Abstract:
:Ultrasound tissue characterization parameters of size and acoustic concentration can be used to sub-classify uveal melanoma and estimate the patient's risk of death. Histologically determined microcirculation patterns have also been found to sub-classify uveal melanoma and predict patient's risk of death. This study examines the spatial relationship between tumor features detected by the two techniques. Three dimensional ultrasound images that depict the size and relative concentration of scattering elements in uveal melanoma within a range of approximately 50-120 microns were compared with PAS (without hematoxylin) stained histological sections graded and localized according to tumor microvascular patterns. Both ultrasound parameter imaging and histopathology were accomplished by workers masked to the other procedure. In three of five patients vascular networks were identified histopathologically. The predominant ultrasound feature seen in the regions of the histologically identified networks were clusters of scatterers in the range of approximately 50-80 microns. In the two cases without a network vascular pattern, lower range scatterers dominated the tumor volume. All the cases could be distinguished by the size and distribution of contiguous spatial clusters of acoustic scatterers. Scatterer size features detected in three dimensional ultrasound parameter images can identify tumor regions containing a specific microvascular pattern. Ultrasound tissue characterization features used to sub-classify uveal melanoma may have a biophysical basis related to patterns of tumor microcirculation.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Coleman DJ,Rondeau MJ,Silverman RH,Folberg R,Rummelt V,Woods SM,Lizzi FLsubject
Has Abstractpub_date
1995-04-01 00:00:00pages
96-106issue
2eissn
1120-6721issn
1724-6016journal_volume
5pub_type
杂志文章abstract:PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000504
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To describe a case of a 46-year-old woman with an asymptomatic history of unilateral multiple serous detachments of the retinal pigment epithelium (PED) in the right eye, treated with photodynamic therapy (PDT) with verteporfin for recent onset of subfoveal choroidal neovascularization (CNV) with chorioretinal ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:To describe a patient who developed diplopia, lagophthalmos and exposure keratopathy due to a large subconjunctival emphysema. METHODS:A 24-year-old man sustained an injury in his left eye from a compressed air hose. The patient complained of pain and diplopia. He underwent slit-lamp examination, funduscopy an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300113
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of oral prednisolone on visual outcomes and complications of scleral buckling (SB) in phakic eyes with acute rhegmatogenous retinal detachment (RRD). METHODS:In a randomized double-blind placebo-controlled trial, patients with acute RRD underwent SB. The treatment group received 1 mg/kg ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067211002000224
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To determine the microbial contamination of the irrigating fluids at the time of phacoemulsification after the use of topical povidone-iodine and antibiotics prophylaxis. METHODS:A total of 119 patients undergoing cataract surgery were enrolled in this prospective study. All patients received 5 mg/mL levofloxa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.8434
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) are angiogenic mediators that share a significant proinflammatory activity. Both substances have been suggested to play a key role in uveitis pathogenesis. The authors analyzed VEGF and IL-8 levels in the aqueous humor and serum of patients with...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700611
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:To report a case of a combined branch retinal artery and vein occlusion in a patient with hepatitis C treated with interferon and ribavirin. METHODS:A 29-year-old man with a 1-week history of sudden visual field defect and decrease of central visual acuity was examined. RESULTS:Ophthalmoscopy and fluorescein ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4623
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To report a case of posterior microphthalomos (PM) related to PRSS56 gene mutation with long term follow up with multimodal imaging findings. METHODS:Single retrospective case report. RESULTS:A 43-year old male patient presented in 2009 with bilateral reduced vision. Clinical examination and multimodal imagin...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120949756
更新日期:2020-08-17 00:00:00
abstract:PURPOSE:To investigate visual function and ocular features in children with attention deficit hyperactivity disorder (ADHD). METHODS:Fifty-one children underwent a detailed ophthalmologic evaluation. Thirty-two were diagnosed with ADHD, and 19 children with attention deficit disorder (ADD). The mean age was 9.9±3.1 ye...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000145
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To describe the natural course of type 2 idiopathic macular telangiectasia (MT) using spectral-domain optical coherence tomography (SD-OCT). METHODS:Analysis of the different stages of progression of type 2 MT during a period of 3 years using multimodal imaging, including SD-OCT correlated with angiographic an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000363
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To compare the performance of two different microcatheter systems, iTrack™ 250A and Glaucolight, in ab externo canaloplasty in three major categories: intraocular pressure reduction, drug therapy reintroduction, and evaluation of viscodilation over distension of the inner wall of Schlemm's canal. METHODS:A tot...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119833547
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To determine the safety and efficacy of photodynamic therapy with verteporfin (V-PDT) in the treatment of exudative idiopathic polypoidal choroidal vasculopathy (IPCV) lesions that were not suitable for laser photocoagulation. METHODS:This was a prospective, open label study in two centers involving 30 consecu...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/112067210601600506
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To estimate the incidence of retinopathy of prematurity and other ocular problems in a population of preterm infants. METHODS:This retrospective study included all infants with gestational age (GA) <32 weeks and birth weight (BW) <1500 g cared for in the neonatal intensive care unit (NICU) over a period of nin...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200610
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:To compare the results of viscocanalostomy with and without mitomycin-C (MMC). METHODS:Retrospective results of 15 standard viscocanalostomy (VCO) operations (Group 1) were compared with the prospective results of 15 VCO operations performed with intraoperative adjunctive MMC (Group 2). MMC (0.2 mg/mL) was app...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1177/112067210501500204
更新日期:2005-03-01 00:00:00
abstract:INTRODUCTION:To identify novel velocity waveform parameters of the ophthalmic artery and central retinal artery by computer-aided image processing of Doppler ultrasonography measurements, and to evaluate correlations between the waveform parameters and different demographics and disease severity of open-angle glaucoma ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119848259
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:The authors wondered whether the spectrum of endophthalmitis and the type of therapy had changed. METHODS:Files of patients who were operated upon for endophthalmitis between 1988 and 2000 were retrospectively analyzed. They were divided into Group 1 (operated upon 1988 to 1994) and Group 2 (1995 to 2000). RE...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600217
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To describe the impact that social media usage has on a group of retina specialists. MATERIALS AND METHODS:An anonymous online survey was sent to members of the Young Retina Forum who use the social media platform - Telegram. RESULTS:Of a total of 178 members, 100 responded (87 men and 13 wom...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119832186
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To review methods of assessing bulbar redness, particularly with respect to the practicality of comparing different rating systems. METHODS:The published literature was reviewed and discussed by a panel of experts and a narrative review prepared. RESULTS:Bulbar hyperemia is a common clinical sign and an impor...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.5301/ejo.5000626
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:While elevated intraocular pressure (IOP) is a major risk factor for glaucoma, only about 1% of patients with 25 mmHg develop the condition each year. Since a sizeable proportion of the ganglion cells are already lost when the visual field losses are apparent, the aim is to identify patients with elevated IOP i...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/112067210101102s05
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800104
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To evaluate the anatomic success rate, visual acuity (VA) changes, and complications of 23-G vitrectomy without associated scleral procedures for the treatment of primary rhegmatogenous retinal detachment (PRRD). METHODS:Patients diagnosed with PRRD were considered for inclusion. Patients with evidence of pr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000234
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To establish the real localization of rifabutin-related corneal deposits in a patient with human immunodeficiency virus (HIV) infection by in vivo HRT II confocal microscopy with related clinicopathologic implications. METHODS:Observational case report. After Siena University Institutional Review Board approva...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900327
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800225
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:We report spectral domain optical coherence tomography findings of the peripheral retina in a patient with senile (acquired) retinoschisis. METHODS:This is an observational case report. Spectral domain optical coherence tomography was performed to image the peripheral retina at the area of retinoschisis in a 7...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000610
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To assess the long-term anatomical and functional results of balloon buckle surgery for rhegmatogenous retinal detachment. PATIENTS AND METHODS:Twenty-five selected detachments with a single break or a group of breaks close together were treated with a temporary parabulbar balloon. Adhesion was obtained with t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100410
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To compare the efficacy of selective laser trabeculoplasty (SLT) to argon laser trabeculoplasty (ALT) as treatment and retreatment to lower intraocular pressure (IOP) in patients with uncontrolled open-angle glaucoma (OAG) on maximally tolerated medication therapy with a follow-up of 12 months. METHODS:A total...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210901900317
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000851
更新日期:2017-05-11 00:00:00
abstract:PURPOSE:To describe a case of bilateral eyelid-confined giant cell angiofibroma (GCAF) in a patient with a slowly progressive bilateral eyelid swelling. METHODS:A 40-year-old man with a 5-year history of slowly progressive bilateral eyelid swelling, severe functional impairment, and bilateral cosmetic deformity was st...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000608
更新日期:2010-11-01 00:00:00
abstract::Electroretinogram (ERG) changes with age have been studied widely, but there is no general agreement about the age at which ERG parameters reach adult values. We studied 296 eyes from 148 healthy subjects, divided into 14 age groups, ranging from 1 week to 21 years. Although most of the maturational changes or ERG tak...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To evaluate rotational stability, astigmatism correction, visual outcomes, and patient satisfaction after implantation of the toric intraocular lens (IOL) Torica-aA following cataract extraction over a 6-month follow-up period. METHODS:This prospective observational study enrolled 40 eyes of 26 patients presen...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000696
更新日期:2016-06-10 00:00:00