Abstract：
PURPOSE:To compare rod function among diabetic patients without and with mild nonproliferative diabetic retinopathy (DR) and healthy controls by means of scotopic microperimetry and dark-adapted electroretinography. METHODS:Sixty-one diabetic patients and 30 age-matched controls (control group) underwent complete ophthalmic examination, scotopic microperimetry, and dark-adapted 0.01 electroretinography (DA-ERG). RESULTS:In 32 eyes, DR was absent (no-DR group); in 29 eyes, only microaneurysms were observed (DR group). No statistically significant differences in fixation stability, fixation location, or scotopic sensitivity among the 3 groups were observed. Implicit time and amplitude of the DA-ERG b-wave of no-DR and DR groups were not different from controls. Scotopic microperimetry showed a dense scotoma centered onto the fovea in all subjects, consistent with the rod-free zone. Greater scotopic sensitivity was found in a ring located 8° from the fovea (9.33 ± 1.33 dB). CONCLUSIONS:Diabetic patients without DR and with mild nonproliferative DR did not show alterations in rod-based function, as examined by microperimetry and confirmed by DA-ERG. Scotopic microperimetry measures rod-based function and offers additional information in the evaluation of the aspects of involvement of retinal cells in diabetes.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Longhin E,Tormene AP,Olivato E,Convento E,Vujosevic S,Pilotto E,Kotsafti O,Midena Edoi
10.5301/ejo.5000800subject
Has Abstractpub_date
2016-08-04 00:00:00pages
418-24issue
5eissn
1120-6721issn
1724-6016pii
07B39539-122D-45B1-8874-A0288C4302C4journal_volume
26pub_type
杂志文章abstract：PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...
journal_title：European journal of ophthalmology
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abstract：PURPOSE:To report clinical findings and surgical management of 4 patients with congenital nystagmus who presented with a new or reversal of their original horizontal compensatory head posture (CHP) after Anderson-Kestenbaum (A-K) surgery. METHOD:Retrospective chart review. RESULTS:All 4 patients demonstrated a 40°-45...
journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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abstract：:To assess the utility of exfoliative cytology in the diagnosis of chronic conjunctivitis, we compared its findings with microbiological examination and established the correlation between cytology and microbiology in 32 patients with conjunctivitis lasting four weeks or more, with a nonspecific clinical picture. The m...
journal_title：European journal of ophthalmology
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abstract：AIM:A multicentre, randomized, placebo-controlled double-masked study was conducted to assess the efficacy and safety of Rimexolone 1% eye drops in reducing inflammation after cataract surgery and intra-ocular lens implantation. METHODS:Rimexolone 1% (124 patients) or placebo (58 patients) was given, four times a day ...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期：1998-01-01 00:00:00
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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abstract：:We report five cases with a mixture of esotropia and pseudoexotropia due to macular ectopia related cicatricial retinopathy of prematurity (ROP). On inspection, the patients, aged from 9 to 28 years, presented a divergence of the eyes and a nasally decentralised corneal light reflex. The cover test showed esodeviation...
journal_title：European journal of ophthalmology
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doi：
更新日期：1996-10-01 00:00:00
abstract：PURPOSE:To describe a clinical case of corneoscleral xanthogranuloma, a rare manifestation of juvenile xanthogranuloma, and xanthoma disseminatum, which responded well to chemotherapy. METHODS:Interventional case report and literature search. RESULTS:A 9-year-old female patient with a disseminated disease showed comp...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119832187
更新日期：2020-03-01 00:00:00
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journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2004-11-01 00:00:00
abstract：PURPOSE:To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China. METHODS:The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao Un...
journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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pub_type： 杂志文章,随机对照试验
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journal_title：European journal of ophthalmology
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