Abstract:
PURPOSE:To assess the difference in best-corrected visual acuity (BCVA) at presentation between the first and second eye in patients with bilateral neovascular age-related macular degeneration (AMD). METHODS:We reviewed the charts of all patients who had a clinical examination for neovascular AMD at the University Eye Clinic of Creteil in January 2013. We retrospectively analyzed demographic and clinical data for 264 patients. RESULTS:In the fellow eye, choroidal neovascularization (CNV) developed in 75/264 patients (28.4%) with a time interval between the 2 events of 30.3 months (range 6-145). Data were available on 65 patients: 14/65 (21.5%) were asymptomatic, 24/65 (36.9%) had BCVA >20/40, whereas at the time of CNV diagnosis in the first eye, no patient was asymptomatic (p<0.0001), and 11/65 (16.9%) eyes had BCVA >20/40 (p<0.0001). The mean BCVA of the first affected eye was 0.68 (± 0.41) logarithm of minimum angle of resolution (logMAR) and the mean BCVA for the second eye was 0.36 (± 0.29) logMAR (p<0.0001). CONCLUSIONS:The BCVA at the time of diagnosis of CNV was higher in the second eye than in the first affected eye. This was possibly due to several factors including systematic bilateral examination in follow-up of unilateral exudative AMD that allowed detection of 20% of cases.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Chevreaud O,Semoun O,Blanco-Garavito R,Kamami-Levy C,Merle B,Jung C,Querques G,Souied EHdoi
10.5301/ejo.5000649subject
Has Abstractpub_date
2016-01-01 00:00:00pages
44-7issue
1eissn
1120-6721issn
1724-6016pii
40620300-9BDC-4F07-988D-AAA1E58DDB18journal_volume
26pub_type
杂志文章abstract:PURPOSE:To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods. METHODS:Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21, an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100105
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800415
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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更新日期:2013-11-01 00:00:00
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1998-01-01 00:00:00
abstract::Age-related macular degeneration is a condition (a) characterized by accumulation of membranous debris on both sides of the retinal pigment epithelium (RPE) basement membrane. Clinical manifestations of drusen, atrophy of the RPE/choriocapillaris, RPE detachment, and choroidal new vessel (CNV) formation occur after ag...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4076
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To review and analyze the epidemiological profile, clinical characteristics and visual outcomes in patients attended for traumatic open globe injury (OGI) at our hospital over a 5-year period. DESIGN:Retrospective chart review study. METHODS:Retrospective analysis of all patients attended at Fundación Jiménez...
journal_title:European journal of ophthalmology
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abstract:PURPOSE:We present the clinical, pathologic, and genetic findings of the first reported case of choroidal melanoma that developed a late recurrence and aggressive metastasis to the skull base without evidence of hepatic involvement. METHODS:Retrospective chart review and clinicopathologic correlation of ocular and bra...
journal_title:European journal of ophthalmology
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doi:10.5301/ejo.5000468
更新日期:2014-09-01 00:00:00
abstract::Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF tech...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract:PURPOSE:To investigate the ocular and orbital complications observed in children treated for retinoblastoma. SUBJECTS AND METHODS:We retrospectively studied 73 children (39 boys, 34 girls) suffering from retinoblastoma. Thirty-six had bilateral tumor and 37 unilateral disease for a total of 109 eyes affected. The foll...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract:PURPOSE:To look for ophthalmologic abnormalities in 15 patients with Wolfram syndrome, also known as DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness). METHODS:Fifteen patients from four inbred families diagnosed as having Wolfram syndrome at the National Center for Diabetes, Endocri...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2002-03-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
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更新日期:2004-09-01 00:00:00
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journal_title:European journal of ophthalmology
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doi:10.1177/112067210001000203
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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