Slab temperature controls on the Tonga double seismic zone and slab mantle dehydration.


:Double seismic zones are two-layered distributions of intermediate-depth earthquakes that provide insight into the thermomechanical state of subducting slabs. We present new precise hypocenters of intermediate-depth earthquakes in the Tonga subduction zone obtained using data from local island-based, ocean-bottom, and global seismographs. The results show a downdip compressional upper plane and a downdip tensional lower plane with a separation of about 30 km. The double seismic zone in Tonga extends to a depth of about 300 km, deeper than in any other subduction system. This is due to the lower slab temperatures resulting from faster subduction, as indicated by a global trend toward deeper double seismic zones in colder slabs. In addition, a line of high seismicity in the upper plane is observed at a depth of 160 to 280 km, which shallows southward as the convergence rate decreases. Thermal modeling shows that the earthquakes in this "seismic belt" occur at various pressures but at a nearly constant temperature, highlighting the important role of temperature in triggering intermediate-depth earthquakes. This seismic belt may correspond to regions where the subducting mantle first reaches a temperature of ~500°C, implying that metamorphic dehydration of mantle minerals in the slab provides water to enhance faulting.


Sci Adv


Science advances


Wei SS,Wiens DA,van Keken PE,Cai C




Has Abstract


2017-01-11 00:00:00












  • Direct metabolite detection with an n-type accumulation mode organic electrochemical transistor.

    abstract::The inherent specificity and electrochemical reversibility of enzymes poise them as the biorecognition element of choice for a wide range of metabolites. To use enzymes efficiently in biosensors, the redox centers of the protein should have good electrical communication with the transducing electrode, which requires e...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Pappa AM,Ohayon D,Giovannitti A,Maria IP,Savva A,Uguz I,Rivnay J,McCulloch I,Owens RM,Inal S

    更新日期:2018-06-22 00:00:00

  • Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota.

    abstract::Ascomycota, the largest and most well-studied phylum of fungi, contains three subphyla: Saccharomycotina (budding yeasts), Pezizomycotina (filamentous fungi), and Taphrinomycotina (fission yeasts). Despite its importance, we lack a comprehensive genome-scale phylogeny or understanding of the similarities and differenc...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Shen XX,Steenwyk JL,LaBella AL,Opulente DA,Zhou X,Kominek J,Li Y,Groenewald M,Hittinger CT,Rokas A

    更新日期:2020-11-04 00:00:00

  • Multiplexed oscillations and phase rate coding in the basal forebrain.

    abstract::Complex behaviors demand temporal coordination among functionally distinct brain regions. The basal forebrain's afferent and efferent structure suggests a capacity for mediating this coordination at a large scale. During performance of a spatial orientation task, synaptic activity in this region was dominated by four ...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Tingley D,Alexander AS,Quinn LK,Chiba AA,Nitz D

    更新日期:2018-08-01 00:00:00

  • Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect.

    abstract::This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetric synthesis. The carbafructopyranosyl-1,2-diamine(s) and salens constructed therefrom are particularly compelling. It is shown that by removing the native anomeric effect...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Karukurichi KR,Fei X,Swyka RA,Broussy S,Shen W,Dey S,Roy SK,Berkowitz DB

    更新日期:2015-07-01 00:00:00

  • Biomimetic enzyme cascade reaction system in microfluidic electrospray microcapsules.

    abstract::Mimicking subcellular compartments containing enzymes in organisms is considered a promising approach to substitute for missing or lost cellular functions. Inspired by the multicompartment structures of cellular architectures, we present a novel multienzyme system based on hollow hydrogel microcapsules with flexible e...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Wang H,Zhao Z,Liu Y,Shao C,Bian F,Zhao Y

    更新日期:2018-06-15 00:00:00

  • Persistent collapse of biomass in Amazonian forest edges following deforestation leads to unaccounted carbon losses.

    abstract::Deforestation is the primary driver of carbon losses in tropical forests, but it does not operate alone. Forest fragmentation, a resulting feature of the deforestation process, promotes indirect carbon losses induced by edge effect. This process is not implicitly considered by policies for reducing carbon emissions in...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Silva Junior CHL,Aragão LEOC,Anderson LO,Fonseca MG,Shimabukuro YE,Vancutsem C,Achard F,Beuchle R,Numata I,Silva CA,Maeda EE,Longo M,Saatchi SS

    更新日期:2020-09-30 00:00:00

  • A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target.

    abstract::G-quadruplex (G4) is one of the most important secondary structures in nucleic acids. Until recently, G4 RNAs have not been reported in any ribovirus, such as the hepatitis C virus. Our bioinformatics analysis reveals highly conserved guanine-rich consensus sequences within the core gene of hepatitis C despite the hig...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Wang SR,Min YQ,Wang JQ,Liu CX,Fu BS,Wu F,Wu LY,Qiao ZX,Song YY,Xu GH,Wu ZG,Huang G,Peng NF,Huang R,Mao WX,Peng S,Chen YQ,Zhu Y,Tian T,Zhang XL,Zhou X

    更新日期:2016-04-01 00:00:00

  • Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes.

    abstract::A trimer-of-hairpins motif has been identified in triggering virus-cell fusion within a variety of viral envelopes. Chemically manipulating such a motif represents current repertoire of viral fusion inhibitors. Here, we report that triterpenoids, a class of natural products, antagonize this trimer-of-hairpins via its ...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Si L,Meng K,Tian Z,Sun J,Li H,Zhang Z,Soloveva V,Li H,Fu G,Xia Q,Xiao S,Zhang L,Zhou D

    更新日期:2018-11-21 00:00:00

  • Molecular parallelism in fast-twitch muscle proteins in echolocating mammals.

    abstract::Detecting associations between genomic changes and phenotypic differences is fundamental to understanding how phenotypes evolved. By systematically screening for parallel amino acid substitutions, we detected known as well as novel cases (Strc, Tecta, and Cabp2) of parallelism between echolocating bats and toothed wha...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Lee JH,Lewis KM,Moural TW,Kirilenko B,Borgonovo B,Prange G,Koessl M,Huggenberger S,Kang C,Hiller M

    更新日期:2018-09-26 00:00:00

  • Dual pH-sensitive nanodrug blocks PD-1 immune checkpoint and uses T cells to deliver NF-κB inhibitor for antitumor immunotherapy.

    abstract::The response to programmed cell death protein-1 (PD-1)/programmed death ligand-1 (PD-L1) blockade in cancer immunotherapy is limited because of multiple immune evasion mechanisms. Here, a previously unknown strategy is proposed to synergize the nuclear factor κB (NF-κB) inhibition and PD-1 blockade for antitumor immun...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Xiao Z,Su Z,Han S,Huang J,Lin L,Shuai X

    更新日期:2020-02-05 00:00:00

  • A single iron site confined in a graphene matrix for the catalytic oxidation of benzene at room temperature.

    abstract::Coordinatively unsaturated (CUS) iron sites are highly active in catalytic oxidation reactions; however, maintaining the CUS structure of iron during heterogeneous catalytic reactions is a great challenge. Here, we report a strategy to stabilize single-atom CUS iron sites by embedding highly dispersed FeN4 centers in ...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Deng D,Chen X,Yu L,Wu X,Liu Q,Liu Y,Yang H,Tian H,Hu Y,Du P,Si R,Wang J,Cui X,Li H,Xiao J,Xu T,Deng J,Yang F,Duchesne PN,Zhang P,Zhou J,Sun L,Li J,Pan X,Bao X

    更新日期:2015-12-04 00:00:00

  • Data-driven phenotype discovery of FMR1 premutation carriers in a population-based sample.

    abstract::The impact of the FMR1 premutation on human health is the subject of considerable controversy. A fundamental unanswered question is whether carrying the premutation allele is directly correlated with clinical phenotypes. A challenging problem in past genotype-phenotype studies of the FMR1 premutation is ascertainment ...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Movaghar A,Page D,Brilliant M,Baker MW,Greenberg J,Hong J,DaWalt LS,Saha K,Kuusisto F,Stewart R,Berry-Kravis E,Mailick MR

    更新日期:2019-08-21 00:00:00

  • Acupuncture attenuates alcohol dependence through activation of endorphinergic input to the nucleus accumbens from the arcuate nucleus.

    abstract::A withdrawal-associated impairment in β-endorphin neurotransmission in the arcuate nucleus (ARC) of the hypothalamus is associated with alcohol dependence characterized by a chronic relapsing disorder. Although acupuncture activates β-endorphin neurons in the ARC projecting to the nucleus accumbens (NAc), a role for A...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Chang S,Kim DH,Jang EY,Yoon SS,Gwak YS,Yi YJ,Lee JY,Ahn SH,Kim JM,Ryu YH,Kim SN,Roh HS,Lee MY,Kim SC,Lee BH,Kim HY,Yang CH

    更新日期:2019-09-04 00:00:00

  • pH-dependent gating mechanism of the Helicobacter pylori urea channel revealed by cryo-EM.

    abstract::The urea channel of Helicobacterpylori (HpUreI) is an ideal drug target for preventing gastric cancer but incomplete understanding of its gating mechanism has hampered development of inhibitors for the eradication of H. pylori. Here, we present the cryo-EM structures of HpUreI in closed and open conformations, both at...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Cui Y,Zhou K,Strugatsky D,Wen Y,Sachs G,Zhou ZH,Munson K

    更新日期:2019-03-20 00:00:00

  • PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.

    abstract::Holoprosencephaly (HPE) is a congenital forebrain defect often associated with embryonic lethality and lifelong disabilities. Currently, therapeutic and diagnostic options are limited by lack of knowledge of potential disease-causing mutations. We have identified a new mutation in the PRDM15 gene (C844Y) associated wi...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Mzoughi S,Di Tullio F,Low DHP,Motofeanu CM,Ong SLM,Wollmann H,Wun CM,Kruszka P,Muenke M,Hildebrandt F,Dunn NR,Messerschmidt DM,Guccione E

    更新日期:2020-01-10 00:00:00

  • Giant Rashba splitting in 2D organic-inorganic halide perovskites measured by transient spectroscopies.

    abstract::Two-dimensional (2D) layered hybrid organic-inorganic halide perovskite semiconductors form natural "multiple quantum wells" that have strong spin-orbit coupling due to the heavy elements in their building blocks. This may lead to "Rashba splitting" close to the extrema in the electron bands. We have used a plethora o...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Zhai Y,Baniya S,Zhang C,Li J,Haney P,Sheng CX,Ehrenfreund E,Vardeny ZV

    更新日期:2017-07-28 00:00:00

  • Designing durable icephobic surfaces.

    abstract::Ice accretion has a negative impact on critical infrastructure, as well as a range of commercial and residential activities. Icephobic surfaces are defined by an ice adhesion strength τice < 100 kPa. However, the passive removal of ice requires much lower values of τice, such as on airplane wings or power lines (τice ...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Golovin K,Kobaku SP,Lee DH,DiLoreto ET,Mabry JM,Tuteja A

    更新日期:2016-03-11 00:00:00

  • Arginine methylation expands the regulatory mechanisms and extends the genomic landscape under E2F control.

    abstract::E2F is a family of master transcription regulators involved in mediating diverse cell fates. Here, we show that residue-specific arginine methylation (meR) by PRMT5 enables E2F1 to regulate many genes at the level of alternative RNA splicing, rather than through its classical transcription-based mechanism. The p100/TS...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Roworth AP,Carr SM,Liu G,Barczak W,Miller RL,Munro S,Kanapin A,Samsonova A,La Thangue NB

    更新日期:2019-06-26 00:00:00

  • Real-time probing of granular dynamics with magnetic resonance.

    abstract::Granular dynamics govern earthquakes, avalanches, and landslides and are of fundamental importance in a variety of industries ranging from energy to pharmaceuticals to agriculture. Nonetheless, our understanding of the underlying physics is poor because we lack spatially and temporally resolved experimental measuremen...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Penn A,Tsuji T,Brunner DO,Boyce CM,Pruessmann KP,Müller CR

    更新日期:2017-09-15 00:00:00

  • Focal infrared neural stimulation with high-field functional MRI: A rapid way to map mesoscale brain connectomes.

    abstract::We have developed a way to map brain-wide networks using focal pulsed infrared neural stimulation in ultrahigh-field magnetic resonance imaging (MRI). The patterns of connections revealed are similar to those of connections previously mapped with anatomical tract tracing methods. These include connections between cort...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Xu AG,Qian M,Tian F,Xu B,Friedman RM,Wang J,Song X,Sun Y,Chernov MM,Cayce JM,Jansen ED,Mahadevan-Jansen A,Zhang X,Chen G,Roe AW

    更新日期:2019-04-24 00:00:00

  • Application of hydroxyapatite nanoparticles in tumor-associated bone segmental defect.

    abstract::Hydroxyapatite (HA) has been widely applied in bone repair because of its superior biocompatibility. Recently, a proliferation-suppressive effect of HA nanoparticles (n-HA) against various cancer cells was reported. This study was aimed at assessing the translational value of n-HA both as a bone-regenerating material ...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Zhang K,Zhou Y,Xiao C,Zhao W,Wu H,Tang J,Li Z,Yu S,Li X,Min L,Yu Z,Wang G,Wang L,Zhang K,Yang X,Zhu X,Tu C,Zhang X

    更新日期:2019-08-02 00:00:00

  • Refined symmetry indicators for topological superconductors in all space groups.

    abstract::Topological superconductors are exotic phases of matter featuring robust surface states that could be leveraged for topological quantum computation. A useful guiding principle for the search of topological superconductors is to relate the topological invariants with the behavior of the pairing order parameter on the n...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Ono S,Po HC,Watanabe H

    更新日期:2020-05-01 00:00:00

  • Metal-free activation of molecular oxygen by covalent triazine frameworks for selective aerobic oxidation.

    abstract::Oxygen activation is a critical step in ubiquitous heterogeneous oxidative processes, most prominently in catalysis, electrolysis, and pharmaceutical applications. We present here our findings on metal-free O2 activation on covalent triazine frameworks (CTFs) as an important class of N-rich materials. The O2 activatio...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Abednatanzi S,Gohari Derakhshandeh P,Leus K,Vrielinck H,Callens F,Schmidt J,Savateev A,Van Der Voort P

    更新日期:2020-04-03 00:00:00

  • Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones.

    abstract::G protein-coupled receptors (GPCRs) play a fundamental role in the modulation of synaptic transmission. A pivotal example is provided by the metabotropic glutamate receptor type 4 (mGluR4), which inhibits glutamate release at presynaptic active zones (AZs). However, how GPCRs are organized within AZs to regulate neuro...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Siddig S,Aufmkolk S,Doose S,Jobin ML,Werner C,Sauer M,Calebiro D

    更新日期:2020-04-15 00:00:00

  • Short-lived pause in Central California subsidence after heavy winter precipitation of 2017.

    abstract::The Tulare Basin in Central California is a site of intensive agricultural activity and extraction of groundwater, with pronounced ground subsidence and degradation of water resources over the past century. Spatially extensive observations of ground displacements from satellite-based remote sensing allow us to infer t...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Murray KD,Lohman RB

    更新日期:2018-08-29 00:00:00

  • Hydroclimate footprint of pan-Asian monsoon water isotope during the last deglaciation.

    abstract::Oxygen isotope speleothem records exhibit coherent variability over the pan-Asian summer monsoon (AM) region. The hydroclimatic representation of these oxygen isotope records for the AM, however, has remained poorly understood. Here, combining an isotope-enabled Earth system model in transient experiments with proxy r...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: He C,Liu Z,Otto-Bliesner BL,Brady EC,Zhu C,Tomas R,Clark PU,Zhu J,Jahn A,Gu S,Zhang J,Nusbaumer J,Noone D,Cheng H,Wang Y,Yan M,Bao Y

    更新日期:2021-01-22 00:00:00

  • The structurally disordered paramyxovirus nucleocapsid protein tail domain is a regulator of the mRNA transcription gradient.

    abstract::The paramyxovirus RNA-dependent RNA-polymerase (RdRp) complex loads onto the nucleocapsid protein (N)-encapsidated viral N:RNA genome for RNA synthesis. Binding of the RdRp of measles virus (MeV), a paramyxovirus archetype, is mediated through interaction with a molecular recognition element (MoRE) located near the en...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Cox RM,Krumm SA,Thakkar VD,Sohn M,Plemper RK

    更新日期:2017-02-03 00:00:00

  • Metabolic control of acclimation to nutrient deprivation dependent on polyphosphate synthesis.

    abstract::Polyphosphate, an energy-rich polymer conserved in all kingdoms of life, is integral to many cellular stress responses, including nutrient deprivation, and yet, the mechanisms that underlie its biological roles are not well understood. In this work, we elucidate the physiological function of this polymer in the acclim...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Sanz-Luque E,Saroussi S,Huang W,Akkawi N,Grossman AR

    更新日期:2020-09-30 00:00:00

  • Nonequilibrium evolution of volatility in origination and extinction explains fat-tailed fluctuations in Phanerozoic biodiversity.

    abstract::Fluctuations in biodiversity, large and small, pervade the fossil record, yet we do not understand the processes generating them. Here, we extend theory from nonequilibrium statistical physics to describe the fat-tailed form of fluctuations in Phanerozoic marine invertebrate richness. Using this theory, known as super...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Rominger AJ,Fuentes MA,Marquet PA

    更新日期:2019-06-26 00:00:00

  • Dynamic band structure measurement in the synthetic space.

    abstract::Band structure theory plays an essential role in exploring physics in both solid-state systems and photonics. Here, we demonstrate a direct experimental measurement of the dynamic band structure in a synthetic space including the frequency axis of light, realized in a ring resonator under near-resonant dynamic modulat...

    journal_title:Science advances

    pub_type: 杂志文章


    authors: Li G,Zheng Y,Dutt A,Yu D,Shan Q,Liu S,Yuan L,Fan S,Chen X

    更新日期:2021-01-08 00:00:00