Diabetic retinopathy and cerebral hemodynamic impairment in type II diabetes.

Abstract:

PURPOSE:To assess whether a screening method based on transcranial Doppler (TCD) examination could detect signs of brain hemodynamic impairment in non-insulin-dependent diabetic patients with retinal microangiopathy of varying severity, asymptomatic for cerebrovascular diseases. METHODS:We studied 86 patients stratified according to the presence of proliferative diabetic retinopathy (PDR: 29 cases), background retinopathy (BDR: 32 cases) and no diabetic retinopathy (NDR: 25 patients). TCD was performed to record mean flow velocity and pulsatility index values in the middle cerebral (MCA), anterior cerebral (ACA) and ophthalmic arteries (OA), at rest. It was also employed to evaluate the cerebral vasodilatory response to a breath-holding test: the maximum percentage MCA flow velocity increase during the test was taken as an index of cerebrovascular reactivity. Fifty healthy subjects were studied to establish control values. Analysis of variance was used to test inter-group differences. The regression test was applied to define the relationship between TCD parameters and age and disease duration. RESULTS:No significant differences were found between controls and the whole group of patients with respect to TCD parameters. However, subgroup analysis showed PDR patient had a significantly higher pulsatility index and lower cerebrovascular reactivity than BDR and NDR patients. This difference was not explained by the effect of age or disease duration, being greatest in patients under sixty. CONCLUSIONS:These findings seem to confirm the hypothesis of a silent cerebral microangiopathy affecting diabetic patients, with concomitant signs of microangiopathic damage in other districts.

journal_name

Eur J Ophthalmol

authors

Lippera S,Gregorio F,Ceravolo MG,Lagalla G,Provinciali L

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

156-62

issue

2

eissn

1120-6721

issn

1724-6016

journal_volume

7

pub_type

杂志文章
  • Diabetes and blindness in people with diabetes in Hungary.

    abstract:INTRODUCTION::The purpose of the study was to estimate the number of people with diabetes mellitus, the prevalence of diabetes mellitus and the prevalence of blindness and severe visual impairment among people with diabetes mellitus in Hungary based on our recent national representative survey. METHODS::Altogether 105...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1120672118811738

    authors: Tóth G,Szabó D,Sándor GL,Nagy ZZ,Karadeniz S,Limburg H,Németh J

    更新日期:2019-03-01 00:00:00

  • Swept-source optical coherence tomography angiography vitreo-retinal segmentation in proliferative diabetic retinopathy.

    abstract:PURPOSE:To identify a new cortical vitreous segmentation protocol for non invasive standardised investigation of Neovascularisation (NV) with detection of regression of NV activity in Proliferative Diabetic Retinopathy (PDR). DESIGN:Retrospective study. PARTICIPANTS:One hundred and eighty-six eyes of 93 consecutive d...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120944028

    authors: Papayannis A,Tsamis E,Stringa F,Iacono P,Battaglia Parodi M,Stanga PE

    更新日期:2020-07-28 00:00:00

  • Outcome of phacoemulsification in previously vitrectomized myopic eyes with axial length greater than 26 mm.

    abstract:PURPOSE:To determine the outcome, including the intraoperative and postoperative complications, of phacoemulsification with intraocular lens (IOL) implantation in myopic eyes with axial length of 26 mm or more that had undergone previous pars plana vitrectomy (PPV). METHODS:This prospective study comprised 37 highly m...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2010.6096

    authors: Gupta M,Lascaratos G,Syrogiannis A,Verma S

    更新日期:2011-07-01 00:00:00

  • Automated gonioscopy photography for iridocorneal angle grading.

    abstract:PURPOSE:The aim of this study is to assess the agreement between manual and automated gonioscopy for iridocorneal angle opening. METHODS:The research is a cross-sectional observational study. Manual and automated gonioscopy were performed to consecutive patients in a glaucoma clinic. Iridocorneal angle opening grading...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118806436

    authors: Teixeira F,Sousa DC,Leal I,Barata A,Neves CM,Pinto LA

    更新日期:2020-01-01 00:00:00

  • Measuring the lacunar sulci as a new indicator of shrinkage of the ocular surface.

    abstract:PURPOSE:To present a new indicator that measures the sulci of the lacrimal lake of the eye according to the degrees of ocular abduction at which they vanish. This new approach will help determine the severity and progression of mucosal retraction in ocular surface diseases. METHODS:A total of 181 eyes of 94 healthy pe...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210101100303

    authors: Murube J,Chenzhuo L,Murube E,Rivas L,Shalaby O

    更新日期:2001-07-01 00:00:00

  • Surgical repair of large cyclodialysis clefts.

    abstract:PURPOSE:To describe a new surgical technique to effectively close large (>180 degrees) cyclodialysis clefts. METHODS:Our method involves the use of procedures commonly associated with repair of retinal detachment and complex cataract extraction: phacoemulsification with placement of a capsular tension ring followed by...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000868

    authors: Gross JB,Davis GH,Bell NP,Feldman RM,Blieden LS

    更新日期:2017-05-11 00:00:00

  • Late postoperative capsular block syndrome: a case series studied before and after Nd:YAG laser posterior capsulotomy.

    abstract:PURPOSE:To evaluate the clinical characteristics of the unusual late postoperative capsular block syndrome (CBS) and the effect of Nd:YAG laser posterior capsulotomy on visual acuity and refractive error as well as its possible complications. METHODS:In this retrospective cohort study, 12 eyes of 11 patients with late...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000507

    authors: Huerva V,Sánchez MC,Ascaso FJ,Soldevila J

    更新日期:2015-01-01 00:00:00

  • Peripheral choroidal neovascularization.

    abstract::Peripheral choroidal neovascularization can result in an elevated subretinal lesion which can simulate a choroidal tumor. We reviewed 8 eyes with 11 peripheral areas of subretinal fluid and exudate which were subsequently determined to be secondary to peripheral choroidal neovascularization. Previous reports of periph...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Vine AK,Johnson MW

    更新日期:1996-01-01 00:00:00

  • Sensitivity and specificity of machine learning classifiers and spectral domain OCT for the diagnosis of glaucoma.

    abstract::Purpose. To investigate the sensitivity and specificity of machine learning classifiers (MLC) and spectral domain optical coherence tomography (SD-OCT) for the diagnosis of glaucoma. Methods. Sixty-two patients with early to moderate glaucomatous visual field damage and 48 healthy individuals were included. All subjec...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000183

    authors: Vidotti VG,Costa VP,Silva FR,Resende GM,Cremasco F,Dias M,Gomi ES

    更新日期:2012-06-15 00:00:00

  • Needle revision outcomes after glaucoma filtering surgery: survival analysis and predictive factors.

    abstract:PURPOSE:To evaluate the efficacy and safety of needle revision and examine factors predictive of failure. METHODS:In total, 157 eyes of 131 patients that underwent needle revision augmented with either 5-fluorouracil or betamethasone for trabeculectomy failure were included in this retrospective study. Complete failur...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119830861

    authors: Rabiolo A,Marchese A,Bettin P,Monteduro D,Galasso M,Dolci MP,Di Matteo F,Fiori M,Ciampi C,Bandello F

    更新日期:2020-03-01 00:00:00

  • Effect of recipient corneal pathology on Pascal tonometer and Goldmann tonometer readings in eyes after penetrating keratoplasty.

    abstract:PURPOSE:To assess the influence of recipient corneal pathology on the performance of the Pascal dynamic contour tonometer (PDCT) (Swiss Microtechnology AG) by comparing it to Goldmann applanation tonometry (GAT) in post-penetrating keratoplasty (PKP) eyes. METHODS:Intraocular pressure (IOP) was measured in 40 post-PKP...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000104

    authors: Papastergiou GI,Kozobolis V,Siganos DS

    更新日期:2010-01-01 00:00:00

  • Fluorescein angiography--is it safe to use in a pregnant patient?

    abstract::We sent questionnaires to 424 retina specialists in order to compile information on the use of fluorescein angiography in pregnant women. Four-hundred and three specialists responded. Of these, 313 (78%) had never performed fluorescein angiography on a pregnant woman. Ninety specialists (22%) had performed at least on...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Olk RJ,Halperin LS,Soubrane G,Coscas G

    更新日期:1991-04-01 00:00:00

  • Aggressive skull base metastasis from uveal melanoma: a clinicopathologic study.

    abstract:PURPOSE:We present the clinical, pathologic, and genetic findings of the first reported case of choroidal melanoma that developed a late recurrence and aggressive metastasis to the skull base without evidence of hepatic involvement. METHODS:Retrospective chart review and clinicopathologic correlation of ocular and bra...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000468

    authors: Yonekawa Y,Kim IK,Gragoudas ES,Njauw CN,Tsao H,Jakobiec FA,Stacy RC

    更新日期:2014-09-01 00:00:00

  • Keratoconus and Fuchs' heterochromic iridocyclitis: a coincidence or a defect during embryogenesis?

    abstract:PURPOSE:We aimed to discuss the possible role of developmental embryologic factors in neural crest cells in the aetiology of keratoconus and Fuchs' heterochromic iridocyclitis by presenting this case. CASE REPORT:We diagnosed bilateral keratoconus and unilateral Fuchs' heterochromic iridocyclitis in a 19 year old wome...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210101100114

    authors: Yagci A,Uretmen O,Egrilmez S,Gunenc U,Kusbeci T

    更新日期:2001-01-01 00:00:00

  • Corneal endothelium in patients with diabetes mellitus: a historical cohort study.

    abstract:PURPOSE:Retinopathy is the major cause of ocular morbidity in patients with diabetes mellitus. Chronic hyperglycemia spares no organ and can affect the morphology and function of the various corneal layers, compromising its transparency. This study was conducted to associate the status of corneal endothelium to diabete...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210901900307

    authors: Shenoy R,Khandekar R,Bialasiewicz A,Al Muniri A

    更新日期:2009-05-01 00:00:00

  • Variations in the blood flow of the human optic nerve head.

    abstract::Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF tech...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Osuský R,Schoetzau A,Flammer J

    更新日期:1997-10-01 00:00:00

  • Intravitreal steroid slow-release device replacing repeated intravitreal triamcinolone injections for sympathetic ophthalmia.

    abstract:PURPOSE:To report on the intraocular use of a steroid slow-release device in an attempt to avoid multiple intraocular triamcinolone injections in chronic sympathetic ophthalmia. METHODS:A 47-year-old patient with sympathetic ophthalmia had received 17 intravitreal triamcinolone injections to suppress the uveitis, to i...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800531

    authors: Jonas JB,Rensch F

    更新日期:2008-09-01 00:00:00

  • Ocular complications of Garcinia cambogia extract diet pills: Case report.

    abstract:BACKGROUND:Garcinia cambogia contains hydroxycitric acid. Hydroxycitric acid is a potent competitive inhibitor of adenosine triphosphate citrate lyase which is a key enzyme in the synthesis of fatty acids. Hydroxycitric acid also regulates the level of serotonin. In these regards, hydroxycitric acid has been reported t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119872364

    authors: Cho HK,Han YS,Park JM

    更新日期:2020-11-01 00:00:00

  • Cataract surgery combined with intravitreal injection of triamcinolone acetonide.

    abstract:PURPOSE:To evaluate whether the addition of cataract surgery to an intravitreal injection of triamcinolone acetonide markedly increases frequency and spectrum of complications. METHODS:The comparative nonrandomized clinical interventional investigation included a study group of 60 eyes (56 patients) undergoing catarac...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1177/112067210501500303

    authors: Jonas JB,Kreissig I,Budde WM,Degenring RF

    更新日期:2005-05-01 00:00:00

  • Rituximab in the treatment of Susac's syndrome: Report of a case.

    abstract:SIGNIFICANCE:Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120924545

    authors: Monferrer-Adsuara C,Remolí-Sargues L,Hernández-Bel L,Gracia-García A,Hernández-Garfella ML,Cervera-Taulet E

    更新日期:2020-05-07 00:00:00

  • Treatment of acute bacterial conjunctivitis with topical lomefloxacin 0.3% compared to topical ofloxacin 0.3%.

    abstract:PURPOSE:The main purpose of this prospective study was to compare the efficacy, local tolerance, and safety of topical lomefloxacin 0.3% and topical ofloxacin 0.3% in the treatment of acute bacterial conjunctivitis. PATIENTS AND METHODS:Forty patients with acute bacterial conjunctivitis were included in a randomized, ...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Tabbara KF,El-Sheikh HF,Islam SM,Hammouda E

    更新日期:1999-10-01 00:00:00

  • Outcome of pediatric cataract surgery with intraocular injection of triamcinolone acetonide: Randomized controlled trial.

    abstract:PURPOSE::To evaluate the use of intraocular injection of triamcinolone acetonide in pediatric cataract surgery with or without intraocular lens implantation as a vitreous dye to ensure a complete anterior vitrectomy and evaluate its effect on postoperative ocular inflammation, infection, posterior capsule opacification...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1120672117754168

    authors: Allam G,Ellakkany R,Ellayeh A,Mohsen T,Abouelkheir HE,Gaafar W

    更新日期:2018-11-01 00:00:00

  • Choroidal and peripapillary retinal nerve fiber layer thickness in adults with anisometropic amblyopia.

    abstract:PURPOSE:To evaluate choroidal thickness, macular thickness, and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopic eyes compared to fellow and normal control eyes using high-definition spectral-domain optical coherence tomography (SD-OCT). METHODS:Fifty-four without any systemic problem and ocular d...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000594

    authors: Kantarci FA,Tatar MG,Uslu H,Colak HN,Yildirim A,Goker H,Gurler B

    更新日期:2015-09-01 00:00:00

  • Graded superior oblique tendon suture lengthening: A novel procedure.

    abstract:PURPOSE:Literature regarding different superior oblique (SO) weakening procedures showed variable results. Here, we aim to evaluate the effect of a novel superior oblique tendon suture lengthening (SOSL) procedure on weakening of SO in patients with A-pattern exotropia associated with dissociated vertical deviation and...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120968726

    authors: Xia W,Wu L,Yao J,Wen W,Wang X,Jiang C,Li L,Zhao C

    更新日期:2020-11-11 00:00:00

  • Bottle-cork injury to the eye: a review of 13 cases.

    abstract:PURPOSE:To analyze the anatomic and functional consequences of wine-cork injury to the eye in relation to the patient's age and the type of cork and wine. METHODS:We retrospectively studied 13 patients, six women and seven men, presenting to our department with bottle-cork injury to the eye between January 1999 and Ju...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210301300308

    authors: Cavallini GM,Lugli N,Campi L,Pagliani L,Saccarola P

    更新日期:2003-04-01 00:00:00

  • Induction of controlled wound healing with PMMA segments in the deep stroma in corneas of hens.

    abstract:PURPOSE:Polymethylmethacrylate (PMMA) segments are normally used in additive surgery to treat both corneal ectasia post laser-assisted in situ keratomileusis and keratoconus. The aim of this work was to develop an experimental animal model to induce wound healing in the deep stroma in corneas of hens. METHODS:PMMA seg...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000108

    authors: Merayo-Lloves J,Blanco-Mezquita T,Ibares-Frias L,Fabiani L,Alvarez-Barcia A,Martinez-Garcia C

    更新日期:2010-01-01 00:00:00

  • Visual acuity at presentation in the second eye versus first eye in patients with exudative age-related macular degeneration.

    abstract:PURPOSE:To assess the difference in best-corrected visual acuity (BCVA) at presentation between the first and second eye in patients with bilateral neovascular age-related macular degeneration (AMD). METHODS:We reviewed the charts of all patients who had a clinical examination for neovascular AMD at the University Eye...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000649

    authors: Chevreaud O,Semoun O,Blanco-Garavito R,Kamami-Levy C,Merle B,Jung C,Querques G,Souied EH

    更新日期:2016-01-01 00:00:00

  • Dacryo-fornix-rhinostomy with two flaps.

    abstract::The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Murube del Castillo J,Martinez Baradas A,Hernandez King J,Cruz Vilella ME,Bahamon Caycedo M

    更新日期:1992-04-01 00:00:00

  • Symmetric bimanual phacofragmentation: a new approach for nucleus disassembly.

    abstract:PURPOSE:To describe a new technique to split the lens nucleus inside the capsular bag, using a novel pair of instruments. METHODS:Two identical instruments are employed on the horizontal axis to promote nuclear splitting into 2 or more fragments. Each instrument has a portion that functions as a hook (H); an anterior ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000567

    authors: Jacobovitz S,Roitberg M,Massote V,Martins B,Vasconcelos-Santos DV

    更新日期:2015-07-01 00:00:00

  • New surgical approach for sutureless scleral fixation.

    abstract:PURPOSE:The aim of this article is to describe a novel surgical technique for sutureless scleral fixation of an intraocular lens using the newly developed FIL SSF Carlevale IOL (Soleko, Italy). METHODS:Four eyes of four patients with poor capsular support were recruited to our study, three resulting from intraocular l...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120902020

    authors: Veronese C,Maiolo C,Armstrong GW,Primavera L,Torrazza C,Della Mora L,Ciardella AP

    更新日期:2020-05-01 00:00:00