Abstract：
PURPOSE:To present outcome data on low risk primary trabeculectomy augmented with low dose peroperative (0.1 mg/mL for 1 minute) mitomycin-C (MMC). METHODS:Retrospective case note review. All cases of trabeculectomy utilizing MMC augmentation at a concentration of 0.1 mg/mL with an application time of 1 minute and at least 1 year follow-up during the study period were included. Only first eyes were included. Patient demographics and postoperative course including complications, interventions, and outcomes were documented and analyzed. RESULTS:Fifty-nine trabeculectomies that met the inclusion criteria were identified. Mean age of cases was 70.8 years. Mean follow-up time was 19.3 months. Bleb leaks occurred in 16 (27.1%) cases. Only one case required surgical intervention in the form of resuturing after 14 days. At 1 year, there was a reduction in mean number of topical medications from 2.70 to a mean of 0.07. Unqualified success (intraocular pressure [IOP] at 1 year of less than 16 mmHg without medication) was achieved in 49 cases (83.1%). Mean IOP was reduced from the preoperative value of 23.1 mmHg (SD 5.8) to 13.5 mmHg (SD 5.0) (p<0.001). CONCLUSIONS:Our data suggest that a primary trabeculectomy augmented with a low dose of MMC is a safe and effective procedure for IOP reduction in patients with a low risk of trabeculectomy failure.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Alwitry A,Abedin A,Patel V,Moodie J,Rotchford A,King AJsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
971-6issue
6eissn
1120-6721issn
1724-6016pii
4828EFB2-186B-4DDA-A8B7-82BB6EA8EDCDjournal_volume
19pub_type
杂志文章abstract：INTRODUCTION:Preretinal hemorrhages can be located in subhyaloid or sub-internal limiting membrane (ILM) space. Though optical coherence tomography (OCT) may help to distinguish the exact location of hemorrhage in selected cases, it is often difficult to discern clinically. The purpose is to describe a novel clinical s...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
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journal_title：European journal of ophthalmology
pub_type： 杂志文章
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
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journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2005-09-01 00:00:00
abstract：PURPOSE:To discover the effect of detachment of the posterior vitreous cortex on pattern electroretinogram (PERG) P50 amplitudes in the uninvolved fellow eyes (FE) of patients with macular holes (MH), and to determine the prognostic value of the PERG in identifying the FE of patients with MH that could be at risk for t...
journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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更新日期：2012-03-01 00:00:00
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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更新日期：2003-01-01 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2014-05-01 00:00:00
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journal_title：European journal of ophthalmology
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doi：
更新日期：1994-07-01 00:00:00
abstract：PURPOSE:To evaluate epithelial healing and visual outcome after laser-assisted subepithelial keratectomy (LASEK) without alcohol de-epithelialization and to compare this technique to photorefractive keratectomy (PRK) in myopia. METHODS:In a series of 1953 patients undergoing bilateral myopic PRK, an epithelial flap co...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章
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journal_title：European journal of ophthalmology
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更新日期：2013-05-01 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2014-05-01 00:00:00
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：European journal of ophthalmology
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更新日期：2015-07-30 00:00:00
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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更新日期：2017-05-11 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2006-07-01 00:00:00
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journal_title：European journal of ophthalmology
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更新日期：2017-08-30 00:00:00
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journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
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journal_title：European journal of ophthalmology
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更新日期：2013-07-01 00:00:00
abstract：INTRODUCTION:The aim of the study was to evaluate complications of cataract surgery in eyes filled with silicone oil. METHODS:This retrospective, noncomparative, consecutive case series analyzed medical files of patients with eyes filled with silicone oil undergoing cataract surgery. Phacoemulsification with posterior...
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更新日期：2018-07-01 00:00:00
