Abstract:
PURPOSE:Cystoid macular edema (CME) is a severe complication and a major cause of visual loss in patients with intraocular infection. In this type of CME, therapeutic strategies remain controversial. We aimed to investigate the efficacy and tolerability of interferon (IFN)-α2a in cystoid macular edema caused by intraocular infection. METHODS:In this retrospective, noncomparative, interventional case series, 5 patients (6 eyes) who were diagnosed with intraocular infection with chronic CME were included. Interferon-α2a (3 million units 3 times a week) was administered subcutaneously. Clinical observations were recorded before and after treatment. RESULTS:The average duration of CME before treatment with IFN-α was 26 months. According to the preset criteria, IFN-α2a therapy was shown to be effective in 2 patients (3 eyes), effective dose-dependent in 2 patients, and partly effective in 1 patient, and was well-tolerated in 4 patients. The most common side effect was flu-like symptoms. CONCLUSIONS:Interferon α-2a may be an effective alternative treatment for CME due to intraocular infection that is resistant to other treatment. Studies with larger sample sizes are required to confirm this conclusion.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Qian Z,Fardeau C,Cardoso JN,Jellab B,Fan X,LeHoang Pdoi
10.5301/ejo.5000591subject
Has Abstractpub_date
2015-09-01 00:00:00pages
431-6issue
5eissn
1120-6721issn
1724-6016pii
4B63CD6B-2F25-4E50-AE11-60D946F7F59Djournal_volume
25pub_type
杂志文章abstract:PURPOSE:To report management of diplopia with botulinum toxin injection in traumatic multiple ocular motor cranial neuropathies. METHODS:Alternate prism and cover measurement of deviation in different positions of gaze, examination of ductions, field of binocular single vision, and complete ocular anterior and poste...
journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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更新日期:2013-07-01 00:00:00
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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更新日期:2006-11-01 00:00:00
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更新日期:2005-07-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2011-09-01 00:00:00
abstract:AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...
journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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更新日期:2014-05-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2008-03-01 00:00:00
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更新日期:2014-07-01 00:00:00
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更新日期:2020-05-31 00:00:00
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更新日期:2011-09-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2009-09-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2007-07-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2013-05-01 00:00:00
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更新日期:2020-08-10 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2002-01-01 00:00:00
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更新日期:2007-11-01 00:00:00