Transplantation failure due to inadvertent reversal of human donor corneas.

Abstract:

PURPOSE:To emphasize and create awareness of the possibility of inadvertently grafting an inverted corneal button and describe 4 cases that showed this phenomenon on human donor corneas during preservation and transportation from an eye bank. METHODS:Three out of 4 tissues showed inadvertent inversion during transportation and 1 was identified as inverted during preservation in the eye bank. Out of the 3 tissues that were shipped, 2 tissues were transplanted and 1 was identified as inverted prior to transplantation and shipped back to the eye bank. RESULTS:Four tissues showed inversion at different time points. The anatomy was clearly visible with a naked eye that showed the presence of trabecular meshwork on its outside along with some residual choroid. The endothelial cell count was in the range of transplantation without any mortality even after inversion. The inverted corneas showed a mountain-like shape with grooves as compared to the normal cornea. CONCLUSIONS:Previous reports have identified tissue inversion post-transplantation. We describe inadvertent inversion of donor tissues during preservation and transportation from an eye bank. It is recommended to check the presence of corneo-scleral rim, trabecular meshwork, grooves, and residues of choroid if present inside or outside before transplantation to ensure accurate grafting and avoid transplantation failures.

journal_name

Eur J Ophthalmol

authors

Parekh M,Ruzza A,Elbadawy H,Ferrari S,Salvalaio G,Camposampiero D,Ponzin D

doi

10.5301/ejo.5000711

subject

Has Abstract

pub_date

2016-02-15 00:00:00

pages

e21-3

issue

2

eissn

1120-6721

issn

1724-6016

pii

8B2E089F-D124-4335-9CC2-DC318E4414F9

journal_volume

26

pub_type

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