Abstract：
PURPOSE:To analyze results of amniotic membrane transplantation (AMT) in treatment of corneal ulceration after severe chemical and thermal injuries. METHODS:Analysis of 55 AMT in 53 patients (53 eyes) with corneal ulceration and limbal deficiency 180-360° of the limbus after grade 4-6 (Dua classification, 2001) chemical and thermal injuries was performed. Mean terms of the operation were 46.1 ± 46.4 days after the injury (range 8-181 days). Preoperative visual acuity (VA) was <0.01 in 33/53 patients (62.3%). Mean follow-up period was 8.8 ± 10.1 months (range 1.5-46 months). RESULTS:Further corneal ulceration was prevented in 54/55 cases (98.1%), cornea epithelialized after 42/55 AMT (76.3%). Mean terms of corneal epithelialization were 24.2 ± 26.7 days after AMT (range 6-123 days). Corneal defect recurred in 3/42 successful cases (7.1%). Limbal deficiency of different extent with subsequent corneal conjunctivalization developed in all successful patients. The VA was ≥0.01 (range 0.01-1.0) in 23/42 patients (54.8%) with corneal epithelialization. The VA at the last visit was improved on 2 and more lines on the eye chart compared to preoperative VA in 15/42 patients with corneal epithelialization (35.7%), did not change in 18/42 successful patients (42.9%), and decreased on one line in 9/42 of these patients (26.2%). Symblepharon developed in 23/42 successful patients (54.7%). CONCLUSIONS:Amniotic membrane transplantation may stop ulceration and promote corneal epithelialization in the majority of patients with the most severe chemical or thermal eye injuries in case of timely application of the operation and adequate fixation of the AMT graft.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Iakimenko SA,Buznyk OI,Rymgayllo-Jankowska Bdoi
10.5301/ejo.5000243subject
Has Abstractpub_date
2013-07-01 00:00:00pages
496-503issue
4eissn
1120-6721issn
1724-6016pii
49E6FACE-9107-4728-AB30-1B5C8C22C936journal_volume
23pub_type
杂志文章abstract：PURPOSE:To report a case of monolateral preretinal fibrovascularproliferations in a young adult woman, who had suffered from incontinentia pigmenti (IP) during her first month of life. METHODS:Case report. RESULTS:Circumscribed preretinal fibrovascular proliferations, adjacent to a mid-peripheral area of snail track ...
journal_title：European journal of ophthalmology
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abstract：OBJECTIVE:To assess the role of 10-2 visual field (VF) test in different stages of glaucoma. METHODS:In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. We com...
journal_title：European journal of ophthalmology
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abstract：:Copper intraocular foreign bodies (IOFB) are relatively common after penetrating eye injuries. Ocular signs and symptoms vary greatly in relation to the copper content, ranging from chronic uveitis and severe visual loss for IOFB containing more than 85% copper, to local copper deposits with no severe ocular damage fo...
journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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doi：
更新日期：1993-04-01 00:00:00
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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更新日期：2020-11-02 00:00:00
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journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210501500109
更新日期：2005-01-01 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2002-03-01 00:00:00
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