiotari A,Sugimoto Y

更新日期：2020-09-11 00:00:00

abstract：:Fibrosis, characterized by aberrant tissue scarring from activated myofibroblasts, is often untreatable. Although the extracellular matrix becomes increasingly stiff and fibrous during disease progression, how these physical cues affect myofibroblast differentiation in 3D is poorly understood. Here, we describe a mult...

journal_title：Science advances

authors： Matera DL,DiLillo KM,Smith MR,Davidson CD,Parikh R,Said M,Wilke CA,Lombaert IM,Arnold KB,Moore BB,Baker BM

更新日期：2020-09-09 00:00:00

abstract：:In mammals, the daily rhythms of physiological functions are timed by the central circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Although the importance of the SCN for the regulation of sleep/wakefulness has been suggested, little is known about the neuronal projections from the SCN,...

journal_title：Science advances

authors： Ono D,Mukai Y,Hung CJ,Chowdhury S,Sugiyama T,Yamanaka A

更新日期：2020-11-06 00:00:00

abstract：:The Paris Agreement aims to mitigate the potential impacts of climate change on ecological and social systems. Using an ensemble of climate-marine ecosystem and economic models, we explore the effects of implementing the Agreement on fish, fishers, and seafood consumers worldwide. We find that implementing the Agreeme...

journal_title：Science advances

authors： Sumaila UR,Tai TC,Lam VWY,Cheung WWL,Bailey M,Cisneros-Montemayor AM,Chen OL,Gulati SS

更新日期：2019-02-27 00:00:00

abstract：:B cell activation is regulated by the stimulatory or inhibitory co-receptors of B cell receptors (BCRs). Here, we investigated the signaling mechanism of Fc receptor-like 1 (FcRL1), a newly identified BCR co-receptor. FcRL1 was passively recruited into B cell immunological synapses upon BCR engagement in the absence o...

journal_title：Science advances

authors： Zhao X,Xie H,Zhao M,Ahsan A,Li X,Wang F,Yi J,Yang Z,Wu C,Raman I,Li QZ,Kim TJ,Liu W

更新日期：2019-07-17 00:00:00

abstract：:Low-dimensional perovskites offer a rare opportunity to investigate lattice dynamics and charge carrier behavior in bulk quantum-confined solids, in addition to them being the leading materials in optoelectronic applications. In particular, zero-dimensional (0D) inorganic perovskites of the Cs4PbX6 (X = Cl, Br, or I) ...

journal_title：Science advances

authors： Yin J,Maity P,De Bastiani M,Dursun I,Bakr OM,Brédas JL,Mohammed OF

更新日期：2017-12-15 00:00:00

abstract：:Nitrogen oxides (NO x = NO + NO2) are a primary component of air pollution-a leading cause of premature death in humans and biodiversity declines worldwide. Although regulatory policies in California have successfully limited transportation sources of NO ...

journal_title：Science advances

authors： Almaraz M,Bai E,Wang C,Trousdell J,Conley S,Faloona I,Houlton BZ

更新日期：2018-01-31 00:00:00

abstract：:We develop biohybrid magnetic microrobots by electrostatic self-assembly of nonmotile sperm cells and magnetic nanoparticles. Incorporating a biological entity into microrobots entails many functional advantages beyond shape templating, such as the facile uptake of chemotherapeutic agents to achieve targeted drug deli...

journal_title：Science advances

authors： Magdanz V,Khalil ISM,Simmchen J,Furtado GP,Mohanty S,Gebauer J,Xu H,Klingner A,Aziz A,Medina-Sánchez M,Schmidt OG,Misra S

更新日期：2020-07-08 00:00:00

abstract：:Hydroxyapatite (HA) has been widely applied in bone repair because of its superior biocompatibility. Recently, a proliferation-suppressive effect of HA nanoparticles (n-HA) against various cancer cells was reported. This study was aimed at assessing the translational value of n-HA both as a bone-regenerating material ...

journal_title：Science advances

authors： Zhang K,Zhou Y,Xiao C,Zhao W,Wu H,Tang J,Li Z,Yu S,Li X,Min L,Yu Z,Wang G,Wang L,Zhang K,Yang X,Zhu X,Tu C,Zhang X

更新日期：2019-08-02 00:00:00

abstract：:Double seismic zones are two-layered distributions of intermediate-depth earthquakes that provide insight into the thermomechanical state of subducting slabs. We present new precise hypocenters of intermediate-depth earthquakes in the Tonga subduction zone obtained using data from local island-based, ocean-bottom, and...

journal_title：Science advances

authors： Wei SS,Wiens DA,van Keken PE,Cai C

更新日期：2017-01-11 00:00:00

abstract：:Pressure is a key parameter in the physics and chemistry of planet formation and evolution. Previous studies have erroneously assumed that internal pressures monotonically increase with the mass of a body. Using smoothed particle hydrodynamics and potential field method calculations, we demonstrate that the hot, rapid...

journal_title：Science advances

authors： Lock SJ,Stewart ST

更新日期：2019-09-04 00:00:00

abstract：:Calcium silicate hydrate (C-S-H) is the binder in concrete, the most used synthetic material in the world. The main weakness of concrete is the lack of elasticity and poor flexural strength considerably limiting its potential, making reinforcing steel constructions necessary. Although the properties of C-S-H could be ...

journal_title：Science advances

authors： Picker A,Nicoleau L,Burghard Z,Bill J,Zlotnikov I,Labbez C,Nonat A,Cölfen H

更新日期：2017-11-29 00:00:00

abstract：:The transcription factor p63 is a key mediator of epidermal development. Point mutations in p63 in patients lead to developmental defects, including orofacial clefting. To date, knowledge on how pivotal the role of p63 is in human craniofacial development is limited. Using an inducible transdifferentiation model, comb...

journal_title：Science advances

authors： Lin-Shiao E,Lan Y,Welzenbach J,Alexander KA,Zhang Z,Knapp M,Mangold E,Sammons M,Ludwig KU,Berger SL

更新日期：2019-05-01 00:00:00