Abstract:
PURPOSE:The effect of elevated blood glucose level on the myogenic response of human retinal arterioles to acute increases in blood pressure is investigated. METHODS:The vascular response to raised blood pressure (Bayliss effect) was measured in 12 healthy volunteers by use of the retinal vessel analyzer (RVA). For a 9-minute period an on-line measurement of the diameter of a retinal branch arteriole was performed. After the first 3 minutes (baseline measurement) a second phase with 3 minutes of isometric exercise caused an acute rise in blood pressure, followed by 3 minutes of recovery (phase III). After the first session 100 g glucose were administered per os. After 30 minutes blood glucose was measured again and an identical second session was performed with higher blood glucose levels. The Wilcoxon test was used for statistical analysis. RESULTS:During the first session a rise in mean arterial pressure of 22.8 (+/-8.4) mmHg was followed by an arterial vasoconstriction of -6.6 (+/-1.7) %. The administration of 100 g glucose resulted in a significant rise in blood glucose levels within 30 minutes between the two sessions (4.35 mmol/L vs 7.46 mmol/L) (p=0.002). The blood pressure rise of 25.7 (+/-7.3) mm Hg in the second session was associated with a significant loss in arterial vasoconstriction of -2.3 (+/-1.4) % (session I vs session II p=0.002). CONCLUSIONS:The myogenic response of the arterial wall in human retinal arterioles was significantly reduced during acute rise of blood glucose levels.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Blum M,Brändel C,Müller UAdoi
10.1177/112067210501500109subject
Has Abstractpub_date
2005-01-01 00:00:00pages
56-61issue
1eissn
1120-6721issn
1724-6016journal_volume
15pub_type
杂志文章abstract:PURPOSE:To report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). METHODS:We performed clinical and confocal scan on a patient who underwent DSAEK and phacoemulsification for Fuchs endothelial dystrophy and cataract. RESULTS:A...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6228
更新日期:2011-07-01 00:00:00
abstract::Purpose. To record the information used in order to make a retreatment decision in patients with exudative age-related macular degeneration (AMD) and to assess if an optical coherence tomography (OCT)-only follow-up clinic would suffice. Methods. Two hundred patients under treatment with intravitreal anti-vascular end...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000190
更新日期:2012-08-06 00:00:00
abstract:PURPOSE:To evaluate the clinical characteristics of the unusual late postoperative capsular block syndrome (CBS) and the effect of Nd:YAG laser posterior capsulotomy on visual acuity and refractive error as well as its possible complications. METHODS:In this retrospective cohort study, 12 eyes of 11 patients with late...
journal_title:European journal of ophthalmology
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更新日期:2015-01-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000988
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To report a case of posterior microphthalomos (PM) related to PRSS56 gene mutation with long term follow up with multimodal imaging findings. METHODS:Single retrospective case report. RESULTS:A 43-year old male patient presented in 2009 with bilateral reduced vision. Clinical examination and multimodal imagin...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-08-17 00:00:00
abstract:PURPOSE:To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. METHODS:194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
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更新日期:2020-09-21 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000442
更新日期:2014-07-01 00:00:00
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更新日期:2019-09-01 00:00:00
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journal_title:European journal of ophthalmology
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doi:
更新日期:1993-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1177/112067210901900220
更新日期:2009-03-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2016-06-10 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To describe the long-term clinical course of patients with low-pressure glaucoma (LPG) and to assess the risk factors for disease progression. METHODS:The Wills Eye Glaucoma Research Center retrospectively reviewed the charts of LPG patients with documented follow-up of >8 years between 2000 and 2013. Medical ...
journal_title:European journal of ophthalmology
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更新日期:2015-11-01 00:00:00
abstract:PURPOSE:Twenty-two people with a history of grass pollen allergic conjunctivitis were enrolled outside the pollen season in this study to compare the efficacy of 0.05% mequitazine eyedrops with topical 2% disodium cromoglycate. METHODS:This randomized, double-blind study compared right and left eyes. Subjects received...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/112067210001000103
更新日期:2000-01-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800405
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:To describe a rare presentation of pituitary apoplexy as unilateral abducens nerve palsy demonstrating the various presentations of the condition. METHODS:Case report. RESULTS:A 48-year-old man presented with isolated right abducens nerve palsy. Magnetic resonance imaging showed a large pituitary macroadenoma...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000136
更新日期:2010-01-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2004-11-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
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更新日期:2017-05-11 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800425
更新日期:2008-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-11-01 00:00:00
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更新日期:2020-11-06 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-01-27 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-07-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2013-09-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2009-07-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2020-05-01 00:00:00