Abstract：
PURPOSE:Twenty-two people with a history of grass pollen allergic conjunctivitis were enrolled outside the pollen season in this study to compare the efficacy of 0.05% mequitazine eyedrops with topical 2% disodium cromoglycate. METHODS:This randomized, double-blind study compared right and left eyes. Subjects received 2% disodium cromoglycate eyedrops in one eye and mequitazine vehicle in the fellow eye 4 times daily for 4 days. For the last instillation, mequitazine vehicle was replaced by one drop of 0.05% mequitazine and 15 min later a conjunctival provocation test (CPT) with grass pollen was performed. RESULTS:The sum of the scores for hyperemia and itching, and total composite score were lower after 0.05% mequitazine than after 2% disodium cromoglycate (p < 0.0001 in each case). The allergen threshold dose which elicited a positive allergic response was higher in the mequitazine group (p < 0.001). Both treatments showed good tolerance upon instillation. No adverse events related to study treatment occurred. CONCLUSIONS:These results demonstrate the superior efficacy of a single drop of 0.05% mequitazine 15 min before CPT compared with 2% disodium cromoglycate 4 times daily for 4 days.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Dupin O,Trinquand C,Persi L,Bousquet J,Robert F,Arnaud Bdoi
10.1177/112067210001000103subject
Has Abstractpub_date
2000-01-01 00:00:00pages
15-21issue
1eissn
1120-6721issn
1724-6016journal_volume
10pub_type
临床试验,杂志文章,随机对照试验abstract：PURPOSE:To describe the unusual complication of retinal pigment epithelial (RPE) tear after intravitreal ranibizumab (Lucentis) for subfoveal fibrovascular pigment epithelial detachment (PED) and its effective management. METHODS:Chart review for case report of RPE tear after ranibizumab. RESULTS:An inferior RPE tear...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700432
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy, safety, and tolerability of Timogel® preservative-free once daily compared to timolol 0.5% ophthalmic solution bid in patients with ocular hypertension (OHT) and patients with primary open-angle glaucoma (POAG). METHODS:A total of 75 patients with OHT and patients with POAG treated wi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000006
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Increased PGE2 production by the iris and ciliary body regulate intraocular pressure (IOP) in vivo. Various cholinergic and adrenergic compounds are traditionally used as antiglaucoma drugs, and their effect on IOP reduction is antagonised by cyclooxygenase inhibitors, indicating a role for eicosanoids in their...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210301300103
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To describe a new technique for remnant removal in cases of posterior capsular rupture during cataract surgery and Soemmering ring extraction during intraocular lens (IOL) removal. METHODS:An IOL injector, inserted into the anterior chamber, provides a new exit for residual lens fragments. Passive fluid flow, ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000962
更新日期：2017-06-26 00:00:00
abstract：:Retinal ganglion cells (RGCs) undergo programmed cell death (apoptosis) after axonal injury. This cell death is mediated by several mechanisms, including deprivation of neurotrophic factors, alterations in gene expression, and production of reactive oxygen species. However, death of RGCs is delayed after axonal injury...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To quantify the maximal level of temperature and the time the maximal temperature is achieved and correlate the temperature parameters to the mean rate of endothelial cell loss after standardized ultrasound delivery assisted with four viscoelastic substances or different temperature of balanced salt solution (B...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000851
更新日期：2017-05-11 00:00:00
abstract：PURPOSE:A pilot study was carried out to evaluate the practicality, reliability, and validity of an objective structured clinical examination (OSCE) for assessing the clinical skills and abilities of specialists in ophthalmology. METHODS:Ten unfolded OSCE style, criterion referenced questions were asked to nine candid...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210601600415
更新日期：2006-07-01 00:00:00
abstract：:Two cases of idiopathic sclerochoroidal calcification are reported with follow-up of two and ten years. In addition we have reviewed 102 cases of choroidal osteoma, including six misleading case reports which actually described idiopathic sclerochoroidal calcification and not choroidal osteoma. Clinical manifestation ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:In renal failure the incidence of pingueculae is significantly higher than in a comparable control group but there is no evidence that the calcific precipitation in renal failure is of a dystrophic nature. The lime salts are not located within the area of elastotic degeneration, a prerequisite for dystrophic degenerat...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：PURPOSE:To compare topographic indices of surface regularity in dry eye patients and in normal subjects (controls) and to investigate the short-term effect of lacrimal punctal plugs on these indices in dry eye patients. METHODS:The surface regularity index (SRI) and surface asymmetry index (SAI) of the TMS-2 corneal t...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210101100202
更新日期：2001-04-01 00:00:00
abstract：PURPOSE:To investigate color vision and its relation with the type of amblyopia and visual acuity of amblyopic eyes. METHODS:In this prospective study, 67 amblyopic eyes of 64 patients, aged from 4 to 13 years (mean 6.8 +/- 2.1) and 26 eyes of 13 control subjects aged from 5 to 13 years (mean 7.3 +/- 1.6) were examine...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210001000113
更新日期：2000-01-01 00:00:00
abstract：PURPOSE:To evaluate changes in anterior chamber morphology with the Pentacam anterior segment analyzer and gonioscopy after laser peripheral iridotomy (LPI) in patients with primary angle closure glaucoma and narrow angle and to compare central corneal thickness measurements performed with Pentacam and ultrasound pachy...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000211
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:To evaluate the risk factors for posterior capsule rupture with or without vitreous loss (PCR +/- VL) in extracapsular cataract extraction (ECCE). METHODS:The charts of 2794 consecutive patients who had ECCE with or without intraocular lens implantation between January 1992 and December 1997 were reviewed retr...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/112067210001000306
更新日期：2000-07-01 00:00:00
abstract：PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000504
更新日期：2010-09-01 00:00:00
abstract：:Astigmatic changes in three series of cataract surgical procedures were compared. The first two series comprised eyes having a manual extracapsular cataract extraction (ECCE) through a 12.0 mm or 8.0 mm incision and implant of a PMMA posterior chamber lens. The third series comprised eyes having phacoemulsification th...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：PURPOSE:To evaluate the effect of IOP lowering on the capillary density of optic nerve head and retinal nerve fiber layer in patients with primary open angle glaucoma. METHODS:Twenty eyes of 14 glaucomatous patients and 15 eyes of nine normal patients were enrolled. The most appropriate hypotonic treatment was applied...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120967233
更新日期：2020-10-29 00:00:00
abstract：BACKGROUND/AIMS:To assess structural and functional outcomes of treatment with intravitreal aflibercept (®Eylea) for diabetic macular oedema in treatment-naïve patients. METHODS:Sixty-four eyes receiving intravitreal anti-vascular endothelial growth factor therapy were included in the data analysis of this retrospecti...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120925034
更新日期：2020-05-19 00:00:00
abstract：PURPOSE:This study aimed to investigate the role of protein peroxidation by detecting the serum levels of advanced oxidation protein products (AOPP), a novel marker for the degree of oxidative damage to proteins, and total thiol as a marker of antioxidant status in diabetic patients with or without diabetic retinopathy...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210801800521
更新日期：2008-09-01 00:00:00
abstract：:In 1958, Kearns and Sayre described a multisystem entity, now known as Kearns-Sayre syndrome (KSS). The syndrome is defined as exhibiting a triad of thus far unexplained degenerative conditions: progressive external ophthalmoplegia, retinal pigmentary degeneration, and heart block. Commonly accompanying findings inclu...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To evaluate the choroidal vascularity index of eyes for acute and chronic central serous chorioretinopathy patients using swept-source optical coherence tomography generated en-face scans. METHODS:This was a retrospective study, in which slabs of en-face optical coherence tomography scans, at 5 μm intervals, s...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120908719
更新日期：2020-02-27 00:00:00
abstract：PURPOSE:To describe a clinical case of corneoscleral xanthogranuloma, a rare manifestation of juvenile xanthogranuloma, and xanthoma disseminatum, which responded well to chemotherapy. METHODS:Interventional case report and literature search. RESULTS:A 9-year-old female patient with a disseminated disease showed comp...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119832187
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To describe a rare presentation of pituitary apoplexy as unilateral abducens nerve palsy demonstrating the various presentations of the condition. METHODS:Case report. RESULTS:A 48-year-old man presented with isolated right abducens nerve palsy. Magnetic resonance imaging showed a large pituitary macroadenoma...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000136
更新日期：2010-01-01 00:00:00
abstract：:A 62-year-old female developed pseudophakic bullous keratopathy after cataract surgery and underwent Descemet stripping automated endothelial keratoplasty (DSAEK). Intraoperatively, a white opacified pre-Descemet's layer was noticed after scoring and removal of trypan blue stained Descemet's membrane (DM), and endothe...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120974271
更新日期：2020-11-30 00:00:00
abstract：:Purpose. Extraocular muscle (EOM) pulleys are important in eye movement physiology and may play a role in the outcome of strabismus surgery. Few studies have evaluated "normal" position of EOM pulleys. We sought to assess intraoperatively medial rectus (MR) pulley location and variations in a prospective observational...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000187
更新日期：2013-01-21 00:00:00
abstract：PURPOSE:To describe the long-term clinical course of patients with low-pressure glaucoma (LPG) and to assess the risk factors for disease progression. METHODS:The Wills Eye Glaucoma Research Center retrospectively reviewed the charts of LPG patients with documented follow-up of >8 years between 2000 and 2013. Medical ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000624
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:To present outcome data on low risk primary trabeculectomy augmented with low dose peroperative (0.1 mg/mL for 1 minute) mitomycin-C (MMC). METHODS:Retrospective case note review. All cases of trabeculectomy utilizing MMC augmentation at a concentration of 0.1 mg/mL with an application time of 1 minute and at ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:To report a case of a combined branch retinal artery and vein occlusion in a patient with hepatitis C treated with interferon and ribavirin. METHODS:A 29-year-old man with a 1-week history of sudden visual field defect and decrease of central visual acuity was examined. RESULTS:Ophthalmoscopy and fluorescein ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.4623
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To compare the results of viscocanalostomy with and without mitomycin-C (MMC). METHODS:Retrospective results of 15 standard viscocanalostomy (VCO) operations (Group 1) were compared with the prospective results of 15 VCO operations performed with intraoperative adjunctive MMC (Group 2). MMC (0.2 mg/mL) was app...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1177/112067210501500204
更新日期：2005-03-01 00:00:00
abstract：:The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
