Abstract：
PURPOSE:To describe the unusual complication of retinal pigment epithelial (RPE) tear after intravitreal ranibizumab (Lucentis) for subfoveal fibrovascular pigment epithelial detachment (PED) and its effective management. METHODS:Chart review for case report of RPE tear after ranibizumab. RESULTS:An inferior RPE tear was documented by fluorescein angiography, fundus photography, and optical coherence tomography (OCT) 1 month after receiving repeat ranibizumab injection in the right eye of a patient with bilateral subfoveal fibrovascular PED. He had undergone multiple bevacizumab followed by ranibizumab injections for neovascular age-related macular degeneration (AMD) in both eyes, starting 6 months previously. Subsequent antivascular endothelial growth factor (VEGF) therapy improved vision of right eye from 20/200 to 20/40, despite RPE tear. CONCLUSIONS:RPE tear may form after anti-VEGF therapy, including ranibizumab injection. Further anti-VEGF therapy may preserve or improve vision. To the authors' knowledge, this is first case report of effective suppression of neovascular activity with bevacizumab after an RPE tear following ranibizumab therapy.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Chan CK,Lin SGdoi
10.1177/112067210701700432subject
Has Abstractpub_date
2007-07-01 00:00:00pages
674-6issue
4eissn
1120-6721issn
1724-6016journal_volume
17pub_type
杂志文章abstract：PURPOSE:To evaluate the efficacy of 3 different surgical techniques for convergence excess esotropia: augmented medial rectus recession, medial rectus recession plus Faden, and slanted medial rectus recession. METHODS:Twenty-nine patients with convergence excess esotropia were divided into 3 groups. Group A included 9...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.2010.5225
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:To determine the incidence, timing and risk factors for glaucoma and visual axis opacification development following surgery for congenital cataract in the first year of life. METHODS:A prospective case series of all cataract surgery performed in Temple Street Children's University Hospital over a 28-year peri...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119862878
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:We report spectral domain optical coherence tomography findings of the peripheral retina in a patient with senile (acquired) retinoschisis. METHODS:This is an observational case report. Spectral domain optical coherence tomography was performed to image the peripheral retina at the area of retinoschisis in a 7...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000610
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:To evaluate the diagnostic ability of a new perimetric procedure in glaucoma. METHODS:Pulsar perimeter shows white circular sinusoidal grating patterns with decreasing amplitude, 5 in diameter, 500 msec in duration in 66 locations. The stimuli scale combines spatial resolution and contrast. The stimuli were sh...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.2727
更新日期：2004-01-01 00:00:00
abstract：PURPOSE:To compare the symptoms, signs, and results of objective tests for dry eye syndrome (DES) in type 1 diabetes mellitus (T1DM) patients and controls. METHODS:A total of 104 children with T1DM and 104 age- and sex-matched controls were compared in terms of the symptoms, signs, and results of objective tests for D...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700601
更新日期：2007-11-01 00:00:00
abstract：PURPOSE:To evaluate diabetic retinopathy (DR) prevalence and risk factors, and the effectiveness of nonmydriatic fundus camera as a screening tool for the detection of DR, in a safety net hospital. METHODS:This was a retrospective, population-based, cross-sectional study. Diabetic patients, referred by their primary c...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000515
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:The purpose of this study was to assess indications and outcome of carotid Doppler ultrasound requested by ophthalmologists from an eye hospital over a period of three years. METHODS:This retrospective study was designed to analyse data for all patients referred to have carotid Doppler ultrasound from 1999 to ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of fixed-combination brimonidine tartrate 0.2%/timolol 0.5% ophthalmic solution dosed BID and demonstrate non-inferiority to concomitant use of brimonidine tartrate 0.2% BID and timolol 0.5% BID in glaucoma and ocular hypertension patients with intraocular pressure (IOP) unco...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.4076
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To investigate the mean values of intraocular pressure (IOP) measured with noncontact tonometer (NCT) and evaluate the factors that may affect IOP. METHODS:A total of 850 subjects who were admitted to our clinic between March 2005 and February 2006 were recruited for the study. Subjects having blepharitis, con...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210901900109
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:To compare diagnostic capabilities and agreement between Oculus-Spark perimetry and 3 procedures of glaucoma morphologic analysis. METHODS:A total of 102 normal eyes and 104 consecutive eyes with suspected or confirmed glaucoma (1 eye per subject) were analyzed in a prospective observational case-control study...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000233
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:Preoperative and postoperative optical coherence tomography (OCT) of macular pathologies can be regarded as the gold standard diagnostic technique, providing detailed information on the microstructures of the macula for planning the surgical procedure and comparing improvements after surgery in the follow-up pe...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5001058
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:To evaluate the anatomic success rate, visual acuity (VA) changes, and complications of 23-G vitrectomy without associated scleral procedures for the treatment of primary rhegmatogenous retinal detachment (PRRD). METHODS:Patients diagnosed with PRRD were considered for inclusion. Patients with evidence of pr...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000234
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:To describe and compare long-term (> or = 36 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by Beta-RT or by sham irradiation. METHODS:Prospective, multicenter, randomized, double-blind study. After BSE of their pterygium, patients were randomized to ei...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1177/112067210801800301
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To report a real-life experience with the Argus II retinal prosthesis system in blind patients with end-stage retinitis pigmentosa (RP) or choroideremia (CHM), focusing on the pivotal role of optical coherence tomography (OCT) in both preoperative and postoperative management. METHODS:This hospital-based case ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000852
更新日期：2017-01-19 00:00:00
abstract：:We sent questionnaires to 424 retina specialists in order to compile information on the use of fluorescein angiography in pregnant women. Four-hundred and three specialists responded. Of these, 313 (78%) had never performed fluorescein angiography on a pregnant woman. Ninety specialists (22%) had performed at least on...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVE:To identify complications associated with tumor-related lipid exudation (TRLE) after plaque radiotherapy of posterior uveal melanoma. METHODS:Comparative study including 294 patients with posterior uveal melanoma who developed TRLE after plaque radiotherapy (TRLE group) and 294 patients who did not develop ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000236
更新日期：2013-05-01 00:00:00
abstract：:We report five cases with a mixture of esotropia and pseudoexotropia due to macular ectopia related cicatricial retinopathy of prematurity (ROP). On inspection, the patients, aged from 9 to 28 years, presented a divergence of the eyes and a nasally decentralised corneal light reflex. The cover test showed esodeviation...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：PURPOSE:Iridoschisis is a rare, bilateral condition, found in the elderly and connected with the coexistence of closed-angle glaucoma. Stromal atrophy or separation of the anterior from the posterior laminae with coexisting posterior synechiae are present. Phacoemulsification in eyes with a narrow pupil, unresponsive t...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000300
更新日期：2013-11-01 00:00:00
abstract：PURPOSE:Vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) are angiogenic mediators that share a significant proinflammatory activity. Both substances have been suggested to play a key role in uveitis pathogenesis. The authors analyzed VEGF and IL-8 levels in the aqueous humor and serum of patients with...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700611
更新日期：2007-11-01 00:00:00
abstract：:Abstracts from the 25th Meeting of the European Association for the Study of Diabetes Eye Complications Study Group (EASDec). Turin, Italy - June 26-28, 2015. ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000612
更新日期：2015-04-22 00:00:00
abstract：:In renal failure the incidence of pingueculae is significantly higher than in a comparable control group but there is no evidence that the calcific precipitation in renal failure is of a dystrophic nature. The lime salts are not located within the area of elastotic degeneration, a prerequisite for dystrophic degenerat...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of inferior sutureless sclerotomies without subretinal fluid drainage for the treatment of bullous exudative retinal detachment secondary to diffuse retinal pigment epitheliopathy. METHODS:A retrospective interventional case series of eyes treated with two inferior postequatorial full-...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210801800618
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:To study the morphologic characteristics of the optic nerve (ON) by using an experimental model of knockout mice for the expression of the PTEN gene, mainly involved in cell cycle arrest, apoptosis control, and cell size regulation. METHODS:The eyeballs with the retrobulbar ON attached were obtained from 26-we...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.4510
更新日期：2006-05-01 00:00:00
abstract：:Although it is now possible to significantly reduce the incidence of blindness secondary to diabetes mellitus, large numbers of diabetic patients still experience visual loss due to retinal complications of the disease. This implies that protocols for the diagnosis and treatment of diabetic retinopathy used in the var...
journal_title：European journal of ophthalmology
pub_type： 社论
doi：10.1177/112067219900900302
更新日期：1999-07-01 00:00:00
abstract：PURPOSE:To study the actual and standardized morbidity of malignant tumours with ocular location (per 100,000 inhabitants) over a period of ten years. METHODS:Retrospective evaluation of the registers of the Plovdiv District Oncology Centre and the Department of Ophthalmology in the Medical University. It includes 698...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：PURPOSE:To evaluate the effect of intracameral Bevacizumab on trabeculectomy success rates. METHODS:A prospective, randomized, interventional clinical trial. Patients with primary open-angle glaucoma were randomly assigned to two groups: trabeculectomy with mitomycin C and trabeculectomy with mitomycin C and intracame...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1177/1120672119874682
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:Norrie disease (ND) is a rare X-linked recessive disorder characterized by congenital blindness, which is often associated with sensorineural hearing loss and mental retardation. X-linked familial exudative vitreoretinopathy (FEVR) is a hereditary disorder characterized by an abnormality of the peripheral retin...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067219900900312
更新日期：1999-07-01 00:00:00
abstract：PURPOSE:To compare retinal nerve fiber layer thickness (RNFLT) and inner macula thickness changes measured with Fourier-domain optical coherence tomography (FD-OCT) and scanning laser polarimetry during the course of acute optic neuritis (ON). METHODS:Nine eyes of 7 consecutive patients with multiple sclerosis (MS) we...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2010.5844
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:To evaluate the usefulness of non-mydriatic fundus camera (NMFu-camera) and frequency doubling perimeter (FDP) for detecting glaucoma in a general population. METHODS:This prospective observational multicenter study consisted in screening for glaucoma in the populations of three Belgian cities. Intraocular pre...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1177/112067210401400505
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:Evaluate the long term outcomes of myopic-LASIK in a late adolescent population (age ⩾17 and <20 at the time of surgery). METHODS:Monocentric retrospective case series study. Eyes with at least 3 years of follow-up time were included. Primary outcome measures were long term efficacy, safety and stability of th...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120969039
更新日期：2020-10-30 00:00:00
