The effects of Rimexolone 1% in postoperative inflammation after cataract extraction. A double-masked placebo-controlled study.

Abstract:

AIM:A multicentre, randomized, placebo-controlled double-masked study was conducted to assess the efficacy and safety of Rimexolone 1% eye drops in reducing inflammation after cataract surgery and intra-ocular lens implantation. METHODS:Rimexolone 1% (124 patients) or placebo (58 patients) was given, four times a day for 14 days starting 22-34 hours after surgery. All patients also received tobramycin 0.3% four times a day for 7 days. The clinical signs of ocular inflammation were recorded on days 1, 3, 8, 15 and 17 or 18. RESULTS:Rimexolone 1% markedly decreased the mean inflammation severity scores, and the sum of clinical assessments of cells and flare in the anterior chamber compared with placebo at each assessment. In addition, the percentage of patients with no anterior chamber inflammation was significantly higher with Rimexolone 1% than with the placebo at each assessment. All these results were statistically significant. Intra-ocular pressure did not rise after treatment with Rimexolone 1%. CONCLUSIONS:The results suggest that Rimexolone 1% ophthalmic solution is an effective and safe steroidal anti-inflammatory agent for topical use following cataract surgery and intra-ocular lens implantation.

journal_name

Eur J Ophthalmol

authors

Bron A,Denis P,Hoang-Xuan TC,Boureau-Andrieux C,Crozafon P,Hachet E,Medhorn E,Akingbehin A

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

16-21

issue

1

eissn

1120-6721

issn

1724-6016

journal_volume

8

pub_type

临床试验,杂志文章,多中心研究,随机对照试验
  • The predictive value of magnetic resonance imaging of retinoblastoma for the likelihood of high-risk pathologic features.

    abstract:PURPOSE::To evaluate the predictive value of magnetic resonance imaging in retinoblastoma for the likelihood of high-risk pathologic features. METHODS::A retrospective study of 64 eyes enucleated from 60 retinoblastoma patients. Contrast-enhanced magnetic resonance imaging was performed before enucleation. Main outcom...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118781200

    authors: Hiasat JG,Saleh A,Al-Hussaini M,Al Nawaiseh I,Mehyar M,Qandeel M,Mohammad M,Deebajah R,Sultan I,Jaradat I,Mansour A,Yousef YA

    更新日期:2019-03-01 00:00:00

  • Testing the reliability of an eye-dedicated triaging system: the RESCUE.

    abstract:PURPOSE:To calculate the reliability of an eye-dedicated triaging system named Rome Eye Scoring System for Urgency and Emergency (RESCUE). METHODS:There were four coding parameters: pain, redness, loss of vision, and risk of open globe. Each parameter is assigned a score, the sum of which allows color coding. There we...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800321

    authors: Rossi T,Boccassini B,Cedrone C,Iossa M,Mutolo MG,Lesnoni G,Mutolo PA

    更新日期:2008-05-01 00:00:00

  • Nonmydriatic fundus camera for diabetic retinopathy screening in a safety net hospital: effectiveness, prevalence, and risk factors.

    abstract:PURPOSE:To evaluate diabetic retinopathy (DR) prevalence and risk factors, and the effectiveness of nonmydriatic fundus camera as a screening tool for the detection of DR, in a safety net hospital. METHODS:This was a retrospective, population-based, cross-sectional study. Diabetic patients, referred by their primary c...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000515

    authors: Schwartz S,Harasawa M,Baldivieso V,Sabel AL,Mandava N,Quiroz-Mercado H

    更新日期:2015-03-01 00:00:00

  • Antioxidant status modifications by topical administration of dorzolamide in primary open-angle glaucoma.

    abstract:PURPOSE:This study deals with the role of the topical administration of dorzolamide eyedrops on the oxidative/antioxidant status of aqueous humor in patients with primary open angle glaucoma (POAG). METHODS:A case-control study including 130 patients distributed into three groups was carried out: 1) patients with POAG...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210901900408

    authors: Zanon-Moreno V,Garcia-Medina JJ,Gallego-Pinazo R,Vinuesa-Silva I,Moreno-Nadal MA,Pinazo-Duran MD

    更新日期:2009-07-01 00:00:00

  • Identification of separated lenticular planes using optical coherence tomography.

    abstract:PURPOSE:To discuss how optical coherence tomography can be used to identify separated lenticular planes during small incision lenticule extraction (SMILE). METHODS:SMILE procedures were performed on 26 eyes of 13 patients. An anterior segment optical coherence tomography examination was performed after laser scan. Ant...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119853207

    authors: Zheng K,Han T,Zhao F,Han Y,Zhou X

    更新日期:2020-09-01 00:00:00

  • Anatomic and visual outcomes of 23-G vitrectomy without scleral buckling for primary rhegmatogenous retinal detachment.

    abstract:PURPOSE:To evaluate the anatomic success rate, visual acuity (VA) changes, and complications of 23-G vitrectomy without associated scleral procedures for the treatment of primary rhegmatogenous retinal detachment (PRRD). 
 METHODS:Patients diagnosed with PRRD were considered for inclusion. Patients with evidence of pr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000234

    authors: Figueroa MS,Contreras I,Noval S,PACORES Study Group.

    更新日期:2013-05-01 00:00:00

  • Sealed implantation of foldable intraocular lenses.

    abstract:PURPOSE:To evaluate the safety and efficacy of sealed implantation, a simple technique for implanting foldable intraocular lenses (IOLs). METHODS:This was a retrospective study including consecutive patients who underwent phacoemulsification cataract using the sealed implantation technique. Sealed implantation is a te...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000997

    authors: Nath D,Blumenthal EZ,Sharma M,Mimouni M

    更新日期:2017-08-30 00:00:00

  • Secondary or new compensatory head posture after Anderson-Kestenbaum surgery.

    abstract:PURPOSE:To report clinical findings and surgical management of 4 patients with congenital nystagmus who presented with a new or reversal of their original horizontal compensatory head posture (CHP) after Anderson-Kestenbaum (A-K) surgery. METHOD:Retrospective chart review. RESULTS:All 4 patients demonstrated a 40°-45...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.8356

    authors: Ugurbas SC,Baker JD

    更新日期:2012-03-01 00:00:00

  • Surgical repair of large cyclodialysis clefts.

    abstract:PURPOSE:To describe a new surgical technique to effectively close large (>180 degrees) cyclodialysis clefts. METHODS:Our method involves the use of procedures commonly associated with repair of retinal detachment and complex cataract extraction: phacoemulsification with placement of a capsular tension ring followed by...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000868

    authors: Gross JB,Davis GH,Bell NP,Feldman RM,Blieden LS

    更新日期:2017-05-11 00:00:00

  • Prevalence of self-reported computer vision syndrome symptoms and its associated factors among university students.

    abstract:PURPOSE:To determine the prevalence of symptoms of computer vision syndrome and to identify its associated factors. The secondary objective was to assess knowledge and practices related to preventing computer vision syndrome symptoms. METHODS:The data for this cross-sectional study were collected through a self-admini...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118815110

    authors: Al Tawil L,Aldokhayel S,Zeitouni L,Qadoumi T,Hussein S,Ahamed SS

    更新日期:2020-01-01 00:00:00

  • Copper intraocular foreign body: diagnosis and treatment.

    abstract::Copper intraocular foreign bodies (IOFB) are relatively common after penetrating eye injuries. Ocular signs and symptoms vary greatly in relation to the copper content, ranging from chronic uveitis and severe visual loss for IOFB containing more than 85% copper, to local copper deposits with no severe ocular damage fo...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Billi B,Lesnoni G,Scassa C,Giuliano MA,Coppè AM,Rossi T

    更新日期:1995-10-01 00:00:00

  • Systemic evaluation of patients with central serous chorioretinopathy: A case-control study.

    abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120975698

    authors: Kumawat D,Ravi AK,Sahay P,Alam T,Desai A,Kumar A

    更新日期:2020-11-25 00:00:00

  • Phakic intraocular lenses after scleral buckling for retinal detachment.

    abstract:PURPOSE:To assess efficacy and safety of angle-supported phakic intraocular lenses (PIOL) implanted after scleral buckling for retinal detachment. SETTING:Private practice in Siena, Italy. METHODS:Retrospective, noncomparative consecutive case series. Inclusion criteria for retrospective evaluation were previous unco...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210701700319

    authors: Leccisotti A

    更新日期:2007-05-01 00:00:00

  • Late endoscopic evaluation of the ostium size after external dacryocystorhinostomy.

    abstract:OBJECTIVE:To evaluate the effect of chronicity on the size of the ostium after external dacryocystorhinostomy (DCR) with intubation. METHODS:Design: A retrospective chart review of patients who underwent external DCR with intubation over 10 years from January 2003 at a tertiary hospital. All patients were recruited an...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120976044

    authors: Al Huthail RR,Al-Faky YH

    更新日期:2020-11-24 00:00:00

  • Morbidity of malignant tumours with ocular location in the Bulgarian district of Plovdiv.

    abstract:PURPOSE:To study the actual and standardized morbidity of malignant tumours with ocular location (per 100,000 inhabitants) over a period of ten years. METHODS:Retrospective evaluation of the registers of the Plovdiv District Oncology Centre and the Department of Ophthalmology in the Medical University. It includes 698...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Atanassova-Chilova BK

    更新日期:1996-04-01 00:00:00

  • Diabetes mellitus: a risk factor affecting visual outcome in branch retinal vein occlusion.

    abstract:PURPOSE:The prognosis of visual acuity (VA) after branch retinal vein occlusion (BRVO) in patients with diabetes mellitus is unknown compared to the VA in non-diabetic patients with BRVO. The aim of this study was to evaluate the visual outcome of BRVO in diabetic and non-diabetic patients. METHODS:A retrospective cas...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/112067210301300709

    authors: Swart J,Reichert-Thoen JW,Suttorp-Schulten MS,van Rens GH,Polak BC

    更新日期:2003-08-01 00:00:00

  • Switching intravitreal anti-VEGF treatment in neovascular age-related macular degeneration.

    abstract:PURPOSE:To compare the outcomes after switching between bevacizumab and ranibizumab therapy due to poor treatment effect in neovascular age-related macular degeneration (AMD). METHODS:This is a retrospective review of patients with neovascular AMD with first treatment using intravitreal bevacizumab (group 1) or ranibi...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000480

    authors: Küçükerdönmez C,Gelisken F,Yoeruek E,Bartz-Schmidt KU,Leitritz MA

    更新日期:2015-01-01 00:00:00

  • Effect of interferon α2a in cystoid macular edema due to intraocular infection.

    abstract:PURPOSE:Cystoid macular edema (CME) is a severe complication and a major cause of visual loss in patients with intraocular infection. In this type of CME, therapeutic strategies remain controversial. We aimed to investigate the efficacy and tolerability of interferon (IFN)-α2a in cystoid macular edema caused by intraoc...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000591

    authors: Qian Z,Fardeau C,Cardoso JN,Jellab B,Fan X,LeHoang P

    更新日期:2015-09-01 00:00:00

  • Aggressive skull base metastasis from uveal melanoma: a clinicopathologic study.

    abstract:PURPOSE:We present the clinical, pathologic, and genetic findings of the first reported case of choroidal melanoma that developed a late recurrence and aggressive metastasis to the skull base without evidence of hepatic involvement. METHODS:Retrospective chart review and clinicopathologic correlation of ocular and bra...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000468

    authors: Yonekawa Y,Kim IK,Gragoudas ES,Njauw CN,Tsao H,Jakobiec FA,Stacy RC

    更新日期:2014-09-01 00:00:00

  • Decreased ocular pulse amplitude associated with functional and structural damage in open-angle glaucoma.

    abstract:PURPOSE:To assess the relationship of ocular pulse amplitude (OPA), as measured by dynamic contour tonometry (DCT), with structural and functional damage in patients with open-angle glaucoma (OAG). METHODS:In this cross-sectional, observational study, 242 eyes of 139 patients with OAG underwent Goldmann applanation to...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000043

    authors: Kynigopoulos M,Tzamalis A,Ntampos K,Schlote T

    更新日期:2012-01-01 00:00:00

  • Silicone oil-induced displacement of subretinal hemorrhage in age-related macular degeneration.

    abstract:PURPOSE:To describe the use of silicone oil (SO) in combination with subretinal recombinant tissue plasminogen activator (rtPA) to achieve dislocation of large subretinal hemorrhage secondary to exudative age-related macular degeneration (AMD). METHODS:A single-eye 81-year-old woman, known for exudative AMD, presented...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120952349

    authors: Corbelli E,Iuliano L,Fogliato G,Bandello F,Codenotti M

    更新日期:2020-08-18 00:00:00

  • Traumatic hyphema in a patient with severe hemophilia A: Clinical features and management.

    abstract:PURPOSE:To describe a case of traumatic hyphema in a patient with severe hemophilia A. CASE:We present a case of a 16-year-old boy with severe hemophilia A who presented to our ophthalmology department with total hyphema and elevated intraocular pressure 3 days after a history of blunt ocular trauma on his right eye. ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119856515

    authors: Belviranli S,Ozkagnici A,Tokgoz H,Bitirgen G,Caliskan U

    更新日期:2019-06-12 00:00:00

  • Tumor-related lipid exudation and associated tumor-related complications after plaque radiotherapy of posterior uveal melanoma.

    abstract:OBJECTIVE:To identify complications associated with tumor-related lipid exudation (TRLE) after plaque radiotherapy of posterior uveal melanoma.
 METHODS:Comparative study including 294 patients with posterior uveal melanoma who developed TRLE after plaque radiotherapy (TRLE group) and 294 patients who did not develop ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000236

    authors: Mashayekhi A,Tuncer S,Shields CL,Shields JA

    更新日期:2013-05-01 00:00:00

  • Suppression of Covid-19 outbreak among healthcare workers at the Treviso Regional Hospital, Italy and lessons for ophthalmologists.

    abstract:PURPOSE:To describe a strategy to reduce Covid-19 spread among healthcare workers and provide ophthalmologists with recommendations useful for a possible second wave of Covid-19 in Autumn. METHODS:Epidemiological surveillance at the Cà Foncello Hospital (Veneto, Italy) since 24 February 2020 to 24 April 2020 when the ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120982520

    authors: Grosso A,Rigoli R,Formentini S,Di Perri G,Scotton P,Dapavo G,Fioretto M,Scarpa G

    更新日期:2020-12-15 00:00:00

  • Incidence and quantitative analysis of dissociated optic nerve fiber layer appearance: real loss of retinal nerve fiber layer?

    abstract:PURPOSE:To assess the association between appearance of dissociated optic nerve fiber layer (DONFL) after internal limiting membrane (ILM) peeling and changes in the macular nerve fiber layer (NFL) area by spectral-domain optical coherence tomography (SD-OCT). METHODS:This study included 132 consecutive patients who h...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5001067

    authors: Kim YJ,Lee KS,Joe SG,Kim JG

    更新日期:2018-05-01 00:00:00

  • Redeployment of ophthalmologists in the United Kingdom during the Coronavirus Disease Pandemic.

    abstract:BACKGROUND:During the current coronavirus (COVID-19) pandemic, some ophthalmologists across the United Kingdom (UK) have been redeployed to areas of need across the National Health Service (NHS). This survey was performed to assess aspects of this process including training & education, tasks expected, availability of ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120953339

    authors: Lim C,De Silva I,Moussa G,Islam T,Osman L,Malick H,Deol S,Youssef M,Farrag A,Ashraf R,Burgula S,Thompson J

    更新日期:2020-08-27 00:00:00

  • Ultrasound biomicroscopy and OCT findings in posterior microphthalmos.

    abstract:PURPOSE:Posterior microphthalmos is a rare ocular abnormality. The authors report two siblings with bilateral posterior microphthalmos. METHODS:Two siblings (aged 10 and 13) were admitted with a history of low degree of vision. Ophthalmologic examinations, ocular ultrasonography, ultrasonic biomicroscopy (UBM), and op...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800331

    authors: Erdol H,Kola M,Turk A,Akyol N

    更新日期:2008-05-01 00:00:00

  • Congenital cataract extraction with primary aphakia and secondary intraocular lens implantation in the posterior chamber.

    abstract:PURPOSE:To evaluate visual outcomes, eye movement abnormalities, and postoperative complications after secondary posterior chamber intraocular lens (IOL) implantation in aphakic children who had initial LAC correction. METHODS:A retrospective study was carried out on 53 patients (94 eyes). Following aphakic surgery an...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800608

    authors: Magli A,Fimiani F,Bruzzese D,Carelli R,Giani U,Iovine A

    更新日期:2008-11-01 00:00:00

  • Long-term follow-up of a case of posterior microphthalmos (PRSS56) with hyperautofluorescent retinal pigment epithelial deposits.

    abstract:PURPOSE:To report a case of posterior microphthalomos (PM) related to PRSS56 gene mutation with long term follow up with multimodal imaging findings. METHODS:Single retrospective case report. RESULTS:A 43-year old male patient presented in 2009 with bilateral reduced vision. Clinical examination and multimodal imagin...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120949756

    authors: Sen P,Robson AG,Webster AR,Nicholson L,Sivaprasad S,Hykin PG

    更新日期:2020-08-17 00:00:00

  • Tear film parameters before and after intracorneal ring segment implantation in keratoconic eyes.

    abstract:PURPOSE:To assess signs of dry eye syndrome in keratoconic eyes following intracorneal ring segment (ICRS) implantation. PATIENT AND METHODS:Twenty eyes of 20 consecutive patients with keratoconus were assessed for tear film changes following ICRS implantation at 6 months postoperatively. Evaluated parameters included...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120958301

    authors: Vastardis I,Gatzioufas Z,McLintock C,Kohlhaas M,Hamada S,Lake D,Elalfy M

    更新日期:2020-09-21 00:00:00